405 resultados para RELAY


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[L-R: Ray Christensen, John Moule, Jack Carroll, Don McEwen]

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[L-R: Jack Carroll, Bill Konrad, Bill Barton, Bill Hickman]

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[L-R: Jack Carroll,?, Don McEwen, John Ross]

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[L-R: George Vetter, Archie Parsons, Bob Thomason, Ken Doherty, Ross(?) Hume, Bob (?) Hume

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[L-R: DAve Matthews, Ross Hume, John Roxborough Bob Ufer]

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L-R: Wayne Glas, Bob Ufer, Ross Hume, Robert Hume

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L-R: Bob Zann, Tim Norlen, Larry Day, Ray McCullough

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L-R: Howard Donnelly, George Murphy, coach Steve Farrell, H. Leslie Carroll, Clarence Ufer

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In the absence of external stimuli, the mammalian brain continues to display a rich variety of spontaneous activity. Such activity is often highly stereotypical, is invariably rhythmic, and can occur with periodicities ranging from a few milliseconds to several minutes. Recently, there has been a particular resurgence of interest in fluctuations in brain activity occurring at <0.1 Hz, commonly referred to as very slow or infraslow oscillations (ISOs). Whilst this is primarily due to the emergence of functional magnetic resonance imaging (fMRI) as a technique which has revolutionized the study of human brain dynamics, it is also a consequence of the application of full band electroencephalography (fbEEG). Despite these technical advances, the precise mechanisms which lead to ISOs in the brain remain unclear. In a host of animal studies, one brain region that consistently shows oscillations at <0.1 Hz is the thalamus. Importantly, similar oscillations can also be observed in slices of isolated thalamic relay nuclei maintained in vitro. Here, we discuss the nature and mechanisms of these oscillations, paying particular attention to a potential role for astrocytes in their genesis. We also highlight the relationship between this activity and ongoing local network oscillations in the alpha (a; ~8-13 Hz) band, drawing clear parallels with observations made in vivo. Last, we consider the relevance of these thalamic ISOs to the pathological activity that occurs in certain types of epilepsy.