Personal health data - Privacy policy harmonization and global enforcement

This workshop is jointly organized by EFMI Working Groups Security, Safety and Ethics and Personal Portable Devices in cooperation with IMIA Working Group "Security in Health Information Systems". In contemporary healthcare and personal health management the collection and use of personal health information takes place in different contexts and jurisdictions. Global use of health data is also expanding. The approach taken by different experts, health service providers, data subjects and secondary users in understanding privacy and the privacy expectations others may have is strongly context dependent. To make eHealth, global healthcare, mHealth and personal health management successful and to enable fair secondary use of personal health data, it is necessary to find a practical and functional balance between privacy expectations of stakeholder groups. The workshop will highlight these privacy concerns by presenting different cases and approaches. Workshop participants will analyse stakeholder privacy expectations that take place in different real-life contexts such as portable health devices and personal health records, and develop a mechanism to balance them in such a way that global protection of health data and its meaningful use is realized simultaneously. Based on the results of the workshop, initial requirements for a global healthcare information certification framework will be developed.

Probabilistic Inductive Querying Using ProbLog

We study how probabilistic reasoning and inductive querying can be combined within ProbLog, a recent probabilistic extension of Prolog. ProbLog can be regarded as a database system that supports both probabilistic and inductive reasoning through a variety of querying mechanisms. After a short introduction to ProbLog, we provide a survey of the different types of inductive queries that ProbLog supports, and show how it can be applied to the mining of large biological networks.

Segmenting point-sampled surfaces

Extracting features from point-based representations of geometric surface models is becoming increasingly important for purposes such as model classification, matching, and exploration. In an earlier paper, we proposed a multiphase segmentation process to identify elongated features in point-sampled surface models without the explicit construction of a mesh or other surface representation. The preliminary results demonstrated the strength and potential of the segmentation process, but the resulting segmentations were still of low quality, and the segmentation process could be slow. In this paper, we describe several algorithmic improvements to overcome the shortcomings of the segmentation process. To demonstrate the improved quality of the segmentation and the superior time efficiency of the new segmentation process, we present segmentation results obtained for various point-sampled surface models. We also discuss an application of our segmentation process to extract ridge-separated features in point-sampled surfaces of CAD models.

Studies towards synthesis, evolution and alignment characteristics of dense, millimeter long multiwalled carbon nanotube arrays

We report the synthesis of aligned arrays of millimeter long carbon nanotubes (CNTs), from benzene and ferrocene as the molecular precursor and catalyst respectively, by a one-step chemical vapor deposition technique. The length of the grown CNTs depends on the reaction temperature and increases from similar to 85 mu m to similar to 1.4 mm when the synthesis temperature is raised from 650 to 1100 degrees C, while the tube diameter is almost independent of the preparation temperature and is similar to 80 nm. The parallel arrangement of the CNTs, as well as their tube diameter can be verified spectroscopically by small angle X-ray scattering (SAXS) studies. Based on electron diffraction scattering (EDS) studies of the top and the base of the CNT films, a root growth process can be deduced.

Gap-Dependent Quasiparticle Dynamics and Coherent Acoustic Phonons in CaFe2As2 across Spin Density Wave Phase Transition

We report ultrafast quasiparticle (QP) dynamics and coherent acoustic phonons in undoped CaFe2As2 iron pnictide single crystals exhibiting spin-density wave (SDW) and concurrent structural phase transition at temperature T-SDW similar to 165K using femtosecond time-resolved pump-probe spectroscopy. The contributions in transient differential reflectivity arising from exponentially decaying QP relaxation and oscillatory coherent acoustic phonon mode show large variations in the vicinity of T-SDW. From the temperature-dependence of the QP recombination dynamics in the SDW phase, we evaluate a BCS-like temperature dependent charge gap with its zero-temperature value of similar to(1.6 perpendicular to 0.2)k(B)T(SDW), whereas, much above T-SDW, an electron-phonon coupling constant of similar to 0.13 has been estimated from the linear temperature-dependence of the QP relaxation time. The long-wavelength coherent acoustic phonons with typical time-period of similar to 100 ps have been analyzed in the light of propagating strain pulse model providing important results for the optical constants, sounds velocity and the elastic modulus of the crystal in the whole temperature range of 3 to 300 K.

Electronic band Structure and Photoemission Spectra of Graphene on Silicon Substrate

Synergizing graphene on silicon based nanostructures is pivotal in advancing nano-electronic device technology. A combination of molecular dynamics and density functional theory has been used to predict the electronic energy band structure and photo-emission spectrum for graphene-Si system with silicon as a substrate for graphene. The equilibrium geometry of the system after energy minimization is obtained from molecular dynamics simulations. For the stable geometry obtained, density functional theory calculations are employed to determine the energy band structure and dielectric constant of the system. Further the work function of the system which is a direct consequence of photoemission spectrum is calculated from the energy band structure using random phase approximations.

Systematic Analysis of Mycobacterial Acylation Reveals First Example of Acylation-mediated Regulation of Enzyme Activity of a Bacterial Phosphatase

Protein lysine acetylation is known to regulate multiple aspects of bacterial metabolism. However, its presence in mycobacterial signal transduction and virulence-associated proteins has not been studied. In this study, analysis of mycobacterial proteins from different cellular fractions indicated dynamic and widespread occurrence of lysine acetylation. Mycobacterium tuberculosis proteins regulating diverse physiological processes were then selected and expressed in the surrogate host Mycobacterium smegmatis. The purified proteins were analyzed for the presence of lysine acetylation, leading to the identification of 24 acetylated proteins. In addition, novel lysine succinylation and propionylation events were found to co-occur with acetylation on several proteins. Protein-tyrosine phosphatase B (PtpB), a secretory phosphatase that regulates phosphorylation of host proteins and plays a critical role in Mycobacterium infection, is modified by acetylation and succinylation at Lys-224. This residue is situated in a lid region that covers the enzyme's active site. Consequently, acetylation and succinylation negatively regulate the activity of PtpB.

Verringerung der Dorschbeifänge in der Schleppnetzfischerei auf Plattfische mit einem im Oberblatt reduziertem Grundschleppnetz

Trials with the “topless” version (with reduced upper panel) of the bottom trawl resulted in a 63 % reduction of cod bycatch in numbers, compared to the complete trawl. Flounder catches increased by 120 % on average. Further modification of the net opening height to optimize the trawl performance are underway.

Ein Vorschlag zur Senkung des Schlepppwiderstandes von Grundschleppnetzen

Mathematical modelling shows that the projection area of the trawl twine influencing its hydrodynamic resistance can be reduced by approx. 30 % through increasing the mesh size of the trawl wings and the conical parts of the trawls, in combi-nation with the use of thinner twine. The interrelation between fuel consumption and projection area of the trawl twine as well as the influence of the enlarged meshes of the wings and first panels on the catch composition can only be measured by trials on fishing boats.

Alternative Fangmethoden aus der Sicht der Fischereiforschung

Fischfanggeräte werden in der kommerziellen Fischerei und in der Fischereiforschung eingesetzt. In beiden Fällen werden hauptsächlich Schleppnetze verwendet. Schleppnetze sind jedoch nicht für alle Aufgabenstellungen der Fischereiforschung geeignet. Alternative in der Forschung verwendbare Untersuchungsgeräte und Methoden wurden bisher ohne überzeugenden Erfolg getestet. Schleppnetzen – insbesondere den Grundschleppnetzen der Berufsfischerei – werden sowohl die Meeresumwelt schädigende Einflüsse als auch unzureichende selektive Eigenschaften hinsichtlich Ziel- und Beifangarten nachgesagt. Die in der kommerziellen Fischerei der Ostsee verwendeten Schleppnetze üben aber nur einen geringen schädlichen Einfluss auf Bodenorganismen aus. Alternative ökosystemgerechte Fanggeräte wie Fischfallen können Schleppnetze bisher nicht ersetzen. Es werden Möglichkeiten aufgezeigt, die negativen Einflüsse auf die Meeresumwelt noch weiter zu verringern. Durch konstruktive Gestaltung der Schleppnetze (großmaschige Unterblätter im Vornetz, im Oberblatt reduzierte Grundschleppnetze) können Beifänge reduziert werden. Durch weitere Verbesserungen der Beschwerungs- und Spreizelemente an Grundschleppnetzen lassen sich die negativen Einflüsse auf den Meeresboden weiter reduzieren.

Der Haftwasseranteil bei Heringsanlandungen über Bandwaagen

In 2004 the fish processing company Euro-Baltic Fischverarbeitungs GmbH Mukran, went into operation on the Isle of Rügen at the Baltic coast of Germany. About 20 % of the herring landed there is discharged from the cutters into the processing plant by pipes, driven by pumps, in case that the landed volume exceeds 10 t fresh weight. In such case the herring is transported in water suspension by means of a pressure-vacuum suction pump system into containers and further transported via conveyer belt to a flowscale. During this process most of the water runs off. It is however unknown how much water remains with the fish and is eventually weighted as fish. To estimate this proportion the mixture of water and fish was stored in special transport containers, which allow the measurement of the run-off. As a result the study shows that on average 2 % of weight measured by the tape scale is water. Along with this factors were determined which influence the variability of the proportion of water.

Der Anteil Transportwasser bei Heringsanlandungen mittels Vakuumsauganlage in Großraumbehältern

Estimation of the water content of herring landings caused by pressure-vacuum double tank pumps and using of multi purpose transport containers About 80 % of herring that is landed in the fish processing company Euro-Baltic Fischverarbeitungs GmbH Mukran, on the Isle of Rügen at the Baltic coast is transported from the cutter into the processing plant by pumping. For this purpose 700 l-Euro-size polyethylene tubs (containers) are filled with herring by means of a pressure-vacuum pump-systems during the unloading of the cutter. To be able to pump the fish from the hold on board it is kept floating in water (transport water). At the end of the pumping/transporting process the fish ends in a dewatering box before reaching the tub, where the transport water is separated from the fish. Then, the not completely dewatered fish is slipped into the transport containers. The amount of transport water reaching the containers depends on the type of PV-equipment and on the amount of transport water in the fish holds of the different cutters. Methodologically the mixture of fish and water must be weighed together. For the experiments specially designed transport container were used which allow the measurement of the run-off of the water to be quantified and thus to measure the proportion of water remaining with the fish. Based on 30 experiments it could be shown that on average 6 % of remaining weight of the mixture is water. Furthermore, factors were detected which influence the variability of the proportion of water.

Horizontale Trennblätter in Trawls zur Verringerung von Discards in der Ostsee

A primary objective of the Common Fishery Policy of the European Union is the reduction of discards and unwanted by-catches in the fishery. In principle this could be achieved if the catching methods were optimised for this. Still high numbers of undersized flatfish are caught in the bottom trawls. Although EU regulations make the use of the BACOMA codend mandatory in the Baltic Sea cod areable to escape through square mesh escape window of the BACOMA net the whereas flatfish still remain in the cod-end. Gear experiments have been carried out with the aim to better separate cod from the flatfish fraction already when entering the rear belly, making use of the natural behaviour of the fish, i. e. the preferred swimming distance from the bottom of the net in the funnel. As cod have a natural tendency to keep a relativly great distance from the bottom, flatfish tend to stay close to it. It was attempted to separate both fractions by splitting the funnel into an upper and lower part with a horizontal panel. This wastested for two different nets, a cod trawl to separate cod from flatfish, and an eel-trawl to separate cod and flatfish from eel. Cod and flatfish separation is best at a panel distance of 50 cm from the bottom. Thus, 74 % of the cod were found in the upper panel, whereas 75 % of the flounder were in the lower section. A separation of eel from cod was however not possible, since eel tend to rise to the upper part of the net, together with cod.

Test von Fanggeräten zur Untersuchung von Grundfischfaunen in Windparkgebieten der Ostsee

With respect to future environmental impact assessment different bottom trawls are presently investigated for their suitability for sampling the fish fauna in potential windpark areas asses. For this purpose the international Baltic Sea Trawl, the Box trawl, two different small beam trawls and small eel fykes were compared on a research cutter in June 2002. The best catchability with the highest abundance of demersal fish species and widest length distribution was obtained with the Box trawl. During another cruise in December 2002 the Box trawl was again compared with the Windpark trawl. As a result the Box trawl performed best, with regard to the overall catchability. However the Windpark Trawl is easier to handle under the conditions onboard small fishing cutters.