The letters of Charles Lamb, in which many mutilated words and passages have been restored to their original form: with letters never before published and facsimiles of original ms. letters and poems;

"Notes on facsimile letters of Charles Lamb by Dr. Richard Garnett."

Poems by Robert Louis Stevenson,

"This edition is limited to 484 copies."

Annual Report

Mode of access: Internet.

Publications

Volumes not numbered by the society

Report

Annual

The personal letters of John Fiske;

Introduction by H. H. Harper.

Letters and poems of Queen Elisabeth (Carmen Sylva)

"Poems ('Vers libre') by Carmen Sylva": vol. II, p. 175-222.

The journals of Washington Irving (hitherto unpublished)

This edition is limited to 430 copies printed for members only.

Obesity associated severe asthma represents a distinct clinical phenotype - Analysis of the British Thoracic Society Difficult Asthma Registry patient cohort according to body mass index

BACKGROUND: Obesity has emerged as a risk factor for the development of asthma and it may also influence asthma control and airways inflammation. However, the role of obesity in severe asthma remains unclear. OBJECTIVE: To explore the association between obesity (defined by BMI) and severe asthma. METHODS: Data from the National Registry for dedicated UK Difficult Asthma Services were used to compare patient demographics, disease characteristics and healthcare utilisation between three body mass index (BMI) categories (normal weight: 18.5 -24.99, overweight: 25 -29.99, obese: =30) in a well characterised group of severe asthmatic adults. RESULTS: The study population consisted of 666 severe asthmatics with a median BMI of 29.8 (interquartile range 22.5 -34.0). The obese group exhibited greater asthma medication requirements in terms of maintenance corticosteroid therapy (48.9% versus 40.4% and 34.5% in the overweight and normal weight groups, respectively), steroid burst therapy and short-acting ß2-agonist (SABA) use per day. Significant differences were seen with gastro-oesophageal reflux disease (GORD) (53.9% versus 48.1% and 39.7% in the overweight and normal weight groups, respectively) and proton pump inhibitor (PPI) use. Bone density scores were higher in the obese group, whilst pulmonary function testing revealed a reduced FVC and raised Kco. Serum IgE levels decreased with increasing BMI and the obese group were more likely to report eczema, but less likely to have a history of nasal polyps. CONCLUSIONS: Severe asthmatics display particular characteristics according to BMI that support the view that obesity associated severe asthma may represent a distinct clinical phenotype.1Royal Brompton Hospital, London, UK;2Department of Computing, Imperial College, UK3Airways Disease, National Heart & Lung Institute, Imperial College, UK;4Centre for infection and immunity, Queen's University of Belfast, UK;5University of Leicester, UK;6The University of Manchester and University Hospital of South Manchester, UK;7Birmingham Heartlands Hospital, University of Birmingham, UK;8Gartnavel General Hospital, University of Glasgow, UK;9Glasgow Royal Infirmary, Glasgow, UKCorrespondence: Dr Andrew N. Menzies-Gow, Royal Brompton Hospital, Fulham Road, London SW3 6HP.

The new mass media; challenge to a free society.

Includes bibliography.

Mass, class, and bureaucracy; the evolution of contemporary society

Includes bibliography.

Catalogue of the private library of Thomas Dowse, of Cambridge, Mass., presented to the Massachusetts historical society, July 30, 1856.

Mode of access: Internet.

A sermon, delivered before the Palestine Missionary Society, at their 31st annual meeting, held at Randolph, Mass., June 18, 1851.

Mode of access: Internet.

Catalogue of books belonging to the Library of the Porter Rhetorical Society, Theological Seminary, Andover, Mass. : April, 1839.

Mode of access: Internet.