Análise de fatores clínicos, radiológicos e patológicos que influenciam o tratamento cirúrgico do câncer de mama localmente avançado, submetido à quimioterapia neoadjuvante

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Caracterização do meio físico da bacia do córrego caçula e processos de degradação associados com vistas ao planejamento territorial

Pós-graduação em Engenharia Civil - FEIS

Planejamento de experimentos em blocos aplicado às propriedades mecânicas de arames de aço para molas

The purpose of this article is to demonstrate an application of the design of block experiments via analysis and multiple linear regression in the investigation of a steel thermal treatment process with multiple responses. The study aimed to design statistical models to predict the mechanical properties in SAE 9254 draw steel wires, with diameters of 2.00 mm and 6.50 mm, after quench hardening and tempering. For this purpose, process input variables (wire diameter, processing speed, tempering temperature and polymer concentration) were investigated regarding their influence on the material tensile strength, yield point and hardness. The results revealed that the mechanical properties of the steel wire are significantly influenced by the selected variables, and analysis of variance (ANOVA) was employed to validate the design of the statistical models. Multiple linear regression allowed for an appropriate representation of the process, and graphical analysis was found to be very useful in displaying the behavior of the multiple responses.

Síntese e avaliação farmacológica de novos compostos híbridos úteis para tratamento das complicaçôes da anemia falciforme

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação da dose de radiação absorvida em exames radiológicos durante o planejamento radioterápico

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Sistema de gestão ambiental: subsídios para a implantação em uma estação de tratamento de esgoto a partir da análise crítica de estudos ambientais prévios

The process of environmental impact assessment (EIA), in the extent of previous environmental studies, has as one of its functions to provide subsidies to the actions of environmental managment of enterprises. However, the proper estructuring of programs that allows to support this managment does not often occurs. This research sought as one of its objectives to evaluate in which extent the process of EIA can be a subsidie for the EMS, providing basic elements of this system. In addition, more specifically, the research had as one of its objetives the development of subsidies for the implantation of an Environmental Managment System (EMS), based on the model of ISO 14001 (2004), for a sewage treatment plant yet to be constructed in the city of President Venceslau / SP. In order to achieve theses objetives, a discussion was held based on the evaluation of environmental studies available in the library of Cetesb / SMA. Still, for the elaboration of subsidies for the EMS of the treatment plant, the research was focused on the structuring of environmental management program, based on the information contained in its Preliminary Environmental Report (PER). The research had as one of its products, the development of subsidies for the planning and control of the environmental aspects and impacts and for the environmental program of the enterprise, based on the use of environmental indicators. It was concluded, based on the results that, in general, the previous environmental studies analyzed showed little emphasis on the phase of development of structured environmental programs that offer guidelines to achieve the desired results for the environmental performance of the company.

Recursos humanos e materiais na assistência de enfermagem a pacientes de uma unidade de tratamento de queimaduras

The burn is among the leading causes of morbidity and mortality in our society. It shows a great complexity and is hard to treat. Beyond the physical suffering, the burned patient is affected by psychological distress, requiring a high level of knowledge for assistance planning. The Professional Practice Law No. 7498 establishes the nurse as in charge of the client, as leader of the nursing team and as responsable for the management of physical and human resources. The nurse has autonomy to design the quantitative and qualitative picture of the nursing staff and should use the methodologies for their suitability to the real levels of assistance needed. Material resources represent 15 to 25% of total expenditures at health organizations. Therefore, to maintain the care level, nurses must determine the needs, considering the quantitative, qualitative and financial aspects. The study aimed the survey of the human and material resources necessary for nursing care to patients in a Burns Treatment Unit and identify its epidemiological profile and its nursing diagnoses. We collected the data from medical records of hospitalized between July and August, and the nursing diagnoses were classified through the Taxonomy II proposed by the North American Nursing Diagnosis Association (NANDA). The design of the picture of nurses followed the parameters of COFEN Resolution nº 293/2004. We apply the Fugulin's Patients Classification System to establish levels of the required care. The institution's Cost Center provided a spreadsheet with the purchased items, subsequently classified into ABC. Most hospitalized patients were men, aged between 20 and 50. There was a predominance of patiences with minor burned and the most common type of burn was due to fire. The average residence time was 28.71 days, and 88% of the patients were discharged... (Complete abstract click electronic access below)

Modelos de tratamento para adenocarcinomas de próstata tratados por radioterapia conformacional 3D

Radiotherapy is a branch of medical physics related to the treatment of malignant neoplasm, being an important instrument in the fight against cancer, when combined with the effort of a multidisciplinary team, composed of, physicians, physicists, nurses and technicians. Every year more than 3.5 million new cases of cancer are recorded in the world, being the prostate cancer responsible for approximately 25% of this amount (INCA and IARC, 2008). In this type of cancer, radiotherapy is a method indicated for treatement. The technological advance in this area over years has allowed a greater accuracy in the tumor location, more conformation of the radiation beam around the tumor, reducing the dose in healthy tissues and a consequent dose increase on treatment (Bedford et al., 1999). A radiotherapy planning, in which the physicist develops an important role, is composed of several steps, including choosing the best configuration of treatment beams. This choice has a close relationship with success of therapy and is critical to achieve the best distribution of dose inside the tumor and expose the least as possible the healthy tissue to radiation. In this work, two options for setting up camps in the first phase in a treatment of prostate cancer were simulated in computer planning: 4 fields orthogonal or “Box” with gantry angles in 00, 1800, 2700 e 90° and 4 fields angled or “X” (1350, 450, 3150 e 2250). The percentage of the rectal volume exposed to 40, 50, 60, 72 and 76 Gy should be limited to 60, 50, 25, 15 and 5% respectively (Greco et al., 2003). The femoral toxicity have limited dose by 70% of the total dose prescribed in a prostate treatment (Bedford et al., 1999). The planning of 27 patients with prostate adenocarcinoma submitted to 3D conformal radiotherapy were accompanied. As a result, it was assessed that the best TCP (tumor control probability)... (Complete abstract click electronic access below)

Extração de incisivo inferior: uma alternativa no tratamento da classe III

The correction of a Class III malocclusion in adult patients is one of the major challenges in orthodontics due to facial deformities occurring during the unfavorable growth of this kind of pattern, as well as the treatment options capable of producing facial changes aesthetically acceptable and adequate for today's beauty standards. One acceptable alternative treatment is the removal of a lower incisor. For a Class III correction through a lower incisor extraction a thorough analysis and planning must be carried out by taking into consideration the amount of overjet and overbite, periodontal condition of the teeth and the possibility of obtaining a good dental occlusion with acceptable facial aesthetics. Will be presented two case reports of patients presenting an anteroinferior crowding, Class III malocclusion condition. The treatment through a lower incisor extraction and the reasons why this treatment was adopted will be discussed.

Tratamento ortodôntico da agenesia de incisivo lateral superior com envolvimento de fratura radicular de incisivo central superior

Patients with agenesis of maxillary lateral incisor must have in your planning functional and aesthetic considerations, important to the success of the treatment, regardless of whether the choice of treatment is closing or opening and maintenance of space for rehabilitation with prosthesis. This choice will depend on factors such as skeletal and tooth structure and profile. Children and adolescents are the group of individuals most exposed to trauma and fracture of the maxillary lateral incisor due to the activities they perform. Proper diagnosis and good treatment are essential to the success of the treatment. This article aims to report a case of agenesis of the maxillary lateral incisor along with the involvement of a root fracture of the maxillary central incisor. The orthodontic treatment was successfully finished with a favorable prognosis for the fractured incisor to stay in a esthetic and functional position.

A utilização do enxerto ósseo autógeno para tratamento de lesão de furca grau II

Destruction of bone and periodontal ligament as a result of periodontal disease can lead to anatomical defects in the furcation area. Treatment of these lesions is a major challenge to the clinician. Periodontal instruments have limited access to this area and plaque and calculus removal from root surfaces are extremely difficult. For proper treatment planning a number of factors must be taken into consideration to achieve immediate and long term success. Surgical therapy associated with bone grafts may be a viable option in the treatment of class II furcation defects, aiming to restore lost tissues. The aim of this paper is to report a clinical case where a simplified surgical approach with the use of autogenous graft was used to treat a class II furcation defect Twelve months after the surgery, an increase in clinical attachment level and pocket depth reduction resulted in a complete closure of the furcation lesion.

Interação entre odontologia restauradora e periodontia - parte 1: planejamento e protocolo cirúrgico

Current dental treatments search for alternatives to achieve restablishment of esthetics and function. The increased demand for high esthetic patterns stimulates an interaction between the dental specialties towards a comprehensive treatment in order to solve slinical cases effectively. Knowing the components involved in the dental smile harmony is essential for treatment planning and implementation. It is also important to be aware of the changes that may impair suck harmony and become a patient's complaint. This article addresses a multidisciplinary treatment that involved the integration between Periodontics and Restorative Dentistry. After the surgical-restorative planning, periodontal procedures were performed to obtain an adequate balance between the teeth and soft tiessues.

Estudo do ultrassom de potência no pré-tratamento do material lignocelulósico de resíduos da bananeira

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Implicações da disposição de lodo de estação de tratamento de esgoto em solo no Brasil

The management of solid waste originated from the treatment of domestic and industrial sewage in wastewater treatment plants is a current challenge in the Brazilian reality. However, the planning and the final destination of sludge end up being overlooked, causing serious damage to human health and the environment. The use of sewage sludge in the agriculture is growing in Brazil and is regulated by the Resolução CONAMA Nº 375/2006 which establishes the criteria and parameters so that the sludge can be disposed on the ground safely to the environment and the population. This study aims to define the effects of using sewage sludge in soil according to the results of the bibliographic survey of theoretical and practical studies using this waste in the recovery and conditioning of soil for agriculture and recuperation of degraded areas, and to define whether such type of sludge recycling is environmentally and socially feasible and safe. It can be said that the reuse of sewage sludge in soil meets the search requirements for an alternative that brings agronomic, environmental and economic benefits, as well as being an environmental and social healthy alternative if properly attended the laws that deal with the subject, anyway those should be reviewed and updated taking into account Brazilian soil and climate conditions, thus justifying need for more studies in the area

Planejamento reverso em implantodontia: relato de caso clínico

The oral rehabilitation has achieved great prominence in the dental implant, especially in the cases of reposition of units dental elements, so it is possible to replace each missing element to implant into your space where the tooth was loss. The reverse planning is fundamental to an appropriate rehabilitation, because promote the elimination of problems that might compromise the aesthetics and function of future dental implants. The objective of this study was to report the treatment plan for a patient in need of oral rehabilitation with implant dental prosthesis, using indications and techniques based on the literature, emphasizing the importance of reverse planning. We conducted an osseointegrated implant surgery using the principles of a connect procedure, thus allowing their successfully installing increasing the predictability of treatment. It is concluded that the success of rehabilitation treatment is directly related to the initial planning, a correct clinical approach and an integrated multidisciplinary team.