The trouble with Dad.

Papá tiene un aburrido trabajo y en su tiempo libre se dedica a fabricar robots, para ayudar en casa, para cortar la hierba, para jugar al futbol. De tanto juquetear con ellos se hace famoso y un rico árabe le compra la colección para exhibirla en el desierto como objetos artísticos. Ahora, todos somos felices aunque por distintos motivos.

Nothing but trouble.

Para Maisie empieza el día con su hermano bebé despertándola bruscamente, luego su madre, distraída. derrama los cereales del desayuno en su cabeza y desde entonces las cosas van de mal en peor para ella, tanto en casa como en la escuela.

The trouble with elephants.

La historia comienza con la niña protagonista agarrada a su elefante de peluche. A ella le gustan los elefantes, pero gruñe por los inconvenientes que acarrea vivir con ellos. El elefante desborda el agua al meterse en la bañera y deja un redondel rosa en ella cuando sale, no pueden dormir ambos en la misma cama porque ella no tiene hueco, el escondite es muy difícil de jugar con ellos y así, muchos otros problemas que le plantean por su tamaño.

The trouble with maths : a practical guide to helping learners with numeracy difficulties.

Este manual ofrece importantes ideas sobre el mundo, a menudo confuso, de la aritmética elemental. Examina las dificultades de aprendizaje en matemáticas desde varias perspectivas, incluye el lenguaje de las matemáticas, estilos de pensamiento y las peticiones de cuestiones individuales. Tiene en cuenta todos los aspectos sobre matemáticas y aprendizaje, y ofrece asesoramiento, orientación y actividades prácticas, que permiten: desarrollar habilidades de pensamiento flexible; utilizar estrategias alternativas para los alumnos para acceder a datos básicos; implementar medidas preventivas eficaces antes de que se establezca el descontento; reconocer la ansiedad con las matemáticas y problemas de autoestima; realizar evaluaciones precisas de las dificultades de los alumnos; diseño informal de procedimientos de diagnóstico. Es un manual que puede proporcionar una visión general de dónde y cómo pueden surgir los problemas, que ofrece información sobre posibles dificultades, o centrarse en un problema particular y sugerir orientaciones que pueden ayudar a los alumnos a aprender.

Trouble on the Friendship Express?

The Maitreyi (Friendship) Express, the rail service between India and Bangladesh that was restarted recently evoked nostalgia and hopes for stronger ties between the two nations. However, it will take more than a rail link to deal with fears of infiltration by Bangladeshi Muslims that is being used in aggressive political rhetoric.

"HIT on Trousseau" double trouble: acquired coagulopathy with femoral artery thrombosis

Trousseau Syndrome is a paraneoplastic procoagulant phenomenon. Heparin-induced thrombocytopenia (HIT) is a rare complication of anticoagulation with heparin. To our knowledge, the coincidence of the two has not been reported so far. We report a case of an acute thrombosis of the left femoral artery and distal leg arteries in a patient with an otherwise normal cardiovascular status. Endovascular revascularization attempts using mechanical rotational thrombectomy catheter, aspiration and local thrombolysis were unsuccessful. Progressive coagulation along the intra-arterial catheter was seen. Surgical thrombectomy of the femoral-pedal axis was successful, but the patient developed an immune-mediated HIT postoperatively. An adenocarcinoma of the colon was the likely cause for the initial arterial thrombosis, and probably adversely affected endovascular revascularization attempts. Subsequent HIT with microvascular thrombosis worsened ischemic damage leading to a below knee-amputation, despite patent large vessels. Compared to venous thrombosis, arterial thrombosis is a rare manifestation of Trousseau syndrome. The coincidence of it with HIT is even rarer. There may be a causal relationship between the two.

The EU’s Trouble with Mashups: From Disabling to Enabling a Digital Art Form

New tools for editing of digital images, music and films have opened up new possibilities to enable wider circles of society to engage in ’artistic’ activities of different qualities. User-generated content has produced a plethora of new forms of artistic expression. One type of user-generated content is the mashup. Mashups are compositions that combine existing works (often) protected by copyright and transform them into new original creations. The European legislative framework has not yet reacted to the copyright problems provoked by mashups. Neither under the US fair use doctrine, nor under the strict corset of limitations and exceptions in Art 5 (2)-(3) of the Copyright Directive (2001/29/EC) have mashups found room to develop in a safe legal environment. The contribution analyzes the current European legal framework and identifies its insufficiencies with regard to enabling a legal mashup culture. By comparison with the US fair use approach, in particular the parody defense, a recent CJEU judgment serves as a comparative example. Finally, an attempt is made to suggest solutions for the European legislator, based on the policy proposals of the EU Commission’s “Digital Agenda” and more recent policy documents (e.g. “On Content in the Digital Market”, “Licenses for Europe”). In this context, a distinction is made between non-commercial mashup artists and the emerging commercial mashup scene.

WHEN DOES THE TROUBLE START? OBESITY, DIABETES RISKS AND METABOLIC DISTURBANCES IN YOUNG PEOPLE WITH PSYCHOSIS

People with psychotic disorders have higher mortality rates compared to the general population. Most deaths are due to cardiovascular (CV) disease, reflecting high rates of CV risk factors such as obesity and diabetes. Treatment with antipsychotic drugs is associated with weight gain in clinical trials. However, there is little information about how these drugs affect children and young people, and how early in the course of treatment the elevation in CV risk factors begins. This information is essential in understanding the costs and benefits of these treatments in young people, and establishing preventive and early intervention services to address physical health comorbidities. This symposium reports both prospective and naturalistic data from children and adolescents treated with antipsychotic drugs. These studies demonstrate that adverse effects on cardiometabolic measures, notably BMI and insulin resistance, become apparent very soon after treatment is initiated. Further, children and adolescents appear to be even more sensitive to these effects than adults. Population-wide studies are also informative. Danish data showing that young people exposed to antipsychotics have a higher risk of diabetes, compared with young people who had a psychiatric diagnosis but were not exposed to antipsychotic drugs, will be presented. In addition, an Australian comparison between a large, nationally representative sample of people with psychosis and a general population sample shows that higher rates of obesity and other cardiometabolic abnormalities are already evident in people with psychosis by the age of 25 years. Young people living with psychosis are already disadvantaged by the demands of living with mental illness, stigma, and social factors such as unemployment and low income. The addition of obesity, diabetes and other comorbidities adds a further burden. The data presented highlights the need for careful selection of antipsychotic drugs, regular monitoring of physical health and early intervention when weight gain, glucose dysregulation, or other cardiometabolic abnormalities are detected.