114 resultados para Britt, Wayman


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Three MADS-box genes isolated from Monterey pine (Pinus radiata), PrMADS1, PrMADS2, and PrMADS3, are orthologs to members of the AGL2 and AGL6 gene subfamilies in Arabidopsis. These genes were expressed during early stages of pine shoot development in differentiating seed- and pollen-cone buds. Their transcripts were found within a group of cells that formed ovuliferous scale and microsporophyll primordia. Expression of PrMADS3 was also detected in a group of cells giving rise to needle primordia within differentiated vegetative buds, and in needle primordia.

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Electron spin echo electron-nuclear double resonance (ESE-ENDOR) experiments performed on a broad radical electron paramagnetic resonance (EPR) signal observed in photosystem II particles depleted of Ca2+ indicate that this signal arises from the redox-active tyrosine YZ. The tyrosine EPR signal width is increased relative to that observed in a manganese-depleted preparation due to a magnetic interaction between the photosystem II manganese cluster and the tyrosine radical. The manganese cluster is located asymmetrically with respect to the symmetry-related tyrosines YZ and YD. The distance between the YZ tyrosine and the manganese cluster is estimated to be approximately 4.5 A. Due to this close proximity of the Mn cluster and the redox-active tyrosine YZ, we propose that this tyrosine abstracts protons from substrate water bound to the Mn cluster.

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Mode of access: Internet.

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"Issued January 1965."

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Mode of access: Internet.

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Top Row: Kathleen S. Allen, Elizabeth Anderson, Mary Assenmacher, Deana Barrett, Laurie Barringer, Linda Baty, Holidae Bauman, Leila Beach, Liesha Beachum, Jacquline S. Bean, Jane Betten, Melanie Black, Kari Blouin, Kelly Bottger, Nancy Bowman, JoAnn Britenfeld, Ruth C. Brower

Row 2: Melanie Mai Brown, Estera Carp, Christine Haveman, Kimberly Webster, Rebecca Amo, Tina K. Ciricola, Gerard A. Castaneda, Steven J. Bednarski, Michelle Kuo, Kathleen Szymanski, Alissa Enriquez, Kristin Snow, Jennifer Berk, Erica Reese, Angela Cassadime, Lynn Chacko

Row 3: Anne chambers, Mechele Chau, Marcy Christensen, Regi Colthorp, Kellie Conover, Jenny Cwiek, Michele DeMaagd, Kristin Diotte, Amanda Dressel, Kimberly Dunlap, Esther DuRussel, Katrina Ehr

Row 4: Holly M. Greenough, Eileen Gumayagay, Sheila Habib, Allison Hale, Kristi Hale, Amy Hollis, Rebecca Hostman, Marilynn Huizinga, Jennifer Ivinson, Christine Jodoin, Christine Kaetz, Kimberly Kenny-Sherlock, Andrea Latva, Kathleen Levin

Row 5: Shawna Mangan, Sofia Marquez, Paul Mazurek, Charla McMichael, Tina Marie Meeks, Richard W. Redman, Beverly Jones, Ada Sue Hinshaw, Susan Boehm, Nola Pender, Jeffrey Mendoza, Melissa Meulenberg, Cheryl Milekovich, Amanda Miller, Amy Miller

Row 6: Nicole Miller, Bonnie Mobley, Kara More, Cherylann Mortzfield, Leslie Nance, Ruby Nzoma, Megan Oleszek, Larah Faye Ostonal, Jean C. Palad, Danielle Pankowski, Nancy Penrose, Laurie Pierce, Heather Polsen, Julie Marie Postma, Amy Prielipp, Martha Quigley, Aimee Racette

Row 7: Marty Rauser, Nekia Robinson, Kimberly Rowe, Janice Rybski, Ricardo Salazar, Marie Sanderson, Kimberly Scholma, Bonnie Schweitzer, Veena Shewakramani, Julie Showers, Olga Simanovskaya, Emily Simon, Lakeeta Smith, Amy Stewart, Robert Strudgeon, Jaime Sulek

Row 8: Charity Sutherland, William Ten Haaf, Mark Thomas, Nichole Thomas, Donna Thompson, Tonya Tomski, Michele Uller, Celina Uranga, Sarah Volkhardt, Larna Welch, Melanie White, Michelle White, Britt Williams, Stephanie Windisch, Brian Wright, Christina Wyrybkowski, Lisa Ziegelmann

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"February 1997."

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Thesis (Master's)--University of Washington, 2016-06

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The heterogeneous nuclear ribonucleoprotein (hnRNP) A2 is a multi-tasking protein that acts in the cytoplasm and nucleus. We have explored the possibility that this protein is associated with telomeres and participates in their maintenance. Rat brain hnRNP A2 was shown to have two nucleic acid binding sites. In the presence of heparin one site binds single-stranded oligodeoxyribonucleotides irrespective of sequence but not the corresponding oligoribonucleotides. Both the hnRNP A2-binding cis-acting element for the cytoplasmic RNA trafficking element, A2RE, and the ssDNA telomere repeat match a consensus sequence for binding to a second sequence-specific site identified by mutational analysis. hnRNP A2 protected the telomeric repeat sequence, but not the complementary sequence, against DNase digestion: the glycine-rich domain was found to be necessary, but not sufficient, for protection. The N-terminal RRM (RNA recognition motif) and tandem RRMs of hnRNP A2 also bind the single-stranded, template-containing segment of telomerase RNA. hnRNP A2 colocalizes with telomeric chromatin in the subset of PML bodies that are a hallmark of ALT cells, reinforcing the evidence for hnRNPs having a role in telomere maintenance. Our results support a model in which hnRNP A2 acts as a molecular adapter between single-stranded telomeric repeats, or telomerase RNA, and another segment of ssDNA.

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This paper seeks to report on smoking rates, quit attempt methods and success rates among adult patients attending Australian general practice. A cluster cross-sectional survey was used to survey adult patients (18+), who attended Australian GPs in during 2002 and 2003. Over a quarter of patients (27.3%; 95% CI: 26.0-28.7) were former smokers and one in five (21.5%; 95% CI: 20.1-22.9) were current smokers. Ninety-two percent of former and 80% of current smokers used only one method in their last quit attempt with cold turkey the most common method used by both former (88%) and current (62%) smokers. Overall, success rates varied from 77% for cold turkey to 23% for bupropion. Success rates were re-analysed to consider quit attempts post-bupropion listing, with success rate for cold turkey reduced to 40% while bupropion remained reasonably constant at 21%. By tailoring smoking cessation interventions to a smokers' preparedness to quit, scope exists to increase the pool of smokers offered strategies that are more effective in achieving abstinence and avoiding relapse rather than relying on less effective self-quitting behaviours such as cold turkey. (c) 2005 Elsevier Ltd. All rights reserved.

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More information on the biochemical interactions taking place between the tear film and the contact lens is required to further our understanding of the causative mechanisms behind the symptoms of dryness and grittiness often experienced by contact lens wearers. These symptoms can often lead to an intolerance to contact lens wear.

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Many factors can be, and have been, attributed to the appearance of complications in lens wear, but the greatest is associated with deposition. Reduced acuity, irritation and inflammatory responses are often referred to as adverse reactions arising as a result of deposition. In this study, particular attention was paid to the potential role of adsorbed proteins in activating, mediating and/or stimulating a host immune response, i.e., the hypothesis that the adsorption of certain proteins from the tears and ocular surfaces may actively affect successful lens wear. In particular, the purpose of this study was to investigate the presence of a group of proteins previously undiscovered in the ocular environment. The intention was to target a family of proteins/glycoproteins that have become prominent recently in a variety of inflammatory responses and disorders at many other mucosal associated sites around the body, e.g. in nasal rhinitis and in joint inflammation. The protein cascade in question is the kinin family of inflammatory mediators. The aim was to investigate their presence in the ocular environment, specifically in relation to contact lens wear, and consequently assess the implications of their discovery. High molecular weight kininogen (HMWK), with its central role in kinin responses, was investigated initially as the marker of kinin activity, with subsequent members examined thereafter.