970 resultados para DISPERSE-RED-1
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Talamanca de Jarama posee un rico patrimonio arquitectónico que se ha ido degradando con el paso del tiempo. Aunque se han considerado realizar acciones para remediar esta situación pocas han sido acometidas, debido a la magnitud que requieren y los recursos insuficientes propios de la localidad. En este sentido, muchos municipios de España no pueden realizar ni acometer, por sí mismos, trabajos que superan su capacidad económica y dependen de las administraciones autonómicas o estatales, que realizan los trámites pertinentes para otorgar la financiación o la subvención conveniente, en caso de fallar a favor del proyecto en cuestión. Actualmente, en la Ley de Patrimonio Histórico, existe el denominado 1% Cultural, que “establece la obligación de destinar en los contratos de obras públicas una partida de, al menos, el 1% a trabajos de conservación o enriquecimiento del Patrimonio Histórico Español”. En esta línea, desde la Dirección General de Patrimonio Histórico, de la Comunidad de Madrid, se están llevando a cabo los trámites y trabajos necesarios para restaurar parte del recinto fortificado de Talamanca de Jarama, percatándose de la falta de cartografía y documentación gráfica actualizada del mismo, que apoye esas labores y las que pudieran presentarse en el futuro, llevándose a cabo, en 2011, un “proyecto de ejecución para la restauración de la puerta de la Tostonera y de un tramo del sector oriental del recinto fortificado de Talamanca de Jarama”, en el que se realiza un estudio y propuesta de intervención detallados sobre la muralla, figurando la totalidad del mismo en el Anexo IV. Advirtiendo esta carencia, el presente proyecto pretende dar soporte cartográfico a los trabajos que tengan por objeto dicho monumento y facilitar la información a las distintas Administraciones Públicas, para que éstas, a su vez, dispongan y divulguen su contenido a las personas o entes que lo requieran. A tenor de los antecedentes expuestos anteriormente, el presente proyecto tiene por objetivos: - Implantación de una red básica enlazada con la Red Geodésica Nacional por Técnicas Espaciales (REGENTE) y apoyada en vértices ROI, mediante técnicas GPS y topografía clásica, que dé cobertura a todo el perímetro amurallado, con una extensión de 10 Ha. - Realización de un levantamiento topográfico a escala 1:500, de 10 Ha, de la muralla intramuros y extramuros. - Realización de la cartografía a escala 1:500.
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The X chromosome-linked transcription factor GATA-1 is expressed specifically in erythroid, mast, megakaryocyte, and eosinophil lineages, as well as in hematopoietic progenitors. Prior studies revealed that gene-disrupted GATA-1- embryonic stem cells give rise to adult (or definitive) erythroid precursors arrested at the proerythroblast stage in vitro and fail to contribute to adult red blood cells in chimeric mice but did not clarify a role in embryonic (or yolk sac derived) erythroid cells. To examine the consequences of GATA-1 loss on embryonic erythropoiesis in vivo, we inactivated the GATA-1 locus in embryonic stem cells by gene targeting and transmitted the mutated allele through the mouse germ line. Male GATA-1- embryos die between embryonic day 10.5 and 11.5 (E10.5-E11.5) of gestation. At E9.5, GATA-1- embryos exhibit extreme pallor yet contain embryonic erythroid cells arrested at an early proerythroblast-like stage of their development. Embryos stain weakly with benzidine reagent, and yolk sac cells express globin RNAs, indicating globin gene activation in the absence of GATA-1. Female heterozygotes (GATA-1+/-) are born pale due to random inactivation of the X chromosome bearing the normal allele. However, these mice recover during the neonatal period, presumably as a result of in vivo selection for progenitors able to express GATA-1. Our findings conclusively establish the essential role for GATA-1 in erythropoiesis within the context of the intact developing mouse and further demonstrate that the block to cellular maturation is similar in GATA-1- embryonic and definitive erythroid precursors. Moreover, the recovery of GATA-1+/- mice from anemia seen at birth provides evidence indicating a role for GATA-1 at the hematopoietic progenitor cell level.
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We have studied the main evolutionary paths among the galaxy types residing on the massive end of the Red Sequence and nearby locations on the Green Valley during the last ∼9 Gyr. The morphological and star formation properties of a sample of these galaxies at 0 . 3 < z < 1 .5 with stellar masses M_∗ > 5 × 10^10 M_⊙ have been analysed. We present direct observational evidence for the first time of the existence of two main evolutionary paths among the different red galaxy types since z ∼ 1 .5, which provide some clues on the nature of the processes that have governed the assembly of present-day massive quiescent galaxies. The results are in excellent agreement with the hierarchical evolutionary framework proposed in the Eliche-Moral et al. (2010) model. Data from SHARDS (one of the ESO/GTC Large Programmes approved in 2009A) will complement and improve the present findings, shedding some light into many of the still unsettled questions concerning the migration of galaxies from the Blue Cloud to the Red Sequence at z < 1 .5.
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Chloroform extracts of water-soluble organic matter collected in the water column from the surface to the bottom were studied by C-13 and H-1 NMR chromatographic mass spectrometry, and phthalate concentrations were determined by capillary gas-liquid chromatography. More than 14 compounds were found including diethyl phthalate, ethyl butyl phthalate, dibutyl phthalate, and di-2-ethylhexyl phthalate, phthalates with normal C4-C12 chains, phthalates partially esterified with methanol, and others, at total concentrations up to 0.4 mg/l. Possible reasons for presence of phthalates in oceans, sometimes in high concentrations, are discussed.
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The study of textural, structural, chemical, and physical properties of fine-grained recent marine sediments leads to the conclusion that only a few compositional factors are responsible for significant changes in mass physical characteristics in the upper meters below sea bottom. Fossil-induced porosity increases water content and liquid limit. It also seems to have partially influenced the plastic limit and plasticity index of calcareous sandy silts from the Red Sea and the western Gulf of Aden so that they become similar to the montmorillonite rich prodelta clays from the Nile Delta. Diagrams based on liquid limit and plasticity loose their original meaning in these cases. Activity of sediments rich in microorganisms can be higher than that of montmorillonitic clay. The shear strength-depth relationship of normally consolidated sediments is surprisingly little influenced by changes in sand or clay content and clay mineralogy. Only high lime content, submarine erosion and beginning cementation increase the strength considerably. Erosional disconformities near the present surface can be deduced from the strength-depth curve when as little as 1 or 2 m sediment have been removed. Flat or irregular strength-depth curves indicate beginning cementation and probably discontinuous sedimentation, provided the composition of the material remains in some degree constant. In our samples diagenetic pyrite, but no recristallisation of carbonates could be detected under the microscope. Underconsolidation and excess pore-water pressure, factors which tend to foster submarine slides, mud lumps, and diapiric folding, seem to be restricted Varito areas with mainly rapidly deposited, homogeneous or layered sediments. But where an abundance of burrowing organisms increases the vertical permeability of the sediment, normal consolidation and stable deposits are to be expected, at least in the upper meters below the present surface. According to 14C-determinations on calcareous microorganisms the rate of deposition of the investigated sediments seems to range from 26 to 167 cm per 1000 years.
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The stratigraphic position of the glacially transported 'Scholle' (large-size erratic block) at Schobüll near Husum (Schleswig-Holstein) is now considered to be Devonian rather than 'Rotliegendes'. The 'Scholle', consisting of red clay and dolomite, is overlain by red-colored till without any flint but with up to 90% carbonate clasts (containing 15% dolomite), which indicates an eastern Baltic origin. The relationship of the 'Scholle' with the glacial till also points to an eastern Baltic origin for it, with up to 1 000 km transport distance.
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New results of geothermal studies at 18°N in the Red Sea rift zone are discussed. It was established that the thermal field of the African plate in this area has a higher than ordinary level, and averages 3.0-3.5 UTF. Heat flow of the Arabian plate is characterized by negative anomalies and is local in character in comparison to adjoining areas of the rift.
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verso: parade? Church is in the 100 block (-L. Steck)
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We have determined the crystal structure of HcRed, a far-red fluorescent protein isolated from Heteractis crispa, to 2.1 resolution. HcRed was observed to form a dimer, in contrast to the monomeric form of green fluorescent protein (GFP) or the tetrameric forms of the GFP-like proteins (eqFP611, Rtms5 and DsRed). Unlike the well-defined chromophore conformation observed in GFP and the GFP-like proteins, the HcRed chromophore was observed to be considerably mobile. Within the HcRed structure, the cyclic tripeptide chromophore, Glu64-Tyr65-Gly66, was observed to adopt both a cis coplanar and a tran. non-coplanar conformation. As a result of these two con formations, the hydroxyphenyl moiety of the chromophore makes distinct interactions within the interior of the b-can. These data together with a quantum chemical model of the chromophore, suggest the cis coplanar conformation to be consistent with the fluorescent properties of HcRed, and the trans non-coplanar conformation to be consistent with non-fluorescent properties of hcCP, the chromoprotein parent of HcRed. Moreover, within the GFP-like family, it appears that where conformational freedom is permissible then flexibility in the chromophore conformation is possible. 2005 Elsevier Ltd. All rights reserved.