Efeito de reguladores vegetais no desenvolvimento de plantas jovens de Tabebuia avellanedae Lorentz ex Griseb

Tabebuia avellanedae Lorentz ex Griseb (ip��-roxo), Bignoniaceae, ocorre na Floresta Tropical Atl��ntica e �� de grande import��ncia, uma vez que, devido ��s suas propriedades medicinais e lenho de grande valor comercial, j�� esteve sob amea��a de extin����o. A mistura de reguladores vegetais �� conhecida como bioestimulante que pode incrementar o desenvolvimento vegetal, estimulando a divis��o, a diferencia����o e o alongamento celular. Assim, neste trabalho avaliou o efeito da aplica����o da mistura de reguladores vegetais do grupo das auxinas, giberelinas e citocininas no desenvolvimento de plantas jovens de ip��-roxo. Os tratamentos foram: testemunha, GA4+7 + BAP 100 mg L-1, GA4+7 + BAP 200 mg L-1, GA3 + IBA + cinetina 0,5% e GA3 + IBA + cinetina 1,0% os quais foram aplicados 4 vezes em intervalos de 30 dias. O efeito dos tratamentos foi avaliado pelas medidas de altura das plantas, di��metro do caule, n��mero de folhas, massa seca das folhas, caule e ra��zes e avalia����o de trocas gasosas. O tratamento com GA3 + BAP 200 mg L-1 foi aquele que apresentou maior efeito no crescimento das plantas. J�� para as avalia����es fotossint��ticas o tratamento com GA3 + IBA + cinetina foi aquele que apresentou a maior taxa de assimila����o de CO2

Magnetoterapia na cicatriza����o de feridas

Nowadays less invasive and ���toxic��� techniques are being searched, not only for the environment but also for the human and animal organisms themselves. So between the numerous studied and used techniques to help the tissue healing process there is the ���Magnet Therapy���. The aim of the present study was to

Influ��ncia do exerc��cio f��sico no remodelamento card��aco de ratos espontaneamente hipertensos

Coordena����o de Aperfei��oamento de Pessoal de N��vel Superior (CAPES)

Bidens pilosa L: efeitos protetores na inflama����o intestinal

Conselho Nacional de Desenvolvimento Cient��fico e Tecnol��gico (CNPq)

Avalia����o dos efeitos de aloe-emodin em c��lulas uroteliais imortalizadas e neopl��sicas cultivadas in vitro

Aloe vera (Aloe barbadensis Miller), popularly known in Brazil as babosa, has a long history of use as medicinal plant for different therapeutic purposes. The components of the plant extract are present in various products of human use, mainly for nutritional and cosmetics purposes. However, some studies suggest that this extract might also have carcinogenic activity. The aloe vera extract is a complex mixture of bioactive compounds. The study of isolated compounds may contribute to elucidate contradictory results about the effects related to the consumption of the plant, as well as their mechanisms of action. One of the most important compound from Aloe vera is aloe-emodin, which is a secondary metabolite generated in the intestinal tract. Putative antimicrobial and antitumor effects were previously attributed to aloe-emodin. Although the exposure of urothelial cells to aloe-emodin was already reported in the literature, only one study showed its effects on urothelial cells, suggesting that aloe-emodin inhibits the viability of T24 cancer cells due to apoptosis induction. Since there is no sufficient information about the effects of aloe-emodin on urothelial cells, and low efficiency in the treatment of bladder cancer currently, the present study aims to evaluate the hypothesis that the treatment with aloe-emodin could impact the behavior of other urothelial cell lines in vitro. Therefore, the in vitro IC50 exposure of aloe-emodin to human immortalized neoplastic urothelial cells will be determinated in order to verify possible differences in the behavior of urothelial cells in vitro treated with aloe-emodin in comparison with untreated cells. Furthermore, differences between cell lines will be also evaluated

A compreens��o das t��cnicas da equoterapia no campo da sa��de: uma perspectiva fenomenol��gica no campo da sa��de

P��s-gradua����o em Ci��ncias da Motricidade - IBRC

Perfil t��xico-farmacol��gico da administra����o da doxorrubicina em c��es com tumor ven��reo transmiss��vel

Funda����o de Amparo �� Pesquisa do Estado de S��o Paulo (FAPESP)

Avalia����o da a����o da melatonina em c��lulas-tronco tumorais mam��rias RE-positivas tratadas com disruptores estrog��nicos: verifica����o da via do receptor de estr��geno mediada pelo gene OCT 4

Conselho Nacional de Desenvolvimento Cient��fico e Tecnol��gico (CNPq)

A equoterapia como auxiliar no processo de inclus��o do aluno com defici��ncia visual: estudo de caso

This study examines the hippotherapy related to school inclusion. Inclusive education, given the diversity of human kind, seeks to understand and meet the educational needs of all students. Visual impairment is defined as a reduction or complete loss of ability to see with the better eye and after the best possible optical correction, and may be perceived by the focus when the individual educational needs of Braille for their learning. Hippotherapy is a therapeutic and educational method that uses the horse in an interdisciplinary approach in health, education and riding, searching for the biopsychosocial development of people with disabilities and/or special needs. The general objectives were: to follow a Hippotherapy program applied to a student with visual disabilities included in regular education from the practice sessions of hippotherapy and the student's school routine, and specific: to verify changes to a student with visual impairment during their participation in an equine therapy program, to check the commitment, involvement and interest in school activities the student practicing hippotherapy inserted into the regular school system. The methodology was a qualitative research, in the form of case study. The instruments of data collection were interviews, video recordings, photographs, school information and the subject of systematic observations of the sessions of hippotherapy. Interviews were conducted at three different times during the course of the program. First we used a strategy for succeeding in increasing the involvement of practicing with the school. Later, another strategy was established, consisting of the effective presence of the researcher in the school to carry out activities on the hippotherapy within the school environment. The analysis of the first interview showed no changes in school interest, however, occurred in the family environment. In analyzing the results of the second interview was seen as a...

Bioestimula����o de c��lula-tronco mesenquimal de rato sob a����o da luz cont��nua e puls��til de 630 nm utilizando LED

Funda����o de Amparo �� Pesquisa do Estado de S��o Paulo (FAPESP)

A equoterapia como auxiliar no processo de inclus��o do aluno com defici��ncia visual: estudo de caso

This study examines the hippotherapy related to school inclusion. Inclusive education, given the diversity of human kind, seeks to understand and meet the educational needs of all students. Visual impairment is defined as a reduction or complete loss of ability to see with the better eye and after the best possible optical correction, and may be perceived by the focus when the individual educational needs of Braille for their learning. Hippotherapy is a therapeutic and educational method that uses the horse in an interdisciplinary approach in health, education and riding, searching for the biopsychosocial development of people with disabilities and/or special needs. The general objectives were: to follow a Hippotherapy program applied to a student with visual disabilities included in regular education from the practice sessions of hippotherapy and the student's school routine, and specific: to verify changes to a student with visual impairment during their participation in an equine therapy program, to check the commitment, involvement and interest in school activities the student practicing hippotherapy inserted into the regular school system. The methodology was a qualitative research, in the form of case study. The instruments of data collection were interviews, video recordings, photographs, school information and the subject of systematic observations of the sessions of hippotherapy. Interviews were conducted at three different times during the course of the program. First we used a strategy for succeeding in increasing the involvement of practicing with the school. Later, another strategy was established, consisting of the effective presence of the researcher in the school to carry out activities on the hippotherapy within the school environment. The analysis of the first interview showed no changes in school interest, however, occurred in the family environment. In analyzing the results of the second interview was seen as a...

Bioestimula����o de c��lula-tronco mesenquimal de rato sob a����o da luz cont��nua e puls��til de 630 nm utilizando LED

Funda����o de Amparo �� Pesquisa do Estado de S��o Paulo (FAPESP)

Periocular basal cell carcinoma: cost of topical immunotherapy versus estimated cost of surgical treatment

Purpose: The objective of this study was to compare the estimated cost of clinical and surgical treatment for basl cell carcinoma of the eyelid. Methods: This was a pilot study of 12 patients with basal cell carcinoma receiving treatment with 5% imiquimod cream at the ocular plastic surgery center, medical school University of Sao Paulo (HC-FMUSP, Brazil). The cost of clinical treatment was estimated based on the time of treatment and amount of medication consumed by patients in the home setting. The cost of surgical treatment was estimated by ophthalmologists with experience in reconstructive plastic surgery based on analysis of images of the same patients. Surgeons responded to a questionnaire with four questions about surgical technique, surgical materials required, estimated duration of surgery and type of anesthesia. Results: Immunotherapy lasted from 8 to 12 weeks. All patients reported each cold-stored sachet with 5% imiquimod cream lasted 3 days. According to the institution, a box with 12 sachets costs BRL 480.00. Patients required 1.58-3.11 boxes for complete treatment, corresponding to a total cost of BRL 758.40-1,492.80. Based on image analysis, surgeons evaluated surgery would require 1-3 hours. The estimated cost of surgery room and staff was BRL 263.00, to which the cost of supplies was added. Thus, the total cost of surgical treatment was BRL 272.61-864.82. On the average, immunotherapy was 57,64% more costly than surgical treatment. Conclusions: Malignant eyelid tumors are a common finding in clinical ophthalmology. Surgery is still the treatment of choice at our institution, but immunotherapy with 5% imiquimod cream may be indicated for patients with multiple lesions or high surgical risk and for patients declining surgery for reasons of fear or esthetic concerns. The ability to estimate costs related to the treatment of malignant eyelid tumors is an important aid in the financial planning of health care institutions. Further studies should evaluate the possibility of institutions equating the cost of immunotherapy and surgical treatment by acquiring similar but less expensive medications.

Oral health as a predictive factor for oral mucositis

OBJECTIVES: Oral mucositis is a complication frequently associated with hematopoietic stem cell transplantation, decreasing a patient���s quality of life and increasing the occurrence of opportunistic infections. The purpose of this study was to determine the incidence and severity of oral mucositis and to assess the correlation of this disease with the oral health of an individual at the time of hematopoietic stem cell transplantation. METHODS: Before transplantation, patients��� oral health and inflammatory conditions were determined using the gingival index and the plaque index, which are based on gingival bleeding and the presence of dental plaque, respectively. Additionally, the dental health status was determined using the decayed, missing, and filled teeth index. The monitoring of oral mucositis was based on the World Health Organization grading system and was performed for five periods: from Day 0 to D+5, from D+6 to D+10, from D+11 to D+15, from D+16 to D+20, and from D+21 to D+30. RESULTS: A total of 97 patients (56% male and 44% female) who underwent hematopoietic stem cell transplantation at the Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo between January 2008 and July 2009 were prospectively examined. The incidence of ulcerative mucositis was highest from days +6 to +10 and from days +11 to +15 in the patients who underwent autologous and allogeneic hematopoietic stem cell transplantation, respectively. CONCLUSION: The data, including the dental plaque and periodontal status data, showed that these oral health factors were predictive of the incidence and severity of oral mucositis in a cohort of patients with similar conditioning regimens before hematopoietic stem cell transplantation

Defici��ncias ap��s a alta medicamentosa da hansen��ase: preval��ncia e distribui����o espacial

OBJETIVO: Estimar a frequ��ncia das defici��ncias f��sicas em pacientes tratados de hansen��ase ap��s alta medicamentosa e analisar sua distribui����o espacial. M��TODOS: Estudo descritivo transversal com 232 pessoas tratadas de hansen��ase de 1998 a 2006. As defici��ncias f��sicas foram avaliadas pelo Grau de Incapacidades da Organiza����o Mundial da Sa��de (GI/OMS) e pelo Eye-Hand-Foot (EHF). Os ex-pacientes foram geocodificados pelo endere��o de resid��ncia e os servi��os de reabilita����o pelo endere��o de sua sede. Foram apresentadas as frequ��ncias para o total e para os grupos grau 0, grau 1 e grau 2 do GI-OMS, considerando-se as vari��veis cl��nicas e sociodemogr��ficas na an��lise descritiva. Foram utilizados os testes t de Student, qui-quadrado (&#967;2) ou de Fisher, conforme apropriado, considerando-se significativos p < 0,05. RESULTADOS: Cerca de 51,6% era do sexo feminino, com m��dia de idade de 54 anos (dp15,7); 30,5% tinha menos de dois anos de educa����o formal; 43,5% trabalhava e 26,9% estava aposentado; a forma dimorfa predominou (39,9%). As defici��ncias avaliadas pelo GI-OMS e pelo EHF atingiram 32% dos ex-pacientes. A presen��a de defici��ncias foi maior com o aumento da idade (p = 0,029), em casos multibacilares (p = 0,005) e com julgamento ruim do paciente sobre sua sa��de f��sica (p < 0,001). Os que necessitavam de preven����o/reabilita����o percorreram dist��ncia m��dia de 5,5 km at�� o servi��o de reabilita����o. As pessoas com defici��ncia f��sica estavam distribu��das em todo o munic��pio, mas concentravam-se na ��rea mais populosa e de maior car��ncia socioecon��mica. CONCLUS��ES: A frequ��ncia de defici��ncias �� elevada ap��s a alta medicamentosa. Os ex-pacientes mais velhos, os que tiveram formas multibacilares da doen��a, os de baixa escolaridade e os que julgam mal a pr��pria sa��de f��sica merecem aten����o especial para a preven����o e reabilita����o de defici��ncias. A dist��ncia entre os servi��os de reabilita����o e as resid��ncias dos pacientes requer reorganiza����o da rede de atendimento no munic��pio.