194 resultados para Scars


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Dolostones of the upper Piaui Formation, Parnaiba Basin, northern Brazil, preserve a rich and diversified invertebrate fauna of Morrowan to Desmoinesian age. Among bivalves, Heteroconchia (15 species) is the most diversified, followed by Pteriomorphia (11 species), and rare endobenthic species of the Palaeotaxodonta. (three species). Eleven species of Pteriomorphia are described, including representatives of the genera Parallelodon?, Myalina?, Septimyalina, Caneyella?, Leptodesma (Leptodesma), L. (Leiopteria), Meekopinna?, Aviculopinna?, and Aviculopecten. A new combination, Etheripecten trichotomus, and the oldest member of the Anomiidae recorded, Pindorama nordestina n. gen. and sp., also are described. Details of muscle scars and hinge characters have been recovered for several taxa, thereby refining the knowledge for species diagnoses. Fossil beds in the Esperanca and Mucambo dolostones reveal episodic burial of bivalves in life position. These are internally complex, multistory fossil concentrations recording background and episodic processes. Hence, those fossil concentrations show high degrees of time-averaging and poor palcoecological resolution (except for the bivalves preserved in situ).

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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In this study, the occurrence of Othonella araguaiana Mendes, a rare bivalve species is reported for the first time in the Pinzonella illusa biozone, Middle Permian Corumbatai Formation, in the State of São Paulo. This species was originally described in coeval rocks of the Estrada Nova Formation (= Corumbatai) from the Alto Araguaia and Alto Garcas regions, State of Mato Grosso. The specimens of O. araguaiana were found in the base of a bioclastic sandstone bed, a proximal tempestite, in the middle of the Corumbatai Formation, in the city of Rio Claro, São Paulo State. The silicified shells and internal molds are well preserved, showing impressions of muscle scars and other internal anatomic characters (e.g., hinge), never illustrated by previous authors. In his original description, Mendes (1963) called attention to the similarity between O. araguaiana and Terraia aequilateralis, a common veneroid of the Corumbatai Formation. Conversely, Runnegar and Newell (1971) suggested that O. araguaiana belongs to Megadesmidae, being a junior synonym of Plesiocyprinella carinata (the commonest megadesmid of the Passa Dois Group). Our study indicates that O. araguaiana is indeed a megadesmid, but is distinct from the P. carinata. The new occurrence of O. araguaiana demonstrates that a) the paleobiogeographic distribution of this species is wider than previously thought (that it was restricted to the northern part of Parana Basin, Mato Grosso State); b) the molluscan fauna of the Corumbatai Formation (P. illusa biozone) in the State of São Paulo is more diverse and dominated by megadesmids; and c) the composition of the molluscan fauna of the Corumbatai Formation in Alto GarYas, State of Mato Grosso, is essentially the same as that of the P. illusa biozone of the eastern margin of the Parana Basin.

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Juvenile cellulitis or juvenile sterile granulomatous lymphadenitis is a rare disorder that affects puppies between three weeks to six months years old. Clinical signs include alopecia, edema, papules, pustules and crusts especially on eyelids. Definitive diagnosis requires cytological and histological evaluation and early and aggressive therapy is recommended, once scars after recovery can be severe. The choice treatment is the high dose of corticosteroids use such as prednisone. Three animals of canine species were attended at the Veterinary Hospital Clinical Small Animal Service presenting different clinical signs. Hemogram, skin lesions and submandibular lymph nodes cytological examination was collected and analyzed. The treatment was instituted, using cephalexin (22mg/kg, twice daily) up to control of secondary bacterial infection, and prednisone (2mg/kg, once a day) until clinical resolution. Complete cure was obtained at the end of treatment. The aim of this work is to report three clinical cases of juvenile cellulitis in dogs.

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Objective: We evaluated clinical characteristics of primary vesicoureteral reflux (VLJR) in infants in a 30-year period in Brazil with special reference to the relation of renal parenchymal damage to urinary tract infection and gender. Materials and Methods: From 1975 through 2005, 417 girls (81.6%) and 94 boys (18.4%) with all grades of reflux were retrospectively reviewed. Patients were categorized by the worst grade of reflux, maintained on antibiotic prophylaxis and underwent yearly voiding cystourethrography until the reflux was resolved. VUR was considered resolved when a follow-up cystogram demonstrated no reflux. Surgical correction was recommended for those who fail medical therapy, severe renal scarring or persistent VUR. Results: Grades I to V VUR resolved in 87.5%, 77.6%, 52.8%, 12.2% and 4.3%, respectively. Renal scars were present at presentation in 98 patients (19.2%). Neither gender nor bilaterality versus unilaterality was a helpful predictor of resolution. The significant difference was found among the curves using the log rank (p < 0.001) or Wilcoxon (p < 0.001) test. Conclusion: Despite the current use of screening prenatal ultrasound, many infants are still diagnosed as having vesicoureteral reflux only after the occurrence of urinary tract infection in our country. Scarring may be associated to any reflux grade and it may be initially diagnosed at any age but half of the scars are noted with higher grades of reflux (IV and V). The incidence of reflux related morbidity in children has significantly diminished over the last three decades.

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The city of Cubatão is a densely populated area with high industrial activity. In the area there are also important linear works as roads, railways, pipelines, aqueducts and lines of transmission of energy. The geological and geomorphological features of the municipality, combined with the human activities, make the site an area heavily prone to the landslides, so a region at high risk. In this work, landslide scars were extracted in aerial photos from 1985 and 1994, years that recorded a high incidence of landslides. Quantitative analysis of the relationship between the occurrence of scars and the forms of tracks were conducted, based on an intensive survey of scars in the region, represented by 2595 extracted scars, with the aim of contributing to a better understanding of the slipping processes in the Serra do Mar paulista and thus to the reduction of risks in the region. Achievements have concluded that the greatest percentage of slides in the region is linked to the strands straitght, followed by convex, which confirms previous studies conducted in the region, in a qualitative way or with a much lower number of scars.

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During a recent inspection in the Paleontological Collection of the Institute of Geosciences, University of São Paulo, we have identifi ed some specimens of undescribed mollusk bivalves. These called our attention for the following reasons: a) all specimens are internal molds of conjugated and closed articulated valves, some of them presenting fragments of silicifi ed shells; b) all internal molds have similar general shape and internal characters, representing specimens of the same taxon; c) the internal molds and silicifi ed valves are well preserved, including fragile structures, which are hardly preserved, such as the internal mold of the external ligament and muscle scars; d) and equally important, according to the labels of all specimens, they were collected from rocks of the Passa Dois Group (Permian), Serrinha Member of the Rio do Rasto Formation. Although who collected the shells and the precise geographic location of the specimens are still unknown, the detailed study of these fossils brings us to the conclusion that they are morphologically distinct from any heretofore published genus of the endemic fauna of bivalves from Passa Dois Group. Based in its general shape, hinge structure and muscles scars, the new form can be classifi ed under the Family Megadesmidae Vokes, 1967, the most diverse group of Permian bivalves of the Paraná Basin. The specimens are referred as Beurlenella elongatella new gen. and sp. The shell shape and taphonomy indicate that this bivalve was a shallow, rapid, active burrower, suspension feeder, probably preserved in situ, in event deposits.

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In this study, the occurrence of Othonella araguaiana Mendes, a rare bivalve species is reported for the fi rst time in the Pinzonella illusa biozone, Middle Permian Corumbataí Formation, in the State of São Paulo. This species was originally described in coeval rocks of the Estrada Nova Formation (= Corumbataí) from the Alto Araguaia and Alto Garças regions, State of Mato Grosso. The specimens of O. araguaiana were found in the base of a bioclastic sandstone bed, a proximal tempestite, in the middle of the Corumbataí Formation, in the city of Rio Claro, São Paulo State. The silicifi ed shells and internal molds are well preserved, showing impressions of muscle scars and other internal anatomic characters (e.g., hinge), never illustrated by previous authors. In his original description, Mendes (1963) called attention to the similarity between O. araguaiana and Terraia aequilateralis, a common veneroid of the Corumbataí Formation. Conversely, Runnegar and Newell (1971) suggested that O. araguaiana belongs to Megadesmidae, being a junior synonym of Plesiocyprinella carinata (the commonest megadesmid of the Passa Dois Group). Our study indicates that O. araguaiana is indeed a megadesmid, but is distinct from the P. carinata. The new occurrence of O. araguaiana demonstrates that a) the paleobiogeographic distribution of this species is wider than previously thought (that it was restricted to the northern part of Paraná Basin, Mato Grosso State); b) the molluscan fauna of the Corumbataí Formation (P. illusa biozone) in the State of São Paulo is more diverse and dominated by megadesmids; and c) the composition of the molluscan fauna of the Corumbataí Formation in Alto Garças, State of Mato Grosso, is essentially the same as that of the P. illusa biozone of the eastern margin of the Paraná Basin.

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Clinical, histopathological and ultrastructural findings of caprine dystrophic epidermolysis bullosa (DEB) with autosomal recessive inheritance are reported. The goats presented with exungulation, erosions, crusts and scars on the skin and ulcers in the oral cavity. Microscopically, the skin showed subepidermal separation with clefts filled occasionally with clear eosinophilic fluid, cellular debris or neutrophils. Ultrastructurally, the site of blister formation was the sublamina densa in the epidermal basement membrane zone. In skin with blister formation and in clinically uninvolved skin, the basal lamina was preserved, but the anchoring fibrils were sparse and rudimentary. A twin brother of an affected kid was mated over 5 years with his mother; three out of the 10 kids born presented with epidermolysis bullosa, indicating that the disease has an autosomal recessive mode of inheritance. It is suggested that the disease is similar to human severe generalized recessive DEB. © 2012 Elsevier Ltd.

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Two Quarter Horse mares with hereditary equine regional dermal asthenia (HERDA) were diagnosed with metastatic squamous cell carcinoma (SCC) associated with chronic nonhealing wounds. The lesions were similar to the development of SCC from chronic nonhealing ulcers, known as Marjolin's ulcers in humans. The horses showed recurrent skin wounds in the saddle and paralumbar regions and were confirmed by molecular techniques as having HERDA. Both horses were maintained as research animals for prolonged periods and received regular veterinary care and wound treatment. Both horses were ultimately euthanized because of their chronic progressive wounds, coupled with declining health. At necropsy, the nonhealing wounds were found to be complicated by infiltrative SCC; both horses had metastasis to lungs. Chronically inflamed, recurrent skin wounds that heal slowly and incompletely as a consequence of HERDA are proposed as a major pathogenetic factor in tumorigenesis. Consistent findings with respect to proliferation index (Ki-67) and mutations of p53 tumor suppressor gene were confirmed by immunohistochemistry in one horse. SCC consistent with Marjolin's ulcer has been previously suggested in association with chronic ulcers or burn scars in horses, but this is the first report of an association with chronic poor healing wounds in HERDA horses. © 2013 Elsevier Inc.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Bases Gerais da Cirurgia - FMB

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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A infecção do trato urinário (ITU) é uma das doenças mais comuns na infância e em 80 a 90% dos casos é causada por bactérias da família Enterobacteriaceae, especialmente Escherichia coli e Klebsiella pneumoniae, as quais no mundo inteiro têm emergido como produtoras de ESBL, um dos principais mecanismos de resistência bacteriana a cefalosporinas de espectro-estendido e monobactans. A prevalência da ITU em crianças, bem como as variáveis, sexo, idade, febre, bactéria mais frequente, presença de refluxo vesico-ureteral (RVU), presença de cicatrizes renais foram avaliadas no período de janeiro de 2006 a março de 2009, em hospital público de belém, região norte do Brasil e no período de abril a agosto de 2009, isolados de cepas de E. coli e K. pneumoniae foram obtidos de urina de crianças menores de 16 anos e avaliados fenotipicamente através do método automatizado de caracterização de ESBL, Vitek2, juntamente com a PCR para determinar se os genes blaTEM, blaSHV e blaCTX-M1 estavam presentes em cada organismo. Foram confirmados 199 casos de ITU no período estudado, 54,2% eram do sexo feminino, 46,2% eram menores de 02 anos de idade, febre ocorreu em 37,3% dos casos, RVU foi identificado em 38,6% das crianças com ITU e cicatriz renal em 38%, a bactéria mais frequente foi a E. coli (60%). Foram isoladas 43 amostras ( E. coli e K. pneumoniae, 74,4% e 25,6%, respectivamente), 95% foi resistente a ampicilina e sulfametoxazol-trimetroprim; 23,2% apresentaram fenótipo ESBL. O gene blaCTX-M1 foi o mais prevalente, encontrado em 19 cepas, seguido do gene blaTEM (18 cepas) e blaSHV (8 cepas). Esse estudo mostrou que bactérias com perfil de resistência ESBLcirculam no ambiente hospitalar em Belém e que os genes blaCTX-M1 e blaTEM e blaSHV estão presentes em cepas de E. coli e K. pneumoniae causadoras de ITU em crianças na região norte do Brasil.

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As florestas tropicais da Amazônia historicamente foram alvo de práticas pouco sustentáveis de uso da terra, restando-lhes as cicatrizes de degradação advinda da exploração madeireira predatória, do uso indiscriminado do fogo, das altas taxas de desmatamento e de outras atividades que interferem nas ações de conservação da biodiversidade desta floresta. A atuação do Estado neste cenário é necessária através de políticas que incentivem formas de uso mais sustentáveis, como é o caso das concessões florestais que buscam através do manejo florestal, contribuir para a conservação dos recursos naturais e da manutenção da biodiversidade. A geração de produtos como o Índice de Vegetação por Diferença Normalizada, Modelo Linear de Mistura Espectral e Fração de Abertura de Dossel foram realizados no intuito de criar elementos de interpretação e análise da variável abertura de dossel. Esta pesquisa teve como área de estudo a Unidade de Manejo Florestal I no Conjunto de Glebas Mamuru-Arapiuns, região oeste do estado do Pará; onde foram quantificados e avaliados a abertura de dossel nessa área de concessão florestal, através de imagens multiespectrais e fotos hemisféricas, com vistas a analisar a degradação e a qualidade do manejo executado nesta área. Os resultados obtidos mostraram que é possível estabelecer um processo de monitoramento com o uso dos sensores e técnicas aplicados, uma vez que os dados de MLME, em especial a imagem-fração solo apresentaram forte relação de covariância com os dados obtidos em campo através de fotos hemisféricas, permitindo considera-lo como uma boa ferramenta de alerta para as ações de monitoramentos das florestas amazônicas. Desta forma é possível tornar a gestão florestal mais acessível tanto ao poder público, quanto a entidades não governamentais ou privadas visando fiscalizar as ações de exploração florestal e agregar as populações que vivem nestas áreas tanto oportunidades de renda quanto a conservação florestal.