998 resultados para kuali ole
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Signatur des Originals: S 36/F00242
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Signatur des Originals: S 36/F08323
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Signatur des Originals: S 36/F08697
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Signatur des Originals: S 36/G02856
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Signatur des Originals: S 36/G02857
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Signatur des Originals: S 36/G02858
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Signatur des Originals: S 36/G02859
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Signatur des Originals: S 36/G03963
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Mode of access: Internet.
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a Marse Chan -- "Unc' Edinburg's drowndin'" -- Meh lady -- Ole 'Stracted -- "No Haid Pawn" -- Polly.
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Bound with the author's Ragionamento sulla lingua del testo misnico [Reggio, 1819]
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Nimiösivulla myös: Suomen kielelle käännetty herran Wiburin läänin maaherran ja riddarin Carl August Ramsayn waatimusten päälle.
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The `biomimetic` approach to tissue engineering usually involves the use of a bioreactor mimicking physiological parameters whilst supplying nutrients to the developing tissue. Here we present a new heart valve bioreactor, having as its centrepiece a ventricular assist device (VAD), which exposes the cell-scaffold constructs to a wider array of mechanical forces. The pump of the VAD has two chambers: a blood and a pneumatic chamber, separated by an elastic membrane. Pulsatile air-pressure is generated by a piston-type actuator and delivered to the pneumatic chamber, ejecting the fluid in the blood chamber. Subsequently, applied vacuum to the pneumatic chamber causes the blood chamber to fill. A mechanical heart valve was placed in the VAD`s inflow position. The tissue engineered (TE) valve was placed in the outflow position. The VAD was coupled in series with a Windkessel compliance chamber, variable throttle and reservoir, connected by silicone tubings. The reservoir sat on an elevated platform, allowing adjustment of ventricular preload between 0 and 11 mmHg. To allow for sterile gaseous exchange between the circuit interior and exterior, a 0.2 mu m filter was placed at the reservoir. Pressure and flow were registered downstream of the TE valve. The circuit was filled with culture medium and fitted in a standard 5% CO(2) incubator set at 37 degrees C. Pressure and flow waveforms were similar to those obtained under physiological conditions for the pulmonary circulation. The `cardiomimetic` approach presented here represents a new perspective to conventional biomimetic approaches in TE, with potential advantages. Copyright (C) 2010 John Wiley & Sons, Ltd.