A skeleton of Astrapotherium / by Elmer S. Riggs --

v.6:no.13(1935)

Controlling Hox gene expression and activity to build the vertebrate axial skeleton

It has long been known that Hox genes are central players in patterning the vertebrate axial skeleton. Extensive genetic studies in the mouse have revealed that the combinatorial activity of Hox genes along the anterior-posterior body axis specifies different vertebral identities. In addition, Hox genes were instrumental for the evolutionary diversification of the vertebrate body plan. In this review, we focus on fundamental questions regarding the intricate mechanisms controlling Hox gene activity. In particular, we discuss the functional relevance of the precise timing of Hox gene activation in the embryo. Moreover, we provide insight into the epigenetic regulatory mechanisms that are likely to control this process and are responsible for the maintenance of spatially restricted Hox expression domains throughout embryonic development. We also analyze how specific features of each Hox protein may contribute to the functional diversity of Hox family. Altogether, the work reviewed here further supports the notion that the Hox program is far more complex than initially assumed. Exciting new findings will surely emerge in the years ahead.

Bones and I; or, The skeleton at home,

Mode of access: Internet.

Skeleton of justice,

"The product of collaboration between Edith Roper, who brought to America her own records, set down while she was newspaper correspondent for several years in the Nazi courts, and Clara Leiser, who rendered into English and helped arrange these records for the American reader, including occasional comments of her own."--p. [2]

Skeleton outline of a plan for developing the Delta-Mendota irrigation water supply and salt-water repulsion in the Sacramento-San Joaquin Delta Region, Central Valley Project, California /

Mode of access: Internet.

An analysis and summary of Thucydides : with a chronological table of principal events, money, distances, etc. reduced to English terms; a skeleton outline of the geography; abstracts of all the speeches, index, etc. /

Mode of access: Internet.

Skeleton construction in buildings : with numerous practical illustrations of high buildings /

Mode of access: Internet.

The explanation of Albinus's anatomical figures of the human skeleton and muscles : with an historical account of the work /

Mode of access: Internet.

MacDonald's skeleton mining report ...

"This skeleton form of report was framed to assist practical Miners and Mine Owners ... in making a comprehensive report"--T.p.