Desarrollo para internet con tecnología JAVA

L'objectiu d'aquest projecte és l'aprenentatge de la tecnologia Java per a desenvolupar aplicacions a Internet. Per a aprofundir en l'ús de les tecnologies J2EE, s'ha fet una aplicació pràctica anomenada 'Parfumsnet'; que implementa un centre virtual.

Desenvolupament d'aplicacions per a Internet amb Tecnologia JAVA : Projecte Xhelp OutsourcingService

L'objectiu d'aquest TFC ha estat desenvolupar una eina de gestió de projectes de manteniment de programari que oferís la possibilitat d'enregistrar i controlar la qualitat del servei que es dóna al client en una empresa consultora de programari.

Desarrollo de un framework de Persistencia paratecnología Java : WayPersistence ORM

Les característiques imprescindibles per a qualsevol framework desenvolupat de forma personalitzada són: escalabilitat i multiplataforma, adaptabilitat a qualsevol sistema gestor de base de dades, vàlid per a qualsevol tipus de base de dades (relacional, en xarxa, jeràrquica, etc.) i fàcil maneig i simplicitat per a l'equip de desenvolupament. En el nostre WayPersistence v1.0 està validat per base de dades relacionals en un principi, millorable en versions posteriors.

Disseny i implementació en Java d'un sistema segur de descàrrega anònima de fitxers format per aplicacions web basades en XML i amb autenticació del client per part d'un tercer mitjançant una PKI

En aquest TFC s'ha proposat dissenyar i implementar en llenguatge Java un sistema segur de descàrrega anònima de fitxers. Per fer aquesta tasca es proposa un conjunt d'aplicacions web que es s'intercanviaran dades en format XML de forma segura, sempre sota protocol HTTPS i mantenint la integritat, autenticitat i autenticació de les parts amb l'ajut d'un PKI.

Gestió d'una cooperativa de taxis emprant tecnologies Java

En aquest treball de final de carrera es proposa la creació d'un sistema per a gestionar d'una manera molt més eficaç els processos de treball d'una cooperativa de taxis, mitjançant la instal·lació d'equips GPS en els taxis i la implementació d'eines informàtiques que automatitzin i optimitzin el procés de designació.

Inmuebles : portal de anuncios inmobiliarios en Java EE

Definición, análisis, diseño e implementación de un portal basado en la arquitectura Java EE que sintetiza los conocimientos adquiridos en la carrera de Ingeniería Técnica de Sistemas cursada en la UOC.

Comparación de analizadores estáticos para código java

El objetivo principal de este artículo es la selección y comparación de dos herramientas de análisis estático para java, esta tarea necesita de estudiar previamente el estado del arte de estos analizadores, ver qué características son deseables para este tipo de analizadores y finalmente compararlas en ejecución sobre los dos proyectos de software libre elegidos argoUML y openProj. Se compara FindBugs con PMD, dos analizadores que pueden utilizarse con la versión 1.6. de JDK. Los resultados de la comparación nos permiten deducir que los analizadores se complementan en cuanto a bugs detectados, hay pocos solapamientos. Como conclusiones podemos decir que la búsqueda de bugs necesita de más de una herramienta de análisis estático.

The utility of the polymerase chain reaction assay for aetiologic definition of unspecified bacterial meningitis cases

Most patients with acute suppurative meningitis are otherwise healthy individuals with regard to immune mechanisms against invasive bacterial disease. This medical emergency is among the most dramatic and potentially ravaging diseases that affect humans, particularly young children. The illness often strikes suddenly, and can either result in death or leave the survivors with significant neurological dysfunctions. The demonstration of a bacterial aetiology is necessary for decisions regarding treatment and prophylaxis. Conventional bacteriological methods frequently fail to identify an agent, as a result of administration of antibiotics or delayed lumbar punctures. We investigated the major aetiologic sources of unspecified bacterial meningitis cases (G00.9, ISCD-10) by polymerase chain reaction (PCR)-based identification of Neisseria meningitidis (crgA), Streptococcus pneumoniae (ply) and Haemophilus influenzae (bexA) in cerebrospinal fluid samples. The multiplex PCR detected N. meningitidis in 92%, S. pneumoniae in 4% and H. influenzae in 1% of the 192 clinical samples assayed; 3% were negative for all three DNA targets. Bacterial DNA detection was found to be a valuable adjunct to enhance bacterial meningitis surveillance when the yield of specimens by culture is reduced. The implementation of PCR assays as a diagnostic procedure in Public Health Laboratories is perceived to be a significant advance in the investigation of bacterial meningitis.

The utility of rhesus monkey (Macaca mulatta) and other non-human primate models for preclinical testing of Leishmania candidate vaccines

Leishmaniasis causes significant morbidity and mortality, constituting an important global health problem for which there are few effective drugs. Given the urgent need to identify a safe and effective Leishmania vaccine to help prevent the two million new cases of human leishmaniasis worldwide each year, all reasonable efforts to achieve this goal should be made. This includes the use of animal models that are as close to leishmanial infection in humans as is practical and feasible. Old world monkey species (macaques, baboons, mandrills etc.) have the closest evolutionary relatedness to humans among the approachable animal models. The Asian rhesus macaques (Macaca mulatta) are quite susceptible to leishmanial infection, develop a human-like disease, exhibit antibodies to Leishmania and parasite-specific T-cell mediated immune responses both in vivo and in vitro, and can be protected effectively by vaccination. Results from macaque vaccine studies could also prove useful in guiding the design of human vaccine trials. This review summarizes our current knowledge on this topic and proposes potential approaches that may result in the more effective use of the macaque model to maximize its potential to help the development of an effective vaccine for human leishmaniasis.

The utility of anti-trypomastigote lytic antibodies for determining cure of Trypanosoma cruzi infections in treated patients: an overview and perspectives

In previous work, we proposed alternative protocols for following patients with treated Chagas disease and these are reviewed herein. Evidence was provided to support the following: (i) functional anti-trypomastigote antibodies are indicative of ongoing chronic Trypanosoma cruzi infections; (ii) specific antibodies detected by conventional serology (CS) with epimastigote extracts, fixed trypomastigotes or other parasite antigens may circulate years after parasite elimination; (iii) functional antibodies are evidenced by complement-mediated lysis of freshly isolated trypomastigotes, a test which is 100% specific, highly sensitive, and the first to revert after T. cruzi elimination and (iv) the parasite target for the lytic antibodies is a glycoprotein of high molecular weight (gp160) anchored at the parasite surface. The complement regulatory protein has been cloned, sequenced and produced as a recombinant protein by other groups and is useful for identifying functional anti-T. cruzi antibodies in ELISA tests, thus dispensing with the need for live trypomastigotes to manage treated patients. If used instead of CS to define cures for Chagas patients, ELISA will avoid unnecessary delays in finding anti-T. cruzi drugs. Other highly sensitive techniques for parasite DNA detection, such as PCR, need to be standardized and included in future protocols for the management of patients with drug-treated Chagas disease.

Analysis and regeneration of hypermedia contents through Java and XML tools

This paper presents a tool for the analysis and regeneration of Web contents, implemented through XML and Java. At the moment, the Web content delivery from server to clients is carried out without taking into account clients' characteristics. Heterogeneous and diverse characteristics, such as user's preferences, different capacities of the client's devices, different types of access, state of the network and current load on the server, directly affect the behavior of Web services. On the other hand, the growing use of multimedia objects in the design of Web contents is made without taking into account this diversity and heterogeneity. It affects, even more, the appropriate content delivery. Thus, the objective of the presented tool is the treatment of Web pages taking into account the mentioned heterogeneity and adapting contents in order to improve the performance on the Web

Susceptibility of Mycobacterium tuberculosis to first-line antimycobacterial agents in a Brazilian hospital: assessing the utility of the tetrazolium (MTT) microplate assay

We conducted a cross-sectional, hospital-based study between January 2006-March 2008 to estimate the resistance of Mycobacterium tuberculosis to first-line drugs in patients with tuberculosis at a Brazilian hospital. We evaluated the performance of the [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide] (MTT) microplate assay compared with the Bactec-MGIT 960™ system for mycobacteria testing. The prevalence of resistance in M. tuberculosis was 6.7%. Multidrug-resistance [resistance to rifampicin (RMP) and isoniazid (INH)], INH-resistance and streptomycin (SM)-resistance accounted for 1%, 3.8% and 3.8% of all resistance, respectively, and all isolates were susceptible to ethambutol (EM). The resistance was primary in four cases and acquired in three cases and previous treatment was associated with resistance (p = 0.0129). Among the 119 M. tuberculosis isolates, complete concordance of the results for INH and EM was observed between the MTT microplate and Bactec-MGIT 960TM methods. The observed agreement for RMP was 99% (sensitivity: 90%) and 95.8% for SM (sensitivity 90.9%), lower than those for other drugs. The MTT colourimetric method is an accurate, simple and low-cost alternative in settings with limited resources.

Easy Java web application development

El projecte que es descriu en aquest document consisteix en el desenvolupament d'una arquitectura de suport per a aplicacions web empresarials basada en tecnologia J2EE. La idea és gestionar totes les funcionalitats de baix nivell per tal que el desenvolupador de l'aplicació web pugui centrar-se quasi exclusivament en implementar els temes funcionals.

Utility of the mini-cog for detection of cognitive impairment in primary care: data from two spanish studies.

Objectives. To study the utility of the Mini-Cog test for detection of patients with cognitive impairment (CI) in primary care (PC). Methods. We pooled data from two phase III studies conducted in Spain. Patients with complaints or suspicion of CI were consecutively recruited by PC physicians. The cognitive diagnosis was performed by an expert neurologist, after formal neuropsychological evaluation. The Mini-Cog score was calculated post hoc, and its diagnostic utility was evaluated and compared with the utility of the Mini-Mental State (MMS), the Clock Drawing Test (CDT), and the sum of the MMS and the CDT (MMS + CDT) using the area under the receiver operating characteristic curve (AUC). The best cut points were obtained on the basis of diagnostic accuracy (DA) and kappa index. Results. A total sample of 307 subjects (176 CI) was analyzed. The Mini-Cog displayed an AUC (±SE) of 0.78 ± 0.02, which was significantly inferior to the AUC of the CDT (0.84 ± 0.02), the MMS (0.84 ± 0.02), and the MMS + CDT (0.86 ± 0.02). The best cut point of the Mini-Cog was 1/2 (sensitivity 0.60, specificity 0.90, DA 0.73, and kappa index 0.48 ± 0.05). Conclusions. The utility of the Mini-Cog for detection of CI in PC was very modest, clearly inferior to the MMS or the CDT. These results do not permit recommendation of the Mini-Cog in PC.