Stent-assisted coiling of bifurcation aneurysms may improve endovascular treatment: a critical evaluation in an experimental model.

BACKGROUND AND PURPOSE: Endovascular treatment of wide-neck bifurcation aneurysms often results in incomplete occlusion or aneurysm recurrence. The goals of this study were to compare results of coil embolization with or without the assistance of self-expandable stents and to examine how stents may influence neointima formation. MATERIALS AND METHODS: Wide-neck bifurcation aneurysms were constructed in 24 animals and, after 4-6 weeks, were randomly allocated to 1 of 5 groups: 1) coil embolization using the assistance of 1 braided stent (n = 5); 2) coil embolization using the assistance of 2 braided stents in a Y configuration (n = 5); 3) coil embolization without stent assistance (n = 6); 4) Y-stenting alone (n = 4); and 5) untreated controls (n = 4). Angiographic results were compared at baseline and at 12 weeks, by using an ordinal scale. Neointima formation at the neck at 12 weeks was compared among groups by using a semiquantitative grading scale. Bench studies were performed to assess stent porosities. RESULTS: Initial angiographic results were improved with single stent-assisted coiling compared with simple coiling (P = .013). Angiographic results at 12 weeks were improved with any stent assistance (P = .014). Neointimal closure of the aneurysm neck was similar with or without stent assistance (P = .908), with neointima covering coil loops but rarely stent struts. Y-stent placement alone had no therapeutic effect. Bench studies showed that porosities can be decreased with stent compaction, but a relatively stable porous transition zone was a limiting factor. CONCLUSIONS: Stent-assisted coiling may improve results of embolization by allowing more complete initial coiling, but these high-porosity stents did not provide a scaffold for more complete neointimal closure of aneurysms.

Yrityksen suorituskyvyn mittaaminen hävikin hallinnassa makeisteollisuudessa

Yritysten toimintaympäristössä on tapahtunut viime vuosina suuria muutoksia ja niitä tapahtuu tulevaisuudessakin yhä nopeammassa tahdissa. Yritysten on kehitettävä suorituskykyään, jotta sidosryhmien tarpeet kyetään tyydyttämään. Suorituskyvyn kehittäminen perustuu mittaustuloksiin ja niistä tehtäviin johtopäätöksiin. Hävikin mittaaminen ja analysointi on osa yrityksen suorituskykyä. Mittarit, joita käytetään suorituskyvyn mittaamiseen, tulee olla luotettavia. Mittaustuloksia tulee pystyä hyödyntämään tehokkaasti. Makeisteollisuudessa hävikkimärät ovat jatkuvasti kasvaneet. Tämä oli heräte tälle tutkimukselle yrittää löytää paras tapa mitata hävikkiä. Toinen tavoite oli selvittää, kuinka olisi mahdollista vähentää hävikin syntymistä. Näiden tavoitteiden saavuttaminen vaati selvitystä, kuinka hävikkiä mitataan tänä päivänä, mistä hävikki syntyy ja kuinka siihen reagoidaan. Tutkimuksessa mukana olevassa yrityksessä on laaja valikoima erilaisia makeistuotteita, sokerimakeisia ja suklaatuotteita. Tähän tutkimukseen valittiin saman tyyppiset valmistuslinjat jokaiselta tehtaalta. Näiltä linjoilta valittiin tutkittavaksi kaksi erilaista tuotetta. Tämän tutkimuksen tulos oli, että hävikkiä käsitellään jamitataan hyvin eri tavalla jokaisella tehtaalla. Hävikkiä mitataan juuri, kutenkirjallisuudessa on mainittu verraten myyntiin tai valmistettuihin kiloihin. Näin ollen ei ollut tarvetta muuttaa mittausmenetelmää, joka oli tutkimuksen päätavoite. Tärkeintä oli löytää kohdat, joissa hävikkiä syntyy. Ajan puutteen vuoksiei ollut mahdollista selvittää kaikkia hävikin syntyyn vaikuttavia syitä tai paikkoja, joissa hävikkiä syntyy. Suurin syy hävikkiin on huono laatu. Tähän syynäon osaamisen ja koulutuksen puute. Syynä hävikin syntyyn voi olla myös raaka-aineissa tai resepteissä. Tässä tutkimuksessa käytettiin Bill Crosbyn kirjaa 'Laatu on ilmaista'. Kirjassa käsitellään -14 kohdan ohjelmaa', joka voisi olla hyvä ohjelma nostaa tuotteiden laatutasoa myös tutkimuksessa mukana olevassa yrityksessä.On tärkeää tarkentaa säännöt, kuinka kirjataan hävikkiä, tarkistaa reseptit ja koulutuksen avulla nostaa osaamisen tasoa. Tällaiselle projektille täytyy olla koko organisaation ja ylimmän johdon tuki. Kaikki ne miljoonat eurot, jotka heitetään pois, voisivat olla tuloksessa. Se ei tapahdu yhdessä yössä, vaan vaatiijatkuvaa työtä tavoitteen saavuttamiseen.

How women and men project their gender prototypes on leader prototypes.

Both role incongruency theory (Eagly & Karau, 2002) and the lack of fit model by Heilman (1983) suggest that the underrepresentation of women in leadership positions can be explained by the male-typedness of leader prototypes. We examine how women and men project their gender prototypes onto leader prototypes. We found initially that men more so than women projected their gender prototypes on leader prototypes. For men there is more of an overlap between a prototypical men and a prototypical leader than there is an overlap between a prototypical woman and a prototypical leader. Women, however, do not engage in so called relative ingroup projection. In the current study, we further decompose this finding asking whether the gender difference in relative ingroup projection on leadership prototypes is driven by female prototypes, male prototypes, and/or leader prototypes. We further examine to what extent this gender difference is more manifested on positively valenced or negatively valenced attributes of prototypes. Our findings show that, while women and men have similar prototypes of leaders and men on both positively and negatively valenced attributes, men relative to women have less favorable prototypes of women but only on positively valenced attributes. An interesting implication is that efforts to address gender differences in the projection of gender prototypes onto leader prototypes should focus less on leader prototypes and more on the female prototypes. Theoretically, our findings allude to the importance of distinguishing between more subtle (evaluating the outgroup less positively on positive properties) and less subtle forms (evaluating the outgroup more negatively on negative properties) of outgroup derogation.

THE APPLICATION OF AUTOMATED CORRELATION OPTIMIZED WARPING TO THE QUALITY EVALUATION OF Radix Puerariae thomsonii: CORRECTING RETENTION TIME SHIFT IN THE CHROMATOGRAPHIC FINGERPRINTS

The application of automated correlation optimized warping (ACOW) to the correction of retention time shift in the chromatographic fingerprints of Radix Puerariae thomsonii (RPT) was investigated. Twenty-seven samples were extracted from 9 batches of RPT products. The fingerprints of the 27 samples were established by the HPLC method. Because there is a retention time shift in the established fingerprints, the quality of these samples cannot be correctly evaluated by using similarity estimation and principal component analysis (PCA). Thus, the ACOW method was used to align these fingerprints. In the ACOW procedure, the warping parameters, which have a significant influence on the alignment result, were optimized by an automated algorithm. After correcting the retention time shift, the quality of these RPT samples was correctly evaluated by similarity estimation and PCA. It is demonstrated that ACOW is a practical method for aligning the chromatographic fingerprints of RPT. The combination of ACOW, similarity estimation, and PCA is shown to be a promising method for evaluating the quality of Traditional Chinese Medicine.

PREDICTING THE BOILING POINT OF PCDD/Fs BY THE QSPR METHOD BASED ON THE MOLECULAR DISTANCE-EDGE VECTOR INDEX

The quantitative structure property relationship (QSPR) for the boiling point (Tb) of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) was investigated. The molecular distance-edge vector (MDEV) index was used as the structural descriptor. The quantitative relationship between the MDEV index and Tb was modeled by using multivariate linear regression (MLR) and artificial neural network (ANN), respectively. Leave-one-out cross validation and external validation were carried out to assess the prediction performance of the models developed. For the MLR method, the prediction root mean square relative error (RMSRE) of leave-one-out cross validation and external validation was 1.77 and 1.23, respectively. For the ANN method, the prediction RMSRE of leave-one-out cross validation and external validation was 1.65 and 1.16, respectively. A quantitative relationship between the MDEV index and Tb of PCDD/Fs was demonstrated. Both MLR and ANN are practicable for modeling this relationship. The MLR model and ANN model developed can be used to predict the Tb of PCDD/Fs. Thus, the Tb of each PCDD/F was predicted by the developed models.

Avaliação do módulo de elasticidade da madeira com uso de método não-destrutivo de vibração transversal

Numerosas pesquisas têm estudado os métodos não-destrutivos de avaliação de materiais e sua aplicação àqueles de matrizes complexas, como é o caso da madeira. Um dos primeiros métodos não-destrutivos investigados para aplicação nesses casos foi o da vibração transversal. Apesar de sua concepção simples, e a despeito dos grandes avanços obtidos nessa área com outros métodos, como, por exemplo, o ultra-som, o método de vibração transversal para a determinação do módulo de elasticidade da madeira revela-se como de grande potencial de aplicação, sobretudo pela precisão do modelo matemático a ele associado e pela possibilidade de sua aplicação a peças de dimensões estruturais (in-grade testing). Neste trabalho, apresenta-se o uso desse método na determinação do módulo de elasticidade de três espécies de eucalipto. Foram ensaiados não-destrutivamente e por ensaios mecânicos convencionais de flexão corpos-de-prova de 2 cm x 2 cm x 46 cm de E. grandis, E. saligna e E. citriodora. Os ensaios não-destrutivos foram conduzidos com uso do sistema BING - Beam Identification by Non-destructive Grading, que permite a análise das vibrações do material nos domínios do tempo e da freqüência. Os resultados obtidos revelaram boa correlação entre os dois tipos de ensaios empregados, justificando o início dos ensaios com peças de dimensões estruturais, para a viabilização da técnica nas práticas de classificação estrutural.

Taurine inhibits serum deprivation-induced osteoblast apoptosis via the taurine transporter/ERK signaling pathway

Taurine has positive effects on bone metabolism. However, the effects of taurine on osteoblast apoptosis in vitro have not been reported. The aim of this study was to investigate the activity of taurine on apoptosis of mouse osteoblastic MC3T3-E1 cells. The data showed that 1, 5, 10, or 20 mM taurine resulted in 16.7, 34.2, 66.9, or 63.75% reduction of MC3T3-E1 cell apoptosis induced by the serum deprivation (serum-free α-MEM), respectively. Taurine (1, 5, or 10 mM) also reduced cytochrome c release and inhibited activation of caspase-3 and -9, which were measured using fluorogenic substrates for caspase-3/caspase-9, in serum-deprived MC3T3-E1 cells. Furthermore, taurine (10 mM) induced extracellular signal-regulated kinase (ERK) phosphorylation in MC3T3-E1 cells. Knockdown of the taurine transporter (TAUT) or treatment with the ERK-specific inhibitor PD98059 (10 μM) blocked the activation of ERK induced by taurine (10 mM) and abolished the anti-apoptotic effect of taurine (10 mM) in MC3T3-E1 cells. The present results demonstrate for the first time that taurine inhibits serum deprivation-induced osteoblast apoptosis via the TAUT/ERK signaling pathway.

Effect of thymosin alpha-1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro

Thymosin alpha 1 (Tα1) has been shown to have beneficial effects on numerous immune system parameters, but little is known about the effects of Tα1 on patients with gastric carcinoma. The objective of this study was to determine the effect of Tα1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro, and to evaluate its efficacy as an immunoregulatory factor in patients with gastric carcinoma. We compared the effect of Tα1 on the frequency of CD4+ and CD8+ T cells, especially the CD4+CD25+Foxp3+ Tregs in peripheral blood mononuclear cells (PBMCs) from gastric carcinoma patients (N = 35) and healthy donors (N = 22). We also analyzed the changes in the proliferation of PBMCs in response to treatment with Tα1, and examined the production of Th1, Th2, and Th17 cytokines by PBMCs and tumor-infiltrating lymphocytes. The treatment of PBMCs from gastric cancer patients, with Tα1 (50 µg/mL) alone increased the percentage of CD4+CD25+Foxp3+ (suppressive antitumor-specific Tregs) from 1.68 ± 0.697 to 2.19 ± 0.795% (P < 0.05). Our results indicate that Tα1 increases the percentage of Tregs and IL-1β, TNF-α, and IL-6 in vitro.

Cultivation and identification of colon cancer stem cell-derived spheres from the Colo205 cell line

Our group established a method to culture spheres under serum-free culture condition. However, the biological characteristics and the tumorigenicity of spheres are unknown. Here, we demonstrate that sphere cells expressed high levels of the putative colorectal cancer stem cell markers CD133 and CD44. The CD133-positive rates were 13.27 ± 5.62, 52.71 ± 16.97 and 16.47 ± 2.45% in sphere cells, regular Colo205 cells and differentiated sphere cells, respectively, while the CD44-positive rates were 62.92 ± 8.38, 79.06 ± 12.10 and 47.80 ± 2.5%, respectively, and the CD133/CD44-double-positive rates were 10.77 ± 4.96, 46.89 ± 19.17 and 12.41 ± 2.27%, respectively (P < 0.05). Cancer sphere cells formed crypt-like structures in 3-D culture. Moreover, cells from cancer spheres exhibited more tumorigenicity than regular Colo205 cells in a xenograft assay. The cancer sphere cells displayed much higher oncogenicity than regular Colo205 cells to initiate neoplasms, as assayed by H&E staining, Musashi-1 staining and electron microscopy. Our findings indicated that the sphere cells were enriched with cancer stem cells (CSCs), and exhibited more proliferation capacity, more differentiation potential and especially more tumorigenicity than regular Colo205 cells in vitro and in vivo. Further isolation and characterization of these CSCs may provide new insights for novel therapeutic targets and prognostic markers.

PPM1B and P-IKKβ expression levels correlated inversely with rat gastrocnemius atrophy after denervation

Activated inhibitor of nuclear factor-κB kinase β (IKKβ) is necessary and sufficient for denervated skeletal muscle atrophy. Although several studies have shown that Mg2+/Mn2+-dependent protein phosphatase 1B (PPM1B) inactivated IKKβ, few studies have investigated the role of PPM1B in denervated skeletal muscle. In this study, we aim to explore the expression and significance of PPM1B and phosphorylated IKKβ (P-IKKβ) during atrophy of the denervated gastrocnemius. Thirty young adult female Wistar rats were subjected to right sciatic nerve transection and were sacrificed at 0 (control), 2, 7, 14, and 28 days after denervation surgery. The gastrocnemius was removed from both the denervated and the contralateral limb. The muscle wet weight ratio was calculated as the ratio of the wet weight of the denervated gastrocnemius to that of the contralateral gastrocnemius. RT-PCR and Western blot analysis showed that mRNA and protein levels of PPM1B were significantly lower than those of the control group at different times after the initiation of denervation, while P-IKKβ showed the opposite trends. PPM1B protein expression persistently decreased while P-IKKβ expression persistently increased for 28 days after denervation. PPM1B expression correlated negatively with P-IKKβ expression by the Spearman test, whereas decreasing PPM1B expression correlated positively with the muscle wet weight ratio. The expression levels of PPM1B and P-IKKβ were closely associated with atrophy in skeletal denervated muscle. These results suggest that PPM1B and P-IKKβ could be markers in skeletal muscle atrophy.

Influence of multi-phase phenomena on semibatch crystallization processes of aqueous solutions

Crystal properties, product quality and particle size are determined by the operating conditions in the crystallization process. Thus, in order to obtain desired end-products, the crystallization process should be effectively controlled based on reliable kinetic information, which can be provided by powerful analytical tools such as Raman spectrometry and thermal analysis. The present research work studied various crystallization processes such as reactive crystallization, precipitation with anti-solvent and evaporation crystallization. The goal of the work was to understand more comprehensively the fundamentals, phenomena and utilizations of crystallization, and establish proper methods to control particle size distribution, especially for three phase gas-liquid-solid crystallization systems. As a part of the solid-liquid equilibrium studies in this work, prediction of KCl solubility in a MgCl2-KCl-H2O system was studied theoretically. Additionally, a solubility prediction model by Pitzer thermodynamic model was investigated based on solubility measurements of potassium dihydrogen phosphate with the presence of non-electronic organic substances in aqueous solutions. The prediction model helps to extend literature data and offers an easy and economical way to choose solvent for anti-solvent precipitation. Using experimental and modern analytical methods, precipitation kinetics and mass transfer in reactive crystallization of magnesium carbonate hydrates with magnesium hydroxide slurry and CO2 gas were systematically investigated. The obtained results gave deeper insight into gas-liquid-solid interactions and the mechanisms of this heterogeneous crystallization process. The research approach developed can provide theoretical guidance and act as a useful reference to promote development of gas-liquid reactive crystallization. Gas-liquid mass transfer of absorption in the presence of solid particles in a stirred tank was investigated in order to gain understanding of how different-sized particles interact with gas bubbles. Based on obtained volumetric mass transfer coefficient values, it was found that the influence of the presence of small particles on gas-liquid mass transfer cannot be ignored since there are interactions between bubbles and particles. Raman spectrometry was successfully applied for liquid and solids analysis in semi-batch anti-solvent precipitation and evaporation crystallization. Real-time information such as supersaturation, formation of precipitates and identification of crystal polymorphs could be obtained by Raman spectrometry. The solubility prediction models, monitoring methods for precipitation and empirical model for absorption developed in this study together with the methodologies used gives valuable information for aspects of industrial crystallization. Furthermore, Raman analysis was seen to be a potential controlling method for various crystallization processes.

How Lean Six Sigma and Agile principles optimize ITIL-based processes

Imagine the potential implications of an organization whose business and IT processes are well aligned and are capable of reactively and proactively responding to the external and internal changes. The Philips IT Infrastructure and Operations department (I&O) is undergoing a series of transformation activities to help Philips business keeping up with the changes. I&O would serve a critical function in any business sectors; given that the I&O’s strategy switched from “design, build and run” to “specify, acquire and performance manage”, that function is amplified. In 2013, I&O’s biggest transforming programme I&O Futures engaged multiple interdisciplinary departments and programs on decommissioning legacy processes and restructuring new processes with respect to the Information Technology Internet Library (ITIL), helping I&O to achieve a common infrastructure and operating platform (CI&OP). The author joined I&O Futures in the early 2014 and contributed to the CI&OP release 1, during which a designed model Bing Box and its evaluations were conducted through the lens of six sigma’s structured define-measure-analyze-improve-control (DMAIC) improvement approach. This Bing Box model was intended to firstly combine business and IT principles, namely Lean IT, Agile, ITIL best practices, and Aspect-oriented programming (AOP) into a framework. Secondly, the author implemented the modularized optimization cycles according to the defined framework into Philips’ ITIL-based processes and, subsequently, to enhance business process performance as well as to increase efficiency of the optimization cycles. The unique of this thesis is that the Bing Box model not only provided comprehensive optimization approaches and principles for business process performance, but also integrated and standardized optimization modules for the optimization process itself. The research followed a design research guideline that seek to extend the boundaries of human and organizational capabilities by creating new and innovative artifacts. The Chapter 2 firstly reviewed the current research on Lean Six Sigma, Agile, AOP and ITIL, aiming at identifying the broad conceptual bases for this study. In Chapter 3, we included the process of constructing the Bing Box model. The Chapter 4 described the adoption of Bing Box model: two-implementation case validated by stakeholders through observations and interviews. Chapter 5 contained the concluding remarks, the limitation of this research work and the future research areas. Chapter 6 provided the references used in this thesis.

吳醫彚講Wu yi hui jiang.Collection de traités des médecins de Wu.

Contient : I, livre 1禱告藥王誓疏Dao gao yue wang shi su.Prière au dieu de la médecine ; II, livre 1溫證論治Wen zheng lun zhi.Du traitement en cas de diagnostic par le tiède ; III, livre 1人身一小天地論Ren shen yi xiao tian di lun.Traité des analogies entre le corps humain (microcosme) et l'univers ; IV, livre 1書方宜人共識說Shu fang yi ren gong shi shuo.Traité sur l'exécution des ordonnances ; V, livre 2日講雜記Ri jiang za ji.Notes sur des leçons quotidiennes ; VI, livre 2金匱上工治未病一節辯Jin gui shang gong zhi wei bing yi jie bian.Discussion d'un point du Jin gui yao lüe lun ; VII, livre 3石芝醫話Shi zhi yi hua.Notes médicales de Shi zhi ; VIII, livre 3管見芻言Guan jian chu yan.Vues étroites et paroles humbles ; IX, livre 3核骨踝脛腨辨He gu hua xing shan bian.Discussion relative à la cheville, au tibia, au mollet ; X, livre 3爛喉丹痧論Lan hou dan sha (?) lun.Traité des inflammations et ulcérations de la gorge.Zang fu shou sheng bian.Discussion du contenu des organes internes.Bian zi rong zhi wei.Pour distinguer le faux zi rong, etc ; XI, livre 3大豆黃卷辯Da dou huang juan bian.Discussion au sujet du médicament da dou huang juan.Wen yi zhui yan.Notes sur les maladies épidémiques ; XII, livre 3合論丹溪景岳相火大意He lun dan qi jing yue xiang he da yi.Sur le sens de l'expression xiang he, d'après Dan qi et Jing yue ; XIII, livre 4人身一小天地亦有南北兩極論Ren shen yi xiao tian di yi you nan bei liang ji lun.Le corps humain, étant un microcosme, a un pôle nord et un pôle sud.Ming men mo zhen bian.De l'examen de la veine du rein droit ; XIV, livre 4治肝補脾論Zhi gan bu pi lun.Traitement du foie et de la rate ; XV, livre 4四維相代陽氣乃竭解Si wei xiang dai yang qi nai jie jie.Explication de la phrase : par la succession des quatre wei, le souffle mâle s'épuise ; XVI, livre 4辯素問濁氣歸心之訛Bian su wen zhuo qi gui xin zhi wo.Discussion de l'assertion erronée du Su wen que le souffle trouble revient au cœur ; XVII, livre 4祖氣論Zu qi lun.Sur l'influence productrice du ciel et de la terre ; XVIII, livre 5痘毒藏脾經說Dou du cang pi jing shuo.Le virus de la petite vérole est contenu dans la rate.Dou chu tong shi lun.Sur l'apparition simultanée de la petite vérole.Dou you tai yin zhuan shu yang ming lun.La petite vérole, du principe femelle, évolue vers le principe mâle ; XIX, livre 5擬張令韶傷寒直解辨證歌Yi zhang ling shao shang han zhi jie bian zheng ge.Sur le diagnostic de la fièvre typhoïde ; XX, livre 6三皇藥王考San huang yue wang kao.Sur la divinité de la médecine ; XXI, livre 6脈訣正訛Mo jue zheng wo.Correction au Mo jue ; XXII, livre 6趨庭雜記Qu ting za ji.Notes d'après Qu ting ; XXIII, livre 6辨醫書音義Bian yi shu yin yi.Discussion sur le son et le sens de termes employés dans les livres de médecine.Xia yue ji zhi shuo.Traité sur l'oranger épineux qui doit être évité pendant l'été ; XXIV, livre 6喜傷心恐勝喜解Xi shang xin kong sheng xi jie.Traité sur les maladies provenant de l'excès ou du défaut du souffle vital ; XXV, livre 6百合病贅言Bai he bing zhui yan.Notes sur la maladie appelée bai he ; XXVI, livre 7辨脾胃升降Bian pi wei sheng jiang.Discussion sur un traitement de la rate et de l'estomac ; XXVII, livre 7氣有餘便是火解Qi you yu bian shi he jie.Explication de la phrase : s'il y a excès d'esprit, c'est l'influence du feu.Dong yuan jing yue lun xiang he bian.Discussion des opinions de Zhang Jing yue et de Li Gao sur l'examen du principe feu ; XXVIII, livre 7幼科似驚非驚辨You ke si jing fei jing bian.Discussion sur une affection qui ressemble à la maladie dite jing (trouble, effroi) ; XXIX, livre 7司馬運氣贅言Si tian yun qi zhui yan.Notes sur les influences exercées par les principes célestes.Zhou shen jing luo zong jue.Traité du système des vaisseaux ; XXX, livre 8木鬱達之論Mu yu da zhi lun.Traité relatif à une phrase du Nei jing ; XXXI, livre 8保護元陽說Bao hu yuan yang shuo.Traité sur la protection du principe mâle ; XXXII, livre 8讀傷寒論附記Du shang han lun fu ji.Notes à propos du traité de la fièvre typhoïde ; XXXIII, livre 8論白痘Lun bai phei.Dissertation sur la maladie appelée pei blanche (ulcères laissant des croûtes ou cicatrices blanches) ; XXXIV, livre 8爛喉痧論Lan hou sha (?) lun.Traité des inflammations et ulcérations de la gorge ; XXXV, livre 8爛喉丹痧治宜論Lan hou dan sha (?) zhi yi lun.Sur le traitement des inflammations et ulcérations de la gorge ; XXXVI, livre 8痧疹今昔不同治法亦異說Sha (?) zhen jin xi bu tong zhi fa yi yi shuo.La maladie appelée sha (?) n'étant pas la même aujourd'hui qu'autrefois, le traitement aussi doit différer ; XXXVII, livre 8攝生雜話Sha sheng za hua.Notes pour régler la vie ; XXXVIII, livre 9四大家辯Si da jia bian.Discussion à propos de quatre personnages célèbres ; XXXIX, livre 9攷正古方權量說Kao zheng gu fang quan liang shuo.Traité sur la correction des poids des anciennes formules ; XL, livre 9生氣通天論病因章句辯Sheng qi tong tian lun bing yin zhang ju bian.Discussion de quatre paragraphes de l'ouvrage de Dan qi intitulé : Ge zhi yu lun ; XLI, livre 10虛勞論Xu lao lun.Traité de la maladie appelée xu lao (consomption ?) ; XLII, livre 10讀先祖保陰煎謹記Du xian zu bao yin jian jin ji.Notes sur la formule Bao yin jian, composée par son aïeul ; XLIII, livre 10六味地黃丸方解Liu wei di huang huan fang jie.Explication de la formule des pilules dites à six ingrédients et à base jaune ; XLIV, livre 10司天運氣徵驗Si tian yun qi zheng yan.Preuves des influences exercées par les principes célestes ; XLV, livre 11三焦說San jiao shuo.Traité des trois jiao

全人矩矱Quan ren ju he.La règle de tout l'homme.

Contient : I, livre préliminaire太上感應篇纂註Tai shang gan ying pian zuan zhu.Le Tai shang gan ying pian, avec commentaires ; II, livre préliminaire文昌帝君陰隲文纂註Wen chang di jun yin zhi wen zuan zhu.Le Yin zhi wen, du dieu de la Littérature, avec commentaires ; III, livre préliminaire文昌帝君覺世文纂註Wen chang di jun jue shi wen zuan zhu.Traité pour éveiller le monde, par le dieu de la Littérature ; IV, livre préliminaire關聖帝君覺世經 。釋略并諭Guan sheng di jun jue shi jing. Shi lüe bing yu.Le vrai livre sacré du réveil du monde, par le dieu de la Guerre ; V, livre préliminaire純陽祖師警士文Chun yang zu shi jing shi wen.Avertissement aux lettrés, traité du dieu Fu you ; VI, livre préliminaire魏元君勸世文Wei yuan jun quan shi wen ; VII, livre 1勸孝集說Quan xiao ji shuo.Recueil de textes recommandant la piété filiale ; VIII, livre 2戒淫集說Jie yin ji shuo.Recueil de textes contre l'impureté ; IX, livre 2文昌帝君戒淫文Wen chang di jun jie yin wen.Traité contre l'impureté, par le dieu de la Littérature ; X, livre 2文昌帝君天戒錄Wen chang di jun tian jie lu.Défenses célestes, notées par le dieu de la Littérature ; XI, livre 2三丰張眞人戒淫說San feng zhang zhen ren jie yin shuo.Traité contre l'impureté, par l'homme vrai Zhang, de San feng ; XII Livre 2文昌帝君慾海廻狂寶訓Wen chang di jun yu hai hui kuang bao xun.Instructions pour tirer l'insensé de la mer de la concupiscence, par le dieu de la Littérature ; XIII, livre 3勸戒彚抄Quan jie hui chao.Recueil de conseils et de défenses.Wen di quan zhong.Traité pour conseiller la fidélité, par le dieu de la Littérature ; XIV, livre 3文帝戒士子文Wen di jie shi zi wen.Conseils aux lettrés, par le dieu de la Littérature ; XV, livre 3文帝鱣壇勸世文Wen di zhan tan quan shi wen.Conseils donnés au monde par le dieu de la Littérature, à l'autel Zhan ; XVI, livre 3文帝鱣壇語錄Wen di zhan tan yu lu.Entretiens du dieu de la Littérature à l'autel Zhan ; XVII, livre 3蕉窻十則并序Jiao chuang shi ze bing xu.Les dix commandements de Jiao tchhoang, avec préface ; XVIII, livre 3文帝三教論 。七願 。十戒Wen di san jiao lun. Qi yuan. Shi jie.Dissertation sur les trois religions ; les sept vœux ; les dix commandements : du dieu de la Littérature ; XIX, livre 3呂祖師訓世文Lü zu shi xun shi wen.Instructions au monde par le dieu Fu you ; XX, livre 3勸敬惜字紙文Quan jing xi zi zhi wen.Traité pour conseiller le respect des caractères d'écriture ; XXI, livre 3敬字說Jing zi shuo.Traité sur le respect des caractères d'écriture ; XXII, livre 3惜字說Xi zi shuo.Traité sur le ménagement des caractères d'écriture ; XXIII, livre 3勸敬惜五榖文Quan jing xi Wu gu wen.Traité du respect des cinq sortes de grains ; XXIV, livre 3戒殺生說Jie sha sheng shuo.Traité pour défendre de tuer les êtres ayant vie ; XXV, livre 3戒溺女說Jie ni nü shuo.Traité pour défendre de noyer les petites filles ; XXVI, livre 3戒賭文Jie du wen.Traité contre le jeu ; XXVII, livre 3戒嗜酒Jie shi jiu.Défense d'aimer le vin ; XXVIII, livre 3戒貪財Jie tan cai.Défense de convoiter les richesses ; XXIX, livre 3戒聽讒Jie ting chan.Défense d'écouter la calomnie ; XXX, livre 3戒口過文Jie kou ge wen.Traité pour interdire les péchés de langue ; XXXI, livre 3戒損人利己說Jie sun ren li ji shuo.Traité pour interdire de chercher des avantages personnels au détriment d'autrui ; XXXII, livre3不自棄文Bu zi qi wen.Traité recommandant de ne pas s'abandonner au vice ; XXXIII, livre 3戒慢葬Jie man zang.Traité pour défendre d'user de négligence dans les funérailles ; XXXIV, livre 3戒不修治墳墓Jie bu xiu zhi fen mu.Traité recommandant d'entretenir les tombes ; XXXV, livre 3勸塾師培植子弟Quan shu shi pei zhi zi di.Traité recommandant aux maîtres de prendre soin de leurs élèves ; XXXVI, livre 3勸尊重師傅Quan zun zhong shi fu.Traité recommandant aux élèves d'honorer leur maître ; XXXVII, livre 3勸幕賓Quan mo bin.Conseils aux secrétaires privés des mandarins ; XXXVIII, livre 3勸公門修行Quan gong men xiu xing.Dans les affaires publiques, il faut régler sa conduite ; XXXIX, livre 3勸擇術慎業Quan ze shu shen ye.Il faut choisir un métier et s'y appliquer ; XL, livre 3勸化惡助善Quan hua e zu shan.Il faut corriger le mal et contribuer au bien ; XLI, livre 3勸排難解紛Quan phai nan jie fen.Il faut écarter les obstacles et dissiper les difficultés ; XLII, livre 3勸謙和雍睦Quan qian he yong mu.Traité pour conseiller l'esprit de conciliation et de concorde ; XLIII, livre 3勸救濟Quan jiu ji.Il faut aider (ceux qui ont besoin d'aide) ; XLIV, livre 3賑饑十二善Zhen ji shi er shan.Il faut nourrir les affamés ; XLV, livre 3勸敬說Quan jing shuo.Traité sur le respect ; XLVI, livre 3勸畏說Quan wei shuo.Traité sur la crainte respectueuse ; XLVII, livre3改過之法Gai ge zhi fa.Moyen de corriger les fautes ; XLVIII, livre3勸惜福Quan xi fu.Il faut ménager sa part de bonheur ; XLIX, livre3耕心說Geng xin shuo. Autre titre : 勸耕治心地Quan geng zhi xin di.Il faut cultiver son cœur ; L, livre3廣立命說Guang li ming shuo.Développement du traité sur la direction de la vie ; LI, livre3為學當從事性道Wei xue lang cong shi xing dao.Pour étudier, il faut s'appliquer à la voie naturelle ; LII, livre3性道集說Xing dao ji shuo.Recueil de textes sur la voie naturelle ; LIII, livre3夢覺圖說Mong jue tu shuo.Traité et figure sur l'illusion universelle ; LIV, livre4功過格彚編Gong ge ge hui bian.Liste des mérites et des péchés ; LV, livre4行功過格說Xing gong ge ge shuo.Traité sur l'usage de l'échelle des mérites et des péchés ; LVI, livre4功過格例Gong ge ge li.Règles annexes à l'échelle des mérites et des péchés ; LVII, livre4功過格分類彚編Gong ge ge fen lei hui bian.Liste méthodique des mérites et des péchés ; LVIII, livre 4不費錢功德例Bu fei qian gong de li.Manière d'obtenir des mérites sans dépenser d'argent ; LIX, livre final勸世詩歌Quan shi shi ge.Recueil de poésies morales