Avaliação de riscos ambientais no Aeroporto Internacional de Viracopos, Campinas (SP)

Considering the current context of environmental concern, the main purpose of this research was to develop and apply indicators to evaluate the environmental risk for airports. As a result, 19 indicators related to storage and handling dangerous substances were created. These indicators represent five conditions varying from the worst (level 1) to the ideal condition (level 5). The indicators were applied, as a study of case, at Viracopos International Airport, Campinas (SP). The results showed a medium performance of 2.3, using a scale raging from 1.0 to 5.0, characterized as 'critical'. Then, the indicators were analyzed to determine the major weaknesses related to the environmental management at Viracopos International Airport, as well as to identify good practices and solutions. Among the suggested management strategies, we highlight the suitability of areas for storage of dangerous substances. In general, it can be inferred that the indicators proposed in this paper to evaluate the performance in the management of environmental risks at the Viracopos International Airport and propose actions to prevent, monitor, correct, and mitigate the environmental impacts of its operations.

Indicadores para a gestão de resíduos sólidos em aeroportos e sua aplicação no Aeroporto Internacional de Viracopos, Campinas, São Paulo

Taking into account the current context about environmental concern, the main purposes of this research were to develop and apply indicators in order to evaluate waste residues management in airports. As a result, 17 indicators related to generation, storage, transportation, collection, and solid waste disposal were created. These were applied in Viracopos International Airport, in Campinas, São Paulo State, Brazil. The results obtained in the study had a 2.9 performance, in a scale from one to five, characterized as regular. Posteriorly, the main weaknesses in waste residues management were analyzed in such Airport, as well as good practices and solutions were identifed. The highlighted management strategies suggested were the adjustment of areas for waste storage, recycling, and residues composting.

Acute Phase Responses of Different Positions of High-Goal (Elite) Polo Ponies

The aim of this study was to investigate the acute phase response (APR) in 15 horses by quantifying physiological venous blood variables and serum acute phase proteins (APP) at 5 minutes and 6 and 12 hours after a training match of high-goal polo. The horses were divided into three experimental groups based on their team positions, including defense (n = 6), midfield (n = 5), and attack (n = 4). Serum proteinograms were obtained by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). Data were evaluated using analysis of variance for repeated measures. The match represented a high-intensity stimulus for all positions. Defenders appeared to use the anaerobic pathway more than the other positions, as shown by their lower pH and greater lactatemia. Alterations in muscle membrane permeability were observed in all horses, as seen by the increase in serum creatine kinase activity without a correlation with APR. Significant elevations in total serum protein, albumin, ceruloplasmin, haptoglobin, alpha-1 antitrypsin, and 23-kDa protein were seen only during the course of the physical exertion of the match, although there were no differences in these values among positions of the team. After 6 hours of the match, the concentration of transferrin declined, whereas that of alpha-1 acid glycoprotein remained unaltered at all assessed times. These results demonstrated that the defenders required the most use of the anaerobic pathway during the match, and that equestrian polo exercise triggers an acute phase response of relatively short duration; this APR is characterized as noninflammatory, as APR appears to be a physiological alteration related to the stress inherent in physical exercise. © 2013 Elsevier Inc. All rights reserved.

In vitro targeting of Polo-like kinase 1 in bladder carcinoma: Comparative effects of four potent inhibitors

Despite the improvements in neoadjuvant chemotherapy, the outcome of patients with advanced bladder cancer has changed very little over the past 30 years. In the present study we tested and compared the in vitro antitumor activities of four different inhibitors of Polo-like kinase 1 (PLK1) (BI 2536, BI 6727, GW843682X, and GSK461364), against 3 bladder carcinoma cell lines RT4, 5637 and T24. The impact on radiosensitivity and drug interactions in simultaneous treatments with cisplatin, methotrexate, and doxorubicin were also investigated. Our results showed that PLK1 inhibition prevented cell proliferation and clonogenicity, causing significant inhibition of invasion of tumor cells, though modest differences were observed between drugs. Moreover, all PLK1 inhibitors induced G2/M arrest, with the subsequent induction of death in all 3 cell lines. Drug interactions studies showed auspicious results for all PLK1 inhibitors when combined with the commonly used cisplatin and methotrexate, though combinations with doxorubicin showed mostly antagonistic effects. Comparably, the four PLK1 inhibitors efficiently sensitized cells to ionizing radiation. Our findings demonstrate that irrespective of the inhibitor used, the pharmacological inhibition of PLK1 constrains bladder cancer growth and dissemination, providing new opportunities for future therapeutic intervention. However, further laboratorial and preclinical tests are still needed to corroborate the usefulness of using them in combination with other commonly used chemotherapeutic drugs. © 2013 Landes Bioscience.

Sistemas de información ferroviaria: resultados de un Seminario

Incluye Bibliografía

Práticas do ecodesign no polo de jóias folheadas de Limeira: um estudo de caso

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Metodologia para avaliação de desempenho ambiental em aeroportos e sua aplicação no Aeroporto Internacional de Viracopos, Campinas (SP)

Pós-graduação em Geologia Regional - IGCE

Estratégia competitiva e o papel da função produção: uma análise em empresas do polo calçadista de Birigui

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Las oportunidades y los riesgos en la privatización ferroviaria latinoamericana.

La mayoría de los ferrocarriles latinoamericanos fueron construidos por empresas privadas, muchas veces extranjeras. Luego, por una combinación de factores relacionados con la competencia carretera y el nacionalismo, casi todos llegaron a formar parte del sector gubernmanental, para el cual la administración de los ferrocarriles llegó a constituir un infortunio cada vez mayor, a raíz de los crecientes subsidios que consumieron, el papel progresivamente más reducido que cumplieron en las economías nacionales y una apreciación de que no corresponde a los gobiernos la gestión de actividades productivas. Por lo tanto, a partir de fines del decenio 1980, se inicia un proceso de desestatización ferroviaria, y los ferrocarriles se devuelven a las manos de empresas privadas, muchas veces extranjeras. En ese sentido, el viaje ferroviario latinoamericano, que comenzó hace más de 150 años, está regresando a su punto de partida.No se ha hecho todavía una evaluación de la reciente privatización ferroviaria latinoamericana. Si fuera hecha, probablemente se concluiría: (i) que ha sido bastante exitosa, y; (ii) que sus resultados podrían haber sido aun más positivos si se hubiera modificado algunos detalles de la manera en que se llevara a cabo. Uno de los problemas se relaciona con la no incorporación en los procesos de licitaciones de un reconocimiento de los beneficios por externalidades de los ferrocarriles, por su contribución a la reducción de los costos del mantenimiento de las carreteras y al daño medioambiental asociado con el transporte caminero. Otra materia no resuelta trata de la licitación de un ferrocarril en su totalidad, o de la infraestructura y los servicios de forma separada.La operación de los ferrocarriles está sujeta a la influencia de las economías de escala, que favorecen la integración de diferentes empresas ferroviarias. En el pasado, hubo vínculos a nivel de directorio entre ferrocarrileción de los ferrocarriles. Ahora que la época estatal también se retrocede hacia el pasado, se puede prever la formación de sistemas ferroviarios integrados, uno de los cuales podría extenderse desde Quijarro, en la frontera entre Bolivia y Brasil, hasta la surchilena ciudad de Puerto Montt.

La privatización ferroviaria en América Latina y el Caribe en análisis

La privatización ferroviaria latinoamericana ha logrado alcances importantes, puesto que la situación resultante es mejor a la que se habría producido bajo la gestión y operación por parte de las administraciones estatales. En general, los volúmenes de tráfico han aumentado, aunque con mucha variación entre casos, las subvenciones gubernamentales han disminuido y los índices de productividad se han elevado. Sin embargo, la privatización ferroviaria en América Latina no ha constituido un éxito total, debido a determinadas características de los modelos de privatización adoptados y al entorno del sector transporte dentro del cual los ferrocarriles deben competir.

As múltiplas fontes de renda e a pluriatividade nos bairros Aeroporto, Cedro, Córrego da Onça, Ponte Alta e Gramado no município de Presidente Prudente-SP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)