Revision of the game laws : a letter from the Earl of Malmesbury to the Right Hon. Sir George Grey. -

Mode of access: Internet.

Earl Grey memorial lecture.

Lectures for 1919-1937 delivered at Armstrong College, University of Durham; later lectures delivered at King's College, University of Durham.

The attack upon the University of Oxford : in a letter to Earl Grey /

Author's presentation copy.

Repeal of the Union : report of the debate in the House of Commons, on Mr. O'Connell's motion : and the proceedings in the House of Lords on Earl Grey's motion for concurring in the address of the Commons : April 1834.

Mode of access: Internet.

Cerebellar grey-matter deficits, cannabis use and first-episode schizophrenia in adolescents and young adults

Epidemiological data link adolescent cannabis use to psychosis and schizophrenia, but its contribution to schizophrenia neuropathology remains controversial. First-episode schizophrenia (FES) patients show regional cerebral grey- and white-matter changes as well as a distinct pattern of regional grey-matter loss in the vermis of the cerebellum. The cerebellum possesses a high density of cannabinoid type 1 receptors involved in the neuronal diversification of the developing brain. Cannabis abuse may interfere with this process during adolescent brain maturation leading to ‘schizophrenia-like’ cerebellar pathology. Magnetic resonance imaging and cortical pattern matching techniques were used to investigate cerebellar grey and white matter in FES patients with and without a history of cannabis use and non-psychiatric cannabis users. In the latter group we found lifetime dose-dependent regional reduction of grey matter in the right cerebellar lobules and a tendency for more profound grey-matter reduction in lobule III with younger age at onset of cannabis use. The overall regional grey-matter differences in cannabis users were within the normal variability of grey-matter distribution. By contrast, FES subjects had lower total cerebellar grey-matter : total cerebellar volume ratio and marked grey-matter loss in the vermis, pedunculi, flocculi and lobules compared to pair-wise matched healthy control subjects. This pattern and degree of grey-matter loss did not differ from age-matched FES subjects with comorbid cannabis use. Our findings indicate small dose-dependent effects of juvenile cannabis use on cerebellar neuropathology but no evidence of an additional effect of cannabis use on FES cerebellar grey-matter pathology.

Cerebellar grey matter deficits in first-episode schizophrenia mapped using cortical pattern matching

Cerebellar dysfunction has been proposed to lead to “cognitive dysmetria” in schizophrenia via the cortico-cerebellar-thalamic-cortical circuit, contributing to a range of cognitive and clinical symptoms of the disorder. Here we investigated total cerebellar grey and white matter volumes and cerebellar regional grey matter abnormalities in 13 remitted first-episode schizophrenia patients with less than 2 years’ duration of illness. Patient data were compared to 13 pair-wise age, gender, and handedness-matched healthy volunteers using cortical pattern averaging on high-resolution magnetic resonance images. Total cerebellar volume and total grey matter volumes in first-episode schizophrenia patients did not differ from healthy control subjects, but total cerebellar white matter was increased and total grey to white matter ratios were reduced in patients. Four clusters of cerebellar grey matter reduction were identified: (i) in superior vermis; (ii) in the left lobuli VI; (iii) in right-inferior lobule IX, extending into left lobule IX; and (iv) bilaterally in the areas of lobuli III, peduncle and left flocculus. Grey matter deficits were particularly prominent in right lobuli III and IX, left flocculus and bilateral pedunculi. These cerebellar areas have been implicated in attention control, emotional regulation, social functioning, initiation of smooth pursuit eye movements, eye-blink conditioning, language processing, verbal memory, executive function and the processing of spatial and emotional information. Consistent with common clinical, cognitive, and pathophysiological signs of established illness, our findings demonstrate cerebellar pathology as early as in first-episode schizophrenia.

Distribution and status of the Red Squirrel (Sciurus vulgaris) and Grey Squirrel (Sciurus carolinensis) in Ireland

The distributions of the Red and Grey Squirrel were surveyed in Northern Ireland and the Republic of Ireland between 1994 and 1996. Survey methods differed between the two studies. In the former, all suitable habitat, of at least 15 ha, was inspected for species presence or absence. In the Republic, data were gathered through questionnaires to governmental and independent wildlife bodies. The combined results indicate that the Red Squirrel remains widespread and locally abundant, and is present in all but two counties. The Grey Squirrel is now more widespread than ever before, and can be found in 22 of the 32 counties. Its range expansion has varied from 0 km/yr to an estimated 13.4 km/yr, as various geographical features, principally rivers, have hindered its progress in certain directions.

Cognitive performance is related to cortical grey matter volumes in early stages of schizophrenia: A population-based study of first-episode psychosis

Background: Neuropsychological deficits have been reported in association with first-episode psychosis (FEP). Reductions in grey matter (GM) volumes have been documented in FEP subjects compared to healthy controls. However, the possible inter-relationship between the findings of those two lines of research has been scarcely investigated.

Objective: To investigate the relationship between neuropsychological deficits and GM volume abnormalities in a population-based sample of FEP patients compared to healthy controls from the same geographical area.

Methods: FEP patients (n = 88) and control subjects (n = 86) were evaluated by neuropsychological assessment (Controlled Oral Word Association Test, forward and backward digit span tests) and magnetic resonance imaging using voxel-based morphometry.

Results: Single-group analyses showed that prefrontal and temporo-parietal GM volumes correlated significantly (p < 0.05, corrected) with cognitive performance in FEP patients. A similar pattern of direct correlations between neocortical GM volumes and cognitive impairment was seen in the schizophrenia subgroup (n = 48). In the control group, cognitive performance was directly correlated with GM volume in the right dorsal anterior cingulate cortex and inversely correlated with parahippocampal gyral volumes bilaterally. Interaction analyses with "group status" as a predictor variable showed significantly greater positive correlation within the left inferior prefrontal cortex (BA46) in the FEP group relative to controls, and significantly greater negative correlation within the left parahippocampal gyrus in the control group relative to FEP patients.

Conclusion: Our results indicate that cognitive deficits are directly related to brain volume abnormalities in frontal and temporo-parietal cortices in FEP subjects, most specifically in inferior portions of the dorsolateral prefrontal cortex. (C) 2009 Elsevier B.V. All rights reserved.

Stalin: From Grey Blur to Great Terror.

Este libro desarrolla conocimientos básicos de historia para aprobar los exámenes de AS/A de enseñanza secundaria. Los temas del libro son: ¿Quién fue Stalin?, después de Lenin ¿Porqué Stalin?, los últimos años de Lenin, Stalin, Trotsky y la oposición de izquierdas, la ruptura de Stalin con la oposición de derechas, la economía estalinista: ¿un medio de control?, la necesidad de industrialización, colectivización: el dominio de los campesinos, defendiendo cambios en el poder, consolidando el poder, las vidas secretas del Kremlin, la propaganda estalinista: ¿hubo alguna verdad detrás de las mentiras?.

Thermoregulation by an Australian murine rodent, the ash-grey mouse (Pseudomys albocinereus)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

In scarlet and grey : stories of soldiers and others /

Wolff, R.L. 19th cent. fiction,

Anne Grey. A novel.

Edited by Thomas Henry Lister.

Vivian Grey.

Mode of access: Internet.

Young England, being Vivian Grey, Coningsby, Sybil, Tancred,

Includes reproductions of original title-pages.

Food habits of the world's grey wolves

Grey wolves Canis lupus have been studied extensively, but there has been no detailed review of the species' feeding ecology, despite growing debate about how to conserve wolf populations while limiting their impacts on wild or domestic ungulates. Here, we assess the extent to which the grey wolf diet varies among and within North America, Europe, and Asia. We derived dietary data from searches of published literature. We grouped studies based on their bioregional location. We compared grey wolf diet among locations using non-metric multidimensional scaling and analysis of similarity. We assessed whether increased human impacts are associated with decreased grey wolf dietary diversity. Finally, using studies from southern Europe, we assessed whether the importance of wild ungulates in grey wolf diet has increased over time, coincident with a decline in domestic species in grey wolf diet over time. We compiled dietary data from 177 studies incorporating 94607 scat and stomach samples. Grey wolf diet was dominated by large (240-650 kg) and medium-sized (23-130 kg) wild ungulates, but variation in the percentages of wild ungulates consumed, along with variation in the percentages of domestic and smaller prey species consumed, contributed to the dietary differences found among and within continents. We found no evidence that grey wolf dietary diversity varies globally, although the results from southern Europe suggest that grey wolves may switch their diets away from domestic species if more wild ungulates are available. The diversity of prey consumed by grey wolves shows that the species is capable of surviving dramatic anthropogenic upheaval. However, there is an urgent need to increase our understanding of grey wolf foraging ecology in human-dominated landscapes, in order to determine whether restoration of depleted prey populations, coupled with effective damage-prevention measures, will reduce human-wolf conflicts.