Preparation and thermal study of Mg-diclofenac compound in solid state

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Thermal decomposition and stability in a series of heterobimetallic carbonyl compounds of the type [Fe(CO)4(HgX)2] (X=Cl, Br, I)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Synthesis, characterization and thermal studies on solid state 3-methoxybenzoate of lighter trivalent lanthanides

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The Effect of the Aminic Substituent on the Thermal Decomposition of Cyclic Dithiocarbamates

Estudos termogravimétricos e calorimétricos diferenciais para ditiocarbamatos de NH4+, Na+, Zn2+, Cd2+ e Pb2+, derivados de aminas cíclicas contendo nitrogênio como heteroátomos, foram realizados em atmosferas de ar e nitrogênio, para avaliar a influência da tensão angular dos anéis na decomposição térmica destes compostos, em relação à formação de tiocianatos metálicos como via de decomposição. Os intemediários formados foram caracterizados por difração de raios-X, tendo sido encontrados oxissulfatos de Zn2+, Cd2+ e Pb2+, sob atmosfera de ar, o que sugere a decomposição térmica nestas condições como via sintética para estes compostos. Os produtos de decomposição final obtidos foram sulfetos metálicos sob nitrogênio e óxidos dos metais de transição e sulfato de sódio sob ar. Entalpias de fusão são também descritas, com base nos resultados de DSC.

Synthesis and thermal study of the prodrug of oxamniquine

Oxamniquine polymeric prodrug with potential antischistosomal activity was prepared using dextran T-70 as a carrier, which was analysed by (HNMR)-H-1, C-13 NMR and IR spectroscopy. The formation of the oxamniquine salt was confirmed by thermogravimetric analysis (TG) and differential scanning calorimetry (DSC) which showed a different thermal behaviour when compared to the physical mixture.

Thermal and spectroscopy investigation of cyclopalladated compounds of the type [Pd(C(1)3H(1)0N)(mu-X)](2), (X=H3CCOO, NCO, SCN, CN)

The dimeric compound [Pd(bzan)(mu-OOCCH3)](2) (1) (bzan=N-benzylideneaniline) reacts with KX, in methanol/acetone (2:1), affording the analogous dimeric pseudohalogen-bridged species [Pd(bzan)(mu-X)](2) [X=NCO(2), SCN(3), CN(4)]. The compounds were characterized by elemental analysis, infrared spectroscopy, NMR and thermogravimetric analysis. IR data for 2-4 showed bands typical of coordinated pseudohalogen ligands clearly indicating the occurrence of the exchange reaction. Their thermal behaviour was investigated and suggested that their stability is influenced by the bridging ligand. The thermal stability decreased in the order [Pd(bzan)(mu-CN)](2)>[Pd(bzan)(mu-SCN)](2)>[Pd(bzan)(mu-OOCCH3)](2)>[Pd(bzan)(mu-NCO)](2). X-ray results showed the formation of Pddegrees as final decomposition product.

Thermal studies on solid compounds of 4-chlorobenzylidenepyruvate of some alkali earth metals

Solid-state M-4-Cl-BP compounds, where M stands for bivalent Mg, Ca, Sr, Ba and 4-Cl-BP is 4-chlorobenzylidenepyruvate, have been synthesized. Simultaneous thermogravimetry-differential thermal analysis (TG-DTA), differential scanning calorimetry (DSC), infrared spectroscopy, elemental analysis and complexometry were used to characterize and to study the thermal behaviour of these compounds. The results led to informations about the composition, dehydration, thermal stability and thermal decomposition of the isolated complexes.

Synthesis, characterization and thermal studies on solid compounds of 2-chlorobenzylidenepyruvate of heavier trivalent lanthanides and yttrium(III)

Solid-state compounds of general formula LnL(3)center dot nH(2)O, where Ln represents heavier lanthanides and yttrium and L is 2-chlorobenzylidenepyruvate, have been synthesized. Chemical analysis, simultaneous thermogravimetry-differential analysis (TG-DTA), differential scanning calorimetry (DSC), X-ray powder diffractometry, elemental analysis and infrared spectroscopy have been employed to characterize and to study the thermal behaviour of these compounds in dynamic air atmosphere.On heating these compounds decompose in four (Gd, Tb, Ho to Lu, Y) or five (Eu, Dy) steps. They lose the hydration water in the first step and the thermal decomposition of the anhydrous compounds up to 1200 degrees C occurs with the formation of the respective oxide, Tb4O7 and Ln(2)O(3) (Ln=Eu, Gd, Dy to Lu and Y) as final residue. The dehydration enthalpies found for these compounds (Eu, to Lu and Y) were: 65.77, 55.63, 86.89, 121.65, 99.80, 109.59, 131.02, 119.78, 205.46 and 83.11 kJ mol(-1), respectively.

Thermal investigation of solid 2-methoxycinnamylidenepyruvate of some bivalent transition metal ions

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Synthesis, characterization and thermal behavior on solid tartrates of light trivalent lanthanides

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Thermal decomposition and stability in a series of tetrafluorborate copper(I) complexes

Tetrafluorborate copper(I) complexes containing acetonitrile, triphenylphosphine, 1,10-phenanthroline, 2,2′-bipyridine and 2-quinolinethiol have been prepared in order to study their thermal stabilities as a function of the ligands present. The characterization of the above compounds was carried out by elemental analysis and IR spectroscopy. Their thermal behaviour has been investigated and the final products were identified by X-ray powder diagrams. © 1995.

Thermal decomposition of some diuretic agents

Thermogravimetry-derivative thermogravimetry and differential scanning calorimetry were used to study the thermal behaviour of furosemide, hydrochlorothiazide, spironolactone, and amiloride hydrochloride. The results revealed the extents of their thermal stability and also permitted interpretations concerning their thermal decompositions. © 1996 Akadémiai Kiadó.

Thermal decomposition of some analgesic agents

Thermogravimetry, derivative thermogravimetry (TG, DTG) and differential scanning calorimetry (DSC), were used to study the thermal behaviour of mefenamic acid, ibuprofen, acetaminophen, sodium diclofenac, phenylbutazone, dipyrone and salicylamide. The results led to thermal stability data and also to the interpretation concerning the thermal decomposition. © 1996 Akadémial Kiadó.

Synthesis and thermal study of 8-hydroxy-quinoline derivatives of the alkaline Earth metals: I. Strontium complexes

Strontium complexes of 5,7-dibromo-, 5,7-dichloro-, 7-iodo- and 5-chloro-7-iodo-8-hydroxyquinoline were precipitated from an aqueous ammonia and acetone medium. The complexes obtained were Sr[(C9H4ONBr2)2]·2.5H 2O; Sr[(C9H4ONCl2)(OH)]·1.5H2O; Sr[(C9H5ONI)2]·5H2O and Sr[(C9H4ONICl)(OH)]·1.25H2O. The residues of their thermal decomposition were SrBr2; a mixture of SrCl2, SrCO3 and SrO3 SrCO3, and SrCO3, respectively. All were characterized by means of thermogravimetry, differential thermal analysis, complexometry with EDTA, atomic absorption spectroscopy, IR spectroscopy and X-ray diffraction. © 1999 Akadémiai Kiadó.

Solid-state compounds of 4-chlorobenzylidenepyruvate with lanthanides preparation and thermal studies

Solid-state compounds Ln-4Cl-BP, where Ln represents lighter trivalent lanthanides and 4Cl-BP is 4-chlorobenzylidenepyruvate, were prepared. Thermogravimetry, derivative thermogravimetry (TG and DTG), differential scanning calorimetry (DSC) and other methods of analysis were used to characterize and to study the thermal behaviour of these compounds.