The relationship between training status, blood pressure and uric acid in adults and elderly

Background: Hypertension can be generated by a great number of mechanisms including elevated uric acid (UA) that contribute to the anion superoxide production. However, physical exercise is recommended to prevent and/or control high blood pressure (BP). The purpose of this study was to investigate the relationship between BP and UA and whether this relationship may be mediated by the functional fitness index.Methods: All participants (n = 123) performed the following tests: indirect maximal oxygen uptake (VO2max), AAHPERD Functional Fitness Battery Test to determine the general fitness functional index (GFFI), systolic and diastolic blood pressure (SBP and DBP), body mass index (BMI) and blood sample collection to evaluate the total-cholesterol (CHOL), LDL-cholesterol (LDL-c), HDL-cholesterol (HDL-c), triglycerides (TG), uric acid (UA), nitrite (NO2) and thiobarbituric acid reactive substances (T-BARS). After the physical, hemodynamic and metabolic evaluations, all participants were allocated into three groups according to their GFFI: G1 (regular), G2 (good) and G3 (very good).Results: Baseline blood pressure was higher in G1 when compared to G3 (+12% and +11%, for SBP and DBP, respectively, p<0.05) and the subjects who had higher values of BP also presented higher values of UA. Although UA was not different among GFFI groups, it presented a significant correlation with GFFI and VO2max. Also, nitrite concentration was elevated in G3 compared to G1 (140±29 μM vs 111± 29 μM, for G3 and G1, respectively, p<0.0001). As far as the lipid profile, participants in G3 presented better values of CHOL and TG when compared to those in G1.Conclusions: Taking together the findings that subjects with higher BP had elevated values of UA and lower values of nitrite, it can be suggested that the relationship between blood pressure and the oxidative stress produced by acid uric may be mediated by training status. © 2013 Trapé et al.; licensee BioMed Central Ltd.

Relação entre parâmetros fisiológicos aeróbios e anaeróbios com o desempenho de ciclistas

Pós-graduação em Fisioterapia - FCT

Comparação de parâmetros cardiorrespiratórios em testes indiretos e diretos de avaliação funcional em indivíduos saudáveis e diabéticos

Pós-graduação em Ciências da Motricidade - IBRC

Efeitos do treinamento de caminhada com restrição do fluxo sanguíneo sobre economia de corrida em indivíduos ativos

Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

Efeitos do treinamento de caminhada em declive sobre índices de aptidão aeróbia

Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

Efeito do nível do treinamento aeróbio na determinação do limite superior do domínio pesado no ciclismo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito da duração do estímulo e do tipo de recuperação nas respostas metabólicas e cardiorrespiratórias durante um exercício intermitente realizado no domínio severo em indivíduos ativos

Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

Associações entre, índices fisiológicos e fadiga neuromuscular com padrões de deslocamento e desempenho do chute de finalização no futsal

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Metabolismo oxidativo e cardíaco de equinos submetidos a exercício de baixa intensidade antes e após suplementação com antioxidante

The present study aimed to evaluate cardiac and lipoperoxidation markers in horses subjected to low intensity and long duration (TLD) exercise test, before and after vitamin E supplementation. For this purpose, 10 horses were used, subjecting them to the first TLD with a workload based on individual maximal oxygen uptake (VO2max). Then, horses received vitamin E (dl-alpha-tocopherol) during 59 days at a daily oral dose of 1,000IU, and thereafter they performed a second TLD with the same protocol as the first. Blood samples were collected to determine plasma malondialdehyde (MDA) as an index of lipoperoxidation, serum cardiac troponin I (cTnI) and creatine kinase MB isoenzyme (CK-MB) as cardiac markers. As a result of the exercise, there was no significant increase in MDA or cTnI, but serum CK-MB increased suggesting myocardial stress. The supplementation was able to minimize reactive oxygen species production, as evidenced by lower concentrations of MDA at all times evaluated, but it didn't cause protective effect on the myocardium. It was concluded that the low intensity and long duration exercise promoted light myocardial stress in horses and vitamin E supplementation reduced lipoperoxidation.

Aptidão aeróbia e amplitude dos domínios de intensidade de exercício no ciclismo

INTRODUÇÃO: A determinação dos domínios de intensidade de exercício tem importantes implicações na prescrição do treino aeróbio e na elaboração de delineamentos experimentais. OBJETIVO: Analisar os efeitos do nível de aptidão aeróbia sobre a amplitude dos domínios de intensidade de exercício durante o ciclismo. MÉTODOS: Doze ciclistas (CIC), 11 corredores (COR) e oito indivíduos não treinados (NT) foram submetidos aos seguintes protocolos em diferentes dias: 1) teste progressivo para determinação do limiar de lactato (LL), consumo máximo de oxigênio (VO2máx) e sua respectiva intensidade (IVO2máx); 2) três testes de carga constante até a exaustão a 95, 100 e 110% IVO2máx para a determinação da potência crítica (PC); 3) testes até a exaustão para determinar a intensidade superior do domínio severo (Isup). As amplitudes dos domínios (moderado < LL; LL > pesado < PC; PC > severo < Isup) foram expressas como percentual da Isup (VO2). RESULTADOS: A amplitude do domínio moderado foi similar entre CIC (52 ± 8%) e COR (47 ± 4%) e significantemente maior no CIC em relação ao NT (41 ± 7%). O domínio pesado foi significantemente menor no CIC (17 ± 6%) em relação ao COR (27 ± 6%) e NT (27 ± 9%). Em relação ao domínio severo não foram encontradas diferenças significantes entre os CIC (31 ± 7%), COR (26 ± 5%) e NT (31 ± 7%). CONCLUSÃO: O domínio pesado de exercício é mais sensível a mudanças determinadas pelo nível de aptidão aeróbia, existindo a necessidade de que se atenda ao princípio da especificidade do movimento, quando se pretende obter um elevado grau de adaptação fisiológica.

Efeitos do dano muscular sobre indicadores neuromusculares e de aptidão aeróbia

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Correlações entre parâmetros aeróbios e desempenho em esforços intermitentes de alta intensidade

The purpose of the study was to examine the relationships between intermittent high-intensity efforts (RAST) parameters and variables related to aerobic metabolism (anaerobic threshold; LAN, maximal oxygen uptake; VO2MAX and velocity correspondent to VO2MAX; iVO(2MAX)). Eight under-17 (U17) soccer players (16 +/- 1 years) participated in the study. The participants were submitted to a graded exercise test and six maximal sprints of 35m with 10 seconds of passive recovery between each effort (RAST). The RAST parameters were not significant correlated with VO2MAX and LAN. However absolute and relative mean power were significantly correlated with iVO(2MAX) (r=0.79 e r=0.85, respectively). Furthermore, the fatigue index and the relative peak power were significantly correlated with the iVO(2MAX) (r=-0,57 e r=0,73, respectively). In conclusion, the only aerobic variable correlated with performance in consecutive efforts with brief recovery periods, such as RAST, is iVO(2MAX).

Reprodutibilidade das respostas metabólicas e cardiorrespiratórias fisiológicas em um protocolo de exercício intermitente realizado com recuperação passiva e ativa

The main objective of this study was to analyze the reliability of blood lactate concentration ([La]), oxygen uptake (VO2) and heart rate (FC) in an intermittent protoco, performed at 95%VO2max with passive or active recovery in untrained subjects. Participated of this study, active healthy males with 20 to 25 years, which were doing aerobic exercises witha weekly frequency of 3 sessions at least. The individulas performed, in different days, the following protocols in a cyclergometer: 1) An incremental test until exhaustion to determine maximal oxygen uptake (VO2max) and the intensity at VO2max; b) Two transitions at 95%VO2max for the determination of the VO2 kinetics parameters and; c) Two intermittent tests until exhaustion, with repetitions at 95% IVO2max and with durantion defined as being half of the duration of the slow component. The duration of the recovery was half of the duration of the effort (effort:pause of 2:1). This test was performed with passive (GP) and active recovery (GA). The VO2 and FC were measured continulously in both tests. Blood collections were performed for the determination of the [La]. There was significant correlação in both groups for VO2 (ATIVA - 0.94, PASSIVA - 0.75), [La] (ATIVA - 0.83, PASSIVA - 0.90) and FC (0.93) only for the passive group. Thus, it can be concluded that the cardiorrespiratory and metabolic responses present good realiability in an intermittent exercise with active or passive recovery

Efeito do exercício prévio na determinação da potência crítica

The objective of this study was to analyze the influence of previous exercise on the determination of critical power (CP). Seven apparently healthy nontrained males, of 18 to 25 years, participated of this study. The subjects were submitted, in different days to the following protocols in a cyclergometer: 1) one progressive test until voluntary exhaustion for the determination of lactate threshold (LL), maximal oxygen uptake (VO2max) and its corresponding intensity (IVO2max); 2) six constant workload tests at 95,100 and 110% IVO2max until exhaustion with and without a previous exercise at 70% , in random order. The exhaustion times (tlim) at 95, 100 and 110% IVO2max were adjusted forme thress models of two parameters to estimate CP and anaerobic work capacity (AWC) [P=CTAn/tlim)+CP; tlim = CTAn/(P-PC); P=PC.tlim+ CTAn]. The model with the lowest standard error was considered for the estimation of CP. The tlim at 95% IVO2max was similar without (501 ± 140 s) and with previous exercise (473 ± 99 s). However, the tlim at 100% (381 ± 103 s and 334 ± 101 s) and 110% IVO2max (267 ± 163 s and 227 ± 68 s) was significantly longer with previous exercise. There was no significant difference in CP and AWCat conditions without (200 ± 27 W and 23 ± 11 kJ, respectively) and with previous exercise (212 ± 30 W and 18 ± 8 kJ, respectively). It can be concluded that the parameters of the relationship between power and time were not modified by the previous severe exercise

Efeito da suplementação com vitamina E sobre os metabolismos oxidativo e cardíaco em equinos submetidos a exercício de alta intensidade

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)