Utformning av tak och möjligheter med automation av takstolstillverkning i trä

Purpose: The purpose of this work is to increase the possibilities of designing building components for specific demands to increase the building’s value, and to investigate how the possibilities can be affected by automating the production process. Method: The theoretical framework, which this study is based on, was collected using literature studies and was thereafter combined with the empirics, which were retrieved from qualitative methods as interviews and planned observations. A case study was made of the building Ormhuset in Jönköping. Findings: The objective of this work is to investigate the possibilities for designing roofs by using new automation methods for the production process of wooden roof structures. This study implies that parametric design can be used to generate new innovative shapes and designs that are optimised according to specific criteria. Furthermore, an increased use of automation in the production process of wooden roof trusses result in cheaper roof trusses, regardless of their shapes. The generated optimized designs are therefore cheaper and easier to produce using more automation in the production process. Implications: If parametric design is used, almost any kind of shapes can be generated and optimised. To ensure manufacturability of a design, an early connection between architect and manufacturer is important. Furthermore, increased use of automation can lead to easier and faster production of roof trusses and investing in more automation can be relevant for companies with large production volumes. Using digital files to control the manufacturing machines is time saving. There are alternative manufacturing methods for advanced roof structurers in wood, which are better suited for production, which cannot be rationalized as for roof trusses. Constraints for increased automation are often a high investment cost and limited space. Limitations: If the study is performed on another case than Ormhuset and with other respondents, the result might have differed but could be similar, why this study is not generally valid but only shows one possible outcome.

Förändringar i informationshanteringen med användandet av molntjänster : Förändringsanalys hos ett företag inom retailbranschen

Den här studien, som har bedrivits i samarbete med konsultföretaget Pipe, har studerat informationshanteringsprocessen hos småföretag inom retailbranschen. Företaget som ägnar sig åt butiksplanering med hjälp av CAD-program har idag ingen koppling mellan CAD-programmet och den molndatabas som lagrar information. Syftet med arbetet är att beskriva hur ett åtgärdsförslag skulle kunna se ut för att företaget ska kunna förbättra sin informationshantering genom användandet utav en molndatabas. Vi har även beskrivit problemområdet kring kopplingar mellanmolndatabaser och designprogram. För att besvara studiens syfte har vi genomfört en fallstudie, och svaret på forskningsfrågorna, 1. Hur ser informationshanteringsprocessen ut idag? 2. Hur kan informationshanteringsprocessen förbättras? 2. Vilka arbetssteg skulle kunna tas bort om företaget inför en koppling mellanmolndatabasen och designprogrammet? 3. Är en molnbaserad lösning ett möjligt alternativ för att använda för småföretag i retailbranschen? 4. Hur ser det ut i andra branscher som använder sig av CAD-program? Har vi hittat genom att genomföra intervjuer. Intervjuerna har hjälpt oss att genomföra en förändringsanalys där vi genom handlingsgrafer och mål- och problemlistor har kommit fram till ett antal åtgärdsförslag som företaget bör genomföra för att förbättra sin informationshanteringsprocess. Utifrån förändringsanalysen har vi kunnat dra slutsatsen att informationshanteringsprocessen skulle kunna förbättras och snabbas upp genom att införa en koppling mellan designprogrammet och en molndatabas. Detta skulle innebära att material automatiskt laddas upp från designprogrammet tillmolndatabasen, som även kunden har tillgång till. På så sätt samlas all information på ett och samma ställe. Genom litteraturstudier har vi också kommit fram till att en molnbaserad lösning vore möjligt för företaget, då det är en billig och smidig lösning för företag som inte har så stora resurser.

Adenine as an organocatalyst for the ring-opening polymerization of lactide: scope, mechanism and access to adenine-functionalized polylactide

Nucleobase-functionalized polymers are widely used in the fields of supramolecular chemistry and self-assembly, and their development for biomedical applications is also an area of interest. They are usually synthesized by tedious multistep procedures. In this study, we assess adenine as an organoinitiator/ organocatalyst for the ring-opening polymerization of lactide. L-Lactide can be quantitatively polymerized in the presence of adenine. Reaction conditions involving short reaction times and relatively low temperatures enable the access to adenine end-capped polylactide in a simple one-step procedure, in bulk, without additional catalyst. DFT calculations show that the polymerization occurs via hydrogen bond catalysis. The mechanism involves (i) a hydrogen bond between the NH9 of adenine and the carbonyl moiety of lactide, leading to an electron deficient carbon atom, and (ii) a second hydrogen bond between the N3 of adenine and the NH2 of a second adenine molecule, followed by a nucleophilic attack of the latter activated amine on the former electron deficient carbon on the monomer. For longer reaction times and higher temperatures, macrocyclic species are formed, and a mechanism involving the imidazole ring of adenine is proposed based on literature studies. Depending on the reaction conditions, adenine can thus be considered as an organoinitiator or an organocatalyst for the ring-opening polymerization of lactide.

Adenine as an organocatalyst for the ring-opening polymerization of lactide: scope, mechanism and access to adenine-functionalized polylactide

Nucleobase-functionalized polymers are widely used in the fields of supramolecular chemistry and self-assembly, and their development for biomedical applications is also an area of interest. They are usually synthesized by tedious multistep procedures. In this study, we assess adenine as an organoinitiator/organocatalyst for the ring-opening polymerization of lactide. L-Lactide can be quantitatively polymerized in the presence of adenine. Reaction conditions involving short reaction times and relatively low temperatures enable the access to adenine end-capped polylactide in a simple one-step procedure, in bulk, without additional catalyst. DFT calculations show that the polymerization occurs via hydrogen bond catalysis. The mechanism involves (i) a hydrogen bond between the NH9 of adenine and the carbonyl moiety of lactide, leading to an electron deficient carbon atom, and (ii) a second hydrogen bond between the N3 of adenine and the NH2 of a second adenine molecule, followed by a nucleophilic attack of the latter activated amine on the former electron deficient carbon on the monomer. For longer reaction times and higher temperatures, macrocyclic species are formed, and a mechanism involving the imidazole ring of adenine is proposed based on literature studies. Depending on the reaction conditions, adenine can thus be considered as an organoinitiator or an organocatalyst for the ring-opening polymerization of lactide.

Sample size in studies on diagnostic accuracy in ophthalmology:A literature survey

Aim: To assess the sample sizes used in studies on diagnostic accuracy in ophthalmology. Design and sources: A survey literature published in 2005. Methods: The frequency of reporting calculations of sample sizes and the samples' sizes were extracted from the published literature. A manual search of five leading clinical journals in ophthalmology with the highest impact (Investigative Ophthalmology and Visual Science, Ophthalmology, Archives of Ophthalmology, American Journal of Ophthalmology and British Journal of Ophthalmology) was conducted by two independent investigators. Results: A total of 1698 articles were identified, of which 40 studies were on diagnostic accuracy. One study reported that sample size was calculated before initiating the study. Another study reported consideration of sample size without calculation. The mean (SD) sample size of all diagnostic studies was 172.6 (218.9). The median prevalence of the target condition was 50.5%. Conclusion: Only a few studies consider sample size in their methods. Inadequate sample sizes in diagnostic accuracy studies may result in misleading estimates of test accuracy. An improvement over the current standards on the design and reporting of diagnostic studies is warranted.

Compte rendu: Jannis Androutsopoulos (dir.) (2014), Mediatization and sociolinguistic change, Berlin/Boston, De Gruyter, coll. « Linguae & litterae. Publications of the School of Language & Literature Freiburg Institute for Advanced Studies, 36 », vii-557 p. [ISBN : 978-3-11-034357-1]

Résumé non disponible

Foundation studies in literature

UANL

Language, literature and culture in English studies.

El libro analiza la situación de la enseñanza del inglés en educación secundaria, bachillerato, formación profesional y enseñanza de idiomas. Trata las variedades del inglés más importantes, así como los aspectos básicos de la cultura y la historia de los países en que se habla como primera lengua, cuestiones de metodología y evaluación a distintos niveles, de acuerdo con el Marco Común Europeo de Referencia para las Lenguas, y el European Language Portfolio. Completa cada tema con un glosario y una relación de propuestas educacionales y cuestiones abiertas.

Sample sizes of studies on diagnostic accuracy: literature survey

OBJECTIVES: To determine sample sizes in studies on diagnostic accuracy and the proportion of studies that report calculations of sample size. DESIGN: Literature survey. DATA SOURCES: All issues of eight leading journals published in 2002. METHODS: Sample sizes, number of subgroup analyses, and how often studies reported calculations of sample size were extracted. RESULTS: 43 of 8999 articles were non-screening studies on diagnostic accuracy. The median sample size was 118 (interquartile range 71-350) and the median prevalence of the target condition was 43% (27-61%). The median number of patients with the target condition--needed to calculate a test's sensitivity--was 49 (28-91). The median number of patients without the target condition--needed to determine a test's specificity--was 76 (27-209). Two of the 43 studies (5%) reported a priori calculations of sample size. Twenty articles (47%) reported results for patient subgroups. The number of subgroups ranged from two to 19 (median four). No studies reported that sample size was calculated on the basis of preplanned analyses of subgroups. CONCLUSION: Few studies on diagnostic accuracy report considerations of sample size. The number of participants in most studies on diagnostic accuracy is probably too small to analyse variability of measures of accuracy across patient subgroups.