Modelos no lineales para describir el crecimiento de bufalinos de la raza Murrah

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Uso de probióticos em ração de rã-touro (Rana catesbeiana): Desempenho produtivo

This experiment had as objective to evaluate the effect of two probiotics, added in the commercial ration (40% PB) on the productive performance of bullfrog Rana catesbeiana. The test was lead with two dosages of each probiotic (5 g/kg of food and 10 g/kg of food), plus a control group, with three repetitions, totalizing five treatments. The weight gain, the feed conversion (CA) and the specific growth rate (TCE) have been analyzed. The results show that the probiotics affect the weight gain of Rana catesbeiana until reaching 200 g, thus decreasing the time of productivity in 28 days but not improving the CA and the TCE. With bases in these experimental conditions probiotic 1 (Lactobacillus acidofillus, Bifidobacterium bifidum and Enterococcus faecium -3×10 6 UFC/g) at lower dose (5 g/kg of ration) provided the best performance of the animals.

Development of a natural products database from the biodiversity of Brazil

We describe herein the design and development of an innovative tool called the NuBBE database (NuBBEDB), a new Web-based database, which incorporates several classes of secondary metabolites and derivatives from the biodiversity of Brazil. This natural product database incorporates botanical, chemical, pharmacological, and toxicological compound information. The NuBBEDB provides specialized information to the worldwide scientific community and can serve as a useful tool for studies on the multidisciplinary interfaces related to chemistry and biology, including virtual screening, dereplication, metabolomics, and medicinal chemistry. The NuBBEDB site is at http://nubbe.iq.unesp.br/nubbeDB.html. © 2013 The American Chemical Society and American Society of Pharmacognosy.

MATIW 1451 - monitoramento e acionamento de transdutores inteligentes através da Web (Padrão IEEE 1451)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

DiffServer: Application Level Differentiated Services for Web Servers

Web content hosting, in which a Web server stores and provides Web access to documents for different customers, is becoming increasingly common. For example, a web server can host webpages for several different companies and individuals. Traditionally, Web Service Providers (WSPs) provide all customers with the same level of performance (best-effort service). Most service differentiation has been in the pricing structure (individual vs. business rates) or the connectivity type (dial-up access vs. leased line, etc.). This report presents DiffServer, a program that implements two simple, server-side, application-level mechanisms (server-centric and client-centric) to provide different levels of web service. The results of the experiments show that there is not much overhead due to the addition of this additional layer of abstraction between the client and the Apache web server under light load conditions. Also, the average waiting time for high priority requests decreases significantly after they are assigned priorities as compared to a FIFO approach.

Simcluster: clustering enumeration gene expression data on the simplex space

Abstract Background Transcript enumeration methods such as SAGE, MPSS, and sequencing-by-synthesis EST "digital northern", are important high-throughput techniques for digital gene expression measurement. As other counting or voting processes, these measurements constitute compositional data exhibiting properties particular to the simplex space where the summation of the components is constrained. These properties are not present on regular Euclidean spaces, on which hybridization-based microarray data is often modeled. Therefore, pattern recognition methods commonly used for microarray data analysis may be non-informative for the data generated by transcript enumeration techniques since they ignore certain fundamental properties of this space. Results Here we present a software tool, Simcluster, designed to perform clustering analysis for data on the simplex space. We present Simcluster as a stand-alone command-line C package and as a user-friendly on-line tool. Both versions are available at: http://xerad.systemsbiology.net/simcluster. Conclusion Simcluster is designed in accordance with a well-established mathematical framework for compositional data analysis, which provides principled procedures for dealing with the simplex space, and is thus applicable in a number of contexts, including enumeration-based gene expression data.

Gestor web de recursos geoespaciales con tecnología Openlayers

[ES] El objetivo de este Trabajo Final de Grado (TFG) es la creación de un prototipo de aplicación web para la gestión de recursos geoespaciales. Esta propuesta surgió a partir de la necesidad de disponer de una herramienta que no tuviera que ser instalada en un dispositivo, sino servida por un servidor web, permitiendo su acceso desde cualquier parte y dispositivo. El resultado fue el Gestor Web de Recursos Geoespaciales con Tecnología OpenLayers, una aplicación que combina diversas herramientas (OpenLayers, GeoServer, PostgreSQL, jQuery…) – todas ellas basadas en Software Libre – para cumplir funcionalidades como la creación de primitivas vectoriales sobre un mapa, gestión y visualización de la información asociada, edición de estilos, modificación de coordenadas, etc. siendo todas éstas funcionalidades características de un Sistema de Información Geográfica (SIG) y ofreciendo una interfaz de uso cómoda y eficaz, que abstraiga al usuario de detalles internos y complejos. El material desarrollado dispone del potencial necesario para convertirse en una solución a las necesidades de gestión de información geoespacial de la ULPGC, especialmente en el campus de Tafira, sobre el que se ha ejemplificado su uso. Además, a diferencia de las herramientas ofertadas por empresas como Google o Microsoft, esta aplicación está por completo bajo una licencia GNU GPL v3, lo que permite que se pueda indagar dentro de su código, mejorarlo y añadir funcionalidades a cualquier persona interesada.

A Low Consumption Real Time Environmental Monitoring System for Smart Cities based on ZigBee Wireless Sensor Network

Nowadays, there is an increasing interest in wireless sensor networks (WSN) for environmental monitoring systems because it can be used to improve the quality of life and living conditions are becoming a major concern to people. This paper describes the design and development of a real time monitoring system based on ZigBee WSN characterized by a lower energy consumption, low cost, reduced dimensions and fast adaptation to the network tree topology. The developed system encompasses an optimized sensing process about environmental parameters, low rate transmission from sensor nodes to the gateway, packet parsing and data storing in a remote database and real time visualization through a web server.

Programmazione asincrona in JavaScript

L’obiettivo della tesi è esplorare gli aspetti fondamentali che riguardano la programmazione asincrona, in particolare in JavaScript, analizzando le librerie e i metodi piu` diffusi per risolvere problemi tipici di asincronicità. Il motivo dello studio di JavaScript è il grande utilizzo di tale linguaggio per la costruzione delle moderne web-app. Per la realizzazione di questo elaborato si è partiti dallo studio dell’evoluzione del web, dal Web 1.0 al web 2.0 e dall’evoluzione delle web app in questo contesto, successivamente si è raffinata la ricerca allo studio più specifico di JavaScript e, di conseguenza, ai suoi costrutti ed ai suoi stili di programmazione, come la programmazione asincrona e la programmazione ad eventi.

Medicalgenomics.org : an open source database and retrieval system for biomedical analysis

Die Molekularbiologie von Menschen ist ein hochkomplexes und vielfältiges Themengebiet, in dem in vielen Bereichen geforscht wird. Der Fokus liegt hier insbesondere auf den Bereichen der Genomik, Proteomik, Transkriptomik und Metabolomik, und Jahre der Forschung haben große Mengen an wertvollen Daten zusammengetragen. Diese Ansammlung wächst stetig und auch für die Zukunft ist keine Stagnation absehbar. Mittlerweile aber hat diese permanente Informationsflut wertvolles Wissen in unüberschaubaren, digitalen Datenbergen begraben und das Sammeln von forschungsspezifischen und zuverlässigen Informationen zu einer großen Herausforderung werden lassen. Die in dieser Dissertation präsentierte Arbeit hat ein umfassendes Kompendium von humanen Geweben für biomedizinische Analysen generiert. Es trägt den Namen medicalgenomics.org und hat diverse biomedizinische Probleme auf der Suche nach spezifischem Wissen in zahlreichen Datenbanken gelöst. Das Kompendium ist das erste seiner Art und sein gewonnenes Wissen wird Wissenschaftlern helfen, einen besseren systematischen Überblick über spezifische Gene oder funktionaler Profile, mit Sicht auf Regulation sowie pathologische und physiologische Bedingungen, zu bekommen. Darüber hinaus ermöglichen verschiedene Abfragemethoden eine effiziente Analyse von signalgebenden Ereignissen, metabolischen Stoffwechselwegen sowie das Studieren der Gene auf der Expressionsebene. Die gesamte Vielfalt dieser Abfrageoptionen ermöglicht den Wissenschaftlern hoch spezialisierte, genetische Straßenkarten zu erstellen, mit deren Hilfe zukünftige Experimente genauer geplant werden können. Infolgedessen können wertvolle Ressourcen und Zeit eingespart werden, bei steigenden Erfolgsaussichten. Des Weiteren kann das umfassende Wissen des Kompendiums genutzt werden, um biomedizinische Hypothesen zu generieren und zu überprüfen.

Wishlist: progettazione ed implementazione di una piattaforma di mobile social network per dispositivi Android

Questo elaborato tratta della progettazione e dell'implementazione di una piattaforma social, destinata alla commercializzazione, per creare, gestire, condividere un insieme di liste organizzate di oggetti. La piattaforma è di tipo client-server, dove il client consiste in un'applicazione Android e il server in un'applicazione Node.js e un database MySQL che offrono un'API RESTful. Nello specifico è stata trattata l'implementazione delle notifiche push (anche geolocalizzate) e la sincronizzazione dei dati per l'utilizzo offline.

SMARTDIAB: a communication and information technology approach for the intelligent monitoring, management and follow-up of type 1 diabetes patients

SMARTDIAB is a platform designed to support the monitoring, management, and treatment of patients with type 1 diabetes mellitus (T1DM), by combining state-of-the-art approaches in the fields of database (DB) technologies, communications, simulation algorithms, and data mining. SMARTDIAB consists mainly of two units: 1) the patient unit (PU); and 2) the patient management unit (PMU), which communicate with each other for data exchange. The PMU can be accessed by the PU through the internet using devices, such as PCs/laptops with direct internet access or mobile phones via a Wi-Fi/General Packet Radio Service access network. The PU consists of an insulin pump for subcutaneous insulin infusion to the patient and a continuous glucose measurement system. The aforementioned devices running a user-friendly application gather patient's related information and transmit it to the PMU. The PMU consists of a diabetes data management system (DDMS), a decision support system (DSS) that provides risk assessment for long-term diabetes complications, and an insulin infusion advisory system (IIAS), which reside on a Web server. The DDMS can be accessed from both medical personnel and patients, with appropriate security access rights and front-end interfaces. The DDMS, apart from being used for data storage/retrieval, provides also advanced tools for the intelligent processing of the patient's data, supporting the physician in decision making, regarding the patient's treatment. The IIAS is used to close the loop between the insulin pump and the continuous glucose monitoring system, by providing the pump with the appropriate insulin infusion rate in order to keep the patient's glucose levels within predefined limits. The pilot version of the SMARTDIAB has already been implemented, while the platform's evaluation in clinical environment is being in progress.

Managing server energy and reducing operational cost for online service providers

The past decade has seen the energy consumption in servers and Internet Data Centers (IDCs) skyrocket. A recent survey estimated that the worldwide spending on servers and cooling have risen to above $30 billion and is likely to exceed spending on the new server hardware . The rapid rise in energy consumption has posted a serious threat to both energy resources and the environment, which makes green computing not only worthwhile but also necessary. This dissertation intends to tackle the challenges of both reducing the energy consumption of server systems and by reducing the cost for Online Service Providers (OSPs). Two distinct subsystems account for most of IDC’s power: the server system, which accounts for 56% of the total power consumption of an IDC, and the cooling and humidifcation systems, which accounts for about 30% of the total power consumption. The server system dominates the energy consumption of an IDC, and its power draw can vary drastically with data center utilization. In this dissertation, we propose three models to achieve energy effciency in web server clusters: an energy proportional model, an optimal server allocation and frequency adjustment strategy, and a constrained Markov model. The proposed models have combined Dynamic Voltage/Frequency Scaling (DV/FS) and Vary-On, Vary-off (VOVF) mechanisms that work together for more energy savings. Meanwhile, corresponding strategies are proposed to deal with the transition overheads. We further extend server energy management to the IDC’s costs management, helping the OSPs to conserve, manage their own electricity cost, and lower the carbon emissions. We have developed an optimal energy-aware load dispatching strategy that periodically maps more requests to the locations with lower electricity prices. A carbon emission limit is placed, and the volatility of the carbon offset market is also considered. Two energy effcient strategies are applied to the server system and the cooling system respectively. With the rapid development of cloud services, we also carry out research to reduce the server energy in cloud computing environments. In this work, we propose a new live virtual machine (VM) placement scheme that can effectively map VMs to Physical Machines (PMs) with substantial energy savings in a heterogeneous server cluster. A VM/PM mapping probability matrix is constructed, in which each VM request is assigned with a probability running on PMs. The VM/PM mapping probability matrix takes into account resource limitations, VM operation overheads, server reliability as well as energy effciency. The evolution of Internet Data Centers and the increasing demands of web services raise great challenges to improve the energy effciency of IDCs. We also express several potential areas for future research in each chapter.

Monitorización de sistemas en alta disponibilidad

El objetivo del proyecto es implantar un sistema de monitorización, con la peculiaridad de encontrarse en alta disponibilidad, esto es, que el servicio (la monitorización de una infraestructura) se preste forma continua y no se vea interrumpido. Dado que el propósito del sistema es monitorizar activamente una infraestructura, ha sido necesario desplegar una infraestructura, además del sistema de monitorización. La infraestructura en cuestión está compuesta por un servidor de documentación, un servidor de base de datos, un servidor de aplicaciones y un servidor web. El sistema de monitorización se ha desplegado en la misma red de área local de esta infraestructura y monitoriza que los servicios prestados por los componentes de esta infraestructura se encuentren operativos y funcionando adecuadamente. Así pues, se tendría un sistema de monitorización local funcional. No obstante, el proyecto plantea un sistema escalable, que esté preparado para el crecimiento de la infraestructura y continúe siendo eficiente. Para ello, sistema de monitorización se encuentre dividido por dos componentes:  Sonda delegada: monitoriza localmente los activos de la infraestructura a monitorizar, es el escenario anteriormente descrito.  Sonda maestra: recibe los resultados de la monitorización realizada, este sistema puede estar desplegado en otra red distinta a la sonda delegada. Este enfoque no solo es escalable, sino también es fiel a la realidad, pues puede darse el caso de que las sondas pertenezcan a distintas infraestructuras e inclusive, distintas organizaciones, y se comuniquen a través de internet, mediante un mecanismo confiable a ser posible. El proyecto plantea que ambas sondas se encuentren en alta disponibilidad (en adelante HA, referente a high availability), y que cada sonda está compuesta por dos equipos (nodos, en adelante). Como se analizará en posteriores capítulos, existen diversas configuraciones que permiten implantar un sistema en HA, la configuración escogida para el proyecto es Activo – Pasivo(los detalles de esta configuración también se explican en posteriores capítulos). Para finalizar, se estudiara la posibilidad de ofrecer respuestas activas en ciertas situaciones y configuraciones adicionales sobre el sistema de monitorización base. Por otro lado, para la implantación del proyecto se ha usado software de código abierto para la virtualización de la infraestructura (Virtual Box y GNS3), los sistemas operativos base (Linux), el sistema de monitorización(Nagios Core) así como el software que implementa la HA (corosync y pacemaker).---ABSTRACT---The aim of the Project is to implement a monitoring system, with the peculiarity of being deployed in high availability, what it is that the service (monitoring infrastructure) is provided continuously and not interrupted. As the purpose of the system is monitoring infrastructure actively, an infrastructure has been deployed, and also the monitoring system. The infrastructure monitored is composed of a documentation server, a server database, an application server and a Web server. The monitoring system has been also deployed on the same LAN of this infrastructure and monitors the services provided by the components of this infrastructure are operational and working as expected. This is a local monitoring system functional. However, the project also proposes a scalable system that is ready for growth of infrastructure and efficient. This is the reason of divide the system in two components:  Slave Component: monitors locally the infrastructure assets to be monitored, this is the scenario described above.  Master Component: get the results from the monitoring, provided by the Slave Component. This system can be deployed in a different network than the slave component. This approach is not only scalable but also a real scenario, as may be the case that the Components belongs to different infrastructures and even, different organizations, also this components can communicate over the Internet, through a reliable mechanism if possible. The project proposes that both Components are deployed in high availability (HA onwards concerning high availability), each Component is composed of two servers (nodes, hereafter). As will be discussed in later chapters, there are several settings available to deploy a system in HA, the configuration chosen for the project is Active - Passive (details of this configuration are also explained in later chapters). Finally the possibility of offering active responses in certain situations and additional settings on the monitoring system will be discussed. On the other hand, for the implementation of the project, open source software has been used, for virtualization infrastructure (Virtual Box and GNS3), code-based operating systems (Linux), the monitoring system (Nagios core), as well as the software that implements the HA (corosync and pacemaker).

Generación automática de ficheros de configuración para encaminadores

Este Proyecto Fin de Grado (PFG) tiene como objetivo diseñar e implementar un sistema que genere un fichero de texto que contenga la configuración básica de un encaminador. De esta manera se desea mejorar la eficiencia del personal del departamento donde se va a implantar dicho sistema, liberando a los miembros del mismo de un trabajo repetitivo que se hace varias veces al día. Hasta ahora, esta configuración la realiza cada instalador. Para ello, una vez que se ha cargado y probado la configuración en distintos equipos de manera satisfactoria, se generan un conjunto de plantillas que sirven de modelo para las siguientes configuraciones. Aunque el instalador toma estas plantillas como punto de partida, tiene que modificar manualmente todas las variables que dependen de cada configuración particular. Por tanto, aunque no ha de ejecutar todos los comandos paso a paso, sí debe hacer una revisión total de cada plantilla para generar la configuración adecuada y después cargarla en el encaminador. Para cada configuración se consultan un total de entre tres y siete plantillas. Si a esto se añade que en el departamento se configuran encaminadores de la marca Cisco y Teldat, que de cada marca se utilizan distintos modelos y que la empresa ofrece cuatro tipos de servicio, cada uno con sus particularidades, la tarea de configurar un equipo es costosa. El sistema estará constituido por un servidor web que alojará una base de datos y un programa que permite realizar operaciones de consulta sobre la misma, un sitio web sencillo que hará las funciones de interfaz de usuario y una aplicación que permite generar el fichero de texto que contiene la configuración del encaminador en base a una serie de condicionantes. La base de datos desarrollada es una representación de la utilizada en el entorno real que tiene como objetivo realizar simulaciones del funcionamiento que tendrá el sistema. Por su parte, la funcionalidad del sitio web debe ser la de ofrecer al usuario una interfaz sencilla de utilizar y de interpretar, a través de la cual se puedan realizar consultas a la base de datos así como presentar los resultados de dichas consultas de forma ordenada. La aplicación se encargará de validar los datos a partir de los que se va a generar la configuración, determinar qué plantillas se deben consultar en función a aspectos como el servicio a configurar o la marca del encaminador y finalmente generar el fichero de texto resultado. De este modo, el instalador simplemente tendrá que volcar la información de dicho fichero sobre el encaminador. El sistema se ha diseñado de manera que sea lo más flexible a cambios, puesto que la idea de los miembros del departamento es ampliar la funcionalidad de esta herramienta. ABSTRACT. This Final Degree Project is focused on the design and implementation of a system which is able to generate a text file that contains the basic configuration of a router. With this system we want to improve the efficiency of the department members where this system is going to be introduced, releasing them from repetitive work which is done several times per day. Up to now, each installer has to configure the router manually. After checking the configuration of several devices successfully, they create a set of templates which work as models. Although the installers use those templates, they have to modify the variables that depend on the specific features of each kind of configuration. Thus, even though they don´t have to execute the commands step by step, they have to do a review of each used template in order to generate the right configuration. For each configuration, three to seven templates have to be checked. In addition, if the configured routers are both Cisco and Teldat, there are several models per brand and the company offers four types of services to be installed, so the configuration becomes a hard task to do. The system is comprised of a web server in which both the database and the program responsible for doing queries are hosted, a simple web site that will be the graphic user interface, and an application focused on generating the text file which contains the router configuration based on a set of conditions. The developed database is the representation of the real one and its aim is to simulate the way the system will work. The function of the web site is to offer an easy interface whereby you can submit a query or you can see the obtained results as a data table. Furthermore, the application has to validate the data in which the text file with the router configuration is based on. Then, it has to decide which templates it is going to use according to different aspects, such as the brand of the router or the type of service we want to configure. Finally, the application generates a text file with the necessary commands. As a result of this, the user of the system only has to copy the contents of this file to the router. The system has been designed to be flexible to changes because the members of the department want to increase the utility of this tool in the future.