Le général de Gaulle vu par André Malraux - héros national ou européen ?

A partir du portrait de Charles de Gaulle brossé par André Malraux dans Les Chênes qu’on abat (1971), l’article cherche à analyser et à évaluer le statut de ce héros national français afin de déterminer dans quelle mesure le général peut être considéré comme un grand homme de l’Europe. Le statut et le destin du général étant étroitement liés à ceux de la France, l’article tente de caractériser la place de ce grand homme ainsi que celle de la France dans l’Europe d’après la Deuxième Guerre mondiale. Les deux perspectives temporelles de la durée, d’une part, et des événements, de l’autre, contribuent ici à nuancer le portrait de ce grand homme à la fois profondément engagé dans l’histoire de son temps et pourtant représentant d’une continuité historique. Mots-clé: de Gaulle, Malraux, France, Europe, héros, nation

Présentation du Colloque international de Belfast du 30 août au 1er septembre 2007 « André Malraux et les valeurs spirituelles du XXIe siècle »

The article presented to Malraux specialists the conclusions and findings of the international conference on André Malraux held at Queen's University Belfast in 2007.

Les deux André et le concept de la durée: André Chamson et André Malraux dans le même combat pour les valeurs spirituelles.

Les vies et les carrières d’André Chamson et d’André Malraux se ressemblent par de multiples aspects. Contemporains, ils se connaissaient bien, menaient souvent les mêmes combats, souffraient des mêmes préoccupations, Mais c’est surtout par rapport à l’esprit qui les animait, en tant que grandes personnalités marquantes du XXe siècle, que d’intéressants parallèles peuvent être établis entre eux, que nous pouvons avec profit examiner les valeurs universelles et spirituelles qu’ils promouvaient, valeurs emblématiques pour tant de penseurs, d’acteurs, et d’écrivains de ce siècle. Ainsi pourrions-nous par ailleurs interroger et même évaluer la solidité, la résistance et le potentiel de telles valeurs pour le siècle à venir.

Defining the role of common variation in the genomic and biological architecture of adult human height

Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated 1/42,000, 1/43,700 and 1/49,500 SNPs explained 1/421%, 1/424% and 1/429% of phenotypic variance. Furthermore, all common variants together captured 60% of heritability. The 697 variants clustered in 423 loci were enriched for genes, pathways and tissue types known to be involved in growth and together implicated genes and pathways not highlighted in earlier efforts, such as signaling by fibroblast growth factors, WNT/I 2-catenin and chondroitin sulfate-related genes. We identified several genes and pathways not previously connected with human skeletal growth, including mTOR, osteoglycin and binding of hyaluronic acid. Our results indicate a genetic architecture for human height that is characterized by a very large but finite number (thousands) of causal variants.

As aprendizagens não formais e informais no ingresso à Escola Secundária Padre António Macedo: possíveis parcerias com outras instituições de Vila Nova de Santo André

Esta investigação teve como principal objectivo avaliar da presença dos contextos institucionais não formais e informais no conjunto das aprendizagens reveladas pelos estudantes que ingressaram, na Escola Secundária Padre António Macedo, no ano lectivo 2009-2010, e averiguar qual o contributo das instituições locais no seu percurso de aprendizagem. A abordagem metodológica assentou num dispositivo de matriz quantitativa, com o recurso ao inquérito por questionário a uma amostra de alunos. Observámos um potencial educativo na cidade proporcionado por instituições, onde se destacaram amigos, familiares e clubes desportivos, procurados pelos jovens para satisfazer a sua necessidade de conhecimento e ocupar tempos livres. Sendo as áreas com mais episódios de aprendizagens, extra escolares: saúde, cidadania, desporto e artes, os jovens reconheceramse detentores de conhecimentos propiciados pela comunidade e instituições locais; ABSTRACT: This research had, as main aim, to assess the presence of formal and informal institutional contexts in all the learnings revealed by the students who enrolled Escola Secundária Padre António Macedo in the year 2009-2010, and also to determine what contribution local institutions had in their learning. The methodological approach was based on a quantitative matrix device, by applying a questionnaire survey to a sample of students. We saw an educational potential offered by institutions in the city, where the highlights were friends, family and sports clubs, popular among young people to satisfy their need for knowledge and to occupy their free time. The areas with more episodes of extra school learning were: health, citizenship, sport and arts. Young people recognized themselves in possession of knowledge provided by the community and local institutions.

Are older people prescribed antidepressants on the basis of fewer symptoms of depression, and for longer periods of time? A survey of 1825 New Zealanders

Aims: To determine whether older people are prescribed antidepressants at lower levels of depression and with fewer symptoms, and whether they are more likely to engage in chronic usage. Methods: An online survey about experiences with, and opinions about, depression and antidepressants, was completed by 1,825 New Zealand adults who had been prescribed antidepressants in the preceding five years. Results: Participants over 55 were prescribed antidepressants with significantly fewer symptoms and were significantly less likely to meet DSM criteria for depression. They were also significantly more likely to have used the drugs for three years and still be using them. Conclusions: Prescribing physicians and their older patients might benefit from discussing the pros and cons of antidepressants (including the additional risk factors with this age group) and the alternatives; and, if prescription does occur, careful monitoring to avoid unnecessary, potentially damaging, long-term use is recommended.

Contribuição dos métodos geofísicos para o modelo evolutivo da região de Santo André desde o último máximo glaciário

Tese de doutoramento, Geologia (Geologia Económica e do Ambiente), Universidade de Lisboa, Faculdade de Ciências, 2014