The English dialect dictionary, being the complete vocabulary of all dialect words still in use, or known to have been in use during the last two hundred years. Founded on the publications of the English Dialect Society and on a large amount of material never before printed.

Includes bibliography.

A glossary of Cornish names, ancient and modern, local, family, personal, &c.: 20,000 Celtic and other names, now or formerly in use in Cornwall:

Mode of access: Internet.

Are you a bromide? : or, The sulphitic theory expounded and exemplified according to the most recent researches into the psychology of boredom, including many well-known bromidioms now in use /

"This essay is reprinted, with revisions and additions, from 'The sulphitic theory,' published in 'the Smart set' for April, 1906."

The new Yale song-book : a collection of songs in use by the Glee Club and students of Yale University /

Includes photographs of the Yale campus.

A Manual of Customs, Precedents and Forms, in Use in the Assembly of Wisconsin

Mode of access: Internet.

Development of vehicle-in-use sub-limit maneuvers /

Mode of access: Internet.

Motion devices for linear and angular oscillation and for abrupt acceleration studies on human subjects (impact), a description of facilities in use and proposed;

Includes bibliographies.

Practical pharmacy and prescribing for students of medicine : being the course in use at St. Bartholomew's Hospital /

Interleaved.

The South Australian system of conveyancing by registration of title, with instructions for the guidance of parties dealing, illustrated by copies of the books and forms in use in the Land Titles Office. To which is added the South Australian Real Property Act as amended in the sessions of 1858, with a copious index by Henry Gawler. Adelaide, Printed at the Register and Observer Printing Offices, 1859.

Mode of access: Internet.

A catalogue of the indigenous and exotic plants growing in Ceylon, distinguishing the several esculent vegetables, fruits, roots and grains; together with a sketch of the divisions of genera and species in use amongst the Singhalese. Also an outline of the Linnaean sexual system of botany: in the English and Singhalese languages. For the use of the Singhalese.

"Additions" and "Corrections": [4] p. at end.

Graduate attributes in relation to curriculum design and delivery in a Bachelor of Materials Engineering Programme

This paper presents a critical analysis of the Bachelor of Materials Engineering programme compared with the expectations of the Institution of Engineers Australia (IEAust) and of UQ. To set the scene, the graduate attributes are listed, the programme framework is presented and the educational culture and available facilities are described Then, the programme delivery is described; this includes an analysis of the learning opportunities that allow students to develop the graduate attributes. Finally, an assessment is made of programme outcomes relating to graduate attributes.

Changes in use of disease-modifying anti-rheumatic drugs in Australia over the period 1992-2004

Purpose Evidence is growing that early use of disease-modifying anti-rheumatic drugs (DMARDs) and combinations of these drugs provide optimal care for people with rheumatoid arthirits. The aim of this study was to describe objectively the pattern of consumption of DMARDs in the Australian community (community-based prescribing, specialist and general practitioner) 1992-2004, and to compare this with prescribing patterns reported in other countries. Method Dispensing statistics from the Pharmaceutical Benefit Scheme (PBS-Australia's universal prescription subsidy scheme) were analysed and temporal trends evaluated. Drug consumption was calculated as the number of dispensed defined daily doses (DDD)/1000 inhabitants/day (WHO ATC/DDD classification 2005). Results The consumption of DMARDs in the Australian community increased steadily from 2.6 DDD/1000 inhabitants/ day in 1992 to 5.5 DDD/1000 inhabitants/day. Over the period 1992-2004, methotrexate (MTX) was the most commonly used DMARD (from 0.6 to 3.0 DDD/1000 inhabitants/day). Consumption of gold (parentcral and oral) and penicillamine declined during this time. The inclusion of leflunomide on the PBS in 2000 contributed to the increase in DMARD usage. Conclusion Use of DMARDs within the Australian community has increased in recent years, coinciding with the change in guidelines for therapy for rheumatoid arthritis (RA) to earlier use of DMARDs and the more common use of combinations. This study used DDD methodology to quantify trends for DMARD consumption and these trends are broadly consistent with international prescribing patterns assessed using different methodologies. Copyright (c) 2006 John Wiley & Sons, Ltd.

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif

The cyclotides are a family of circular proteins with a range of biological activities and potential pharmaceutical and agricultural applications. The biosynthetic mechanism of cyclization is unknown and the discovery of novel sequences may assist in achieving this goal. In the present study, we have isolated a new cyclotide from Oldenlandia affinis, kalata B8, which appears to be a hybrid of the two major subfamilies (Mobius and bracelet) of currently known cyclotides. We have determined the three-dimensional structure of kalata B8 and observed broadening of resonances directly involved in the cystine knot motif, suggesting flexibility in this region despite it being the core structural element of the cyclotides. The cystine knot motif is widespread throughout Nature and inherently stable, making this apparent flexibility a surprising result. Further-more, there appears to be isomerization of the peptide backbone at an Asp-Gly sequence in the region involved in the cyclization process. Interestingly, such isomerization has been previously characterized in related cyclic knottins from Momordica cochinchinensis that have no sequence similarity to kalata B8 apart from the six conserved cysteine residues and may result from a common mechanism of cyclization. Kalata B8 also provides insight into the structure-activity relationships of cyclotides as it displays anti-HIV activity but lacks haemolytic activity. The 'uncoupling' of these two activities has not previously been observed for the cyclotides and may be related to the unusual hydrophilic nature of the peptide.