987 resultados para Woodruff, Samuel D.


Relevância:

80.00% 80.00%

Publicador:

Resumo:

Using survey data from natural experiments in three countries that simultaneously received food aid sourced locally and from the United States, we test the hypothesis that locally-sourced commodities are more culturally appropriate and thus preferred over traditional food aid commodities sourced from the donor country. We use a semi-nonparametric regression method to estimate recipients' satisfaction with these commodities across a range of criteria. We establish that recipients of locally procured rations are generally more satisfied with the commodities they receive than are recipients of US-sourced foods. This pattern is especially pronounced among less-well-off recipients. (C) 2013 Elsevier Ltd. All rights reserved.

Relevância:

80.00% 80.00%

Publicador:

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Obesity has reached epidemic proportions in the United States, with an estimated 50% of adults meeting the definition of being overweight. As this condition has become more prevalent, bariatric surgery has become an increasingly accepted form of treatment of the severely obese. Patients who have had bariatric surgery are presenting more commonly to Emergency Departments as a result. This article will review the most common bariatric surgery procedures, the complications that can arise post-operatively, and the approach to the assessment and management of the bariatric surgery patient in the Emergency Department.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Oncolytic herpes simplex virus type 1 (HSV-1) vectors are promising therapeutic agents for cancer. Their efficacy depends on the extent of both intratumoral viral replication and induction of a host antitumor immune response. To enhance these properties while employing ample safeguards, two conditionally replicating HSV-1 vectors, termed G47Δ and R47Δ, have been constructed by deleting the α47 gene and the promoter region of US11 from γ34.5-deficient HSV-1 vectors, G207 and R3616, respectively. Because the α47 gene product is responsible for inhibiting the transporter associated with antigen presentation (TAP), its absence led to increased MHC class I expression in infected human cells. Moreover, some G47Δ-infected human melanoma cells exhibited enhanced stimulation of matched antitumor T cell activity. The deletion also places the late US11 gene under control of the immediate-early α47 promoter, which suppresses the reduced growth properties of γ34.5-deficient mutants. G47Δ and R47Δ showed enhanced viral growth in a variety of cell lines, leading to higher virus yields and enhanced cytopathic effect in tumor cells. G47Δ was significantly more efficacious in vivo than its parent G207 at inhibiting tumor growth in both immune-competent and immune-deficient animal models. Yet, when inoculated into the brains of HSV-1-sensitive A/J mice at 2 × 106 plaque forming units, G47Δ was as safe as G207. These results suggest that G47Δ may have enhanced antitumor activity in humans.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Calendar published by the Library of Congress in 1917.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

"v.2 edidit ... S. Clarke, filius."

Relevância:

80.00% 80.00%

Publicador:

Resumo:

The work of a group of English writers each letter being signed by an initial indicating the author, as follows. P.-Philip Yorke; C.-Charles Yorke; R.-G.H. Rooke; G.-John Green; W.-Daniel Wray; H.-Henry Heaton; E.-Wm. Heberden; O.-Henry Coventry; L.-John Lawry; T.-Catherine Talbot; B.-Thomas Birch; S.-Samuel Salter. The work was edited by Thomas Birch, the brothers Yorke having the largest share in the composition of the letters.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Also pub. under title: The famous chronicle historie of King Henrie the Eight.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

80.00% 80.00%

Publicador:

Resumo:

Signatures: A¹² b⁶ B-P¹² (H² missigned O²).