Noch ein Wort über Frank

Heinrich Graetz

The Gentleman's magazine library : being a classified collection of the chief contents of the Gentleman's magazine from 1731 to 1868 /

Includes bibliographical references.

Frank and Rufus, or, Obedience and disobedience /

Mode of access: Internet.

Frank : a sequal to Frank in early lessons /

Sequel to: Frank in early lessons.

Terrorism : laws cited imposing sanctions on nations supporting terrorism : fact sheet for the Honorable Frank R. Lautenberg, United States Senate /

"B-226205"--P. [1].

CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappa B

An understanding of the biochemical control of dendritic cell (DC) differentiation/activation is essential for improving T cell immunity by various immunotherapeutic approaches, including DC immunization. Ligation of CD40 enhances DC function, including conditioning for CTL priming. NF-kappaB, and particularly RelB, is an essential control pathway for myeloid DC differentiation. Furthermore, RelB regulates B cell Ag-presenting function. We hypothesized that CD40 ligand (CD40L) and TNF-alpha, which differ in their capacity to condition DC, would also differ in their capacity to activate NF-kappaB. DC differentiated for 2 days from monocytes in the presence of GM-CSF and IL-4 were used as a model, as NF-kappaB activity was constitutively low. The capacity of DC to activate T cells following CD40L treatment was enhanced compared with TNF-alpha treatment, and this was NF-kappaB dependent. Whereas RelB/p50 translocation induced by TNF-alpha was attenuated after 6 h, RelB/p50 nuclear translocation induced by CD40L was sustained for at least 24 h. The mechanism of this difference related to enhanced degradation of IkappaBalpha following CD40L stimulation. However, NF-kappaB activation induced by TNF-alpha could be sustained by blocking autocrine IL-10. These data indicate that NF-kappaB activation is essential for T cell activation by DC, and that this function is enhanced if DC NF-kappaB activation is prolonged. Because IL-10 moderates DC NF-kappaB activation by TNF-alpha, sustained NF-kappaB activation can be achieved by blocking IL-10 in the presence of stimuli that induce TNF-alpha.

Gunder Frank revisitado : um “sistema mundo” francamente único

Revista Lusófona de Ciências Sociais

O monstro e o duplo na criação cénica de Still Frank

Esta reflexão concretiza o Trabalho de Projecto que consiste na criação e encenação de um concerto intitulado Still Frank, com textos originais do poeta e dramaturgo Daniel Jonas e música de Rui Lima, Sérgio Martins e Pedro Cardoso. O espectáculo está inserido no programa da companhia Teatro Bruto e foi apresentado no TeCA – Teatro Carlos Alberto, em Dezembro de 2010, na cidade do Porto. Pretendo com a criação deste objecto cénico reflectir sobre a dualidade intrínseca ao processo de criação, na relação do criador com a criatura, do encenador com o espectáculo, do actor com a personagem, do real com a ficção. A criação como algo que, sendo proveniente do indivíduo, posteriormente ganha forma numa entidade autónoma que sobrevive ao sujeito a partir do qual se originou e se duplicou e com o qual partilha uma identificação. O conceito de duplo, de monstro e o mito «Frankenstein» estarão na base de toda a pesquisa e fundamentação para a criação do espectáculo Still Frank e, na minha reflexão teórica, devidamente distanciada do objecto cénico criado. Mas este trabalho não se detém somente na análise e reflexão do processo de encenação de Still Frank; ele consubstancia o meu percurso enquanto encenadora, cenógrafa e figurinista, indissociável do projecto artístico da companhia Teatro Bruto, nascida nos anos noventa, na cidade do Porto, e do trabalho de partilha e identificação artística de um núcleo de criadores com quem tenho colaborado.

Report on the scientific results of the voyage of H.M.S. Challenger during the years 1873-76 under the command of Captain George S. Nares ... and the late Captain Frank Tourle Thomson, R.N.

Botany v.2=pt.4 (1886)