Eça de Queirós e seu texto de imprensa 'Tema para versos I e II' (02 e 03/04/1893-Gazeta de Notícias): considerações

Eça de Queirós published in Gazeta de Notícias, the text “Theme for verses I and II” in April 2nd and 3rd in 1893 . From part II, it was taken an excerpt and published as a short story under the title “The maid” when this text was a part of the book Short Stories (12 stories, some of them handwritten, from 1874 to 1897) gathered by his friend, Luís de Magalhães, and published in 1903, under the year of 1902. Since then, the text ”The maid” is present in many editons of Eça de Queirós’ short stories without any mention to its primary source, the newspaper Gazeta de Notícias (Rio de Janeiro), or even the other part of the text in which it was originally in. The objective of these short considerations is reflecting if the short story, known as “The maid”, should be read as an excerpt of the original text as it has been done since 1902, or it should be put in its original context, joining the two parts of the text “Theme for verses I and II”.

Eça de Queirós e a imprensa carioca: o suplemento literário da Gazeta de Notícias

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Eça de Queirós na Gazeta de Notícias (Rio de Janeiro): a função social do jornal

There will be a review on the collaboration of Eça de Queirós in Gazeta de Notícias (Rio de Janeiro-1880-1897), written directly to the Brazilian public. In some of these texts Eça makes reflections on the mediation that the newspaper plays in society, particularly in southern Europe. We believe that in these texts there are manifestations and traits of doctrinal-programmatic nature, metalitterary aspects and also a kind of history of occidental press. These press texts are now gathered in Textos de Imprensa IV – da Gazeta de Notícias, which includes the volume critical edition of the works of Eça de Queirós, coordinated by Carlos Reis. The study of these texts will contribute to the analysis and interpretation of his fiction and journalistic works.

Intertextualidade e paródia: Eça de Queiroz entre o passado e o presente

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Intertextualidade e paródia: Eça de Queiroz entre o passado e o presente

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Machado de Assis e Eça de Queirós: para além da polêmica...

Quando se pensa nas relações entre Machado de Assis e Eça de Queirós é comum referir-se à polêmica travada em torno da repercussão de O primo Basílio no Brasil. Obviamente, vários outros aspectos podem ser considerados quando se propõe uma reflexão sobre diálogos possíveis entre os dois grandes autores das literaturas de língua portuguesa no século XIX. O nosso objetivo aqui é discutir como a presença do clero e a relação com a religião são retratadas, sobretudo, em duas obras desses escritores: Dom Casmurro e A relíquia.

Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism

Sphingosine 1-phosphate (S1P) is a potent mitogenic signal generated from sphingosine by the action of sphingosine kinases (SKs). In this study, we show that in the human arterial endothelial cell line EA.hy 926 histamine induces a time-dependent upregulation of the SK-1 mRNA and protein expression which is followed by increased SK-1 activity. A similar upregulation of SK-1 is also observed with the direct protein kinase C activator 12-O-tetradecanoylphorbol-13-acetate (TPA). In contrast, SK-2 activity is not affected by neither histamine nor TPA. The increased SK-1 protein expression is due to stimulated de novo synthesis since cycloheximide inhibited the delayed SK-1 protein upregulation. Moreover, the increased SK-1 mRNA expression results from an increased promoter activation by histamine and TPA. In mechanistic terms, the transcriptional upregulation of SK-1 is dependent on PKC and the extracellular signal-regulated protein kinase (ERK) cascade since staurosporine and the MEK inhibitor U0126 abolish the TPA-induced SK-1 induction. Furthermore, the histamine effect is abolished by the H1-receptor antagonist diphenhydramine, but not by the H2-receptor antagonist cimetidine. Parallel to the induction of SK-1, histamine and TPA stimulate an increased migration of endothelial cells, which is prevented by depletion of the SK-1 by small interfering RNA (siRNA). To appoint this specific cell response to a specific PKC isoenzyme, siRNA of PKC-alpha, -delta, and -epsilon were used to selectively downregulate the respective isoforms. Interestingly, only depletion of PKC-alpha leads to a complete loss of TPA- and histamine-triggered SK-1 induction and cell migration. In summary, these data show that PKC-alpha activation in endothelial cells by histamine-activated H1-receptors, or by direct PKC activators leads to a sustained upregulation of the SK-1 protein expression and activity which, in turn, is critically involved in the mechanism of endothelial cell migration.

Rabbinismus enucleatus : quo ad ea, quæ Ebræo-Chaldæis vel prorsus non, vel minus usitata sunt : præmissa directione legendi Scripturam absque punctis

Ioh. Andr. Danz

Maḥazē mekîrat Yôsēf : ein ṭeaṭer šṭik in 7 akṭin un in 17 szenen ; giformirṭ noch di besṭe un gleichsṭe deos fun gemore ...

fun Eljakim Tzunzer

Moris Shṿarts un der Idisher ḳunsṭ ṭeaṭer

A. H. Bialin