The life and labours of Saint Thomas of Aquin /

Mode of access: Internet.

The life of Saint Patrick, Apostle of Ireland, to which is added Saint Fiech's Irish Hymn; also a copious appendix of the various ecclesiastical institutions, &c. in Ireland,

Includes a hymn on the life, virtues and miracles of St. Patrick, composed by St. Fiech.

The utility of serum CA-125 in predicting extra-uterine disease in apparent early stage endometrial cancer

Objectives: To evaluate the clinical value of pre-operative serum CA125 in predicting the presence of extra-uterine disease in patients with apparent early stage endometrial cancer. Methods: Between October 6, 2005 and June 17, 2010, 760 patients were enrolled in an international, multicentre, prospective randomized trial (LACE) comparing laparotomy with laparoscopy in the management of endometrial cancer apparently confined to the uterus. This study is based on data from 657 patients with endometrial adenocarcinoma who had a pre-operative serum CA125 value, and was undertaken to correlate pre-operative serum CA125 with final stage. Results: Using a pre-operative CA-125 cutpoint of 30U/ml was associated with the smallest misclassification error (14.5%) using a multiple cross-validation method. Median pre-operative serum CA-125 was 14U/ml, and using a cutpoint of 30U/ml, 14.9% of patients had elevated CA-125 levels. Of 98 patients with elevated CA-125 level, 36 (36.7%) had evidence of extra-uterine disease. Of the 116 patients (17.7%) with evidence of extra-uterine disease, 31.0% had elevated CA-125 level. In univariate and multivariate logistic regression analysis, only pre-operative CA-125 level was found to be associated with extra-uterine spread of disease. Utilising a cutpoint of 30U/ml achieved a sensitivity, specificity, positive predictive value and negative predictive value of 31.0%, 88.5%, 36.7% and 85.7% respectively. Overall, 326/657 (49.6%) of patients had full surgical staging involving lymph node dissection. When analysis was limited to patients that had undergone full surgical staging, the outcomes remained essentially unchanged. Conclusions: Elevated CA-125 above 30U/ml in patients with apparent early stage disease is associated with a sensitivity of 31.0% and specificity of 88.5% in detecting extra-uterine disease. Pre-operative identification of this risk factor may assist to triage patients to tertiary centres and comprehensive surgical staging.

50th wedding anniversary party of Paul Goldschmidt and Ilse nee Molling; Laguna Hills, CA.

Left to right: Margot Molling, Ilse Molling, Adolf Molling, Paul Goldschmidt (husband of Ilse Molling)

50th wedding anniversary party of Paul Goldschmidt and Ilse nee Molling; Laguna Hills, CA.

Left to right: Margot Molling, Ilse Molling, Adolf Molling, Paul Goldschmidt (husband of Ilse Molling)

Book review of Atlas of Anatomy by Patrick W. Tank and Thomas R. Gest:Book review of Atlas of Anatomy

Book review of Atlas of Anatomy by Patrick W. Tank and Thomas R. Gest

« Li rommans de Godefroy de Buillon et de Salehadin et de tous lez autres roys qui ont esté outre mer jusques a saint Loys qui darrenierement y fu ».

Début : « Si povés vous savoir les sains leus de la terre... — Fin : «... Adonc estoient l'an de l'incarnation Nostre Seigneur mil CCLXI. Explicit les Feiz d'Outremer. Ce livre ci fu complet d'escripture l'an de l'incarnation Nostre Seigneur mil trois cens et trante et VII, le jeudi devant la feste mon seigneur saint Thomas l'apostre devant Noël. » — Nombreuses miniatures. — Au fol. 1, on lit : « Au duc d'Arschot en 1584 ».

Thomas Wallensis in civitatem Dei.

Jacobins de la rue Saint-Honoré.