The past, present and future of renin-angiotensin aldosterone system inhibition.

The renin-angiotensin aldosterone system (RAAS) is central to the pathogenesis of cardiovascular disease. RAAS inhibition can reduce blood pressure, prevent target organ damage in hypertension and diabetes, and improve outcomes in patients with heart failure and/or myocardial infarction. This review presents the history of RAAS inhibition including a summary of key heart failure, myocardial infarction, hypertension and atrial fibrillation trials. Recent developments in RAAS inhibition are discussed including implementation and optimization of current drug therapies. Finally, ongoing clinical trials, opportunities for future trials and issues related to the barriers and approvability of novel RAAS inhibitors are highlighted.

Díaz-Andreu, Margarita: A world history of nineteenth century archaeology. Nationalism, Colonialism, and the Past.

M. Díaz-Andreu plantea un análisis de las implicaciones académicas, sociales y políticas de la arqueología (entendiendo como tal la investigación estricta, pero también el coleccionismo de obras de arte) entre finales del siglo XVIII y el inicio de la Primera Guerra Mundial, período durante el cual la formación y expansión de los imperios coloniales constituyó uno de los elementos clave en el discurso ideológico de los estados europeos. Su trabajo continúa la línea marcada por estudios suyos anteriores, esencialmente Nationalism and Archaeology in Europe (Díaz-Andreu & T. Champion [eds.], 1996) y Excavating Women. A History in European Archaeology (Díaz-Andreu & M. L. S. Sorensen, 1998), en los que combinaba el análisis historiográfico de diferentes aspectos y personajes clave de la arqueología europea desde la perspectiva de la organización de las redes sociales entre investigadores, con la reflexión sobre las implicaciones de la arqueología como ciencia en la definición y defensa de diferentes credos políticos, y el papel de la mujer en la investigación.

Pieces of Iowa’s Past, January 16, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. January 16, 2008

Pieces of Iowa’s Past, January 16, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. January 30, 2008

Pieces of Iowa’s Past, January 23, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. January 23, 2008 THIS WEEK: Capitol Quotations

Pieces of Iowa’s Past, February 6, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. February 6, 2008 THIS WEEK: “War of the Rebellion”

Pieces of Iowa’s Past, February 13, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. February 13, 2008 THIS WEEK: “The Great Tornado of 1860”

Pieces of Iowa’s Past, February 20, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. February 20, 2008 THIS WEEK: “The Old Brick Capitol”

Pieces of Iowa’s Past, February 27, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. February 27, 2008 THIS WEEK: Tunnel of Progress

Pieces of Iowa’s Past, March 5, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. March 5, 2008 THIS WEEK: Panama Exposition

Pieces of Iowa’s Past, March 12, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. March 12, 2008 THIS WEEK: University of Iowa Historic “Income Fund

Pieces of Iowa’s Past, March 19, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. March 19, 2008 THIS WEEK: Historical Account of Iowa State University Staff and Enrollment and University of Northern Iowa Financial Reports

Pieces of Iowa’s Past, March 26, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. March 26, 2008 THIS WEEK: Windstorm Damage to the Capitol

Pieces of Iowa’s Past, April 2, 2008

Pieces of Iowa’s Past, published by the Iowa State Capitol Tour Guides weekly during the legislative session, features historical facts about Iowa, the Capitol, and the early workings of state government. All historical publications are reproduced here with the actual spelling, punctuation, and grammar retained. April 2, 2008 THIS WEEK: The Cardiff Giant