Estudo da presença de Mycobacterium avium subespécie paratuberculosis numa exploração leiteira no Litoral Centro de Portugal Continental

A Paratuberculose, conhecida também como Doença de Johne, é uma afeção infecciosa que provoca uma enterite granulomatosa crónica causada pelo agente Mycobacterium avium subespécie paratuberculosis (Map). É uma doença de carácter contagioso, de distribuição mundial, atingindo os mamíferos, particularmente os pequenos e grandes ruminantes, equinos, suínos, búfalos, coelhos, etc. Tem um grande impacto económico, nomeadamente na redução da produção leiteira, na redução dos teores de proteína no leite, na susceptibilidade a outras doenças, no refugo de animais e no aumento dos custos na sanidade. Pensa-se que também terá impacto a nível de Saúde Pública uma vez que o Map pode estar associado á doença de Crohn em humanos em que o leite cru, leite em pó ou leite pasteurizado podem ser os veículos de transmissão, porém não existem estudos suficientes para sustentar este acontecimento. A técnica de diagnóstico “Gold Standard” é a cultura microbiológica de fezes, no entanto é um procedimento muito demorado podendo levar até 4 meses para se observarem as colónias bacterianas, uma vez que o seu crescimento é muito lento. Deste modo, existem outros testes, tais como o PCR e ELISA, com elevada especificidade para o agente que fornecem resultados mais rápidos e que permitem minimizar os falsos-positivos, apesar da sua reduzida sensibilidade (por volta dos 50%). Este estudo é baseado na observação das instalações da exploração e consequente comparação com parâmetros analisados e documentados em literatura. Para além disso, são utilizadas informações fornecidas pelo Software da exploração com o intuito de estudar a incidência da Paratuberculose, ao longo dos anos, de modo a comprovar se as medidas de maneio e de higiene adotadas pela exploração afetada contribuem ou não de alguma maneira para o controlo/erradicaçãoda doença de Johne.

Percepção Ambiental em Museus Paisagens de Arte Contemporânea: a legibilidade dos museus Inhotim/Brasil e em Serralves/Portugal avaliada pelo público/visitante

This thesis nalyzes the wayfinding in Landscape Museum of Contemporary Art (MPAC), based on the Institute of Contemporary Art CACI, Minas Gerais, Brazil and the Museum of Contemporary Art of the Serralves Foundation, Porto, Portugal. The study focuses on the interrelationship of the public/visitors with the landscape, architecture and contemporary art museums in these, in order to understand visual perception and apprehension of such an environment for their users. For both were confronted documentation (visual and written) and people talk. The main hypothesis put forward is that the audience/visitor MPAC appreciates the interrelationship between the natural environment (park/garden) and built environment (the works of contemporary art and the galleries), giving equal value to both. To complement this, a second hypothesis is that during the visit to MPACS, visitors define their paths spontaneously, but strongly influenced by existing visual indicators (maps, signage and striking landscape elements), which facilitate the readability of space, which also contribute to the offered services and the experiences of similar institutions. The analytical basis of the research used the concepts of legibility (LYNCH, 2009), wayfinding (GIBSON, 2009; ARTHUR, PASSINI, 2002; WEISMAN, 1982), Experiential Cotinnum (TUAN, 1985), Space Bound (CRUZ PINTO, 2007) and habitus (BOURDIEU, 1992). Methodologically was used qualitative research (DEMO 2000) by means of a case study (YIN, 2005; STAKE, 1999) and participant observation (WHYTE, 2005). In the two institutions interviews with researchers and curators, behavior observation and questionnaires from employees, trainees, monitors and the public/visitor of the two museums were performed. Although partially referende the initial hypothesis, the research showed that the public/visitor value appears more natural environments, they experience a greater intensity and in addition to the factors listed in the second case, your perception and definition of paths suffer significant influence of emotional relations established with space. Generally the audience/visitor adapts easily to different demands of contemporary art exhibition in the two museums and the built environment (park/garden and museum) interferes with your reading path during the visit, perceived by the public/visitor condition as a factor that favors the enjoyment of works on different mounts (wayfinding), though often become a factor that hinders the legibility of the building and its built environment

A idéia de império e a fundação da monarquia constitucional no Brasil (Portugal-Brasil, 1772-1824)

Cet article met les conceptions et projets politiques ayant trait au processus conduisant à la constituion impériale brésilienne de 1824 dans un contexte historique dont le pont de départ est la notion d'empire civil, telle qu'elle se développa lors de la réorganisation politico-administrative du royaume et de l'empire du Portugal au XVIIIe siècle. Le texte montre qu'avec le couronnement de Pierre I on fit un usage moderne d'une institution ancienne, le sacre royal, ce qui servit à étayer une sujection politique fondée sur la raison universelle humaine. Cette étude permet de comprendre pourquoi le Brésil indépendant fut pour commencer un empire, pas un royaume, ainsi que le sens profond du pouvoir modérateur attribué à l'empereur par la constitution de 1824.

Pedro Nunes e a distinção de dois tipos de trajetórias na navegação: a linha de rumo e o círculo máximo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A expressão da cultura nobiliárquica nos livros de viagens medievais

Pós-graduação em História - FCHS

Aedes aegypti on Madeira Island (Portugal): genetic variation of a recently introduced dengue vector

The increasing population of Aedes aegypti mosquitoes on Madeira Island (Portugal) resulted in the first autochthonous dengue outbreak, which occurred in October 2012. Our study establishes the first genetic evaluation based on the mitochondrial DNA (mtDNA) genes [cytochrome oxidase subunit I (COI) and NADH dehydrogenase subunit 4 (ND4)] and knockdown resistance ( kdr ) mutations exploring the colonisation history and the genetic diversity of this insular vector population. We included mosquito populations from Brazil and Venezuela in the analysis as putative geographic sources. The Ae. aegyptipopulation from Madeira showed extremely low mtDNA genetic variability, with a single haplotype for COI and ND4. We also detected the presence of two important kdr mutations and the quasi-fixation of one of these mutations (F1534C). These results are consistent with a unique recent founder event that occurred on the island of Ae. aegyptimosquitoes that carry kdr mutations associated with insecticide resistance. Finally, we also report the presence of the F1534C kdr mutation in the Brazil and Venezuela populations. To our knowledge, this is the first time this mutation has been found in South American Ae. aegypti mosquitoes. Given the present risk of Ae. aegypti re-invading continental Europe from Madeira and the recent dengue outbreaks on the island, this information is important to plan surveillance and control measures.

De um falsário a outro, de patranhas viageiras a legados críveis (século XV)

In the 15th and early 16th centuries, when traveling eastward and westward no longer proved extraordinary, travel writings, such as those of Marco Polo or Jean de Mandeville, were printed and reprinted and have been in the world of exchanges and acquisitions both in Portugal and in other parts of Europe. However, although they have played a key role in defining foreign worlds for Europe, reflecting the aspirations of their time and providing news about the universe to be discovered, these reports do not always necessarily tell of trips that were actually taken. Several of them, on the contrary, do no more than draw together, for contemporary readers, passages of interest taken from other writings; passages which, based on their regularity and frequency, would allow for a narrative staged as travel to be taken as truth for contemporaries and immediate successors. In the Iberian Peninsula of the late 15th century, an account written by an author about whom nothing is known, Gomez de Santisteban, who defines himself as a companion of Prince Pedro on a supposed trip to the Holy Land, was among those reports integrated into the description and the perception of the land being discovered. The driving question of this paper is, therefore, how Santisteban, though he wrote memories of trips that he did not take, achieved credibility like those travelers whose trips have been recognized as authentic.

Role of food availability in the bathymetric distribution of the starfish "Marthasterias glacialis" (Lamk.) on reefs of northern Portugal

[EN] We examined whether the abundance and size of the starfish Marthasterias glacialis (Lamk.) exhibit a depth-dependent partitioning on subtidal reefs. We tested the hypothesis that differences in food availability can result in habitat partitioning along a depth gradient. The abundance and size of M. glacialis was registered at 4 depth strata: 0-4 m, 4-8 m, 8-12 m, and >12 m; we also recorded the number of food items that they were preying on. The abundance and size of M. glacialis decreased with depth. Mussels (Mytilus galloprivincialis) were the most preyed food item across all depth strata, followed by gastropods, sea urchins and barnacles; M. glacialis also consumed a significantly larger amount of mussels in feeding experiments compared with sea urchins and gastropods. The abundance of M. galloprivincialis beds decreased with depth. The clear link between the decrease in abundance and size of M. glacialis with depth and the decay of the most consumed prey (mussels) suggest that food availability may play an important role in the vertical distribution of this starfish, though wave-associated turbulence in the first few metres of the subtidal could also limit the abundance of M. glacialis.

Compendio de la vida del glorioso martir San Pedro Pasqual de Valencia, del celeste, real y militar Orden de N.Señora de la Merced ...

Sign.: [calderon]4, *2, A-G4

Auiendose dado garrote a Pedro Antonio de Riuera, de orden del... Duque de Veragua, Virrey... de este Reyno de Valencia, de que han resultado algunas resoluciones del... Arçobispo... por pretender era eclesiastico.

Hay un ejemplar encuadernado con: Manifestacion iuridica sobre el derecho de inmunidad y sagrado de las iglesias y monasterios, paraque [sic] no se hagá extracciones viole>tas de los refugiados à ellas por la Iusticia secular.. (XVII/42).

Vida admirable del sieruo de Dios, Fray Pedro Esteue, predicador apostolico ... Christoval Mercader Religioso ... , Predicador ... y Coronista de la Santa Provincia de la Observancia de Valencia ; sacala a luz acosta [sic] de Don Manuel Mercader ... hermano del Autor

Sign.: [calderón]4, 2[calderón]4, A-Z4, Aa-Zz4, Aaa4

Declaracion de su alteza el serenissimo Infante Cardenal tocante a la guerra contra la Corona de Francia

El lugar de producción de Pedro Madrigal y su familia es Madrid

Las vistas de los puertos de Francia, España y Portugal

Las vistas de los puertos de Francia, España y Portugal

Cronica de don Pedro Niño, conde de Buelna [Texto impreso]

Sign.: [asterisco]4, A-Z4, Aa-Gg4

An Economic History of Portugal, 1143-2010

This book is about the evolution of the Portuguese economy during the course of eight centuries, from the foundation of the kingdom, in 1143, when political boundaries began to take shape in the midst of the Christian Reconquista of the Iberian Peninsula, to the integration of the nation in the European Communities and the Economic and Monetary Union. While the economy we are interested in responded to external influences across the land and sea borders, its activity also exerted influence on events occurring elsewhere.