O ensino de expressões idiomáticas à luz da lexicografia pedagógica

In the current context of lexicographical studies, there have been increasing discussions concerning the issue of the relationship between theoretical knowledge of the lexicon and pedagogical practices involved in its teaching. However, in this context, the special lexicon of Portuguese such as neologisms, foreign words, slang and idioms has received little attention from researchers. There are many theoretical studies on each one of these phenomena, but few studies aim at an organization and inclusion of special units in the teaching of Portuguese. For this reason, this article presents a reflection on the teaching of idioms, and, despite the widely held belief that dictionaries are only needed for the teaching of foreign languages, the article suggests the implementation of special dictionaries for the teaching of Portuguese Language in elementary education.

Territórios, gerações & cultura: (des)continuidades das expressões de gênero entre lésbicas

Our propose in this article is to articulate the ways how women that call themselves lesbians, live and consider the masculinities and the femininities. The discourses were obtained through semi-structured interviews with ten women from different ages, who live in different towns in São Paulo and Paraná states. Theoretical references were sought in poststruturalists authors who approach the social construction of gender and sexes as category analysis, necessary for the reflection of the subjectivity processes that are permeated by materiality and transitoriness that are inherent to social, historical, cultural, political and territorial contexts.

A tradução de expressões idiomáticas de baixa dedutibilidade metafórica: contribuições aos estudos fraseológicos bilíngues

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeitos do corticosteroide injetado no tendão calcâneo de coelhos: análise histológica, biomecânica e das expressões de metaloproteinases e interleucinas

Pós-graduação em Bases Gerais da Cirurgia - FMB

Efeitos do corticosteroide injetado no tendão calcâneo de coelhos: análise histológica, biomecânica e das expressões de metaloproteinases e interleucinas

Pós-graduação em Bases Gerais da Cirurgia - FMB

Endophytic Methylobacterium extorquens expresses a heterologous beta-1,4-endoglucanase A (EglA) in Catharanthus roseus seedlings, a model host plant for Xylella fastidiosa

Based on the premise of symbiotic control, we genetically modified the citrus endophytic bacterium Methylobacterium extorquens, strain AR1.6/2, and evaluated its capacity to colonize a model plant and its interaction with Xylella fastidiosa, the causative agent of Citrus Variegated Chlorosis (CVC). AR1.6/2 was genetically transformed to express heterologous GFP (Green Fluorescent Protein) and an endoglucanase A (EglA), generating the strains ARGFP and AREglA, respectively. By fluorescence microscopy, it was shown that ARGFP was able to colonize xylem vessels of the Catharanthus roseus seedlings. Using scanning electron microscopy, it was observed that AREglA and X. fastidiosa may co-inhabit the C. roseus vessels. M. extorquens was observed in the xylem with the phytopathogen X. fastidiosa, and appeared to cause a decrease in biofilm formation. AREglA stimulated the production of resistance protein, catalase, in the inoculated plants. This paper reports the successful transformation of AR1.6/2 to generate two different strains with a different gene each, and also indicates that AREglA and X. fastidiosa could interact inside the host plant, suggesting a possible strategy for the symbiotic control of CVC disease. Our results provide an enhanced understanding of the M. extorquens-X. fastidiosa interaction, suggesting the application of AR1.6/2 as an agent of symbiotic control.

Expressões utilizadas por familiares ao relatarem experiências de conviver com o adoecimento mental

OBJETIVO: Identificar as expressões usadas por familiares para descrever a experiência de conviver com o adoecimento mental. MÉTODOS: Tratase de pesquisa que realizou análise dos relatos de familiares por meio do software Analyse Lexicale par Contexte d'um Ensemble de Segments de Texte (ALCESTE), contendo metodologia de análise de dados qualitativos que se adapta a qualquer domínio de investigação, em que se pretenda tratar material textual. RESULTADOS: A análise realizada pelo ALCESTE forneceu quatro classes agrupadas duas a duas: Classe 2 -- início da doença e Classe 4 -- início do tratamento; Classe 1 -- convivência e Classe 3 - cotidiano. CONCLUSÃO: Os momentos descritos pelos familiares foram identificados por expressões, palavras e termos usados pelos mesmos em suas narrações. A principal contribuição deste estudo foi trazer a linguagem dos familiares para descrever os momentos do adoecimento por meio de uma metodologia de análise mais distante do pesquisador.

Estimulação do lado criativo nas crianças em educação pré-escolar nos domínios das expressões plástica e dramática

Relatório de estágio para a obtenção do grau de mestre em Educação pré-escolar

A proteção dos conhecimentos tradicionais e expressões de folclore / Patricia Pereira Tedeschi. --

Inclui bibliografia.

Human renal cell carcinoma expresses distinct binding sites for growth hormone-releasing hormone

Antagonists of growth hormone-releasing hormone (GHRH) inhibit the proliferation of various human cancers in vitro and in vivo by mechanisms that include apparent direct effects through specific binding sites expressed on tumors and that differ from pituitary human GHRH (hGHRH) receptors. In this study, GHRH antagonist JV-1–38 (20 μg/day per animal s.c.) inhibited the growth of orthotopic CAKI-1 human renal cell carcinoma (RCC) by 83% and inhibited the development of metastases to lung and lymph nodes. Using ligand competition assays with 125I-labeled GHRH antagonist JV-1–42, we demonstrated the presence of specific high-affinity (Kd = 0.25 ± 0.03 nM) binding sites for GHRH with a maximal binding capacity (Bmax) of 70.2 ± 4.1 fmol/mg of membrane protein in CAKI-1 tumors. These receptors bind GHRH antagonists preferentially and display a lower affinity for hGHRH. The binding of 125I-JV-1–42 is not inhibited by vasoactive intestinal peptide (VIP)-related peptides sharing structural homology with hGHRH. The receptors for GHRH antagonists on CAKI-1 tumors are distinct from binding sites detected with 125I-VIP (Kd = 0.89 ± 0.14 nM; Bmax = 183.5 ± 2.6 fmol/mg of protein) and also have different characteristics from GHRH receptors on rat pituitary as documented by the insignificant binding of [His1,125I-Tyr10,Nle27]hGHRH(1–32)NH2. Reverse transcription-PCR revealed the expression of splice variants of hGHRH receptor in CAKI-1 RCC. Biodistribution studies demonstrate an in vivo uptake of 125I-JV-1–42 by the RCC tumor tissue. The presence of specific receptor proteins that bind GHRH antagonists in CAKI-1 RCC supports the view that distinct binding sites that mediate the inhibitory effect of GHRH antagonists are present on various human cancers.