Perfis hematológico, hepático, lipídico e lipoprotéico de cães (Canis familiaris) com doença hepática

Pós-graduação em Medicina Veterinária - FMVZ

Doença de von Willebrand em cães: estudo da prevalência e caracterização da doença em cães normais e fêmeas durante o ciclo estral, gestação e lactação

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Formação de classes funcionais em cães domésticos (Canis familiaris)

O presente estudo investigou a possibilidade de ensinar dois cães domésticos (Canis familiaris) a responderem adequadamente a duas classes de três estímulos (caixas contendo pedaço de alimento quando com função positiva) através de um procedimento de mudanças sucessivas de discriminação simples (MSDS). A coleta de dados foi realizada em uma sala na qual duas, quatro ou seis caixas de madeira eram dispostas lado a lado, em posições fixas. Inicialmente, os sujeitos responderam a dois estímulos por sessão (um positivo[S+] e outro negativo[S-]), até que quatro das seis caixas apareciam com ambas as funções. Na fase seguinte, as quatro caixas foram apresentadas juntas, de maneira que duas caixas de uma classe eram S+ e as outras duas S-. Foram realizadas mudanças de função até que os sujeitos alcançassem o critério de aprendizagem em 11 de 12 sessões. Em seguida os sujeitos foram expostos a uma sessão ao reforçamento de respostas nas duas caixas ainda não utilizadas e depois a um treino de discriminação simples com as seis caixas. Foi realizado um teste consistindo em uma sessão de mudança com quatro caixas, após a qual eram re-inseridas as duas caixas restantes na sala experimental. Com os resultados negativos obtidos nesse teste, foi realizado um treino de MSDS com as seis caixas, após o qual o teste foi refeito. Ambos os sujeitos responderam adequadamente a todas as tentativas. Outros cinco testes foram realizados com as demais caixas, no mesmo formato do primeiro teste. Um sujeito respondeu adequadamente a dois desses cinco testes e o outro a três deles. Discute-se os efeitos da ênfase na discriminação visual e o uso de posições fixas das caixas sobre o desempenho dos sujeitos.

Estudo comparativo entre anestesia venosa total alvo-controlada e por infusão contínua em cães pré-tratados com levomepromazina e tratados com propofol e remifentanila

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeitos da dexmedetomidina em rins isquêmicos e sobre a concentração plasmática do hormônio antidiurético: estudo experimental em cães anestesiados e hipovolêmicos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Toxicidade do dimetilsulfóxido em cães hígidos e doentes renais crônicos

The objective of this study was to evaluate the effects of dimethyl sulfoxide (DMSO) treatment on aspects of renal function, serum profile, total blood count parameters and clinical condition of health or chronic kidney disease (CKD) dogs. The evaluations were done before, during and after the administration of DMSO 10% at a dose of 0.5g kg-1, each 24h, for three days. DMSO resulted in some adverse effects in both healthy and CKD dogs, however the effects were more frequent and worse in CKD dogs. Despite these adverse effects, both groups don't have contraindications to use the drug in a short time. The severity of adverse effects related to the DMSO and its possible association with death in stage 4 CKD dogs, are contraindications for the drug in this group of patients.

Avaliação cinemática em cães: revisão

Kinematics is the geometry of motion, including displacement, speed and acceleration, without considering the forces acting over a body. The use of kinematics is still very limited when we are evaluating dogs because of the high cost of the equipment, but the information obtained is objective and precise, what is essential for a trustful evaluation. Taking all this into consideration, this evaluation will describe some researches that used the method, specifying the final objective for each of them. By this analysis, we can conclude that kinematic studies, according to the characteristics of dog races, are necessary to explain how body structure and conformance may affect the function. Besides that, according to normative patterns of a population it is possible to study some diseases and treatment evolution

Acupuntura no tratamento de discopatias intervertebrais em cães

The intervertebral disc disease is considered a major neurological disorder involving the spinal cord, being a disease commonly seen in dogs in clinical practice of small animals. The pathophysiology of most discopathies have not been fully elucidated, but it is known that the symptoms observed will depend on the severity of spinal cord compression and location of spinal injury, ranging from localized pain to complete paralysis. Through a detailed clinical examination and laboratory tests, we choose the most appropriate treatment for each patient, which can be conservative, through the use of anti-inflammatories, analgesics and acupuncture or surgical, through decompression techniques. Acupuncture, therapeutic method of ancient Chinese medicine, uses the stimulation of specific points on the body in order to balance the body's physiological. The action mechanism of acupuncture in discopathies has not been fully elucidated, but its analgesic effects, anti-inflammatory and restoration of sensory and motor function are known, showing results as good as surgical therapy

Hipotireoidismo em cães: aspectos gerais

Hypothyroidism is a common endocrine disorder in dogs caused by insufficient production and secretion of thyroid hormones. Most affected dogs have primary hypothyroidism that results from lymphocytic thyroiditis, idiopathic thyroid atrophy, or more rarely, neoplastic destruction. Secondary hypothyroidism resulting from inadequate secretion of thyrotropin (thyroid-stimulating hormone –TSH) from the pituitary gland is less commonly recognized. Tertiary hypothyroidism resulting from a deficiency of hypothalamic thyrotropin-releasing hormone (TRH) has not been documented in dogs. The diagnosis of hypothyroidism in dogs is made on the basis of clinical findings, results of routine laboratory and thyroid gland function tests and response to thyroid hormone replacement. Unfortunately, these tests have high sensitivity, but low specificity, for use in the diagnosis of hypothyroidism. Thyroid hormone supplementation is indicated for the treatment of confirmed hypothyroidism and for the diagnoses of the disease through clinical response to trial therapy

Síndromes paraneoplásicas hematológicas em cães

Tumoral masses can cause several direct problems in the organism, such as invading organs and altering their functions, leading to other problems such as the Paraneoplastic syndrome. The paraneoplastic syndrome is an alteration in the structure and function of the body due to the non-invasive actions of the tumor, for example, liberating hormones, peptides, cytokines and leading to cross reactions between normal tissues. The syndrome can affect different locations in the body, being that some are indicative of specific tumors, however the interpretation of the clinical and pathological findings referring to this syndrome should be utilized in the diagnostic and treatment. In the hematological paraneoplastic syndrome, there are alterations that occur due to indirect actions of the tumor on the blood cellular elements and the coagulation system, and that are generally detected in routine clinical and laboratorial exams. This study objective is to aboard some hematological paraneoplastic syndromes in dogs such as: anemia, thrombocytopenia, neutrophilic leukocytosis, hypergammaglobulinemia and erythrocytosis, emphasizing the different etiologies that may assist in differential diagnosis and the principal neoplasm related to this syndrome. Besides this, the early discovery and treatment of the paraneoplatic syndrome is important as the tumor itself, as it improves the prognostic and quality of life of the patient

Hiperadrenocorticismo atípico em cães

The endocrine diseases, notably Cushing's disease, are of great importance from the morbid pictures that affect the canine species. Due to the imprecision of the standard tests, the HAC can be a diagnosis difficult to confirm. Often, the clinical manifestations and biochemical and hematological findings support the diagnosis of HAC, but endocrine tests are normal or inconclusive. The excessive production of ACTH may, in the adrenals, not only stimulate the increase of glucocorticoids, but also of sex hormones. In recent studies, the concentrations of sex hormones were used as parameters to check the adrenal gland function in animals with suspected Cushing's disease, suggesting that high serum concentrations of 17 hydroxyprogesterone (17OHP) and other sex steroid hormones would be the cause of the so called atypical hyperadrenocorticism

Insuficiência renal crônica em cães

The kidneys, for his anatomical and functional characteristics, are sensitive to affections that take the liberation of renal toxins or the blood supply, causing irreversible injuries to his renoparenchymal tissue that is substituted by fibrous tissue. Even after the resolution of the basic cause, there will be the loss of a significant number of his functional unity, renal adaptations will take place in the attempt of maintaining the renal function. These adaptations produce additional injuries, perpetuating to loss of renoparenchymal tissue and the reduction of the renal function. The renal insufficiency (IR) takes place after the loss of 3/4 of the number of his functional unities. Before the progression to the phase of IR, the animal shows up practically without symptoms, but for the gradual increase of the urinary and of the ingestion of water. The reduction of the degree of renal function leads to alterations system compensatory for the accumulation of substances that would suffer renal excretion. The progression of IR leads to the phase of the syndrome urêmica. In this phase the animal presents innumerable clinical signs that can take it to the death. The treatment is symptomatic and dietetic, but depending on the phase not much efficient. Because of being progressive and insidious, the IRC demands the preparation of campaigns and programs of explanation for the veterinary doctors who aim for the consciousness and/or sensibility of the owners to carry out periodic examinations of selection that precociously detect the renal dysfunction. The diagnosis in the beginning IR enables the efficiency of the treatment in stop or slowing his progression, extending the time and quality of life of the patient

Prostaglandina E2 em cães portadores de linfoma multicêntrico submetidos ao protocolo quimioterápico de Madison-Wisconsin associado ou não a um inibidor de COX-2

Pós-graduação em Medicina Veterinária - FCAV

Quantificação imunofenotípica de células T reguladoras em cães acometidos por linfoma multicêntrico submetidos ao protocolo quimioterápico chop associado ou não a um firocoxib

Pós-graduação em Medicina Veterinária - FCAV

Eletroforese das proteínas séricas e urinárias de cães com erliquiose subclínica

Pós-graduação em Medicina Veterinária - FCAV