Imagens das emoções na infância: Representações sociais da alegria e da tristeza entre crianças em idade pré-escolar

As crianças são muito sensíveis a qualquer mudança no meio familiar ou social. O modo como apreendem, vivenciam e exprimem emoções ou sentimentos, em interacção com o meio - pais, professores e colegas determina, em muito, o seu desenvolvimento, nomeadamente a nível cognitivo, emocional e social. Nesta investigação averiguámos as representações sociais dos sentimentos, em particular da alegria e da tristeza, entre crianças com 5 e 6 anos, de ambos os sexos, que frequentam Jardins de Infância em Lisboa. Enquadrámos teoricamente a investigação na teoria das Representações Sociais (e.g. Moscovici,1976). Os dados foram recolhidos através de desenhos e por associação livre de palavras, a questões colocadas individualmente às crianças, e tratados através de AFO. Os resultados revelaram bastante acerca dos sentimentos das crianças, o que também nos estimula a reflectir sobre o modo mais cuidado para actuar com elas, contribuindo para o seu bem-estar psíquico e social, e aprendizagem. ABSTRACT; Children are deeply sensitive to any change in the family or social environment. The way in which they perceive, experience, and express emotions or feelings when interacting with the environment - parents, teachers, and fellow students - largely determines their development namely on a cognitive, emotional and social level. This research examines the social representations of feelings, particularly of joy and sadness, among children aged 5 and 6 years old, of the both sexes, and attending Kindergartens in Lisbon. On a theoretical perspective, the empirical research is framed on the Social Representations theory (e.g., Moscovici,1976). The data was gathered using drawings and free association, from questions individually made to the children, and examined through FCA2. The results showed quite a lot about the feelings of the children, which also leads us to reflect on the most careful way to act with them, as to contribute to their psychic and social well being, as well as their learning

Social representations of nursing students about hospital assistance and primary health care

Objective: To analyze how social representations of hospital and community care are structured in two groups of nursing students – 1st and 4th years. Method: Qualitative research oriented by the Theory of Social Representations. We used a questionnaire with Free Association of Words. Data were analyzed in the Software IRaMuTeQ 0.6 alpha 3. Results: We applied the method of Descending Hierarchical Classifi cation and obtained four classes. Class 4 has the largest social representation (30.41%) within the corpus. The two organizational axes are nurse and disease/patient in the central core. On the periphery are the care and help related to the nurse and the treatment and prevention associated with the disease. Conclusion: Social representations focus on disease/patient and on the role of nurses in the treatment, prevention, and care. Health promotion and the social determinants of health are absent from the social representations of students.

Representações sociais acerca da AIDS e percepção de risco da infecção entre estudantes universitários

Neste estudo exploratório procurouse identificar as representações sociais que jovens universitários elaboram sobre a aids e a percepção de risco em relação à infecção pelo HIV. Utilizou-se um instrumento de evocação que se baseia na associação livre de ideias, partindo-se do termo indutor aids. Participaram da pesquisa 201 estudantes, de ambos os sexos, matriculados em diferentes cursos de uma universidade pública. Os dados foram analisados pelo programa de computação EVOC. Os resultados indicaram que os universitários construíram um saber sobre a aids ancorado no conhecimento médico-científico sobre a síndrome da imunodeficiência adquirida. Sexo, morte e doença foram as palavras mais evocadas que, junto a medo, constituem o provável núcleo organizador das representações acerca da aids. Crenças e preconceito relacionados a grupos estigmatizados e a comportamentos considerados desviantes não apareceram nas associações dos universitários. Percebem-se como vulneráveis à infecção identificando comportamentos de risco em toda a população, inclusive no grupo interno. ____________________________________________________________________________________ ABSTRACT

O VIH e a mulher: “Um olhar sobre a sexualidade feminina e suas implicações”

Dissertação de Mestrado apresentada ao Instituto Superior de Psicologia Aplicada para obtenção de grau de Mestre na especialidade de Psicologia Clínica.

O nome como lugar atribuído, concedido e sentido: Um estudo de caso sobre o transgeracional

Dissertação de Mestrado apresentada no ISPA – Instituto Universitário de Ciências Psicológicas, Sociais e da Vida para obtenção do grau de Mestre na especialidade de Psicologia Clínica.

O desejo no feminino

Dissertação de Mestrado apresentada no ISPA – Instituto Universitário para obtenção de grau de Mestre na especialidade de Psicologia Clínica

Representações sociais do envelhecimento ativo num olhar genderizado

O objetivo deste estudo é analisar as representações sociais do envelhecimento ativo, procurando detetar os impactos das conceções diferenciadas de homens e mulheres idosos. Foi desenvolvido um estudo de coorte transversal. Foram inquiridas 123 pessoas idosas (M=76,84; DP=8,46). Utilizámos para aceder às evocações sobre o envelhecimento ativo a Técnica de Associação Livre de Palavras. As representações que emergiram com maior frequência foram a “família”, “passeio”, “convívio” e “saúde”. Foi possível destacar diferenças na representação social do envelhecimento ativo a partir de um olhar genderizado. Das evocações exclusivas do sexo masculino a evocação proeminente ancora no “desporto”, enquanto no sexo feminino a “atividade doméstica” predomina. Ambos os sexos elegeram a “família” como evocação proeminente na representação social do envelhecimento ativo. As mulheres, refletindo os papéis que desempenharam ao longo da sua vida parecem assumir que um envelhecimento ativo representa a execução das tarefas que sempre fizeram, centrando-se muitas das suas evocações em conteúdos de cariz familista, onde o papel de cuidadoras se destaca. As atividades de carácter instrumental e associadas à esfera privada, como as tarefas domésticas emergem com maior proeminência. No caso dos homens, a componente familista é também evocada, emergindo concomitantemente atividades de lazer.

SOCIAL REPRESENTATIONS OF BASICS LIFE SUPPORT

Victims of cardiac arrest need immediate Basic Life Support, in order to preserve as much as possible, the flow of blood to the brain and heart and other vital organs, it is essential to gain time pending differentiated help, performing simple acts and practical (BLS) to save lives. Learn how to perform RPC is an interactive process that requires knowledge and skills, but at the same time an act of solidarity, social responsibility, civic consciousness, and a duty of citizenship. Because no one revives alone, it requires a coordinated work of a team, all citizens must join forces in a single goal: Save Lives, the massification of the BLS (RPC, 2014). We conducted an exploratory study that aimed to identify the social representations of basic life support in the general population. We used the technique of free association of words through a short questionnaire, we obtained a sample of 45 participants. The results show that participants were mostly female and 27 that fashion of age was in the age group 40 to 59 years. With regard to social representations, we find an organized structure follows the core: help, help to revive, and save is giving life, are in fact structural and consensual elements in basic life support. In more peripheral elements we find extremely important elements, which can be worked in a way so that the core is more efficient such as to act coordinately as a team in face of an accident, it can thus be successful in practice. The social representation of basic life support does not differ from that referred in the literature on the subject, but it is common knowledge that these skills can only be acquired if they are systematically trained, because they obey an algorithm that if it is not settled theoretical and instrumentally it is not effective in practice.

Comparison between computational alanine scanning and per-residue binding free energy decomposition for protein-protein association using MM-GBSA: application to the TCR-p-MHC complex.

Recognition by the T-cell receptor (TCR) of immunogenic peptides (p) presented by Class I major histocompatibility complexes (MHC) is the key event in the immune response against virus-infected cells or tumor cells. A study of the 2C TCR/SIYR/H-2K(b) system using a computational alanine scanning and a much faster binding free energy decomposition based on the Molecular Mechanics-Generalized Born Surface Area (MM-GBSA) method is presented. The results show that the TCR-p-MHC binding free energy decomposition using this approach and including entropic terms provides a detailed and reliable description of the interactions between the molecules at an atomistic level. Comparison of the decomposition results with experimentally determined activity differences for alanine mutants yields a correlation of 0.67 when the entropy is neglected and 0.72 when the entropy is taken into account. Similarly, comparison of experimental activities with variations in binding free energies determined by computational alanine scanning yields correlations of 0.72 and 0.74 when the entropy is neglected or taken into account, respectively. Some key interactions for the TCR-p-MHC binding are analyzed and some possible side chains replacements are proposed in the context of TCR protein engineering. In addition, a comparison of the two theoretical approaches for estimating the role of each side chain in the complexation is given, and a new ad hoc approach to decompose the vibrational entropy term into atomic contributions, the linear decomposition of the vibrational entropy (LDVE), is introduced. The latter allows the rapid calculation of the entropic contribution of interesting side chains to the binding. This new method is based on the idea that the most important contributions to the vibrational entropy of a molecule originate from residues that contribute most to the vibrational amplitude of the normal modes. The LDVE approach is shown to provide results very similar to those of the exact but highly computationally demanding method.

Prospective association of the SHARE-operationalized frailty phenotype with adverse health outcomes: evidence from 60+ community-dwelling Europeans living in 11 countries.

BACKGROUND: Among the many definitions of frailty, the frailty phenotype defined by Fried et al. is one of few constructs that has been repeatedly validated: first in the Cardiovascular Health Study (CHS) and subsequently in other large cohorts in the North America. In Europe, the Survey of Health, Aging and Retirement in Europe (SHARE) is a gold mine of individual, economic and health information that can provide insight into better understanding of frailty across diverse population settings. A recent adaptation of the original five CHS-frailty criteria was proposed to make use of SHARE data and measure frailty in the European population. To test the validity of the SHARE operationalized frailty phenotype, this study aims to evaluate its prospective association with adverse health outcomes. METHODS: Data are from 11,015 community-dwelling men and women aged 60+ participating in wave 1 and 2 of the Survey of Health, Aging and Retirement in Europe, a population-based survey. Multivariate logistic regression analyses were used to assess the 2-year follow up effect of SHARE-operationalized frailty phenotype on the incidence of disability (disability-free at baseline) and on worsening disability and morbidity, adjusting for age, sex, income and baseline morbidity and disability. RESULTS: At 2-year follow up, frail individuals were at increased risk for: developing mobility (OR 3.07, 95% CI, 1.02-9.36), IADL (OR 5.52, 95% CI, 3.76-8.10) and BADL (OR 5.13, 95% CI, 3.53-7.44) disability; worsening mobility (OR 2.94, 95% CI, 2.19- 3.93) IADL (OR 4.43, 95% CI, 3.19-6.15) and BADL disability (OR 4.53, 95% CI, 3.14-6.54); and worsening morbidity (OR 1.77, 95% CI, 1.35-2.32). These associations were significant even among the prefrail, but with a lower magnitude of effect. CONCLUSIONS: The SHARE-operationalized frailty phenotype is significantly associated with all tested health outcomes independent of baseline morbidity and disability in community-dwelling men and women aged 60 and older living in Europe. The robustness of results validate the use of this phenotype in the SHARE survey for future research on frailty in Europe.

Determination of CYP2D6 *3, *4, and *10 frequency in women with breast cancer in São Luís, Brazil, and its association with prognostic factors and disease-free survival

The CYP2D6 enzyme is crucial for the metabolism of tamoxifen. The CYP2D6 gene is highly polymorphic, and individuals can be extensive, intermediate, or poor tamoxifen metabolizers. The aim of this study was to determine the frequencies of the CYP2D6 *3, *4, and *10 alleles in women with breast cancer who were treated with tamoxifen and analyze the association of enzyme activity with prognostic factors and disease-free survival. We observed a high frequency of CYP2D6 *10, with an allelic frequency of 0.14 (14.4%). The *3 allele was not present in the studied population, and *4 had an allelic frequency of 0.13 (13.8%). We conclude that patients with reduced CYP2D6 activity did not present worse tumor characteristics or decreased disease-free survival than women with normal enzyme activity, as the difference was not statistically significant. We also observed a high frequency of CYP2D6 *10, which had not been previously described in this specific population. This study is the first in north-northeastern Brazil that aimed to contribute to the knowledge of the Brazilian regional profile for CYP2D6 polymorphisms and their phenotypes. These findings add to the knowledge of the distribution of different polymorphic CYP2D6 alleles and the potential role of CYP2D6 genotyping in clinical practice prior to choosing therapeutic protocols.

Inhibitory control in memory: evidence for negative priming in free recall

Cognitive control mechanisms—such as inhibition—decrease the likelihood that goal-directed activity is ceded to irrelevant events. Here, we use the action of auditory distraction to show how retrieval from episodic long-term memory is affected by competitor inhibition. Typically, a sequence of to-be-ignored spoken distracters drawn from the same semantic category as a list of visually-presented to-be-recalled items impairs free recall performance. In line with competitor inhibition theory (Anderson, 2003), free recall was worse for items on a probe trial if they were a repeat of distracter items presented during the previous, prime, trial (Experiment 1). This effect was only produced when the distracters were dominant members of the same category as the to-be-recalled items on the prime. For prime trials in which distracters were low-dominant members of the to-be-remembered item category or were unrelated to that category—and hence not strong competitors for retrieval—positive priming was found (Experiments 2 & 3). These results are discussed in terms of inhibitory approaches to negative priming and memory retrieval.