Down-regulation of dendritic spine and glutamic acid decarboxylase 67 expressions in the reelin haploinsufficient heterozygous reeler mouse

Heterozygous reeler mice (HRM) haploinsufficient for reelin express ���50% of the brain reelin content of wild-type mice, but are phenotypically different from both wild-type mice and homozygous reeler mice. They exhibit, (i) a down-regulation of glutamic acid decarboxylase 67 (GAD67)-positive neurons in some but not every cortical layer of frontoparietal cortex (FPC), (ii) an increase of neuronal packing density and a decrease of cortical thickness because of neuropil hypoplasia, (iii) a decrease of dendritic spine expression density on basal and apical dendritic branches of motor FPC layer III pyramidal neurons, and (iv) a similar decrease in dendritic spines expressed on the basal dendrite branches of CA1 pyramidal neurons of the hippocampus. To establish whether the defect of GAD67 down-regulation observed in HRM is responsible for neuropil hypoplasia and decreased dendritic spine density, we studied heterozygous GAD67 knockout mice (HG67M). These mice exhibited a down-regulation of GAD67 mRNA expression in FPC (about 50%), but they expressed normal amounts of reelin and had no neuropil hypoplasia or down-regulation of dendritic spine expression. These findings, coupled with electron-microscopic observations that reelin colocalizes with integrin receptors on dendritic spines, suggest that reelin may be a factor in the dynamic expression of cortical dendritic spines perhaps by promoting integrin receptor clustering. These findings are interesting because the brain neurochemical and neuroanatomical phenotypic traits exhibited by the HRM are in several ways similar to those found in postmortem brains of psychotic patients.

Janet Sobel : expressions of experience

Historians have yet to realize the depth of artist Janet Sobel���s artistic aptitude and ingenuity. This paper focuses on understanding how unique Sobel and her art were due to her distinctive world experiences and her ability to express her feelings about these experiences through her art. It also demonstrates the importance of her Jewish and Ukrainian heritage, showing how this influenced her artistic development. Sobel immigrated to the United States at a young age and struggled with her identity. Her art was a way for her to define and accept her personal identity as an immigrant Eastern European Jew in America. In addition to this heritage, Sobel experienced many traumatic events in her early life. Her art therefore served as a way for Sobel to work through this past trauma and come to terms with it.

Modelling logical expressions exercises

Exercises of application of the systematic procedure to derive linear inequalities for logic expressions (Ejercicios de aplicaci��n del m��todo sistem��tico de obtenci��n de restricciones lineales para expresiones l��gicas).

Recognizing and tagging temporal expressions in Spanish

This paper shows a system about the recognition of temporal expressions in Spanish and the resolution of their temporal reference. For the identification and recognition of temporal expressions we have based on a temporal expression grammar and for the resolution on an inference engine, where we have the information necessary to do the date operation based on the recognized expressions. For further information treatment, the output is proposed by means of XML tags in order to add standard information of the resolution obtained. Different kinds of annotation of temporal expressions are explained in another articles [WILSON2001][KATZ2001]. In the evaluation of our proposal we have obtained successful results.

Grammar specification for the recognition of temporal expressions

This paper tells about the recognition of temporal expressions and the resolution of their temporal reference. A proposal of the units we have used to face up this tasks over a restricted domain is shown. We work with newspapers' articles in Spanish, that is why every reference we use is in Spanish. For the identification and recognition of temporal expressions we base on a temporal expression grammar and for the resolution on a dictionary, where we have the information necessary to do the date operation based on the recognized expressions. In the evaluation of our proposal we have obtained successful results for the examples studied.

Applying semantic knowledge to the automatic processing of temporal expressions and events in natural language

This paper addresses the problem of the automatic recognition and classification of temporal expressions and events in human language. Efficacy in these tasks is crucial if the broader task of temporal information processing is to be successfully performed. We analyze whether the application of semantic knowledge to these tasks improves the performance of current approaches. We therefore present and evaluate a data-driven approach as part of a system: TIPSem. Our approach uses lexical semantics and semantic roles as additional information to extend classical approaches which are principally based on morphosyntax. The results obtained for English show that semantic knowledge aids in temporal expression and event recognition, achieving an error reduction of 59% and 21%, while in classification the contribution is limited. From the analysis of the results it may be concluded that the application of semantic knowledge leads to more general models and aids in the recognition of temporal entities that are ambiguous at shallower language analysis levels. We also discovered that lexical semantics and semantic roles have complementary advantages, and that it is useful to combine them. Finally, we carried out the same analysis for Spanish. The results obtained show comparable advantages. This supports the hypothesis that applying the proposed semantic knowledge may be useful for different languages.

Detecting implicit expressions of affect in text using EmotiNet and its extensions

In the past years, an important volume of research in Natural Language Processing has concentrated on the development of automatic systems to deal with affect in text. The different approaches considered dealt mostly with explicit expressions of emotion, at word level. Nevertheless, expressions of emotion are often implicit, inferrable from situations that have an affective meaning. Dealing with this phenomenon requires automatic systems to have ���knowledge��� on the situation, and the concepts it describes and their interaction, to be able to ���judge��� it, in the same manner as a person would. This necessity motivated us to develop the EmotiNet knowledge base ��� a resource for the detection of emotion from text based on commonsense knowledge on concepts, their interaction and their affective consequence. In this article, we briefly present the process undergone to build EmotiNet and subsequently propose methods to extend the knowledge it contains. We further on analyse the performance of implicit affect detection using this resource. We compare the results obtained with EmotiNet to the use of alternative methods for affect detection. Following the evaluations, we conclude that the structure and content of EmotiNet are appropriate to address the automatic treatment of implicitly expressed affect, that the knowledge it contains can be easily extended and that overall, methods employing EmotiNet obtain better results than traditional emotion detection approaches.

Transportation expressions.

Transportation Department, Bureau of Transportation Statistics, Washington, D.C.

An approach to the compilation of array expressions in the OL/2 language.

Originally presented as the author's thesis, University of Illinois at Urbana-Champaign.

An algorithm for evaluating array expressions in OL/2 /

"January, 1971."

Quadratic algorithms for minimizing joins in restricted relational expressions /

"October 1979."

A dictionary of English synonymes and synonymous or parallel expressions : designed as a practical guide to aptness and variety of phraseology /

Mode of access: Internet.

Nouveau dictionnaire du voyageur : fran��ois-allemand-latin, et allemand-fran��ois-latin : enrichi de tous les mots, et de toutes les expressions fran��oises, & allemandes nouvellement introduites ...

Mode of access: Internet.

Par��miologie musicale de la langue fran��aise : ou Explication des proverbes, locutions proverbiales, mots figur��s, qui tirent leur origine de la musique, accompagn��e de recherches sur un grand nombre d'expressions du m��me genre emprunt��es aux langues ��trang��res, et suivi de La Saint-Julien des m��n��triers, symphonie-cantata �� grand orchestre, avec solos et choeurs /

"Table alphab��tique des principaux termes employ��s dans les proverbes musicaux, de leurs cong��n��res, de leurs fr��quentatifs et de leurs d��riv��s pris au propre ou au figure": p. [665]-677.