Girl and Iguana

Mixed Media/Panel 24 x 24"

Late-onset posttraumatic septal hematoma and abscess formation in a six-year-old Tamil girl--case report and literature review

Nasal septal hematoma with abscess (NSHA) is an uncommon complication of trauma and studies on children are especially rare. We discuss the case of a 6-year-old girl, who was initially evaluated independently by three doctors for minor nasal trauma but had to be re-hospitalized 6 days later with NSHA. Although septal hematoma had initially been excluded (5, 7 and 24 hours after trauma), a secondary accumulation of blood seems to have occured. Delayed hematoma formation has been described in the orbit as a result of possible venous injuries after endoscopic sinus surgery. However, such an observation is new for septal hematoma in children. Thus, we recommend re-evaluation for septal hematoma 48h to 72h after paediatric nasal trauma. Such a scheduled re-examination offers a chance to treat delayed subperichondral hematoma on time before almost inevitable superinfection leads to abscess formation and destruction of the nasal infrastructure. We suggest that parents should be vigilant for delayed nasal obstruction as possible herald of hematoma accumulation within the first week.

Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene

CONTEXT: Thyroid transcription factor 1 (TITF1/NKX2.1) is expressed in the thyroid, lung, ventral forebrain, and pituitary. In the lung, TITF1/NKX2.1 activates the expression of genes critical for lung development and function. Titf/Nkx2.1(-/-) mice have pituitary and thyroid aplasia but also impairment of pulmonary branching. Humans with heterozygous TITF1/NKX2.1 mutations present with various combinations of primary hypothyroidism, respiratory distress, and neurological disorders. OBJECTIVE: The objective of the study was to report clinical and molecular studies of the first patient with lethal neonatal respiratory distress from a novel heterozygous TITF1/NKX2.1 mutation. Participant: This girl, the first child of healthy nonconsanguineous French-Canadian parents, was born at 41 wk. Birth weight was 3,460 g and Apgar scores were normal. Soon after birth, she developed acute respiratory failure with pulmonary hypertension. At neonatal screening on the second day of life, TSH was 31 mU/liter (N <15) and total T(4) 245 nmol/liter (N = 120-350). Despite mechanical ventilation, thyroxine, surfactant, and pulmonary vasodilators, the patient died on the 40th day. RESULTS: Histopathology revealed pulmonary tissue with low alveolar counts. The thyroid was normal. Sequencing of the patient's lymphocyte DNA revealed a novel heterozygous TITF1/NKX2.1 mutation (I207F). This mutation was not found in either parent. In vitro, the mutant TITF-1 had reduced DNA binding and transactivation capacity. CONCLUSION: This is the first reported case of a heterozygous TITF1/NKX2.1 mutation leading to neonatal death from respiratory failure. The association of severe unexplained respiratory distress in a term neonate with mild primary hypothyroidism is the clue that led to the diagnosis.

Just a Tea Stall Girl: Lessons from India

This article charts the learning of a female academic who travelled and volunteered in southern India during a sabbatical leave from her university. Opportunities to discover gender, race and class connections ranged from tea-stall conversations to academic symposia; from outings with impoverished Indian families to excursions with social justice organizations. The author explores topics that include dowry, politics, globalization, communalism, and poverty. To illustrate her learning, she draws on the work of such renowned Indian scholars as Ali Ashgar Engineer and Vandana Shiva.

Congenital aural atresia associated with agenesis of internal carotid artery in a girl with a FOXI3 deletion.

We report on the molecular characterization of a microdeletion of approximately 2.5 Mb at 2p11.2 in a female baby with left congenital aural atresia, microtia, and ipsilateral internal carotid artery agenesis. The deletion was characterized by fluorescence in situ hybridization, array comparative genomic hybridization, and whole genome re-sequencing. Among the genes present in the deleted region, we focused our attention on the FOXI3 gene. Foxi3 is a member of the Foxi class of Forkhead transcription factors. In mouse, chicken and zebrafish Foxi3 homologues are expressed in the ectoderm and endoderm giving rise to elements of the jaw as well as external, middle and inner ear. Homozygous Foxi3-/- mice have recently been generated and show a complete absence of the inner, middle, and external ears as well as severe defects in the jaw and palate. Recently, a 7-bp duplication within exon 1 of FOXI3 that produces a frameshift and a premature stop codon was found in hairless dogs. Mild malformations of the outer auditory canal (closed ear canal) and ear lobe have also been noted in a fraction of FOXI3 heterozygote Peruvian hairless dogs. Based on the phenotypes of Foxi3 mutant animals, we propose that FOXI3 may be responsible for the phenotypic features of our patient. Further characterization of the genomic region and the analysis of similar patients may help to demonstrate this point. © 2015 Wiley Periodicals, Inc.

Addresses to young children, originally delivered in the Girl's Free School, Bell Lane

[Charlotte v. Rothschild] [[Elektronische Ressource]]

Miss Yvonne Arnaud as "Suzanne" in "The girl in the taxi"

Signatur des Originals: S 36/F02611

"The girl in the taxi", Miss Yvonn Arnaud as "Suzanne" and Mr. Alec Fraser as "Réné"

Signatur des Originals: S 36/F02612

"The girl in the taxi.", Mr. C. H. Workman as "Pomarel" and Miss Yvonne Arnaud as "Suzanne"

Signatur des Originals: S 36/F02613

"The girl in the taxi.", Miss Yvonne Arnaud as "Suzanne", Messrs. Arthur Playfair as "Baron Dauvray", Alec Fraser as "Réné" and Robert Averell as "Hubert Dauvray"

Signatur des Originals: S 36/F02614

"The girl in the taxi.", Miss Yvonne Arnaud as "Suzanne"

Signatur des Originals: S 36/F02615

Margaret Paton als Jacqueline, Alec Fraser als Réné, Szenenfoto, in: Anthony Mars: The girl in the taxi

Signatur des Originals: S 36/F05689

Fanny Moody, Rollenbild, Kniestück, in: Michael William Balfe: The Bohemian Girl

Signatur des Originals: S 36/F09291

IPPF Girl Decide: Turning Decisions into realities

Turning Decisions into Realities: Girls Journeys The Girls Decide films share the stories of six girls from around the world in their journeys to make informed decisions about sex, pregnancy, abortion and relationships. The Girls Decide films share the stories of girls from around the world in their journeys to make informed choices about sex, pregnancy and relationships. www.ippf.org

"Scouts sin scoutismo" : Los artículos de Ángel M. Giménez y la posición de los socialistas argentinos frente a la institucionalización estatal del escautismo

Fil: Bisso, Andrés. Universidad Nacional de La Plata. Facultad de Humanidades y Ciencias de la Educación; Argentina.