Notizie spettanti a corpo di S. Feliciano martire, scoperto nel cimitero di Priscilla, 1666.

"Appendix monumentorum," pp.lvii.

Daily meditations: or, Quotidian preparations for and considerations of death and eternity begun July 19. 1666 /

"A postscript to the reader."--p. [17-18], in verse; signed: M.J. [i.e., Marmaduke Johnson]. In the first issue (1668; Evans 128) the identical postscript is signed: J.T.

Das Processverfahren gegen den kursachsischen Kanzler Dr. Nicolaus Krell 1591 bis 1601 : Dargestellt nach den Akten des Dresdener Haupt-Staats-Archvis.

Thesis (doctoral)--Vereinigte Friedrichs-Universitat, Halle-Wittenberg.

The comedies, histories, and tragedies of Mr. William Shakespeare as presented at the Globe and Blackfriars Theatres, circa 1591-1623 : being the text furnished the players, in parallel pages with the first revised folio text, with critical introductions : the Bankside Shakespeare /

"Five hundred copies only"--V. 1, p. [43].

Die Gegenreformation im Bistum Bamberg unter Furstbischof Neithard von Thungen 1591-98.

Thesis (doctoral)--Friedrich-Alexanders-Universitat Erlangen.

The visitation of the county of Lincoln made by Sir Edward Bysshe, knight, Clarenceux king of arms, in the year of Our Lord 1666 /

Mode of access: Internet.

Tragicomedia de Polidoro y Casandrina (Ms. II-1591 de la Real Biblioteca) edición y estudio

La Tragicomedia de Polidoro y Casandrina nos era completamente desconocida hasta que el manuscrito único en el que se nos ha conservado fue descubierto por Stefano Arata en la Real Biblioteca de Madrid en 1988. Arata [1988] dio entonces noticia de su hallazgo en un breve pero sustancioso artículo publicado en la revista Celestinesca, donde adscribió la obra al ciclo literario que conforman las continuaciones directas de la Celestina y, dado que el códice nos la presenta anónima y sin título, la bautizó con el que todavía mantiene.1 Hizo además un primer análisis codicológico y paleográfico, y, a partir de la alusión a la conquista del peñón de Vélez de la Gomera por don García de Toledo (V, f. 32r), situó su redacción en los años siguientes a 1564.2 En fin, aprovechó para anunciar que estaba preparando una edición del texto. Como «proyecto actual» (PA), aparece explícitamente mencionada en la ficha correspondiente al estudioso sici-liano del Anuario áureo II (Gorsse, Jammes y Vitse, 1990: 13-14), mientras que en el Anuario áureo III parece esconderse bajo un marbete más genérico: «La Celestina y el teatro del siglo XVI» (Jammes, Mir y Vitse, 1993: 16). No sabemos si acabó abandonan-do el proyecto o si los otros muchos trabajos que se le fueron cruzando le impidieron concluir este, pero, cuando la muerte le sobrevino infaustamente en 2001 (cf. Pedrosa, 2001), su Polidoro aún no se había publicado. En 2009, le pedí a mi directora de tesis, Ana Vian Herrero, que intercediese por mí ante Laura Arata para que me permitiera consultar los documentos que conservase de las investigaciones de su hermano sobre la Tragicomedia; Laura nos respondió rápida y amabilísimamente, pero su búsqueda en los archivos de Stefano había sido infructuosa: no quedaba nada. Tras la nota de Arata, el siguiente acercamiento a nuestra obra se debe a Vian Herrero [1997: 228-238], quien la incluyó en un estudio sobre el funcionamiento del conjuro amatorio en la Celestina y sus continuaciones trágicas, es decir, aquellas que tienen un final desgraciado.

Fragmentos inéditos sobre los indios de Tucurrique en 1591: una fuente valiosa par el estudio de la Historia Colonial de Costa Rica

Introducción El estudio de la dinámica social de los cacicazgos costarricenses y su desestructuración como consecuencia de la conquista española se ve muchas veces obstaculizado por la escasa información disponible. Las fuentes escritas primarias son relativamente pocas y se  encuentran en su mayoría publicadas en colecciones de documentos, lo que ha representado una valiosa ayuda a los estudiosos del periodo. Sin embargo, siempre quedan lagunas de información sobre temas específicos que son esenciales para el investigador. Por eso el descubrimiento de datos que nos e conocían ni se habían publicado constituye un feliz y  afortunado acontecimiento. Tal  es la situación que hoy nos motiva a incluir  en estas páginas algunos fragmentos inéditos de un  documento fundamental par el estudio de las sociedades indígenas costarricenses del Valle Central a finales  del siglo XV.

Measuring episodic memory: A novel approach with an indefinite number of alternative forms

Both clinical practice and clinical research settings can require successive administrations of a memory test, particularly when following the trajectory of suspected memory decline in older adults. However, relatively few verbal episodic memory tests have alternative forms. We set out to create a broad based memory test to allow for the use of an essentially unlimited number of alternative forms. Four tasks for inclusion in such a test were developed. These tasks varied the requirement for recall as opposed to recognition, the need to form an association between unrelated words, and the need to discriminate the most recent list from earlier lists, all of which proved useful. A total of 115 participants completed the battery of tests and were used to show that the test could differentiate between older and younger adults; a sub-sample of 73 participants completed alternative forms of the tests to determine test-retest reliability and the amount of learning to learn.

Exercise alone is not enough : weight loss also needs a healthy (Mediterranean) diet?

Objective: In the majority of exercise intervention studies, the aggregate reported weight loss is often small. The efficacy of exercise as a weight loss tool remains in question. The aim of the present study was to investigate the variability in appetite and body weight when participants engaged in a supervised and monitored exercise programme. ---------- Design: Fifty-eight obese men and women (BMI = 31·8 ± 4·5 kg/m2) were prescribed exercise to expend approximately 2092 kJ (500 kcal) per session, five times a week at an intensity of 70 % maximum heart rate for 12 weeks under supervised conditions in the research unit. Body weight and composition, total daily energy intake and various health markers were measured at weeks 0, 4, 8 and 12. ---------- Results: Mean reduction in body weight (3·2 ± 1·98 kg) was significant (P < 0·001); however, there was large individual variability (−14·7 to +2·7 kg). This large variability could be largely attributed to the differences in energy intake over the 12-week intervention. Those participants who failed to lose meaningful weight increased their food intake and reduced intake of fruits and vegetables. ---------- Conclusion: These data have demonstrated that even when exercise energy expenditure is high, a healthy diet is still required for weight loss to occur in many people.

Correlating vehicle forces and track profile

A research project was conducted at Queensland University of Technology on the relationship between the forces at the wheel-rail interface in track and the rate of degradation of track. Data for the study was obtained from an instrumented vehicle which ran repeatedly over a section of Queensland Rail's track in Central Queensland over a 6-month period. The wheel-rail forces had to be correlated with the elements of roughness in the test track profile, which were measured with a variety of equipment. At low frequencies, there was strong correlation between forces and profile, as expected, but diminishing correlation as frequencies increased.

Predicting adolescents’ use of social networking sites from an extended theory of planned behaviour perspective

The popularity of social networking sites (SNSs) among adolescents has grown exponentially, with little accompanying research to understand the influences on adolescent engagement with this technology. The current study tested the validity of an extended theory of planned behaviour model (TPB), incorporating the additions of group norm and self-esteem influences, to predict frequent SNS use. Adolescents (N = 160) completed measures assessing the standard TPB constructs of attitude, subjective norm, perceived behavioural control (PBC), and intention, as well as group norm and self-esteem. One week later, participants reported their SNS use during the previous week. Support was found for the standard TPB variables of attitude and PBC, as well as group norm, in predicting intentions to use SNS frequently, with intention, in turn, predicting behaviour. These findings provide an understanding of the factors influencing frequent engagement in what is emerging as a primary tool for adolescent socialisation.

Formalin fixation affects equilibrium partitioning of an ionic contrast agent-microcomputed tomography (EPIC-[mu]CT) imaging of osteochondral samples

Equilibrium Partitioning of an Ionic Contrast agent with microcomputed tomography (EPIC-[mu]CT) is a non-invasive technique to quantify and visualize the three-dimensional distribution of glycosaminoglycans (GAGs) in fresh cartilage tissue. However, it is unclear whether this technique is applicable to already fixed tissues. Therefore, this study aimed at investigating whether formalin fixation of bovine cartilage affects X-ray attenuation, and thus the interpretation of EPIC-[mu]CT data.Design Osteochondral samples (n = 24) were incubated with ioxaglate, an ionic contrast agent, for 22 h prior to [mu]CT scanning. The samples were scanned in both formalin-fixed and fresh conditions. GAG content was measured using a biochemical assay and normalized to wet weight, dry weight, and water content to determine potential reasons for differences in X-ray attenuation.Results The expected zonal distribution of contrast agent/GAGs was observed for both fixed and fresh cartilage specimens. However, despite no significant differences in GAG concentrations or physical properties between fixed and fresh samples, the average attenuation levels of formalin-fixed cartilage were 14.3% lower than in fresh samples.Conclusions EPIC-[mu]CT is useful for three-dimensional visualization of GAGs in formalin-fixed cartilage. However, a significant reduction in X-ray attenuation for fixed (compared to fresh) cartilage must be taken into account and adjusted for accordingly when quantifying GAG concentrations using EPIC-[mu]CT.

The FAM deubiquitylating enzyme localizes to multiple points of protein trafficking in epithelia, where it associates with E-cadherin and β-catenin

Ubiquitylation is a necessary step in the endocytosis and lysosomal trafficking of many plasma membrane proteins and can also influence protein trafficking in the biosynthetic pathway. Although a molecular understanding of ubiquitylation in these processes is beginning to emerge, very little is known about the role deubiquitylation may play. Fat Facets in mouse (FAM) is substrate-specific deubiquitylating enzyme highly expressed in epithelia where it interacts with its substrate, β-catenin. Here we show, in the polarized intestinal epithelial cell line T84, FAM localized to multiple points of protein trafficking. FAM interacted with β-catenin and E-cadherin in T84 cells but only in subconfluent cultures. FAM extensively colocalized with β-catenin in cytoplasmic puncta but not at sites of cell-cell contact as well as immunoprecipitating with β-catenin and E-cadherin from a higher molecular weight complex (~500 kDa). At confluence FAM neither colocalized with, nor immunoprecipitated, β-catenin or E-cadherin, which were predominantly in a larger molecular weight complex (~2 MDa) at the cell surface. Overexpression of FAM in MCF-7 epithelial cells resulted in increased β-catenin levels, which localized to the plasma membrane. Expression of E-cadherin in L-cell fibroblasts resulted in the relocalization of FAM from the Golgi to cytoplasmic puncta. These data strongly suggest that FAM associates with E-cadherin and β-catenin during trafficking to the plasma membrane.