The Spanish empire in America : containing, a succinct relation of the discovery and settlement of its several colonies; a view of their respective situations, extent, commodities, trade, &c. : and a full and clear account of the commerce with Old Spain by the galleons, flota, &c. ; also of the contraband trade with the English, Dutch, French, Danes and Portuguese, with an exact description of Paraguay /

Memoir concerning the settlements of the Jesuits in Paraguay, by a French officer: p. 321-330.

History of Texas, from its discovery and settlement, with a description of its principal cities and counties, and the agricultural, mineral, and material resources of the state.

Mode of access: Internet.

The history of the discovery and settlement of America.

Mode of access: Internet.

Hours with the Bible; or, The scriptures in the light of modern discovery and knowledge.

Mode of access: Internet.

The new Werner twentieth century edition of the Encyclopaedia Britannica a standard work of reference in art, literature, science, history, geography, commerce, biography, discovery and invention.

Vol. 30: Index.

Hours with the Bible: or, The Scriptures in the light of modern discovery and knowledge,

v.1. From creation to the patriarchs.--v.2. From Moses to the judges.--v.3. From Samson to Solomon.--v.4. Rehoboam to Hezekiah.--v.5. From Menasseth to Zedekia and contemporary prophets.--v.6. From the exile to Malachi.

Hours with the Bible : or, The Scriptures in the light of modern discovery and knowledge ... /

Mode of access: Internet.

History of redemption : on a plan entirely original, exhibiting the gradual discovery and accomplishment of the divine purposes in the salvation of man ; including a comprehensive view of church history, and the fulfilment of scripture prophecies ; with The life and experience of the author /

Mode of access: Internet.

The history of the first discovery and settlement of Virginia;

"Reprint edition ... [includes] index prepared in 1912 by Morgan Poitiaux Robinson for the Virginia State Library."

History of the discovery and conquest of Costa Rica /

Includes bibliographical references and index.

History of the discovery and settlement of the valley of the Mississippi, by the three great European powers, Spain, France, and Great Britain, and the subsequent occupation, settlement, and extension of civil government by the United States until the year 1846 /

References: Howes, U.S.IANA, no. M.722.

A history of Virginia : from its discovery and settlement by Europeans to the present time /

Imprint of v. 2: Richmond : Drinker and Morris, 1848.

The chronicle of the discovery and conquest of Guinea /

Mode of access: Internet.

Price discovery and volatility spillovers in index futures markets: Some evidence from Mexico

This paper investigates the hypotheses that the recently established Mexican stock index futures market effectively serves the price discovery function, and that the introduction of futures trading has provoked volatility in the underlying spot market. We test both hypotheses simultaneously with daily data from Mexico in the context of a modified EGARCH model that also incorporates possible cointegration between the futures and spot markets. The evidence supports both hypotheses, suggesting that the futures market in Mexico is a useful price discovery vehicle, although futures trading has also been a source of instability for the spot market. Several managerial implications are derived and discussed. (C) 2004 Elsevier B.V. All rights reserved.

Discovery and characterization of a linear cyclotide from Viola odorata: Implications for the processing of circular proteins

Cyclotides are mini-proteins of 28-37 amino acid residues that have the unusual feature of a head-to-tail cyclic backbone surrounding a cystine knot. This molecular architecture gives the cyclotides heightened resistance to thermal, chemical and enzymatic degradation and has prompted investigations into their use as scaffolds in peptide therapeutics. There are now more than 80 reported cyclotide sequences from plants in the families Rubiaceae, Violaceae and Cucurbitaceae, with a wide variety of biological activities observed. However, potentially limiting the development of cyclotide-based therapeutics is a lack of understanding of the mechanism by which these peptides are cyclized in vivo. Until now, no linear versions of cyclotides have been reported, limiting our understanding of the cyclization mechanism. This study reports the discovery of a naturally occurring linear cyclotide, violacin A, from the plant Viola odorata and discusses the implications for in vivo cyclization of peptides. The elucidation of the cDNA clone of violacin A revealed a point mutation that introduces a stop codon, which inhibits the translation of a key Asn residue that is thought to be required for cyclization. The three-dimensional solution structure of violacin A was determined and found to adopt the cystine knot fold of native cyclotides. Enzymatic stability assays on violacin A indicate that despite an increase in the flexibility of the structure relative to cyclic counterparts, the cystine knot preserves the overall stability of the molecule. (c) 2006 Elsevier Ltd. All rights reserved.