[Sobre la importancia de los estudios universitarios] : oración inaugural pronunciada en la solemne apertura de la Universidad Literaria de Madrid, el día 1º de noviembre de 1844 /

Enc. con los Programas de enseñanzas de la Universidad.

[La educación de los pueblos es la mejor garantía del porvenir y el áncora de los estados] : discurso inaugural pronunciado en la solemne apertura de la Universidad Literaria de Madrid ... el 1º de noviembre de 1845 /

Mode of access: Internet.

[Utilidad de las ciencias] : discurso pronunciado en la solemne inauguración de los estudios de la Universidad de Madrid el dia 1º de octubre de 1847 /

Mode of access: Internet.

Traité du choix des livres : contenant, 1. Des observations sur la nature des ouvrages les plus propres à former une collection peu considérable, mais précieuse sous le rapport du goût. 2. Des recherches littéraires sur la prédilection particulière que des hommes célèbres de tous les temps out cue pour certains ouvrages. 3. Un Mémorial bibliographique des éditions les plus correctes et les plus belles des chefs-d'uvre de la littérature sacrée, grecque, latine, française et étrangère. 4. Enfin une notice sur l'établissement d'une bibliothèque, sa construction, sa division, le soin que l'on doit prendre des livres, etc. etc /

Mode of access: Internet.

Ley de minería de 11 de abril de 1849 : reglamento para su ejecución y el del Cuerpo de Ingenieros de minas : Instrucciones para la recaudación de impuestos del ramo y demas disposiciones dictadas para el establecimiento de la ley citada y concernientes al ramo hasta 1.º de mayo de 1852.

Mode of access: Internet.

Leçons d'analyse logique : contenant 1º des préceptes dur l'art d'analyser , 2º des exercices et des sujets d'analyse logique : suivies d'un programme de questions sur la seconde partie de la nouvelle grammaire française /

Mode of access: Internet.

Nouvelle arithmétique des écoles primaires : divisee en deux parties, 1º theorie ... /

Contiene: 1º Théorie et pratique du calcul. - 2º Applications.

Discurso inaugural pronunciado para la solemne apertura del curso de 1843 a 1844 en la Universidad Literaria de esta Corte, el día 1º de noviembre último /

Mode of access: Internet.

Excerpta historica iussu Imp. Constantini Porphyrogeniti confecta.

v. 1. Excerpta de legationibus: pars. 1. Excerpta de legationibus Romanorum ad gentes. pars. 2. Excerpta de legationibus gentium ad Romanos.--v. 2., pars. 1-2. Excerpta de virtutibus et vitiis.--v. 3. Excerpta de insidiis.--v. 4. Excerpta de sententiis.

R.P. Gasparis de Ribadeneira toletani Societatis Iesu ... Tractaius de actibus humanis in genere : in 1.2. D. Thomae a quaest. 6.

Mode of access: Internet.

Análise comparativa da imunoexpressão do IMP-3 e Ki-67 em queilites actínicas e carcinoma epidermóide de lábio inferior

Epithelial changes observed in actinic cheilitis (AC) and squamous cell carcinoma of the lower lip (LLSCC) are mainly caused by chronic exposure to ultraviolet rays (UV) and are studied using different immunohistochemical markers trying to evaluate the process of carcinogenesis. The objective of this study was to comparatively evaluate the expression of Ki-67 proteins and IMP-3 in AC and LLSCC to contribute with additional information on carcinogenesis in lower lip. A total of 33 cases of AC and 33 cases of LLSCC were studied, analyzed the clinical and pathological features and immunostaining of Ki-67 and IMP-3. Immunohistochemical analysis of Ki-67 was made through the determination of the proliferation index (PI) and subsequent classification of the cases according to the scores: 0 (0% positive cells) +1 (≤30%) + 2 (> 30% and ≤60%) and +3 (> 60%). For statistical tests cases were classified as unmarked (score 0), low expression (score +1) and high expression (scores +2 and +3). For the expression of IMP-3, the percentage of immunostained epithelial cells was established, and assigned scores: 0 (corresponding to 0%), +1 (up to 30% of positive cells); +2 (From 30% to 60% of immunostained cells) and +3 (over 60% of positive cells). Statistical tests chi-square test, Mann-Whitney and Wilcoxon were used. The significance level was 5%. Most AC chaos was male (78.8%) with mean age of 50 years and cases of LLSCC also were male (69.89%) with an average of 62 years. The Ki-67 was expressed in all cases of AC and in cases of LLSCC, predominantly in the two injuries the score 2, corresponding to 81.8% of cases in ACs and 54.5% in the CELI. The expression of IMP-3 in ACs occurred in 72.7% of cases, predominantly in 36.3% of LLSCC cases score 1. Already in the IMP-3 was expressed in 60.6% of cases, especially in 27.3% of the score of the cases 3. These results allow us to conclude that the expression of IMP3 and proliferative activity are early events in carcinogenesis independently lower lip state of change.

Onvphrii Panvinii Veronensis Fratris Eremitae Avgvstiniani Fastorvm Libri V. A Romvlo Rege Vsqve Ad Imp. Caesarem Carolvm V. Avstrivm Avgustvm : Eiusdem In Fastorvm Libros Commentarii, in quis infiniti variorum auctorum loci ... partim exponuntur, partim emendantur. His Accedit Appendix In Qva Imperatorvm & Consulum ordinariorum Fasti a Caesare Dictatore usque ad Iustinianum Augustum, ab Onuphrio concinnati M. Verrii Flacci consularia & triumphalia fragmenta M. Aurelii Cassiodori, Prosperi Aquitanici, in certi auctoris, Marcellini comitis chronica

Signaturformel: *8, a-i6, A-Z8, Aa-Gg6, Hh4, a-e6, f4, g2, A8, B4-C4, D-F6, G4 (1 Bl. vacat)

Characteristics and management of Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemase in a tertiary hospital.

Background: The emergence of Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemases is rare. We report an occurrence of Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemases in a Chinese tertiary care hospital from November 2010 to December 2012. Methods: The clinical characteristics of 30 patients were described. The genetic relationship of isolates was determined by pulsed-field gel electrophoresis (PFGE). Carbapenemases were detected by modified Hodge test (MHT) and polymerase chain reactions (PCRs). Amplicons were sequenced and blasted to determine the genotype. Results: Most infected patients were from intensive care unit and had complex and serious underlying illnesses requiring mechanical ventilation. PFGE revealed that Klebsiella pneumoniae showed two major PFGE types. Two Klebsiella oxytoca had an indistinguishable PFGE pattern, while four Enterobacter cloacae were different strains. The sequencing studies showed Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemase in the 23 infected patients. The majority of patients had infections with the carbapenemase-producing Enterobacteriaceae (CPE) strain, most were successfully treated with a range of antibiotics and discharged. Conclusion: It is important to maintain a high index of suspicion to screen for carbapenemase-producing Enterobacteriaceae strains. Rapid identification of these strains and implementation of stringent procedures are the key to prevent major outbreaks in a hospital setting. Keywords:

Up-regulation Of Dnam-1 And Nkp30, Associated With Improvement Of Nk Cells Activation After Long-term Culture Of Mononuclear Cells From Patients With Ovarian Neoplasia.

This study aimed at evaluating the functional activation and activating receptors expression on resting, short- and long-term NK and NK-like T cells from blood of ovarian neoplasia patients. Blood from patients with adnexal benign alterations (n = 10) and ovarian cancer (grade I-IV n = 14) were collected after signed consent. Effector cells activation was evaluated by the expression of the CD107a molecule. Short-term culture was conducted overnight with IL-2 and long-term culture for 21 days, by a method designed to expand CD56(+) lymphocytes. Short-term culture significantly increased NK cells activation compared to resting NK cells (p<0.05), however, the long-term procedure supported an even higher increase (p<0.001). Resting NK-like T cells showed poor activation, which was not altered by the culture procedures. The long-term culture effectively increased the expression of the activating receptors on NK and NK-like T cells, either by increasing the number of cells expressing a given receptor and/or by up-regulating their expression intensity. As a conclusion, the long-term culture system employed, resulted in a high number of functional NK cells. The culture system was particularly efficient on the up-regulation of NKp30 and DNAM-1 receptors on NK cells.

Hypertrophic Adenoid Is A Major Infection Site Of Human Bocavirus 1.

Human bocavirus 1 (HBoV1) is associated with respiratory infections worldwide, mainly in children. Similar to other parvoviruses, it is believed that HBoV1 can persist for long periods of time in humans, probably through maintaining concatemers of the virus single-stranded DNA genome in the nuclei of infected cells. Recently, HBoV-1 was detected in high rates in adenoid and palatine tonsils samples from patients with chronic adenotonsillar diseases, but nothing is known about the virus replication levels in those tissues. A 3-year prospective hospital-based study was conducted to detect and quantify HBoV1 DNA and mRNAs in samples of the adenoids (AD), palatine tonsils (PT), nasopharyngeal secretions (NPS), and peripheral blood (PB) from patients undergoing tonsillectomy for tonsillar hypertrophy or recurrent tonsillitis. HBoV1 was detected in 25.3% of the AD samples, while the rates of detection in the PT, NPS, and PB samples were 7.2%, 10.5%, and 1.7%, respectively. The viral loads were higher in AD samples, and 27.3% of the patients with HBoV had mRNA detectable in this tissue. High viral loads and detectable mRNA in the AD were associated with HBoV1 detection in the other sample sites. The adenoids are an important site of HBoV1 replication and persistence in children with tonsillar hypertrophy. The adenoids contain high HBoV1 loads and are frequently positive for HBoV mRNA, and this is associated with the detection of HBoV1 in secretions.