Alteration in neuromuscular function after a 5 km running time trial

The aim of this study was to characterize the effect of a 5 km running time trial on the neuromuscular properties of the plantar flexors. Eleven well-trained triathletes performed a series of neuromuscular tests before and immediately after the run on a 200 m indoor track. Muscle activation (twitch interpolation) and normalized EMG activity were assessed during maximal voluntary contraction (MVC) of plantar flexors. Maximal soleus H-reflexes and M-waves were evoked at rest (i.e. H (MAX) and M (MAX), respectively) and during MVC (i.e. H (SUP) and M (SUP), respectively). MVC significantly declined (-27%; P < 0.001) after the run, due to decrease in muscle activation (-8%; P < 0.05) and M (MAX)-normalized EMG activity (-13%; P < 0.05). Significant reductions in M-wave amplitudes (M (MAX): -13% and M (SUP): -16%; P < 0.05) as well as H (MAX)/M (MAX) (-37%; P < 0.01) and H (SUP)/M (SUP) (-25%; P < 0.05) ratios occurred with fatigue. Following exercise, the single twitch was characterized by lower peak torque (-16%; P < 0.001) as well as shorter contraction (-19%; P < 0.001) and half-relaxation (-24%; P < 0.001) times. In conclusion, the reduction in plantar flexors strength induced by a 5 km running time trial is caused by peripheral adjustments, which are attributable to a failure of the neuromuscular transmission and excitation-contraction coupling. Fatigue also decreased the magnitude of efferent motor outflow from spinal motor neurons to the plantar flexors and part of this suboptimal neural drive is the result of an inhibition of soleus motoneuron pool reflex excitability.

A aptidão dos pesquisadores brasileiros pertencentes aos programas de pós-graduação stricto sensu em Administração para pesquisas quantitativas

É crescente a pressão para a publicação de artigos em periódicos de renome. Ressalta-se que os artigos publicados nesses periódicos são cada vez mais empíricos e com utilização de técnicas estatísticas progressivamente mais sofisticadas. Para isso, é importante que existam pesquisadores e programas capacitados para a análise quantitativa de dados. Neste trabalho, apresentam-se os resultados de um survey realizado com pesquisadores nacionais para verificar seu grau de proficiência em métodos estatísticos. Constatou-se que pesquisadores e programas brasileiros estão menos preparados para o uso desses métodos em relação a pesquisadores norte-americanos, conforme pesquisa usada como referência. Sugere-se não só a preparação de professores e alunos em métodos quantitativos, mas, sobretudo, a existência de estruturas de apoio que possam dar suporte para a melhoria de trabalhos desse tipo.

A new paradigm of neuromuscular electrical stimulation for the quadriceps femoris muscle.

PURPOSE: Neuromuscular electrical stimulation (NMES) with large electrodes and multiple current pathways (m-NMES) has recently been proposed as a valid alternative to conventional NMES (c-NMES) for quadriceps muscle (re)training. The main aim of this study was to compare discomfort, evoked force and fatigue between m-NMES and c-NMES of the quadriceps femoris muscle in healthy subjects. METHODS: Ten healthy subjects completed two experimental sessions (c-NMES and m-NMES), that were randomly presented in a cross-over design. Maximal electrically evoked force at pain threshold, self-reported discomfort at different levels of evoked force, and fatigue-induced force declines during and following a series of 20 NMES contractions were compared between c-NMES and m-NMES. RESULTS: m-NMES resulted in greater evoked force (P < 0.05) and lower discomfort in comparison to c-NMES (P < 0.05-0.001), but fatigue time course and magnitude did not differ between the two conditions. CONCLUSIONS: The use of quadriceps m-NMES appears legitimate for (re)training purposes because it generated stronger contractions and was less discomfortable than c-NMES (due to multiple current pathways and/or lower current density with larger electrodes).

Wide-pulse-high-frequency neuromuscular stimulation of triceps surae induces greater muscle fatigue compared with conventional stimulation.

We compared the extent and origin of muscle fatigue induced by short-pulse-low-frequency [conventional (CONV)] and wide-pulse-high-frequency (WPHF) neuromuscular electrical stimulation. We expected CONV contractions to mainly originate from depolarization of axonal terminal branches (spatially determined muscle fiber recruitment) and WPHF contractions to be partly produced via a central pathway (motor unit recruitment according to size principle). Greater neuromuscular fatigue was, therefore, expected following CONV compared with WPHF. Fourteen healthy subjects underwent 20 WPHF (1 ms-100 Hz) and CONV (50 μs-25 Hz) evoked isometric triceps surae contractions (work/rest periods 20:40 s) at an initial target of 10% of maximal voluntary contraction (MVC) force. Force-time integral of the 20 evoked contractions (FTI) was used as main index of muscle fatigue; MVC force loss was also quantified. Central and peripheral fatigue were assessed by voluntary activation level and paired stimulation amplitudes, respectively. FTI in WPHF was significantly lower than in CONV (21,717 ± 11,541 vs. 37,958 ± 9,898 N·s P<0,001). The reductions in MVC force (WPHF: -7.0 ± 2.7%; CONV: -6.2 ± 2.5%; P < 0.01) and paired stimulation amplitude (WPHF: -8.0 ± 4.0%; CONV: -7.4 ± 6.1%; P < 0.001) were similar between conditions, whereas no change was observed for voluntary activation level (P > 0.05). Overall, our results showed a different motor unit recruitment pattern between the two neuromuscular electrical stimulation modalities with a lower FTI indicating greater muscle fatigue for WPHF, possibly limiting the presumed benefits for rehabilitation programs.

Trunk neuromuscular responses to a single whole-body vibration session in patients with chronic low back pain: a cross-sectional study.

OBJECTIVE: Whole-body vibration (WBV) exercise is progressively adopted as an alternative therapeutic modality for enhancing muscle force and muscle activity via neurogenic potentiation. So far, possible changes in the recruitment patterns of the trunk musculature after WBV remain undetermined. The main objective of this study was to evaluate the short-term effects of a single WBV session on trunk neuromuscular responses in patients with chronic low back pain (cLBP) and healthy participants. METHODS: Twenty patients with cLBP and 21 healthy participants performed 10 trunk flexion-extensions before and after a single WBV session consisting of five 1-minute vibration sets. Surface electromyography (EMG) of erector spinae at L2-L3 and L4-L5 and lumbopelvic kinematic variables were collected during the trials. Data were analyzed using 2-way mixed analysis of variance models. RESULTS: The WBV session led to increased lumbar EMG activity during the flexion and extension phases but yielded no change in the quiet standing and fully flexed phases. Kinematic data showed a decreased contribution to the movement of the lumbar region in the second extension quartile. These effects were not different between patients with cLBP and healthy participants. CONCLUSIONS: Increased lumbar EMG activity after a single WBV session most probably results from potentiation effects of WBV on lumbar muscles reflex responses. Decreased EMG activity in full trunk flexion, usually observed in healthy individuals, was still present after WBV, suggesting that the ability of the spine stabilizing mechanisms to transfer the extension torque from muscles to passive structures was not affected.

Áreas de Aptidão Prioritárias Para Habitação de Interesse Social o Caso da Cidade da Praia

Este estudo propõe uma discussão sobre aptidão locacional para habitação de interesse social, considerando factores socioeconómicos e ambientais. Seu objectivo principal é identificar e avaliar o potencial das áreas de aptidão prioritárias para habitação de interesse social. Não obstante a expansão da cidade, particularmente o crescimento de bairros clandestinos ocupar áreas novas e sobretudo áreas de restrições ambientais e legais, a hipótese de pesquisa admite que existe, na cidade de Praia, um potencial urbano instalado, que pode ser potenciado em favor da população de baixa renda, dando vazão à demanda por localização de Habitação de Interesse Social, minimizando a expansão da cidade e os custos económicos, sociais e ambientais inerentes. A pesquisa conforma-se pelos princípios do método de análise espacial (MC HARG, 1969), subsidiados por sistemas de apoio à decisão (SAATY, 1977) e a teoria da sintaxe espacial (HILLIER & HANSON, 1984), desenvolvendo-se em ambiente SIG, com suporte do aplicativo ArcGis. Desenvolve um modelo teórico baseado em restrições legais - ambientais e factores potenciadores da actividade habitacional de interesse social, calibrado pelo custo do solo, e consubstanciado num mapa descritor das áreas mais adequadas para a localização de habitação social. A principal conclusão confirma a hipótese de existirem, na cidade da Praia, áreas com aptidão habitacional segundo critérios sócias, económicos e ambientais que podem ser potenciados para localizar habitação de interesse social.

Combining heat stress and moderate hypoxia reduces cycling time to exhaustion without modifying neuromuscular fatigue characteristics.

PURPOSE: This study investigated the isolated and combined effects of heat [temperate (22 °C/30 % rH) vs. hot (35 °C/40 % rH)] and hypoxia [sea level (FiO2 0.21) vs. moderate altitude (FiO2 0.15)] on exercise capacity and neuromuscular fatigue characteristics. METHODS: Eleven physically active subjects cycled to exhaustion at constant workload (66 % of the power output associated with their maximal oxygen uptake in temperate conditions) in four different environmental conditions [temperate/sea level (control), hot/sea level (hot), temperate/moderate altitude (hypoxia) and hot/moderate altitude (hot + hypoxia)]. Torque and electromyography (EMG) responses following electrical stimulation of the tibial nerve (plantar-flexion; soleus) were recorded before and 5 min after exercise. RESULTS: Time to exhaustion was reduced (P < 0.05) in hot (-35 ± 15 %) or hypoxia (-36 ± 14 %) compared to control (61 ± 28 min), while hot + hypoxia (-51 ± 20 %) further compromised exercise capacity (P < 0.05). However, the effect of temperature or altitude on end-exercise core temperature (P = 0.089 and P = 0.070, respectively) and rating of perceived exertion (P > 0.05) did not reach significance. Maximal voluntary contraction torque, voluntary activation (twitch interpolation) and peak twitch torque decreased from pre- to post-exercise (-9 ± 1, -4 ± 1 and -6 ± 1 % all trials compounded, respectively; P < 0.05), with no effect of the temperature or altitude. M-wave amplitude and root mean square activity were reduced (P < 0.05) in hot compared to temperate conditions, while normalized maximal EMG activity did not change. Altitude had no effect on any measured parameters. CONCLUSION: Moderate hypoxia in combination with heat stress reduces cycling time to exhaustion without modifying neuromuscular fatigue characteristics. Impaired oxygen delivery or increased cardiovascular strain, increasing relative exercise intensity, may have also contributed to earlier exercise cessation.

Neuromuscular fatigue induced by whole-body vibration exercise

The aim of this study was to examine the magnitude and the origin of neuromuscular fatigue induced by half-squat static whole-body vibration (WBV) exercise, and to compare it to a non-WBV condition. Nine healthy volunteers completed two fatiguing protocols (WBV and non-WBV, randomly presented) consisting of five 1-min bouts of static half-squat exercise with a load corresponding to 50 % of their individual body mass. Neuromuscular fatigue of knee and ankle muscles was investigated before and immediately after each fatiguing protocol. The main outcomes were maximal voluntary contraction (MVC) torque, voluntary activation, and doublet peak torque. Knee extensor MVC torque decreased significantly (P < 0.01) and to the same extent after WBV (-23 %) and non-WBV (-25 %), while knee flexor, plantar flexor, and dorsiflexor MVC torque was not affected by the treatments. Voluntary activation of knee extensor and plantar flexor muscles was unaffected by the two fatiguing protocols. Doublet peak torque decreased significantly and to a similar extent following WBV and non-WBV exercise, for both knee extensors (-25 %; P < 0.01) and plantar flexors (-7 %; P < 0.05). WBV exercise with additional load did not accentuate fatigue and did not change its causative factors compared to non-WBV half-squat resistive exercise in recreationally active subjects.

Maladies auto-immunes neuromusculaires: diagnostic et prise en charge [Dysimmune neuromuscular disorders: diagnostic challenges and new ways of management].

This review describes some dysimmune neuromuscular disorders and their recent management: syndrome of peripheral nerve hyperexcitability (treatment of cramps, immunosuppressors); Guillain-Barré syndrome (new mechanisms and consensus treatment); chronic inflammatory demyelinating polyradiculoneuropathy (new indication for the use of pulse dexamethasone, new scores of activity); importance of subcutaneous immunoglobulin in multifocal motor neuropathy and of infusions of rituximab in myasthenia gravis; new entities in myositis and their treatment.

Aptidão agrícola de terras com estimativa de risco climático para a cultura do milho utilizando geoprocessamento

O objetivo deste trabalho foi determinar a aptidão agrícola das terras para cultura do milho em sistema de produção tecnificado, a partir de dados extraídos de levantamento de solos em escala 1:50.000 e da estimativa do risco climático, usando um sistema de informações geográficas. A área de estudo foi a bacia hidrográfica do rio Jardim, no Distrito Federal. Utilizou-se um modelo de balanço hídrico para simular o risco climático para a cultura do milho (Zea mays L.), considerando nove datas de plantio. Foram definidos valores quantitativos para cada um das propriedades condicionadoras da produtividade do milho em áreas de cerrado e, por meio de algoritmos de lógica booleana estabelecidos com base em critérios definidos em tabelas-guia previamente elaboradas, foram realizados cruzamentos consecutivos que permitiram a elaboração de mapas de aptidão agrícola das terras para a cultura do milho, com cinco classes, que evidenciaram a variação temporal da aptidão. Constatou-se que 66,5 % da área total não apresentou limitações físicas, 96% das terras foram restritas em fertilidade e o período de menor risco climático foi de 11 a 20/10.

Aptidão para reflorestamento das sub-bacias dos canais do Mangue e do Cunha, município do Rio de Janeiro

Avaliou-se a aptidão para reflorestamento das terras das partes não edificadas da vertente norte do maciço da Tijuca, sub-bacias dos canais do Mangue e do Cunha, com o intuito de subsidiar ações do Programa Mutirão Reflorestamento da Secretaria Municipal de Meio Ambiente do Rio de Janeiro. A avaliação da aptidão das terras estimou graus de limitação dos parâmetros: deficiência de nutrientes, deficiência de água, susceptibilidade à erosão e impedimentos ao manejo. Estes graus de limitação foram estimados para os componentes das unidades de mapeamento de solos, considerando as informações de solos e paisagens do mapeamento existente. Para a digitalização e organização das informações geradas, foram utilizados sistemas de informações geográficas. As seguintes classes de aptidão para reflorestamento foram determinadas: 11,2 % de Regular, 81,5 % de Restrita e 7,3 % de Inapta. A declividade representa o fator limitante de maior importância para as terras da classe de aptidão restrita, seguida da presença de rochosidade.

Avaliação da aptidão agrícola das terras como subsídio ao assentamento de famílias rurais, utilizando sistemas de informações geográficas

Os assentamentos rurais no Brasil foram criados para responder a pressões localizadas e estão marcados pela falta de planejamento prévio de implantação e diagnóstico dos recursos naturais relativos a aptidão agrícola, distribuição das classes de relevo, hidrografia, vegetação e mecanismos de apoio. O objetivo desta pesquisa foi avaliar a aptidão agrícola das terras destinadas ao assentamento de famílias rurais do Instituto Nacional de Colonização e Reforma Agrária (INCRA), aplicando o Sistema de Avaliação da Aptidão Agrícola das Terras (SAAT) associado a um Sistema de Informações Geográficas (SIG) no Projeto de Assentamento Eldorado dos Carajás (PAEC), localizado no município de Lebon Régis/SC. No desenvolvimento da pesquisa, optou-se por utilizar mapas temáticos em sistemas de informações geográficas (SIG) para armazenar e integrar os dados espaciais. O uso do SIG permitiu a análise e integração dos temas com significativa redução de tempo e subjetividade nos cruzamentos. O uso do método forneceu duas respostas básicas ao planejamento de uso dos recursos naturais das áreas rurais: as classes de aptidão agrícola, apontando os principais fatores limitantes e a viabilidade de melhoramento das terras no nível tecnológico B; e, quando confrontado com os mapas temáticos e os dados cadastrais do assentamento, revelou as regularidades e irregularidades no uso das terras em cada parcela imobiliária.

Aptidão agrícola e algoritmos genéticos na organização espacial em projetos de reforma agrária

A definição das parcelas familiares em projetos de reforma agrária envolve questões técnicas e sociais. Essas questões estão associadas principalmente às diferentes aptidões agrícolas do solo nestes projetos. O objetivo deste trabalho foi apresentar método para realizar o processo de ordenamento territorial em assentamentos de reforma agrária empregando Algoritmo Genético (AG). O AG foi testado no Projeto de Assentamento Veredas, em Minas Gerais, e implementado com base no sistema de aptidão agrícola das terras.

Neuromuscular fatigue in racquet sports

This article describes the physiologic and neural mechanisms that cause neuromuscular fatigue in racquet sports: table tennis, tennis, squash, and badminton. In these intermittent and dual activities, performance may be limited as a match progresses because of a reduced central activation, linked to changes in neurotransmitter concentration or in response to afferent sensory feedback. Alternatively, modulation of spinal loop properties may occur because of changes in metabolic or mechanical properties within the muscle. Finally, increased fatigue manifested by mistimed strokes, lower speed, and altered on-court movements may be caused by ionic disturbances and impairments in excitation-contraction coupling properties. These alterations in neuromuscular function contribute to decrease in racquet sports performance observed under fatigue.