Suomenmaan maan-tieto : [Alexander Gustaf Julius Hallstén] ; suomentanut G. C.

Translated from Swedish into Finnish by Gustaf Cannelin.

Wecksell, Josef Julius

f. 19.3.1838 i Åbo, d. 9.8.1907 i Helsingfors. J.J. Wecksell har gått till litteraturhistorien som poet och dramatiker, bitvis överraskande modern för sin tid. Hans svenskspråkiga diktarbana inleddes kring år 1860 men blev kortvarig pga. psykisk sjukdom. I grunden förblev Wecksell romantisk idealist men vacklar ändå i sin litterära produktion mellan det konventionella och det överraskande moderna och personliga. Motsättningen mellan verklighet och ideal (som framstår som ouppnåeliga) är ett återkommande tema i hans verk. Till hans betydelse bidrar framför allt sorgespelet Daniel Hjort (1862, tryckt 1863), som setts som det främsta historiska dramat i finländsk 1800-talsdramatik, och några av hans dikter som bryter mot konventionerna i den samtida poesin, särskilt dikten På moln stod du (1863), som har antagits vara skriven i Bonn, då Wecksell redan var psykiskt sjuk.

Daniel Hjort: sorgespel i fem akter med fyra tablåer af Josef Julius Wecksell

Första gången uppfördt på Nya Theatern i Helsingfors den 26 november 1862.

Valda ungdomsdikter af Josef Julius Wecksell

Impr.: Carl von Schoultz.

Samlade dikter af Josef Julius Wecksell

Impr.: L. Heimbürger.

The Roman Empire as it was in the time of Julius Caesar and it is described in his Commentaries, and in Silius Italicus

Julkaisussa: Geographia classica : the geography of the ancients

Krohn, Julius

Julius Krohn, som diktare Suonio f. 19.4.1835 i Viborg d. 28.8.1888 i Viborg Julius Krohn har blivit känd som förkämpe för finskheten under 1800-talet. Han var verksam som diktare, professor i finska språket och litteraturen, översättare och tidningsman. Han bidrog till att jämförelsen mellan tidiga versioner av en berättelse blev en etablerad metod i folkdiktningsforskningen, och fick av den anledningen även internationellt erkännande. Krohn utgav själv under namnet Suonio allegoriska sagor, fosterländska dikter och kärlekslyrik. I produktionen ingår också dikter för barn, psalmer och kärleksdikter skrivna till hans hustru, Emma Krohn, efter hennes död. Julius Krohn språkgranskade även Aleksis Kivis klassiska verk Sju bröder och understödde Kivi ekonomiskt, även om de två männen skildes åt i sin syn på diktning, något som kom till uttryck i Kivis sätt att beteckna sin beskyddare som ”lallaa-runoilija” (sv. ung. ”tralala-diktare”). http://www.blf.fi/artikel.php?id=496 http://www.kansallisbiografia.fi/kb/artikkeli/496/

Geological sketch map of New Zealand constructed from official surveys and the explorations of F. von Hochstetter, Julius Haast and others

Kartta kuuluu A. E. Nordenskiöldin kokoelmaan

Long-term ethanol intoxication reduces inflammatory responses in rats

The anti-inflammatory effects of long-term ethanol intoxication were determined during ethanol treatment and withdrawal on the basis of neutrophil and eosinophil migration, hind paw edema and mast cell degranulation. Male Wistar rats (180-200 g, around 2 months of age) were exposed to increasing concentrations of ethanol vapor over a 10-day period. One group was evaluated immediately after exposure (treated group - intoxicated), and another was studied 7 h later (withdrawal group). Ethanol inhalation treatment significantly inhibited carrageenan- (62% for the intoxicated group, N = 5, and 35% for the withdrawal group, N = 6) and dextran-induced paw edema (32% for intoxicated rats and 26% for withdrawal rats, N = 5 per group). Ethanol inhalation significantly reduced carrageenan-induced neutrophil migration (95% for intoxicated rats and 41% for withdrawn rats, N = 6 per group) into a subcutaneous 6-day-old air pouch, and Sephadex-induced eosinophil migration to the rat peritoneal cavity (100% for intoxicated rats and 64% for withdrawn rats, N = 6 per group). A significant decrease of mast cell degranulation was also demonstrated (control, 82%; intoxicated, 49%; withdrawn, 51%, N = 6, 6 and 8, respectively). Total leukocyte and neutrophil counts in venous blood increased significantly during the 10 days of ethanol inhalation (leukocytes, 13, 27 and 40%; neutrophils, 42, 238 and 252%, respectively, on days 5, 9 and 10, N = 7, 6 and 6). The cell counts decreased during withdrawal, but were still significantly elevated (leukocytes, 10%; neutrophils, 246%, N = 6). These findings indicate that both the cellular and vascular components of the inflammatory response are compromised by long-term ethanol intoxication and remain reduced during the withdrawal period.

In vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper

Piplartine {5,6-dihydro-1-[1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-2(1H)pyridinone} and piperine {1-5-(1,3)-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine} are alkaloid amides isolated from Piper. Both have been reported to show cytotoxic activity towards several tumor cell lines. In the present study, the in vivo antitumor activity of these compounds was evaluated in 60 female Swiss mice (N = 10 per group) transplanted with Sarcoma 180. Histopathological and morphological analyses of the tumor and the organs, including liver, spleen, and kidney, were performed in order to evaluate the toxicological aspects of the treatment with these amides. Administration of piplartine or piperine (50 or 100 mg kg-1 day-1 intraperitoneally for 7 days starting 1 day after inoculation) inhibited solid tumor development in mice transplanted with Sarcoma 180 cells. The inhibition rates were 28.7 and 52.3% for piplartine and 55.1 and 56.8% for piperine, after 7 days of treatment, at the lower and higher doses, respectively. The antitumor activity of piplartine was related to inhibition of the tumor proliferation rate, as observed by reduction of Ki67 staining, a nuclear antigen associated with G1, S, G2, and M cell cycle phases, in tumors from treated animals. However, piperine did not inhibit cell proliferation as observed in Ki67 immunohistochemical analysis. Histopathological analysis of liver and kidney showed that both organs were reversibly affected by piplartine and piperine treatment, but in a different way. Piperine was more toxic to the liver, leading to ballooning degeneration of hepatocytes, accompanied by microvesicular steatosis in some areas, than piplartine which, in turn, was more toxic to the kidney, leading to discrete hydropic changes of the proximal tubular and glomerular epithelium and tubular hemorrhage in treated animals.