No les enchufe a la tele : ud. decide dónde, cuándo, cuánto y cómo ve la caja tonta.

Se dan algunas sugerencias, destinadas a los padres, para promover prácticas televisivas adecuadas entre los niños. Entre otras pautas se indica lo siguiente, evitar que los pequeños vean solos la televisión, control del tiempo de visionado, utilización de la televisión como recurso educativo, seleccionar la programación y evitar usar la televisión como premio o castigo.

No corras, ve despacio...

El hombre se pregunta sobre su mismo ser, cuestiona todo y cada uno de los acontecimientos que se suceden y valora esos acontecimientos. ¿Qué significa vivir? ¿A dónde me lleva la vida? ¿Qué sentido tiene? Hay que exigirle un sentido porque lo tiene. Esas preguntas nos obligan a estar en vilo a buscar respuesta a vida, muerte, lucha, ilusión de alguna manera las cuestiones que nos planteamos no tienen solución o no tienen respuesta. Y, sin embargo, esto es necesario para seguir. Como se dice siempre, de la duda, de la visión crítica, de los intentos de solución y de las distintas respuesta, pero son necesarias para seguir. Como se dice siempre de la duda, de la visión crítica, de los intentos de solución, y de las distintas respuestas que el hombre va dando a todas las cuestiones que el surgen, vamos evolucionando, en cultura, ciencia. Si trasladamos esto a la existencia, a la vida humana, sucederá igual el primer paso, a la vida humana, sucederá igual: el primer paso para una respuesta es la duda, es la pregunta.

El valor formativo y las ataduras de las creencias en la formación del profesorado : aquello que no se ve, pero se percibe en el aula.

Monográfico con el título: Perfiles y escenarios de la educación. Resumen tomado de la publicación

Lo que el ojo no ve : un estudio de caso basado en procesos de indagación co(wiki)laborativos.

Resumen basado en el de la publicación

Identi???cation of degrees of anxiety in children with three- and ???ve-face facial scales

Resumen tomado de la publicaci??n

Mirar els ve??ns : actualitat (i necessitat) de la pedagogia comparada

Diversos informes internacionales sobre los sistemas educativos han tenido repercusi??n medi??tica, producto de la exigencia de la sociedad de ajustar cuentas con el sistema escolar y con la uniformizaci??n de los sistemas nacionales. Los an??lisis y valoraciones que se muestran en el libro que se recomienda y que suscita estas reflexiones, coordinado por los profesores Joaqu??n Prats y Francesc Ravent??s, de la Universidad de Barcelona, entroncan con una tradici??n que viene de lejos para conocer qu?? se hace en otros lugares, en base a la pedagog??a comparada.

La f??sica que ve del cel

Resumen basado en el de la publicaci??n

Coure, el veí del costat

Una línia de recerca de la UdG persegueix la substitució del pal·ladi pel coure com a catalitzador d’importants reaccions químiques. La menor toxicitat i el cost també menor del coure mouen els investigadors

A Comparati ve Study of Mechanical and Tribological Properties of AISI-304 and AISI-316 Submitted to Glow Discharge Nitriding

Mechanical and tribological properties of AISI 304 and AISI 316 stainless steels submitted to glow discharge ion nitriding are reported. The atmosphere was 20:80 - N2:H2 with substrate temperatures ranging from 300 to 500 °C. Treatment at 300 °C produced expanded austenite (γN) in both steels. Increasing the temperature, the phases γ′-Fe4N and ε- Fe2+xN were present and the latter is the major phase for AISI 304. At 500 °C, the CrN phase was also identified in both steels. Hardnesses of about 13-14 GPa at near surface regions were obtained in both steels. Moreover, AISI 316 nitrided at 500 °C has the deepest hard layer. Tribological tests showed that wear can be reduced by up to a factor of six after the nitriding processes, even for a working temperature of 300 °C. The profiles during and after nanoscratch tests did not reveal significant differences after nitriding processes in both steels.

Aberrant expression of E-cadherin and beta-catenin proteins in placenta of bovine embryos derived from somatic cell nuclear transfer

Abnormal placental development is common in the bovine somatic cell nuclear transfer (SCNT)-derived fetus. In the present study, we characterised the expression of E-cadherin and beta-catenin, structural proteins of adherens junctions, in SCNT gestations as a model for impaired placentation. Cotyledonary tissues were separated from pregnant uteri of SCNT (n - 6) and control pregnancies (n - 8) obtained by artificial insemination. Samples were analysed by western blot, quantitative RT-PCR (qRT-PCR) and immunohistochemistry. Bovine trophectoderm cell lines derived from SCNT and control embryos were analysed to compare with the in utero condition. Although no differences in E-cadherin or beta-catenin mRNA abundance were observed in fetal tissues between the two groups, proteins encoded by these genes were markedly under-expressed in SCNT trophoblast cells. Immunohistochemistry revealed a different pattern of E-cadherin and total beta-catenin localisation in SCNT placentas compared with controls. No difference was observed in subcellular localisation of dephosphorylated active-beta-catenin protein in SCNT tissues compared with controls. However, qRT-PCR confirmed that the wingless (WNT)/beta-catenin signalling pathway target genes CCND1, CLDN1 and MSX1 were downregulated in SCNT placentas. No differences were detected between two groups of bovine trophectoderm cell lines. Our results suggest that impaired expression of E-cadherin and beta-catenin proteins, along with defective beta-catenin signalling during embryo attachment, specifically during placentation, is a molecular mechanism explaining insufficient placentation in the bovine SCNT-derived fetus.

CDHI promoter hypermethylation and E-cadherin protein expression in infiltrating breast cancer

Background: the E-cadherin gene (CDH1) maps, at chromosome 16q22.1, a region often associated with loss of heterozygosity (LOH) in human breast cancer. LOH at this site is thought to lead to loss of function of this tumor suppressor gene and was correlated with decreased disease-free survival, poor prognosis, and metastasis. Differential CpG island methylation in the promoter region of the CDH1 gene might be an alternative way for the loss of expression and function of E-cadherin, leading to loss of tissue integrity, an essential step in tumor progression.Methods: the aim of our study was to assess, by Methylation-Specific Polymerase Chain Reaction (MSP), the methylation pattern of the CDH1 gene and its possible correlation with the expression of E-cadherin and other standard immunohistochemical parameters (Her-2, ER, PgR, p53, and K-67) in a series of 79 primary breast cancers ( 71 infiltrating ductal, 5 infiltrating lobular, 1 metaplastic, 1 apocrine, and 1 papillary carcinoma).Results: CDH1 hypermethylation was observed in 72% of the cases including 52/71 ductal, 4/5 lobular carcinomas and 1 apocrine carcinoma. Reduced levels of E-cadherin protein were observed in 85% of our samples. Although not statistically significant, the levels of E-cadherin expression tended to diminish with the CDH1 promoter region methylation. In the group of 71 ductal cancinomas, most of the cases of showing CDH1 hypermethylation also presented reduced levels of expression of ER and PgR proteins, and a possible association was observed between CDH1 methylation and ER expression ( p = 0.0301, Fisher's exact test). However, this finding was not considered significant after Bonferroni correction of p-value.Conclusion: Our preliminary findings suggested that abnormal CDH1 methylation occurs in high frequencies in infiltrating breast cancers associated with a decrease in E-cadherin expression in a subgroup of cases characterized by loss of expression of other important genes to the mammary carcinogenesis process, probably due to the disruption of the mechanism of maintenance of DNA methylation in tumoral cells.