The creep of zirconium in water from 400° to 600°F /

"Contract AT-30-1-Gen-366."

Unit course of study in nutrition for one year for rural schools. Grades I through VIII.

Mimeographed.

The Royal institute of painters in water colours,

"A chronological list of the members and associates of the Royal institute of painters in water colours from the foundation of the society in 1831 to the present time": p. vii-xi.

Algae in water supplies; an illustrated manual on the identification, significance, and control of algae in water supplies.

Mode of access: Internet.

Exhibition of drawings in water colour by Alfred William Hunt ...

Biographical sketch of Hunt by Cosmo Monkhouse.

Experimental and theoretical investigation of cavitation in water /

Mode of access: Internet.

Advisory report on health effects of barium in water : ... prepared for the Illinois Institute for Environmental Quality /

Includes bibliographical references.

The camera; or, Art of drawing in water colours : with instructions for sketching form nature : comprising the whole process of water-coloured drawing, familiarly exmplified in drawing, shadowing, and tinting a complete landscape ... and directions for compounding and using colours, sepia, Indian ink, bister, &c.

Mode of access: Internet.

Polyperiod analysis of growth and capital accumulation of farms in the rolling plains of Oklahoma and Texas /

Selected references: p. 87-88.

History of Charlestown in New Hampshire : from its first grant by the province of Massachusetts in 1735, to the year 1833 /

Mode of access: Internet.

Method of analysis and quality-assurance practices for determination of pesticides in water by solid-phase extraction and capillary-column gas chromatography/mass spectrometry at the U.S. Geological Survey California District Organic Chemistry Laboratory, 1996-99 /

Mode of access: Internet.

Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo.

We show that the mutant Huntington's disease (HD) protein (mhtt) specifically inhibits endocytosis in primary striatal neurons. Unexpectedly, mhtt does not inhibit clathrin-dependent endocytosis as was anticipated based on known interacting partners. Instead, inhibition occurs through a non-clathrin, caveolar-related pathway. Expression of mhtt inhibited internalization of BODIPY-lactosylceramide (LacCer), which is internalized by a caveolar-related mechanism. In contrast, endocytosis of Alexa Fluor 594-transferrin (Tfn) and epidermal growth factor, internalized through clathrin pathway, was unaffected by mhtt expression. Caveolin-1 (cav1), the major structural protein of caveolae binds cholesterol and is responsible for its trafficking inside cells. Mhtt interacts with cav-1 and caused a striking accumulation of intracellular cholesterol. Cholesterol accumulated in cultured neurons expressing mhtt in vitro and in brains of mhtt-expressing animals in vivo, and was observed after induction of mhtt expression in PC-12 cell lines. The accumulation occurred only when mhtt and cav1 were simultaneously expressed in cells. Knockdown of cav1 in mhtt-expressing neurons blocked cholesterol accumulation and restored LacCer endocytosis. Thus, mhtt and cav1 functionally interact to cause both cellular defects. These data provide the first direct link between mhtt and caveolar-related endocytosis and also suggest a possible mechanism for HD neurotoxicity where cholesterol homeostasis is perturbed.

Factors influencing the seasonal accumulation of solids in bacteria beds treating domestic sewage

DUE TO COPYRIGHT RESTRICTIONS ONLY AVAILABLE FOR CONSULTATION AT ASTON UNIVERSITY LIBRARY AND INFORMATION SERVICES WITH PRIOR ARRANGEMENT

Quantitative Analysis and Determination of Microcystin in water by Capillary Electrophoresis Mass Spectrometry

The presence of harmful algal blooms (HAB) is a growing concern in aquatic environments. Among HAB organisms, cyanobacteria are of special concern because they have been reported worldwide to cause environmental and human health problem through contamination of drinking water. Although several analytical approaches have been applied to monitoring cyanobacteria toxins, conventional methods are costly and time-consuming so that analyses take weeks for field sampling and subsequent lab analysis. Capillary electrophoresis (CE) becomes a particularly suitable analytical separation method that can couple very small samples and rapid separations to a wide range of selective and sensitive detection techniques. This paper demonstrates a method for rapid separation and identification of four microcystin variants commonly found in aquatic environments. CE coupled to UV and electrospray ionization time-of-flight mass spectrometry (ESI-TOF) procedures were developed. All four analytes were separated within 6 minutes. The ESI-TOF experiment provides accurate molecular information, which further identifies analytes.