Carta Circular de la Red de Cooperación en la Gestión Integral de Recursos Hídricos para el Desarrollo Sustentable en América Latina y el Caribe N° 43

Editorial.-- Discusión abierta: Eficiencia energética y regulación económica en los servicios de agua potable ; Políticas e institucionalidad en materia de agua potable y saneamiento en la región.-- Noticias de la RED: Los países del Golfo Arábico y su objetivo de autosuficiencia alimentaria ; Hacia la reducción de las brechas en agua potable y saneamiento en Colombia ; Presupuesto participativo en agua potable: una oportunidad para los usuarios ; Ley de las organizaciones de usuarios de aguas del Perú ; Comisión de gestión integral de la Cuenca del Río Grande de Tárcoles en Costa Rica ; Unidad Gestora de agua y saneamiento en Panamá ; Cursos: Curso "Aspectos estratégicos del riego".-- Noticias sobre internet y WWW

Network for Cooperation in Integrated Water Resource Management for Sustainable Development in Latin America and the Caribbean No. 43

Editorial remarks.-- Open discussion: Energy efficiency and economic regulation in water supply and sewerage services ; Policies and institutional frameworks for drinking water supply and sanitation.-- News of the network: The goal of food self-sufficiency of the countries of the cooperation council for de Arab States of the Gulf ; Narrowing the gaps in drinking water and sanitation: an opportunity for users ; Water Users'Organizations Act of Peru ; Commission for the Integrated management of the Tárcoles River Basin, Costa Rica ; Water and sanitation Management Unit in Panama.-- Courses: Course "Strategic aspects of irrigation".-- Internet and WWW news

Estudo comparativo de isolados de P. brasiliensis em adesão celular. Sinalização celular mediada pela GP 43

Pós-graduação em Biociências e Biotecnologia Aplicadas à Farmácia - FCFAR

Efeito do betacaroteno sobre o estresse oxidativo e a expressão de conexina 43 cardíaca

BACKGROUND: Intervention studies have shown an increased mortality in patients who received beta-carotene. However, the mechanisms involved in this phenomenon are still unknown. OBJECTIVE: Evaluate the influence of beta-carotene on oxidative stress and the expression of connexin 43 in rat hearts. METHODS: Wistar rats, weighing approximately 100 g, were allocated in two groups: Control Group (n=30), that received the diet routinely used in our laboratory, and Beta-Carotene Group (n = 28), which received beta-carotene (in crystal form, added and mixed to the diet) at a dose of 500 mg of beta-carotene/kg of diet. The animals received the treatment until they reached 200-250g, when they were sacrificed. Samples of blood, liver and heart were collected to perform Western blotting and immunohistochemistry for connexin 43; morphometric studies, dosages of beta-carotene by high-performance liquid chromatography as well as reduced glutathione, oxidized glutathione and lipids hydroperoxides were performed by biochemical analysis. RESULTS: Beta-carotene was detected only in the liver of Beta-Carotene Group animals (288 ± 94.7 µg/kg). Levels of reduced/oxidized glutathione were higher in the liver and heart of Beta-Carotene Group animals (liver - Control Group: 42.60 ± 1.62; liver - Beta-Carotene Group: 57.40 ± 5.90; p = 0.04; heart: - Control Group: 117.40 ± 1.01; heart - Beta-Carotene Group: 121.81 ± 1.32 nmol/mg protein; p = 0.03). The content of total connexin 43 was larger in Beta-Carotene Group. CONCLUSION: Beta-carotene demonstrated a positive effect, characterized by the increase of intercellular communication and improvement of anti-oxidizing defense system. In this model, mechanism does not explain the increased mortality rate observed with the beta-carotene supplementation in clinical studies. (Arq Bras Cardiol. 2013; [online].ahead print, PP.0-0)

Unesp Informa, 2013, número 43

Boletim elaborado pela Assessoria de Comunicação e Imprensa da Reitoria da UNESP

Unesp Ciência, 2013, ano 4, número 43

Revista elaborada pela Assessoria de Comunicação e Imprensa da Reitoria da UNESP

South Carolina Farmer's Alliance Papers - Accession 43 - M18 (28)

The South Carolina Farmer's Alliance Papers consist of a reminiscence of the Farmer’s Alliance by W.A. James of Bishopville, SC, who was a county business agent for Sumter County. Also included is a two page comment by Dr. John H. Moore of the Winthrop History Department. The Farmers Alliance was an organized agrarian economic movement among farmers that developed and flourished from the 1870s through 1900.

JAVMA37-43 Anthrax in Swine

Anthrax is not commonly considered so important a menace to swine as it is to other forms of live stock, in which the disease is apt to declare itself with terrifying severity. In comparison with the marked mortality frequently observed in cattle, the tangible losses caused by anthrax in swine seem negligible. As recent as 25 years ago, there still were observers who sincerely doubted the occurrence of the disease in hogs and this opinion found some support in the many reported failures to induce the infection in that animal species by artificial methods.

RP97-43 Tax Planning When Buying or Selling a Farm

If you're like most farmers, one of your key goals is to maximize after-tax earnings. The more money left over after you've paid your farm bills land your taxes, the more you and your family will have to spend. You can increase thos enet earnings in sveral ways: by increasing production, by decreasing cost of supplies oer by finding a way to get more for your produce. But there's another way to increase your after-tax earnings. One that many farmers oculd afford to spen dmore time on: decreasing taxes. The key to avoiding unnecessary taxes is tax planning. This publication will help you do just that: plan for the future.

Prophylactic and Therapeutic Vaccination Using Dendritic Cells Primed with Peptide 10 Derived from the 43-Kilodalton Glycoprotein of Paracoccidioides brasiliensis

Vaccination with peptide 10 (P10), derived from the Paracoccidioides brasiliensis glycoprotein 43 (gp43), induces a Th1 response that protects mice in an intratracheal P. brasiliensis infection model. Combining P10 with complete Freund's adjuvant (CFA) or other adjuvants further increases the peptide's antifungal effect. Since dendritic cells (DCs) are up to 1,000-fold more efficient at activating T cells than CFA, we examined the impact of P10-primed bone-marrow-derived DC vaccination in mice. Splenocytes from mice immunized with P10 were stimulated in vitro with P10 or P10-primed DCs. T cell proliferation was significantly increased in the presence of P10-primed DCs compared to the peptide. The protective efficacy of P10-primed DCs was studied in an intratracheal P. brasiliensis model in BALB/c mice. Administration of P10-primed DCs prior to (via subcutaneous vaccination) or weeks after (via either subcutaneous or intravenous injection) P. brasiliensis infection decreased pulmonary damage and significantly reduced fungal burdens. The protective response mediated by the injection of primed DCs was characterized mainly by an increased production of gamma interferon (IFN-gamma) and interleukin 12 (IL-12) and a reduction in IL-10 and IL-4 compared to those of infected mice that received saline or unprimed DCs. Hence, our data demonstrate the potential of P10-primed DCs as a vaccine capable of both the rapid protection against the development of serious paracoccidioidomycosis or the treatment of established P. brasiliensis disease.