Injustiça e poder segundo Noam Chomsky

Injustice and power according to Noam Chomsky. In the beginning of the Politics, Aristotle establishes the two lesser forms of sociability: the relationships between man and woman and between master and the slave. In this context, he observes that “Hellenes are natural masters of barbarians” and the reason is that Greeks know philosophy and barbarians still resort to violence (ARISTOTLE, Politics, 1252a.). Shortly after defines “just war” as a war that has a fair cause, that is, which is well justified by philosophy or a fair speech (ARISTOTLE, Politics, 1255a.). This scene briefly expresses the manner in which the USA understands their role in the contemporary world. Chomsky points out the political use of massive military force of his country and denounces how it articulates internally and externally. He affirms that politics is excessively submitted to “ideology”, to doxa, as opposed to natural sciences. His militancy, thus, only advocates freedom and unrestricted right to information. In Camelot, the Kennedy years (1993), for example, the MIT’s professor collects information from congressmen’s speeches and government officials and from secret documents made public and he explicits the methods and actions of the US government. Thereby he can conclude that the US has, for historical reasons, an internal posture that is advocate or contrary to what they imposes to other countries. Power and justice on the one hand, force and injustice on the other –according to their own political discourse.

From defined polymer architectures to structure-property relationships in vivo

Makromolekulare Wirkstoffträgersysteme sind von starkem Interesse bezüglich der klinischen Anwendung chemotherapeutischer Agenzien. Um ihr klinisches Potential zu untersuchen ist es von besonderer Bedeutung das pharmakokinetische Profil in vivo zu bestimmen. Jede Veränderung der Polymerstruktur beeinflusst die Körperverteilung des entsprechenden Makromoleküls. Aufgrund dessen benötigt man detailliertes Wissen über Struktur-Eigenschaftsbeziehungen im lebenden Organismus, um das Nanocarrier System für zukünftige Anwendungen einzustellen. In dieser Beziehung stellt das präklinische Screening mittels radioaktiver Markierung und Positronen-Emissions-Tomographie eine nützliche Methode für schnelle sowie quantitative Beobachtung von Wirkstoffträgerkandidaten dar. Insbesondere poly(HPMA) und PEG sind im Arbeitsgebiet Polymer-basierter Therapeutika stark verbreitet und von ihnen abgeleitete Strukturen könnten neue Generationen in diesem Forschungsbereich bieten.rnDie vorliegende Arbeit beschreibt die erfolgreiche Synthese verschiedener HPMA und PEG basierter Polymer-Architekturen – Homopolymere, Statistische und Block copolymere – die mittels RAFT und Reaktivesterchemie durchgeführt wurde. Des Weiteren wurden die genannten Polymere mit Fluor-18 und Iod-131 radioaktiv markiert und mit Hilfe von microPET und ex vivo Biodistributionsstudien in tumortragenden Ratten biologisch evaluiert. Die Variation in Polymer-Architektur und darauffolgende Analyse in vivo resultierte in wichtige Schlussfolgerungen. Das hydrophile / lipophile Gleichgewicht hatte einen bedeutenden Einfluss auf das pharmakokinetische Profil, mit besten in vivo Eigenschaften (geringe Aufnahme in Leber und Milz sowie verlängerte Blutzirkulationszeit) für statistische HPMA-LMA copolymere mit steigendem hydrophoben Anteil. Außerdem zeigten Langzeitstudien mit Iod-131 eine verstärkte Retention von hochmolekularen, HPMA basierten statistischen Copolymeren im Tumorgewebe. Diese Beobachtung bestätigte den bekannten EPR-Effekt. Hinzukommend stellen Überstrukturbildung und damit Polymergröße Schlüsselfaktoren für effizientes Tumor-Targeting dar, da Polymerstrukturen über 200 nm in Durchmesser schnell vom MPS erkannt und vom Blutkreislauf eliminiert werden. Aufgrund dessen wurden die hier synthetisierten HPMA Block copolymere mit PEG Seitengruppen chemisch modifiziert, um eine Verminderung in Größe sowie eine Reduktion in Blutausscheidung zu induzieren. Dieser Ansatz führte zu einer erhöhten Tumoranreicherung im Walker 256 Karzinom Modell. Generell wird die Körperverteilung von HPMA und PEG basierten Polymeren stark durch die Polymer-Architektur sowie das Molekulargewicht beeinflusst. Außerdem hängt ihre Effizienz hinsichtlich Tumorbehandlung deutlich von den individuellen Charakteristika des einzelnen Tumors ab. Aufgrund dieser Beobachtungen betont die hier vorgestellte Dissertation die Notwendigkeit einer detaillierten Polymer-Charakterisierung, kombiniert mit präklinischem Screening, um polymere Wirkstoffträgersysteme für individualisierte Patienten-Therapie in der Zukunft maßzuschneidern.rn

THE APPLICATION OF PATH ANALYSIS TO ASSESSMENT OF IRON NUTRITIONAL STATUS IN MAN

Path analysis has been applied to components of the iron metabolic system with the intent of suggesting an integrated procedure for better evaluating iron nutritional status at the community level. The primary variables of interest in this study were (1) iron stores, (2) total iron-binding capacity, (3) serum ferritin, (4) serum iron, (5) transferrin saturation, and (6) hemoglobin concentration. Correlation coefficients for relationships among these variables were obtained from published literature and postulated in a series of models using measures of those variables that are feasible to include in a community nutritional survey. Models were built upon known information about the metabolism of iron and were limited by what had been reported in the literature in terms of correlation coefficients or quantitative relationships. Data were pooled from various studies and correlations of the same bivariate relationships were averaged after z- transformations. Correlation matrices were then constructed by transforming the average values back into correlation coefficients. The results of path analysis in this study indicate that hemoglobin is not a good indicator of early iron deficiency. It does not account for variance in iron stores. On the other hand, 91% of the variance in iron stores is explained by serum ferritin and total iron-binding capacity. In addition, the magnitude of the path coefficient (.78) of the serum ferritin-iron stores relationship signifies that serum ferritin is the most important predictor of iron stores in the proposed model. Finally, drawing upon known relations among variables and the amount of variance explained in path models, it is suggested that the following blood measures should be made in assessing community iron deficiency: (1) serum ferritin, (2) total iron-binding capacity, (3) serum iron, (4) transferrin saturation, and (5) hemoglobin concentration. These measures (with acceptable ranges and cut-off points) could make possible the complete evaluation of all three stages of iron deficiency in those persons surveyed at the community level. ^

ARREDA HOMEM QUE AÍ VEM MULHER... Representações de Gênero nas Manifestações da Pombagira

Arreda homem que aí vem mulher... , trata das representações de gênero nas manifestações da Pombagira, entidade espiritual da religiosidade afro-brasileira. O trabalho faz uma leitura diferenciada sobre a figura da Pombagira trazendo-a para o campo social, mostrando sua construção e suas funções, desmistificando sua associação com o mal que supomos esteja relacionado com a sua função de intermediadora das relações amorosas, vinculadas ao poder via sexualidade, além da sua manifestação como contestadora do papel feminino construído. A pesquisa foi realizada por meio da observação dos rituais e entrevistas semi-estruturadas com sacerdotes, sacerdotisas e adeptos da religiosidade afro-brasileira em terreiros de Candomblé e Umbanda na cidade de Porto Velho - Rondônia. Apresentamos no primeiro capítulo algumas observações sobre as suas imagens, funções e representações. No segundo capítulo trazemos as construções da sua figura pelos cientistas sociais, religiosos, entrevistados e entrevistadas. O terceiro capítulo foi dedicado às observações sobre as representações da Pombagira, objetivo central do trabalho.AU)

ARREDA HOMEM QUE AÍ VEM MULHER... Representações de Gênero nas Manifestações da Pombagira

Arreda homem que aí vem mulher... , trata das representações de gênero nas manifestações da Pombagira, entidade espiritual da religiosidade afro-brasileira. O trabalho faz uma leitura diferenciada sobre a figura da Pombagira trazendo-a para o campo social, mostrando sua construção e suas funções, desmistificando sua associação com o mal que supomos esteja relacionado com a sua função de intermediadora das relações amorosas, vinculadas ao poder via sexualidade, além da sua manifestação como contestadora do papel feminino construído. A pesquisa foi realizada por meio da observação dos rituais e entrevistas semi-estruturadas com sacerdotes, sacerdotisas e adeptos da religiosidade afro-brasileira em terreiros de Candomblé e Umbanda na cidade de Porto Velho - Rondônia. Apresentamos no primeiro capítulo algumas observações sobre as suas imagens, funções e representações. No segundo capítulo trazemos as construções da sua figura pelos cientistas sociais, religiosos, entrevistados e entrevistadas. O terceiro capítulo foi dedicado às observações sobre as representações da Pombagira, objetivo central do trabalho.AU)

Six anonymous plays. First series (c. 1510-1537) comprising Four elements--The beauty and good properties of women (usually known as Calisto and Melibæa)--Every man--Hickscorner--The world and the child--Thersites--Note-book and word-list, ed.

With facsimile reproductions of original title-pages.

Swetnam the woman-hater. 1620.

Interleaved.

The Chinese drama /

"The three plays and two poems ... are reprinted, with slight alterations from the China review."

Miller's modern acting drama, consisting of the most popular pieces produced at the London theatres, subject to the provisions of the Dramatic copyright act ...

Half-title: Modern acting drama.

Tales of the drama. Founded on the tragedies of Shakspeare, Massinger, Shirley, Rowe, Murphy, Lillo, and Moore, and on the comedies of Steele, Farquhar, Cumberland, Bickerstaff, Goldsmith, and Mrs. Cowley.

Duke of Milan.--The inconstant.--The good-natured man.--Introduction to Shakespeare's plays.--King John.--The Quaker.--Edward the Black prince.--The belle's stratagem.--Winter's tale.--George Barnwell.--The conscious lovers.--King Richard II.--The Grecian daughter.--The brothers.--Lady Jane Grey.--The Merchant of Venice.--Coriolanus.--The way to keep him.--The gamester.--The hypocrite.--Julius Cæsar.--Conclusion.

Lady Cheveley; or, The woman of honour.

A satire in verse, written in answer to Lady Bulwer-Lytton's attack on her husband in "Cheveley, the man of honour."

Evenings of a working man : being the occupation of his scanty leisure /

Stories, verses, and essays.

Lectures on the sphere and duties of woman : and other subjects /

Introduction -- Sphere and duties of woman -- Education of woman -- Moral uses of poetry -- The moral nature of man -- Progress and prospects of society.

La comédie humaine of Honoré de Balzac;

"Ed. grand format. Limited to five hundred numbered sets of which this is no. 133."