Phosphorylation du CTD de l'ARN polymérase II et impact de l'histone H2A.Z sur le positionnement des nucléosomes chez S. cerevisiae

La phosphorylation du domaine C-terminal de l’ARN polymérase II permet à ce complexe protéique d’exécuter la transcription des gènes, en plus de coupler à la transcription des événements moléculaires comme la maturation des ARNm. Mes résultats montrent que même si cette phosphorylation suit un patron similaire à l’ensemble des gènes, il existe des exceptions pouvant être dues à des mécanismes alternatifs de phosphorylation du CTD. Le présent ouvrage s’intéresse également au rôle qu’occupe la variante d’histone H2A.Z dans l’organisation de la chromatine. Des études précédentes on montré que le positionnement de certains nucléosomes le long de l’ADN serait influencé par H2A.Z et aurait une influence sur la capacité de transcrire les gènes. Par une approche génomique utilisant les puces à ADN, j’ai cartographié l’impact de la délétion de H2A.Z sur la structure des nucléosomes. Enfin, des résultats intéressants sur la dynamique d’incorporation de H2A.Z à la chromatine ont été obtenus.

Recherches sur la plasticité du discours oraculaire: l'exemple de l'oracle du "Mur de bois" (Hérodote, 7, 140-146)

Ce mémoire vise à appliquer l’étude des oracles en Grèce au cas longtemps malmené de l’oracle du rempart de bois. Alors que les historiens modernes deviennent de plus en plus critiques face à la littérature oraculaire grâce aux découvertes de l’épigraphie, cet oracle semble résister à cette nouvelle vague : tout et son contraire ont été allégué afin de le préserver de l’étiquette de post eventum. À la lumière du cadre historique dans lequel Hérodote a conçu ses Histoires, nous serons en mesure de décortiquer les éléments constitutifs de cet oracle qui prédit l’issue de la Seconde Guerre médique et selon lequel les Athéniens trouvèrent leur salut derrière le désormais célèbre « rempart de bois ». Nous nous attarderons finalement au dit « Décret de Thémistocle », trouvé à Trézène et commandant l’évacuation d’Athènes. Au terme de ce mémoire, l’épisode du rempart de bois apparaîtra définitivement comme post eventum.

140 juegos de educación psicomotriz.

Resumen basado en el de la publicación

Customer service 140 characters at a time: the users’ perspective

Electronic word of mouth (eWoM) has been adopted by Internet users as a way of communicating their consumption preferences and experiences. Consumers are able to reach out to others, unknown to them, and have online conversations that can influence their behaviour. Organisations need to understand how to respond to these brand-related conversations conducted via social media. By looking through the lens of social capital, this paper contributes to social media and social capital research by studying the perceptions that 44 social media users have of companies that interact with them online. The users value social networks and support as part of their online relationships. However, several new value categories are identified when compared to previous research. Further research is required to investigate possible segmentation approaches and alternative methodological choices.

Explaining patterns of avian diversity and endemicity: climate and biomes of southern Africa over the last 140,000 years

Aim Test hypotheses that present biodiversity and endemic species richness are related to climatic stability and/or biome persistence.Location Africa south of 15° S. Methods Seventy eight HadCM3 general circulation model palaeoclimate experiments spanning the last 140,000 years, plus a pre-industrial experiment,were used to calculate measures of climatic variability for 0.5° grid cells. Models were fitted relating distributions of the nine biomes of South Africa,Lesotho and Swaziland to present climate. These models were used to simulate potential past biome distribution and extent for the 78 palaeoclimate experiments, and three measures of biome persistence. Climatic response surfaces were fitted for 690 bird species regularly breeding in the region and used to simulate present species richness for cells of the 0.5° grid. Species richness was evaluated for residents, mobile species (nomadic or partially/altitudinally migrant within the region), and intra-African migrants, and also separately for endemic/near-endemic (hereafter ‘endemic’) species as a whole and those associated with each biome. Our hypotheses were tested by analysing correlations between species richness and climatic variability or biome persistence. Results The magnitude of climatic variability showed clear spatial patterns. Marked changes in biome distributions and extents were projected, although limited areas of persistence were projected for some biomes. Overall species richness was not correlated with climatic variability, although richness of mobile species showed a weak negative correlation. Endemic species richness was significantly negatively correlated with climatic variability. Strongest correlations, however, were positive correlations between biome persistence and richness of endemics associated with individual biomes. Main conclusions Low climatic variability, and especially a degree of stability enabling biome persistence, is strongly correlated with species richness of birds endemic to southern Africa. This probably principally reflects reduced extinction risk for these species where the biome to which they are adapted persisted

A competência administrativa para o licenciamento ambiental na Lei Complementar nº 140/2011

O objetivo deste Trabalho de Conclusão de Curso é analisar as mudanças que Lei Complementar nº 140 de 2011 produziu na competência administrativa para licenciar. Analisei a definição da competência administrativa e o seu impacto na competência jurisdicional, incluindo uma análise da insegurança jurídica para os empreendedores durante a vigência da Resolução CONAMA nº 237/97, anterior à Lei Complementar nº 140. Para tanto, realizei pesquisa jurisprudencial sobre a constitucionalidade das disposições da referida Resolução, além de uma pesquisa jurisprudencial específica na tentativa de identificar o critério mais utilizado pelos Tribunais para identificação do órgão ambiental competente para licenciar. Explicitei as principais disposições da Lei Complementar, e finalizei o Trabalho com uma breve análise do que é possível esperar a partir de agora.

Decay resistance of thermally-modified Eucalyptus grandis wood at 140 degrees C, 160 degrees C, 180 degrees C, 200 degrees C and 220 degrees C

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Photon-induced multiple particle emissions of Zr90 and natZr from 10 to 140 MeV

A comprehensive analysis of electrodisintegration yields of protons on Zr90 is proposed taking into account the giant dipole resonance, isovector giant quadrupole resonance (IVGQR), and quasideuteron contributions to the total photoabsorption cross section from 10 to 140 MeV. The calculation applies the MCMC intranuclear cascade to address the direct and pre-equilibrium emissions and another Monte Carlo-based algorithm to describe the evaporation step. The final results of the total photoabsorption cross section for Zr90 and relevant decay channels are obtained by fitting the (e,p) measurements from the National Bureau of Standards and show that multiple proton emissions dominate the photonuclear reactions at higher energies. These results provide a consistent explanation for the exotic and steady increase of the (e,p) yield and also a strong evidence of a IVGQR with a strength parameter compatible with the E2 energy-weighted sum rule. The inclusive photoneutron cross sections for Zr90 and natZr, derived from these results and normalized with the (e,p) data, are in agreement within 10% with both Livermore and Saclay data up to 140 MeV. © 2007 The American Physical Society.

Interferência das plantas daninhas na nutrição e produtividade da cultura da berinjela cultivar 'Nápoli' com e sem tutoramento e desbrota

Pós-graduação em Agronomia (Produção Vegetal) - FCAV

York County Municipal Association Records - Accession 256 - M109 (140)

The York County Municipal Association Records consist of by-laws, correspondence, minutes, agenda notes and financial records of the organization whose principle objective is to develop the Association as an agency for the cooperation of the municipalities of York County.