Gene content phylogeny of herpesviruses

Clusters of orthologous groups [COGs; Tatusov, R. L., Koonin, E. V. & Lipman, D. J. (1997) Science 278, 631–637] were identified for a set of 13 completely sequenced herpesviruses. Each COG represented a family of gene products conserved across several herpes genomes. These families were defined without using an arbitrary threshold criterion based on sequence similarity. The COG technique was modified so that variable stringency in COG construction was possible. High stringencies identify a core set of highly conserved genes. Varying COG stringency reveals differences in the degree of conservation between functional classes of genes. The COG data were used to construct whole-genome phylogenetic trees based on gene content. These trees agree well with trees based on other methods and are robust when tested by bootstrap analysis. The COG data also were used to construct a reciprocal tree that clustered genes with similar phylogenetic profiles. This clustering may give clues to genes with related functions or with related histories of acquisition and loss during herpesvirus evolution.

The resource consumption principle: attention and memory in volumes of neural tissue.

In the cerebral cortex, the small volume of the extracellular space in relation to the volume enclosed by synapses suggests an important functional role for this relationship. It is well known that there are atoms and molecules in the extracellular space that are absolutely necessary for synapses to function (e.g., calcium). I propose here the hypothesis that the rapid shift of these atoms and molecules from extracellular to intrasynaptic compartments represents the consumption of a shared, limited resource available to local volumes of neural tissue. Such consumption results in a dramatic competition among synapses for resources necessary for their function. In this paper, I explore a theory in which this resource consumption plays a critical role in the way local volumes of neural tissue operate. On short time scales, this principle of resource consumption permits a tissue volume to choose those synapses that function in a particular context and thereby helps to integrate the many neural signals that impinge on a tissue volume at any given moment. On longer time scales, the same principle aids in the stable storage and recall of information. The theory provides one framework for understanding how cerebral cortical tissue volumes integrate, attend to, store, and recall information. In this account, the capacity of neural tissue to attend to stimuli is intimately tied to the way tissue volumes are organized at fine spatial scales.

Letter from Fisher Ames to Deborah Ames Shuttleworth, 1805 August 27

One folded sheet containing a two-page letter from Fisher Ames in Dedham, Mass. to his sister "Debby" in Windsor, Vermont. Ames provides updates on the health of his children and individuals in the community, and discusses the summer heat, including mention of the likelihood of dysentery, and his attendance at "Mr. Montagu's Church," referring to the Dedham Episcopal Church presided over by Reverend William Montague.

Franklin County, Massachusetts, 1858 (Image 3 of 3) (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Map of Franklin County, Massachusetts : based upon the trigonometrical survey of the state, the details from actual surveys under the direction of H.F. Walling, supt. of the state map. It was published by Smith & Ingraham in 1858. Scale [ca. 1:47,520]. This layer is image 3 of 3 total images, representing the northeast portion of the four sheet source map. The image inside the map neatline is georeferenced to the surface of the earth and fit to the Massachusetts State Plane Coordinate System, Mainland Zone (in Feet) (Fipszone 2001). All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, railroads, drainage, public buildings, schools, churches, cemeteries, industry locations (e.g. mills, factories, mines, etc.), private buildings with names of property owners, town and school district boundaries, and more. Relief shown by hachures. It includes many cadastral insets of individual county towns and villages. It also includes illustrations, business directories, and tables of statistics and distances.This layer is part of a selection of digitally scanned and georeferenced historic maps of Massachusetts from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of regions, originators, ground condition dates (1755-1922), scales, and purposes. The digitized selection includes maps of: the state, Massachusetts counties, town surveys, coastal features, real property, parks, cemeteries, railroads, roads, public works projects, etc.

Greenfield, Massachusetts 15 Minute Digital Raster Graphic

This layer is a digital raster graphic of the historic 15-minute USGS topographic map of the Greenfield, Massachusetts quadrangle. The survey date (ground condition) of this map is 1886 and 1887; the edition date is September, 1894. A digital raster graphic (DRG) is a scanned image of a U.S. Geological Survey (USGS) standard series topographic map, including all map collar information. The image inside the map neatline is geo-referenced to the surface of the earth and fit to the Universal Transverse Mercator projection. The horizontal positional accuracy and datum of the DRG matches the accuracy and datum of the source map. The names of quadrangles which border this one appear on the map collar in their respective positions (N,S,E,W) in relation to this map.

Warwick, Massachusetts 15 Minute Digital Raster Graphic

This layer is a digital raster graphic of the historic 15-minute USGS topographic map of the Warwick, Massachusetts quadrangle. The survey date (ground condition) of the original paper map is 1887, and the edition date is 1889. A digital raster graphic (DRG) is a scanned image of a U.S. Geological Survey (USGS) standard series topographic map, including all map collar information. The image inside the map neatline is geo-referenced to the surface of the earth and fit to the Universal Transverse Mercator projection. The horizontal positional accuracy and datum of the DRG matches the accuracy and datum of the source map.

UM Men's Swimming Team, 1983

Front Row: head coach Jon Urbanchek, Antonio Cerezo, Antonio Cohen, Benoit R. Clement, John Albanese, Kip Kimble, Bruce M. Gemmell, Kevin V. Williamson, Dave Mason, Bruce Kimball, Sam Lee, diving coach Dick Kimball.

Middle Row: Michael Gruber, Bill Eagan, Mike Fabian, Mike Hsi, Scott McKean, Kent Ferguson, Neal W. Bond, Harry N. Canales, Kirstan A. Vandersluis, Greg Dawkins, Mark Noetzel, Asst. coach Fernando Canales.

Back Row: Marc C. Parrish, Bruce Douglas, Jeff Wriston, Anthony Wallingford, John M. Andres, Roy Horning, Andrew R. Montague, Timothy P. Sheridan, Gary M. Antonick, Mike Mastic, manager Steve Roeder.

UM Men's Swimming Team, 1984

Front Row: Harry Canales, Benoit Clement, Marc Parrish, Kirstan Vandersluis, Andy Montague, Kent Ferguson, Mark Noetzel

2md Row: Tim Sheridan, Gary Antonick, John Andres, Lance Schroeder, Alex Wallingford, Myri Zawoiski, Tim Gardner,

3rd Row: Dave Kerska, Gerhardus Kleyhans, Bruce Kimball, Joe Parker, Marcus DiPietro, Pete Hovard, Paul Kent,

4th Row: Matt Hawthorne, Chris Pelligrino, Rick Hamilton, Paul Schrieter, Gary Pyle, Jim Caffrey, Peter Holmquist

Back Row: Jeff Gordon, Randall Murphy, Tom Cobau, Jim Bruzzese

Miss Eliza Rossell : a tale of the unfortunate female /

Wright I, 1879.

The building of the intellect: a contribution towards scientific method in education.

Mode of access: Internet.

Paris de Monmartel (Jean) banquier de la cour, receveur des rentes de la ville de Paris, 1690-1766. : Origine et vie des frères Paris, munitionnaires des vivres et financiers. Les logis de Monmertel.

Bibliography: pages [335]-342.

Outlines for the study of art /

Contains bibliographies.

The five jars,

Mode of access: Internet.

The manuscripts in the library at Lambeth palace.

Mode of access: Internet.