Association of the "major histocompatibility complex subregion" I-J determinant with bioactive glycosylation-inhibiting factor.

Murine suppressor T-cell hybridoma cells (231F1) secrete not only bioactive glycosylation-inhibiting factor (GIF) but also an inactive peptide comparable to bioactive GIF peptide in its molecular size and reactivity with anti-GIF; the amino acid sequence of the inactive peptide is identical to that of the bioactive homologue. The inactive GIF peptide in culture supernatant of both the 231F1 cells and a stable transfectant of human GIF cDNA in the murine suppressor T hybridoma selectively bound to Affi-Gel 10, whereas bioactive GIF peptides from the same sources failed to bind to the gel. The inactive cytosolic human GIF from the stable transfectant and Escherichia coli-derived recombinant human GIF also had affinity for Affi-Gel 10. Both the bioactive murine GIF peptide from the suppressor T hybridoma and bioactive recombinant human GIF from the stable transfectant bound to the anti-I-J monoclonal antibody H6 coupled to Affi-Gel. However, bioactive hGIF produced by a stable transfectant of human GIF cDNA in BMT10 cells failed to be retained in H6-coupled Affi-Gel. These results indicate that the I-J specificity is determined by the cell source of the GIF peptide and that the I-J determinant recognized by monoclonal antibody H6 does not represent a part of the primary amino acid sequence of GIF. It appears that the epitope is generated by a posttranslational modification of the peptide.

Habes humane lector, Gabrielis de Tarrega ... opera breuissima, theorica[m] et prathica[m], medicinalis scie[n]tie pro maiori parte amplexa[n]tia facili ingeniosoq[ue] stillo per ipsum accumulata, medicis instrue[n]dis vtilissima ...

Fecha tomada del colofón en M4v de la cuarta secuencia

Abyssal community analysis from replicate box cores in the central North Pacific

A 0.25 m**2 United States Naval Electronics Laboratory box corer was used to take replicate samples from an oligotrophic bottom under the North Pacific Central Water Mass (~28°N, 155°W). The bottom is a red clay with manganese nodules at a depth of 5500-5800 m. Macrofaunal density ranges from 84 to 160 individuals per m**2 and is therefore much the same as in Northwest Atlantic Gyre waters. Of the macrofaunal taxa, polychaetes dominate (55 %), followed by tanaids (18 %), bivalves (7 %), and isopods (6 %). Meiofaunal taxa were only partially retained by the 297 µm screen used in washing. Even then, they are 1.5-3.9 times as abundant as the macrofaunal taxa, with nematodes being numerically dominant by far. Foraminifera seem to comprise an important portion of the community, but could not be assessed accurately because of the inability to discriminate living and dead tests. Remains of what are probably xenophyophoridans are also very important, but offer the same problem. Faunal diversity is extremely high, with deposit feeders comprising the overwhelming majority. Most species are rare, being encountered only once. The distributions of only three species show any significant deviation from randomness. The polychaete fauna from box cores collected from 90 miles to the north was not significantly different from that of the principal study locality. Concordance appeared at several taxonomic levels, from species through macrofaunal/meiofaunal relationships. As a result, the variation in total animal abundance shows aggregation among cores. We discuss Sokolova's concept of a deep-sea oligotrophic zone dominated by suspension feeders, and reconcile it with our present findings. The high diversity of the fauna combined with the low food level contradict theories that relate diversity directly with productivity.

(Table 2) Radiocarbon age determination from the polar planktonic foraminifera Neogloboquadrina pachyderma s for sediment core HU90-013-029

An additional Heinrich ice-rafting event is identified between Heinrich events 5 and 6 in eight cores from the Labrador Sea and the northwest Atlantic Ocean. It is characterized by sediment rich in detrital carbonate (40% CaCO3) with high concentration of floating dropstones, high coarse-fraction (% > 150 µm) content, and has a sharp contact with the underlying but grades into the overlying hemipelagic sediment. It also shows lighter d18ONpl values, indicating freshening due to iceberg rafting and/or meltwater discharge. This event is correlated with Dansgaard-Oeschger event 14 and interpreted as an additional Heinrich event, H5a. The thickness of H5a in the Labrador Sea reaches up to 220 cm. This additional Heinrich event has also been reported in cores PS2644 and SO82-5 from the northern North Atlantic. With the recognition of H5a the temporal spacing between Heinrich events 1 to 6 becomes more uniform (~7 ka).

What you ought to know about your baby /

All ghost-written by H.L. Mencken except the questions and answers. cf. Schrader.

Margarita poetica : non solum poesim, sed medullam artis rhetoricae : oratorum & historiarum omniu[m]q[ue] humanitatis litterarum completens.

Mode of access: Internet.

R.P. Iacobi Granado ... In tertiam partem S. Thomae Aquinatis commentarii : in duos tomos distincti, quartum scilicet [et] quintum, a quaestione prima vsque ad vltimam et additionibus á q.1 ad 20 [et] à 25 vsque ad 40 [et] à 69 vsque ad ultimam : quibus tres indices adiecti sunt ...

"Panegyricus funebris P. Georgii Hemelman ... Societatis Iesu ... in obitum ... P. Iacobi Granadi...", 50 p.

Diodori Siculi Scriptoris graeci libri duo : primus de Philippi Regis Macedoniae aliorumq[ue] quorundam illustrium ducum, alter de Alexandri filii rebus gestis /

Mode of access: Internet.

Difesa della lingua italiana.

ICCU,

Memoirs of a Magdalen or The history of Louisa Mildway : now first published from a series of original letters, in two volumes ; vol.I [-II]

Mode of access: Internet.

Mantissa decisionum Sacrae Rotae Romanae ad Theatrum veritatis et justitiae eminentissimi D. Cardinalis de Luca eiusque tractatus De officiis venal. et stat. successionibus ... : pars prima.

Mode of access: Internet.

Les presentes heures a lusaige de Ro[m]me au long sans require.

Almanaque de los años 1502-1520, en verso de la portada.

Margarita philosophica noua : cui annexa sunt sequentia Grecarum literarum institutiones Hebraicarum literarum rudimenta Architecture rudimenta Quadrantum varie compositiones ... Cartha vniuersalis terre marisque formam neoterica descriptione indicans

"Appendix matheseos in Margarita[m] philosophicam." (p. [521]-[660])

Gerardi Blasii Amstelodamensis Observationes medicae rariores. Accedit Monstri triplicis historia.

Contiene con paginación y portadilla propia: "Historia infantis monstrosi / D. Michaele Heiland ..., 1676, en p. 1-54 ; Historia agni monstrosi / a ... Mauritio Hoffmanno, en p. 55-62 ; Historia vituli monstrosi / a ... Mauritio Hoffmanno, en p. 63-71"

Breve ragguaglio in forma di lettera della vita del servo di Dio Padre Martino d'Andres Perez ... /

Mode of access: Internet.