955 resultados para Exponential growth


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L’augmentation du nombre d’usagers de l’Internet a entraîné une croissance exponentielle dans les tables de routage. Cette taille prévoit l’atteinte d’un million de préfixes dans les prochaines années. De même, les routeurs au cœur de l’Internet peuvent facilement atteindre plusieurs centaines de connexions BGP simultanées avec des routeurs voisins. Dans une architecture classique des routeurs, le protocole BGP s’exécute comme une entité unique au sein du routeur. Cette architecture comporte deux inconvénients majeurs : l’extensibilité (scalabilité) et la fiabilité. D’un côté, la scalabilité de BGP est mesurable en termes de nombre de connexions et aussi par la taille maximale de la table de routage que l’interface de contrôle puisse supporter. De l’autre côté, la fiabilité est un sujet critique dans les routeurs au cœur de l’Internet. Si l’instance BGP s’arrête, toutes les connexions seront perdues et le nouvel état de la table de routage sera propagé tout au long de l’Internet dans un délai de convergence non trivial. Malgré la haute fiabilité des routeurs au cœur de l’Internet, leur résilience aux pannes est augmentée considérablement et celle-ci est implantée dans la majorité des cas via une redondance passive qui peut limiter la scalabilité du routeur. Dans cette thèse, on traite les deux inconvénients en proposant une nouvelle approche distribuée de BGP pour augmenter sa scalabilité ainsi que sa fiabilité sans changer la sémantique du protocole. L’architecture distribuée de BGP proposée dans la première contribution est faite pour satisfaire les deux contraintes : scalabilité et fiabilité. Ceci est accompli en exploitant adéquatement le parallélisme et la distribution des modules de BGP sur plusieurs cartes de contrôle. Dans cette contribution, les fonctionnalités de BGP sont divisées selon le paradigme « maître-esclave » et le RIB (Routing Information Base) est dupliqué sur plusieurs cartes de contrôle. Dans la deuxième contribution, on traite la tolérance aux pannes dans l’architecture élaborée dans la première contribution en proposant un mécanisme qui augmente la fiabilité. De plus, nous prouvons analytiquement dans cette contribution qu’en adoptant une telle architecture distribuée, la disponibilité de BGP sera augmentée considérablement versus une architecture monolithique. Dans la troisième contribution, on propose une méthode de partitionnement de la table de routage que nous avons appelé DRTP pour diviser la table de BGP sur plusieurs cartes de contrôle. Cette contribution vise à augmenter la scalabilité de la table de routage et la parallélisation de l’algorithme de recherche (Best Match Prefix) en partitionnant la table de routage sur plusieurs nœuds physiquement distribués.

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Introducción: Descripción de tendencias de indicadores seleccionados de Encuestas Nacionales de Demografía y Salud (ENDS) considerados de importancia para medición del alcance de los primeros 6 objetivos de desarrollo del milenio (ODM). Metodología: Estudio descriptivo retrospectivo, análisis de 18 indicadores de salud, por disponibilidad de datos de ENDS 1990 - 2010. Análisis con estadística descriptiva datos disponibles y modelo matemático de crecimiento exponencial para determinar proyección al 2015. Resultados: ODM1, quintil de riqueza “más bajo” en el 18.4% de la población y la proyección 2015 es 19.6%, la desnutrición global ha disminuido; ODM2, porcentaje de asistencia escolar ha incrementado (2010, 94%); ODM3, ocupación mujeres en agricultura ha disminuido en últimos 20 años (2010, 4,6%) y ha incrementado actividades de mayor preparación; se mantienen los diferentes tipos de violencia contra la mujer; ODM4, desde 1995 ha disminuido la mortalidad en la niñez y aumento de cobertura en vacunación desde 2000; ODM5, atención “profesional” del parto con incremento hasta 92.7% en 2010, incremento en conocimiento de métodos anticonceptivos; ODM6 mayor uso del condón y mayores conocimientos de métodos para evitar VIH. Discusión: Avances en los ODM 2, 3, 4 y 5, que van de la mano con estrategias planteadas para el cumplimiento de los ODM, con gran impacto en disminución de la desnutrición y de la mortalidad en menores de 5 años, mejoría en la atención pre/postnatal. Algunos objetivos según las tendencias no serán alcanzados como el ODM1 cuyo indicador muestra que el número de personas en situación de pobreza podría aumentar.

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Mobile internet represents a major new trend in communication technologies use and consumption, but few evidence exists that confirms claims of novelty and social change in association with this technology use. This paper characterizes the use of mobile internet in a southern European country and associated patterns of use, focusing both on users’ profiles, forms of access, motivations to use and most popular activities undertaken via this technology, from a diffusion of innovations and social adoption of technologies perspectives, and tries to compare mobile it with fixed access to the internet in order to validate possible transformations that point to new social configurations. We seek to understand the way stakeholders perceive and characterize the European context of mobile internet. The depicted study involved a qualitative stage consisting of a set of interviews with mobile communications industry representatives and market research community in the country. These interviews were analysed in Nvivo, leading to the following eleven main categories that are explored throughout the paper: smartphones in Europe, mobile internet in Europe, users profiles, obstacles to the spread, forms of access, forms of use, motivations to use mobile internet, limitations of smartphones, apps, digital divide VS digital union and predictions for the future, as well as several subcategories forming a tree categorization. According to the data collected, mobile phones’ sales are decreasing in Europe and worldwide but on the other hand smartphones are having an exponential growth which leads to the democratization of internet access via mobile devices. As a consequence of this, it is believed that mobile internet access will soon exceed the fixed one. Mobile internet users are multiplatform, they exploit all the possibilities of mobility and they are spending less time on computers. The main obstacles to the spread of mobile internet are the high prices of price plans and there is still a lack of information and knowledge regarding the service. Mobile internet users are developing new online surfing behaviours based on apps and less in browsers and social networks represent a very high share of internet traffic through mobile phones. With mobility, “dead time” is turning into useful time and users are more likely to be available to try new services and analyze products. Innovative services concerning geolocation, consumerism, share and relationships are growing and it is necessary to highlight that mobile internet allows calling and texting, which can turn telecommunications companies into the role of Dump Pipes. This exploratory design raises questions in relation with mobile internet access and its social consequences, and provides interesting indicative research results relevant for future research in this area.

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Vertically pointing Doppler radar has been used to study the evolution of ice particles as they sediment through a cirrus cloud. The measured Doppler fall speeds, together with radar-derived estimates for the altitude of cloud top, are used to estimate a characteristic fall time tc for the `average' ice particle. The change in radar reflectivity Z is studied as a function of tc, and is found to increase exponentially with fall time. We use the idea of dynamically scaling particle size distributions to show that this behaviour implies exponential growth of the average particle size, and argue that this exponential growth is a signature of ice crystal aggregation.

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An appropriate model of recent human evolution is not only important to understand our own history, but it is necessary to disentangle the effects of demography and selection on genome diversity. Although most genetic data support the view that our species originated recently in Africa, it is still unclear if it completely replaced former members of the Homo genus, or if some interbreeding occurred during its range expansion. Several scenarios of modern human evolution have been proposed on the basis of molecular and paleontological data, but their likelihood has never been statistically assessed. Using DNA data from 50 nuclear loci sequenced in African, Asian and Native American samples, we show here by extensive simulations that a simple African replacement model with exponential growth has a higher probability (78%) as compared with alternative multiregional evolution or assimilation scenarios. A Bayesian analysis of the data under this best supported model points to an origin of our species approximate to 141 thousand years ago (Kya), an exit out-of-Africa approximate to 51 Kya, and a recent colonization of the Americas approximate to 10.5 Kya. We also find that the African replacement model explains not only the shallow ancestry of mtDNA or Y-chromosomes but also the occurrence of deep lineages at some autosomal loci, which has been formerly interpreted as a sign of interbreeding with Homo erectus.

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The ability of Escherichia coli O157:H7 to colonize the intestinal epithelia is dependent on the expression of intimin and other adhesins. The chromosome of E. coli O157:H7 carries two loci encoding long polar fimbriae (LPF). These fimbriae mediate adherence to epithelial cells and are associated with colonization of the intestine. In order to increase our knowledge about the conditions controlling their expression and their role in colonization of an animal model, the environmental cues that promote expression of lpf genes and the role of E. coli O157:H7 LPF in intestinal colonization of lambs were investigated. We found that expression of lpf1 was regulated in response to growth phase, osmolarity, and pH; that lpf2 transcription was stimulated during late exponential growth and iron depletion; and that LPF impacts the ability of E. coli O157:H7 to persist in the intestine of infected 6-week-old lambs.

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The use of carbon nanotubes (CNTs) combined with other materials in nanostructured films has demonstrated their versatility in tailoring specific properties. In this study, we produced layer-by-layer (LbL) films of polyamidoamine-PAMAM-incorporating multiwalled carbon nanotubes (PAMAM-NT) alternated with nickel tetrasulfonated metallophthalocyanine (NiTsPc), in which the incorporation of CNTs enhanced the NiTsPc redox process and its electrocatalytic properties for detecting dopamine. Film growth was monitored by UV-vis spectroscopy, which pointed to an exponential growth of the multilayers, whose roughness increased with the number of bilayers according to atomic force microscopy (AFM) analysis. Strong interactions between -NH3+ terminal groups from PAMAM and -SO3- from NiTsPc were observed via infrared spectroscopy, while the micro-Raman spectra confirmed the adsorption of carbon nanotubes (CNTs) onto the LbL film containing NiTsPc. Cyclic voltammograms presented well-defined electroactivity with a redox pair at 0.86 and 0.87 V, reversibility, a charge-transfer controlled process, and high stability up to 100 cycles. The films were employed successfully in dopamine (DA) detection, with limits of detection and quantification of 10(-7) and 10(-6) mol L-1, respectively. Furthermore, films containing immobilized CNTs could distinguish between DA and its natural interferent, ascorbic acid (AA).

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This paper describes the development and application of an RP HPLC method using a C(18) monolithic stationary phase for the separation and quantification of extra- and intracellular amino acids in a batch cultivation of the marine alga Tetraselmis gracilis. Fluorimetric detection was made after separation of the o-phthaldialdehyde 2-mercaptoethanol (OPA-2MCE) derivatives using a binary gradient elution. Separation of 19 amino acids was achieved with resolution >1.5 in about 39 min at a flow rate of 1.5 mL/min. RSD of analyses in seawater medium ranged from 0.36% for Orn (0.50 mu mol/L) to 12% for Ile (0.10 mu mol/L). The main constituents of the intracellular dissolved free amino acids (DFAAs) in the exponential growth phase were arginine (Arg), asparagine (Asn), alanine (Ala), aspartic acid (Asp), glutamic acid (Glu), serine (Ser), glycine (Gly), glutamine (Gln), and leucine (Leu). The major amino acids excreted to the media were valine (Val), Ala, Ser, and Gly. The monolithic phase facilitates the analysis by shortening the separation time and saving solvents and instrumentation costs (indeed conventional HPLC instrumentation can be used, running at lower pressures than those ones used with packed particle columns).

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This research was as principal interest to verify the motives the prominence of crescent outstanding of distance education in brazilian higher education. To make real the study were used the bibliographical and field researches. The bibliographical informations permitted to conclude that the total success of distance education in Brazil strikes against two obstacles: the digital exclusion and illiteracy. These, in turn, have created another problem called today digital illiteracy. Although there are those limitations, by the data about distance education in the country, it is patent that this modality of education is gaining more and more space in brazilian educational process. It has to detach that the greatest concentration of distance courses accredited in Brazil occurs in higher education. Today, distance courses at this level in the country are authorized in sequential, graduation, specialization, master and doctorate areas. The field research led to confirm practically all suppositions about the increase of distance education in higher education, proposed in anticipation. The flexibility that makes possible the transmission of knowledge at any place and time and the new technologies, chiefly the Internet, were the factors that more impelled the increase of distance education in brazilian higher teaching. Meanwhile, the quality improving of the courses was the less significative in respect to the growth of distance education it the higher level in Brazil. But, this fact does not signify that the distance higher courses have not quality. On the contrary, the courses are ministered by professionals of confirmed competence. What can still legitimize the presence of quality in distance higher teaching is its exponential growth in the country. Moreover, the importance attributed to the pedagogical project well planned in distance higher courses demonstrates the interest by excellence in the distance learning. Certainly, when a pedagogical project is well delineated, at any level of distance teaching, the trend of quality is perfect itself.

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Desde à muito, os temas, capital social e comportamento de cidadania organizacional (CCO) têm sido extensivamente pesquisado e estudados nos EUA, no entanto estes têm recebido pouca relevância a nível de outros contextos internacionais. Se por um lado, a sua importância e inferência na performance dentro do contexto empresarial têm sido crescente, caracterizando a necessidade de um entendimento cada vez maior por parte das empresas, por outro, o investimento das corporações de grande porte, caminham cada vez mais em direção dos países com crescimento exponencial sustentado, como são o BRIC, o que cna uma necessidade fomentada de pesquisa nesta área de pesquisa para estas regiões. Este estudo pretendeu investigar, avaliar e mapear a influência do capital e do CCO na satisfação de vida e desempenho no trabalho do funcionário de nível superior, no contexto empresarial brasileiro e português, com o objetivo de identificar quais as diferenças existentes nestes duas realidade, devido ao investimento crescente do segundo para com o primeiro. Genericamente, encontramos clara influência das dimensões do CCO tanto para o desempenho no trabalho como para a satisfação de vida do trabalhador, assim como presença também marcada das duas dimensões do capital Social. Mais especificamente, foi entendido pelo nosso estudo que a realidade empresarial brasileira necessita que as empresas criem mecanismos que fomentem os laços entre colegas, a conscienciosidade, altruísmo e virtude cívica dos seus funcionários, pois assim aumentará o desempenho. Já para o contexto português, apenas a conscienciosidade e a virtude apresentaram significativa relação. Desta forma, conclui-se que para o investimento das empresas português no Brasil, estas precisam ter atenção à dimensão estrutural - relação com colegas - promovendo-a e à necessidade patente que os brasileiros têm de ajudar os seus colegas - comportamento altruísta - para aumentar o desempenho no trabalho. No que se refere a satisfação de vida, que se mostrou estreitamente relacionada com o desempenho, o brasileiro apenas precisa notar confiança nos colegas, senti-se altruísta e consciencioso, ao passo que o português necessita criar fortes laços com os colegas, mas não fomentar o comportamento altruístico. Desta forma as empresas investidoras apenas precisam ter atenção mais uma vez a necessidade de prestar ajuda especifica que o brasileiro sente, promovendo workshops com os próprios funcionários, por forma a estes passarem o seu conhecimento, monitorias, estágios, entre outros. Estes resultados demonstraram que cada continente, país (possuidor ou não da mesma língua) e/ou cultura comporta diferenças significativas no contexto empresarial, assim tornase difícil implementar técnicas e comportamentos internacionais e esperar que os resultados sejam exatamente iguais. Este estudo espera dar alguns instrumentos de comparação para que as empresas portuguesas entendam, a este nível, a realidade brasileira.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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A cytogenetic study was carried out with 5-azacytidine (5-azaC) and etoposide (VP-16) in CHO-K1 and XRS-5 (mutant cells deficient for double-strand break rejoining) cell lines to verify the interaction effects of the drugs in terms of induction of chromosomal aberrations. 5-azaC is incorporated into DNA causing DNA hypomethylation, and VP-16 (inhibitor of topoisomerase 11 enzyme) is a potent clastogenic agent. Cells in exponential growth were treated with 5-azaC for I h, following incubation for 7 h, and posttreatment with VP16 for the last 3 h. In K1 cells, the combined treatments induced a significant reduction in the aberrations induced in the X and A (autosome) chromosomes, which are the main target for 5-azaC. However, in XRS-5 cells, the drug combination caused a significant increase in the aberrations induced in those chromosomes, but with a concomitant reduction in the randomly induced-aberrations. In addition, each cell line presented characteristic cell cycle kinetics; while the combined treatment induced an S-arrest in K1 cells, alterations in cell cycle progression were not found for XRS-5, although each drug alone caused a G2-arrest. The different cell responses presented by the cell lines may be explained on the basis of the evidence that alterations in chromatin structure caused by 5-aza-C probably occur to a different extent in K1 and XRS-5 cells, since the mutant cells present a typical hyper-condensed chromosome structure (especially the X- and A chromosomes), but, alternatively, 5-aza-C could induce reactivation of DNA repair genes in XRS-5 cells. Teratogenesis Carcinog. Mutagen. Suppl. 1:171-186, 2003. (C) 2003 Wiley-Liss, Inc.

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Os métodos de incubação de solo fornecem subsídios técnicos para a avaliação da mineralização e disponibilidade de N. Nesse sentido, os objetivos deste trabalho foram avaliar a mineralização potencial e líquida do N orgânico em solos e relacioná-la à disponibilidade de N para plantas. Amostras de 22 solos coletadas na camada arável (0 a 20 cm) foram submetidas à incubação em condições aeróbias a 35 °C, por 30 semanas, e anaeróbias a 40 °C, por sete dias, e utilizadas em experimento, em casa de vegetação, em que o milho foi a planta-teste. Durante a incubação por 30 semanas, houve aumento do N mineralizado na segunda semana, seguido de diminuição e estabilização a partir da quarta semana. Este comportamento resultou em ajuste do N mineralizado (Nm) ao modelo exponencial de decrescimento e do N mineralizado acumulado (Nmac) ao modelo exponencial de crescimento, a partir do qual foi possível calcular o N potencialmente mineralizável (N0). As quantidades de N0 refletiram a mineralização e a disponibilidade de N em longo prazo. Contudo, o Nmac apresentou maior grau de correlação com o N disponível medido pelas plantas (concentração de N e N acumulado na parte aérea) do que o N0, e valores altos de correlação foram obtidos já após duas semanas de incubação, o que indica que a modelagem matemática pode ser dispensada e o período de incubação pode ser encurtado. O N total do solo foi melhor índice da mineralização potencial e líquida de N orgânico do que a matéria orgânica do solo, principalmente em longo prazo. O método de incubação anaeróbia de curta duração pode ser utilizado para cálculo da estimativa do N0, e a subtração do N-NH4+ inicial não contribuiu para melhorar a estimativa da mineralização e da disponibilidade de N por meio deste método, o que o torna ainda mais simples e viável.

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The exponential growth in the applications of radio frequency (RF) is accompanied by great challenges as more efficient use of spectrum as in the design of new architectures for multi-standard receivers or software defined radio (SDR) . The key challenge in designing architecture of the software defined radio is the implementation of a wide-band receiver, reconfigurable, low cost, low power consumption, higher level of integration and flexibility. As a new solution of SDR design, a direct demodulator architecture, based on fiveport technology, or multi-port demodulator, has been proposed. However, the use of the five-port as a direct-conversion receiver requires an I/Q calibration (or regeneration) procedure in order to generate the in-phase (I) and quadrature (Q) components of the transmitted baseband signal. In this work, we propose to evaluate the performance of a blind calibration technique without additional knowledge about training or pilot sequences of the transmitted signal based on independent component analysis for the regeneration of I/Q five-port downconversion, by exploiting the information on the statistical properties of the three output signals

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Nanostructured materials have been spreading successfully over past years due its size and unusual properties, resulting in an exponential growth of research activities devoted to nanoscience and nanotechnology, which has stimulated the search for different methods to control main properties of nanomaterials and make them suitable for applications with high added value. In the late 90 s an alternative and low cost method was proposed from alkaline hydrothermal synthesis of nanotubes. Based on this context, the objective of this work was to prepare different materials based on TiO2 anatase using hydrothermal synthesis method proposed by Kasuga and submit them to an acid wash treatment, in order to check the structural behavior of final samples. They were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), adsorption/desorption of N2, thermal analysis (TG/DTA) and various spectroscopic methods such as absorption spectroscopy in the infrared (FT-IR), Raman spectroscopy and X-ray photoelectron spectroscopy (XPS). All the information of characterizations confirmed the complete conversion of anatase TiO2 in nanotubes titanates (TTNT). Observing the influence of acid washing treatment in titanates structure, it was concluded that the nanotubes are formed during heat treatment, the sample which was not subjected to this process also achieved a complete phase transformation, as showed in crystallography and morphology results, however the surface area of them practically doubled after the acid washing. By spectroscopy was performed a discussion about chemical composition of these titanates, obtaining relevant results. Finally, it was observed that the products obtained in this work are potential materials for various applications in adsorption, catalysis and photocatalysis, showing great promise in CO2 capture