L'Univers

1870/04/17 (Numéro 1077).

Neuroethologic differences in sleep deprivation induced by the single- and multiple-platform methods

It has been proposed that the multiple-platform method (MP) for desynchronized sleep (DS) deprivation eliminates the stress induced by social isolation and by the restriction of locomotion in the single-platform (SP) method. MP, however, induces a higher increase in plasma corticosterone and ACTH levels than SP. Since deprivation is of heuristic value to identify the functional role of this state of sleep, the objective of the present study was to determine the behavioral differences exhibited by rats during sleep deprivation induced by these two methods. All behavioral patterns exhibited by a group of 7 albino male Wistar rats submitted to 4 days of sleep deprivation by the MP method (15 platforms, spaced 150 mm apart) and by 7 other rats submitted to sleep deprivation by the SP method were recorded in order to elaborate an ethogram. The behavioral patterns were quantitated in 10 replications by naive observers using other groups of 7 rats each submitted to the same deprivation schedule. Each quantification session lasted 35 min and the behavioral patterns presented by each rat over a period of 5 min were counted. The results obtained were: a) rats submitted to the MP method changed platforms at a mean rate of 2.62 ± 1.17 platforms h-1 animal-1; b) the number of episodes of noninteractive waking patterns for the MP animals was significantly higher than that for SP animals (1077 vs 768); c) additional episodes of waking patterns (26.9 ± 18.9 episodes/session) were promoted by social interaction in MP animals; d) the cumulative number of sleep episodes observed in the MP test (311) was significantly lower (chi-square test, 1 d.f., P<0.05) than that observed in the SP test (534); e) rats submitted to the MP test did not show the well-known increase in ambulatory activity observed after the end of the SP test; f) comparison of 6 MP and 6 SP rats showed a significantly shorter latency to the onset of DS in MP rats (7.8 ± 4.3 and 29.0 ± 25.0 min, respectively; Student t-test, P<0.05). We conclude that the social interaction occurring in the MP test generates additional stress since it increases the time of forced wakefulness and reduces the time of rest promoted by synchronized sleep.

Le Petit journal. Supplément du dimanche

1911/07/09 (Numéro 1077).

L'Écho de Paris

1887/02/25 (Numéro 1077).

Mélanges historiques sur la Champagne, l'Artois et la Picardie.

Contient : Extraits d'un livre de réception des chanoines de l'église de Troyes ; Ligues des nobles de Champagne, Vermandois, Beauvaisis, etc ; Extraits de l'obituaire de Saint-Étienne de Troyes ; Extraits des chartes de Montier-la-Celle ; Accord entre Blanche, comtesse de Champagne, et Érard de Brienne ; Pièces relatives à l'abbaye de Signy ; Accord entre Jean de Châtillon, comte de Porcien, et l'abbaye de Saint-Hubert en Ardennes ; Chartes des seigneurs de Bazoches ; Extraits du cartulaire de l'abbaye du Charme-aux-Nonnains ; Charte de Gisla pour Sainte-Gertrude de Nivelles ; Extrait du martyrologe de l'église de Laon ; Bulles et chartes relatives à la même église ; Notice sur Gaudri, évêque de Laon ; Chartes de Saint-Jean de Laon ; Chartes concernant le diocèse de Laon ; Fondation de la chapelle de La Neuville-en-Hez ; Notice d'une donation faite par Guillaume le Conquérant à Saint-Étienne de Caen ; Diplôme de Robert le Pieux pour Saint-Vaast, daté de 1039 ; Chartes concernant les comtés de Boulogne et de Ponthieu ; Extraits de chartes concernant le diocèse d'Arras ; Extraits concernant les comtes de Saint-Pol ; Extrait des titres de Saint-Vaast d'Arras ; Extraits concernant les comtes de Flandre ; Diplôme d'Eudes pour Saint-Vaast ; Charte du comte Albert pour l'abbaye de Saint-Quentin ; Charte de Baudouin, comte de Flandre, pour Saint-Pierre au Mont-Blandin ; Extraits du cartulaire du Mont-Saint-Martin ; Épitaphes diverses de l'Artois ; Funérailles de Louis de Male, comte de Flandre