979 resultados para Devis quasi-expérimental
Resumo:
Many regional governments in developed countries design programs to improve the competitiveness of local firms. In this paper, we evaluate the effectiveness of public programs whose aim is to enhance the performance of firms located in Catalonia (Spain). We compare the performance of publicly subsidised companies (treated) with that of similar, but unsubsidised companies (non-treated). We use the Propensity Score Matching (PSM) methodology to construct a control group which, with respect to its observable characteristics, is as similar as possible to the treated group, and that allows us to identify firms which retain the same propensity to receive public subsidies. Once a valid comparison group has been established, we compare the respective performance of each firm. As a result, we find that recipient firms, on average, change their business practices, improve their performance, and increase their value added as a direct result of public subsidy programs.
Resumo:
Many regional governments in developed countries design programs to improve the competitiveness of local firms. In this paper, we evaluate the effectiveness of public programs whose aim is to enhance the performance of firms located in Catalonia (Spain). We compare the performance of publicly subsidised companies (treated) with that of similar, but unsubsidised companies (non-treated). We use the Propensity Score Matching (PSM) methodology to construct a control group which, with respect to its observable characteristics, is as similar as possible to the treated group, and that allows us to identify firms which retain the same propensity to receive public subsidies. Once a valid comparison group has been established, we compare the respective performance of each firm. As a result, we find that recipient firms, on average, change their business practices, improve their performance, and increase their value added as a direct result of public subsidy programs.
Resumo:
OBJECTIVES: To show the effectiveness of a brief group alcohol intervention. Aims of the intervention were to reduce the frequency of heavy drinking occasions, maximum number of drinks on an occasion and overall weekly consumption. METHODS: A cluster quasi-randomized control trial (intervention n = 338; control n = 330) among 16- to 18-year-old secondary school students in the Swiss Canton of Zürich. Groups homogeneous for heavy drinking occasions (5+/4+ drinks for men/women) consisted of those having medium risk (3-4) or high risk (5+) occasions in the past 30 days. Groups of 8-10 individuals received two 45-min sessions based on motivational interviewing techniques. RESULTS: Borderline significant beneficial effects (p < 0.10) on heavy drinking occasions and alcohol volume were found 6 months later for the medium-risk group only, but not for the high-risk group. None of the effects remained significant after Bonferroni corrections. CONCLUSIONS: Group intervention was ineffective for all at-risk users. The heaviest drinkers may need more intensive treatment. Alternative explanations were iatrogenic effects among the heaviest drinkers, assessment reactivity, or reduction of social desirability bias at follow-up through peer feedback.
Resumo:
L'athérosclérose (ATS) est une maladie artérielle inflammatoire chronique à l'origine des nombreuses maladies cardiovasculaires que sont l'infarctus du myocarde, l'accident vasculaire cérébral ou encore l'artériopathie oblitérante des membres inférieurs. L'ATS se définit comme la formation de plaques fibro-lipidiques dans l'intima des artères. Les facteurs de risque majeurs associés à l'ATS sont l'hypertension, l'hypercholestérolémie, le tabagisme, le diabète, la sédentarité, ou encore des prédispositions génétiques. L'ATS peut être asymptomatique durant des années ou alors engendrer des complications aiguës pouvant parfois mettre le pronostic vital en jeu. Les complications les plus graves surviennent principalement lors de la rupture d'une plaque athéromateuse dite vulnérable ou instable. En effet, cette dernière peut se rompre et entraîner la formation d'un thrombus artériel occlusif avec, pour conséquence, l'ischémie/nécrose des tissus en aval. Prévenir le développement de la plaque vulnérable et/ou la « stabiliser » permettrait donc de prévenir les complications cliniques de l'ATS. Cet objectif requiert une connaissance éclairée des mécanismes cellulaires et moléculaires impliqués dans la physiopathologie de l'ATS et de la plaque vulnérable. Les travaux expérimentaux menés au sein du laboratoire du service d'angiologie du CHUV sous la direction du Prof. Lucia Mazzolai ont montré que l'angiotensine II (ang II), produit final de la cascade du système rénine-angiotensine, joue un rôle majeur dans la « vulnérabilité » des plaques athéromateuses (1). Ces travaux ont été réalisés à partir d'un modèle animal original développant des plaques d'ATS vulnérables dépendantes de l'ang II: la souris ApoE-/- 2 reins-1 clip (2K1C). Plus récemment, le laboratoire d'angiologie a mis en évidence une implication directe des leucocytes, plus précisément des macrophages et des lymphocytes T CD4+, dans l'athérogenèse ang II-dépendante (2,3). Dernièrement, des travaux ont également suggéré un rôle possible des granulocytes neutrophiles dans l'ATS (4,5,6,7). Toutefois, les études sont encore limitées de sorte que le rôle exact des neutrophiles dans l'ATS et plus spécialement dans l'ATS induite par l'ang II reste à démontrer. Une des recherches actuelles menée dans le laboratoire est donc d'étudier le rôle des neutrophiles dans le développement de la plaque athéromateuse vulnérable à partir du modèle animal, la souris ApoE-/- 2K1C. Pour évaluer le rôle direct des neutrophiles chez notre modèle animal, nous avons choisi comme méthode la déplétion des neutrophiles circulants par l'utilisation d'un anticorps spécifique. Il a été reporté dans la littérature que l'anticorps monoclonal NIMP-R14 3 permettait de dépléter sélectivement in vivo les neutrophiles dans différents modèles murins (8,9). Cependant, ces études ont utilisé cet anticorps anti-neutrophiles majoritairement sur des périodes expérimentales de durées relativement limitées (12-14 jours) et la question s'est donc posée de savoir si cet anticorps pouvait aussi dépléter les neutrophiles chez notre modèle animal, qui requiert une période expérimentale de 4 semaines pour développer des plaques vulnérables (1). Le but de ce travail a donc été de produire l'anticorps NIMP-R14 et d'évaluer son efficacité chez la souris ApoE-/- 2K1C qui développe des plaque d'ATS vulnérables dépendantes de l'ang II.
Resumo:
Experimental quasi-two-dimensional Zn electrodeposits are grown under forced convection conditions. Large-scale effects, with preferential growth towards the impinging flow, together with small-scale roughness suppression effects are evidenced and separately analyzed by using two different radial cell configurations. Interpretations are given in terms of primary concepts concerning current and concentration distributions.
Resumo:
Using the experimental data of Paret and Tabeling [Phys. Rev. Lett. 79, 4162 (1997)] we consider in detail the dispersion of particle pairs by a two-dimensional turbulent flow and its relation to the kinematic properties of the velocity field. We show that the mean square separation of a pair of particles is governed by rather rare, extreme events and that the majority of initially close pairs are not dispersed by the flow. Another manifestation of the same effect is the fact that the dispersion of an initially dense cluster is not the result of homogeneously spreading the particles within the whole system. Instead it proceeds through a splitting into smaller but also dense clusters. The statistical nature of this effect is discussed.
Resumo:
Dynamic morphological transitions in thin-layer electrodeposits obtained from copper sulphate solutions have been studied. The chemical composition of the electrodeposits indicates that they appear as a consequence of the competition between copper and cuprous oxide formation. In addition, the Ohmic control of the process is verified at initial stages of the deposit growth. At higher deposit developments, gravity-induced convection currents play a role in the control of the whole process and affect the position of these transitions.
Resumo:
The influence of an inert electrolyte (sodium sulfate) on quasi-two-dimensional copper electrodeposition from a nondeaerated aqueous copper sulfate solution has been analyzed. The different morphologies for a fixed concentration of CuSO4 have been classified in a diagram in terms of the applied potential and the inert electrolyte concentration. The main conclusion is the extension of the well-known Ohmic model for the homogeneous growth regime for copper sulfate solutions with small amounts of sodium sulfate. Moreover, we have observed the formation of fingerlike deposits at large applied potential and inert electrolyte concentration values, before hydrogen evolution becomes the main electrode reaction.
Resumo:
En el presente trabajo se lleva a cabo una revisión histórica de los estudios realizados sobre el bilingiiismo, concretándose, fundamentalmente, en las dos grandes hipótesis teóricas en torno al mismo. Se analizan, a continuación, las investigaciones que apoyan tanto a la hipótesis de "sistemas lingiiisticos separados" como a la hipótesis de un "único sistema". Por último se hace una presentación de los trabajos que han sido más relevantes en la investigación actual. De esta forma se presentan los estudios de carácter psicofisiológico, la relación entre bilingiiismo y psicologia cognitiva, la medición del bilingüismo y la teoria del código dual aplicado al bilingüismo. El texto termina planteando una serie de consideraciones de carácter metodológico y la propuesta de un modelo que va a ser objeto de un segundo escrito sobre dicha temática.
Resumo:
En el presente trabajo se lleva a cabo una revisión histórica de los estudios realizados sobre el bilingiiismo, concretándose, fundamentalmente, en las dos grandes hipótesis teóricas en torno al mismo. Se analizan, a continuación, las investigaciones que apoyan tanto a la hipótesis de "sistemas lingiiisticos separados" como a la hipótesis de un "único sistema". Por último se hace una presentación de los trabajos que han sido más relevantes en la investigación actual. De esta forma se presentan los estudios de carácter psicofisiológico, la relación entre bilingiiismo y psicologia cognitiva, la medición del bilingüismo y la teoria del código dual aplicado al bilingüismo. El texto termina planteando una serie de consideraciones de carácter metodológico y la propuesta de un modelo que va a ser objeto de un segundo escrito sobre dicha temática.
Resumo:
We study the response of regional employment and nominal wages to trade liberalization, exploiting the natural experiment provided by the opening of Central and Eastern European markets after the fall of the Iron Curtain in 1990. Using data for Austrian municipalities, we examine di¤erential pre- and post-1990 wage and employment growth rates between regions bordering the formerly communist economies and interior regions. If the 'border regions'are de...ned narrowly, within a band of less than 50 kilometers, we can identify statistically signi...cant liberalization e¤ects on both employment and wages. While wages responded earlier than employment, the employment e¤ect over the entire adjustment period is estimated to be around three times as large as the wage e¤ect. The implied slope of the regional labor supply curve can be replicated in an economic geography model that features obstacles to labor migration due to immobile housing and to heterogeneous locational preferences.
Resumo:
An e cient procedure for the blind inversion of a nonlinear Wiener system is proposed. We proved that the problem can be expressed as a problem of blind source separation in nonlinear mixtures, for which a solution has been recently proposed. Based on a quasi-nonparametric relative gradient descent, the proposed algorithm can perform e ciently even in the presence of hard distortions.