School of Nursing Class of 2008

Top Row: Therese Adamowski, Anel Adamson, Michelle Ahleman, Brooke Babineau, Jennifer Ballough, Lisa Anne Beckman, Jennifer Bergeren, Tedra Boedigheimer, Mary Bonner, Genevieve Bott, Megan Bouwhuis, Mitchell Bradley, Rachel Brown, Katherine Bulson, Jennifer Calhoun, Carley Cebelak, Sarah Choinard

Row 2: Sarah Clevenger, Elizabeth Anne Conway, Erin Coughlin, Karie Curtis, Stephanie Curtis, Jodi Danhof, Rebecca Debri, Stacie Deleszek, Andrea Dehline, Amanda Devlin, Charlotte Dietrich, Angela Dodge, Elizabeth Dougherty, Ashley Doyle, Lindsay Driver, Nancy Duckworth, Kathy Dunnuck, Jennifer Dziadaio, Ellen English

Row 3: Kelly Esser, Amanda Fender, Lindsey Smith, Andrew Bradburn, Fallon Garfield Turner, Margaret Dembeck, Courtney Van Essen, Jessica paige Smith, Lauren Inouye, Jacqueline Dufek, Emily Klump, Amanda Jones, Tiffany Burrell, Deborah Mitchell, Emily Michel, Michelle Steen, Kirsten Thulin, Emily Hautamaki, Sheila Fender, Keith Ferguson

Row 4: Annie Fields, Jillian Fisher, Erin Flatley, Renee Forma, Aileen Franchi, Lindsey Freysinger, Sarah Fulgenzi, Beth Funnell, Andrea Galaviz, Lacey Garbo, Katherine Garcia, Lynn Garofalo

Row 5: Heather Gehrke, Nicole Genrich, Katie Giordano, Lindsey Glover, Andrea Godfrey, Jocelyn Gossman, Alana Greenberg, Julien Guttman, Sarah Halfmann, Kimberly Hanger, Allison Hanson, Stephanie Hecklin

Row 6: Geri Helminiak, Kristi Hershiser, Erin Hipp, Amanda Hoath, Tracy Hurlbutt, Nadya Indrei, Nisa Joorabchi, Katy Kerrigan, Layne Kiella, Jessica Kim, Samantha Klaiman, Jodi Knight, Laura Kovacic, Alicia Kreger

Row 7: Amanda Kretsch, Kimberly Kurzeja, Julie Lamonoff, Sarah Leirstein, Ashley Labb, Suzanne Loeb, Alessandra Lollini, Heather Loomis, Caroline Luke, Stephanie Maniquis, Elizabeth Mann, LaTasha Marable, Amanda McAdams, Mara McKinley

Row 8: Leah McLaughlin, Erin Migda, Scott Migut, Joane Nwoke, Lazarus Okammor, Brittany Pajewski, Judith Lynch-Sauer, Patricia Coleman-Burns, Bonnie Hagerty, Kathleen Potempa, Carol Loveland-Cherry, Carolyn Sampselle, Joanne Pohl, Sarah Pajtas, Maria Paneda, Jennifer Parker, Carol Peterson, Kimberley Peven, Rachel Poterek, Sarah Poucher

Row 9: Jannet Provost, Jessica Quigley, Nicole Rasmuson, Joanthan Reed, Sharon Reske, John Reves, Amy Riebe, Sara Riegner, Kelly Risicato, Christine Sabado, Stephanie Sargent, Jolene Schaefer, Erin Schroeder, Catherine Scott, Katherine See, Andrea Semaan, Jessica Shantz, Kathryn Sibbold, Kathleen Skendrovic, Aaron Smith, Elizabeth Stanton

Row 10: Mary Stewart, Ashley Strotbaum, Danielle Swartz, Janet Trost, Elizabeth Underwood, Lauren Underwood, Allison Vanhall, Brian Velker, Kristen Wells, Ryan Werblow, Jennifer Werden, David Westrin, Mallory Wiesen, Karen Wingrove, Amy Wright, Carrie Wright, Emily Wright, Minou Xie, Charles Zimmerman

School of Nursing Class of 2011

Top Row: Dereje Amente, Grace Baek, Anne Benitez, Anna Berry-Krumrey, Amber Blake, Daniela Bravo-Corona, Shelley Brenner, Melissa Butzky, Ann Cassel, Chantal Chin, Mee-Sook Choo, Stephanie Clapham, Kathryn Clark, Joseph Cleary, Stephanie Conn, Casie Cook

Row 2: Christina Cook, Jessica Cook, Renea Cox, Marissa DaSilva, Kathryn Davenport, Ashley Deford, Alyse DeHaan, Maria Didio, Alyssa Diroff, Amy Doenitz, Emily Domansky, Deanna Dong, Ross Drake, Brian Dulzo, Michelle Dwyer, Jill Eberly, Rachel Escobar, Kathryn Falvey

Row 3: Michelle Fauver, Paula Fe Francisco, Lindsey Frick, Amannda Casper, Ashley Pickett, Kristin Kingma, Thomas Donnelly, Danielle Besk, Kimberly Cristobal, Heather Erdmann, Jessica Kramer, Ana Kotsogiannis, Sarah Bloom, Anna Evola, Melissa Dulic, Anna Garcia, Christopher Gargala, Thomas Geigert

Row 4: Megan Giles, Kristen Gniewkowski, Alexandra Gold, Sarah Gorzalski, Michele Grabow, Amber Gramling, Hannah Gregerson, Maria Hegan, Wendy Hastings, Ahsley Hayner

Row 5: Leanne Heilig, Lauryn Hildensperger, Rachel Hollern, Laura Jean Howatt, Eve Jaehnen, Stephanie Johnson, Peter Kachur, Rachelle Kilburg, Rachel Klein, Sara Klok, Caitlyn Kochanski, Valerie Kotal

Row 6: Lidia Kraft, Allison Kruger, Omotara Kufeji, Jill Kuhlman, Karah Kurdys, Kathryn Lang, Elsa Lindquist, Sara Mangus, Kathryn Marten, Samantha Maskell, Lauren McBride, Kelly McCarley

Row 7: Rachel McClure, Angela McCracken, Mallory Missad, Kathleen Murray, Mariko Nakagawa, Jaclyn Nancekivell, Tracey Negrelli, Kathleen Potempa, Bonnie Hagerty, Healee On, Sarah Osentoski, Kelsey Owens, Kelly Paulisin, Amanda Phillips, Emily Pressley, Kaitlyn Radius

Row 8: Rebecca Reits, Elin Ridenour, Amanda Robbins, Chayla Robles, Jessica Roossien, Alyssa Roy, Leslie Russell, Kristen Ruster, Cynthia Scheuher, Julie Schramm, Kim Schroers, Jennifer Schwartz, Kelly Seestedt, Shannon shank, Andrea Sherzer, Lauren Sir, Erinn Smith, Kathleen Soedarjatno

Row 9: Jessica Stefko, Alexandra Stencel, Brianne Stowell, Alexandra Suseland, Lauren Taylor, Deborah Thornton, Amanda Timmer, Daniel Tjarks, Jillian Traskos, Graham Valley, Sarah Wade, Rachel Wagner, Drew Wakefield, Marlena Westerlund, Katie Wheelock, Jennifer Wilcox, Dana York

Data compilation on the biological response to ocean acidification: environmental and experimental context of data sets and related literature

The exponential growth of studies on the biological response to ocean acidification over the last few decades has generated a large amount of data. To facilitate data comparison, a data compilation hosted at the data publisher PANGAEA was initiated in 2008 and is updated on a regular basis (doi:10.1594/PANGAEA.149999). By January 2015, a total of 581 data sets (over 4 000 000 data points) from 539 papers had been archived. Here we present the developments of this data compilation five years since its first description by Nisumaa et al. (2010). Most of study sites from which data archived are still in the Northern Hemisphere and the number of archived data from studies from the Southern Hemisphere and polar oceans are still relatively low. Data from 60 studies that investigated the response of a mix of organisms or natural communities were all added after 2010, indicating a welcomed shift from the study of individual organisms to communities and ecosystems. The initial imbalance of considerably more data archived on calcification and primary production than on other processes has improved. There is also a clear tendency towards more data archived from multifactorial studies after 2010. For easier and more effective access to ocean acidification data, the ocean acidification community is strongly encouraged to contribute to the data archiving effort, and help develop standard vocabularies describing the variables and define best practices for archiving ocean acidification data.

Profile Of The Use Of Disease Modifying Drugs In The Brazilian Registry Of Spondyloarthritides.

Few studies have evaluated the profile of use of disease modifying drugs (DMD) in Brazilian patients with spondyloarthritis (SpA). A common research protocol was applied prospectively in 1505 patients classified as SpA by criteria of the European Spondyloarthropathies Study Group (ESSG), followed at 29 referral centers in Rheumatology in Brazil. Demographic and clinical variables were obtained and evaluated, by analyzing their correlation with the use of DMDs methotrexate (MTX) and sulfasalazine (SSZ). At least one DMD was used by 73.6% of patients: MTX by 29.2% and SSZ by 21.7%, while 22.7% used both drugs. The use of MTX was significantly associated with peripheral involvement, and SSZ was associated with axial involvement, and the two drugs were more administered, separately or in combination, in the mixed involvement (p < 0.001). The use of a DMD was significantly associated with Caucasian ethnicity (MTX , p = 0.014), inflammatory back pain (SSZ, p = 0.002) , buttock pain (SSZ, p = 0.030), neck pain (MTX, p = 0.042), arthritis of the lower limbs (MTX, p < 0.001), arthritis of the upper limbs (MTX, p < 0.001), enthesitis (p = 0.007), dactylitis (MTX, p < 0.001), inflammatory bowel disease (SSZ, p < 0.001) and nail involvement (MTX, p < 0.001). The use of at least one DMD was reported by more than 70% of patients in a large cohort of Brazilian patients with SpA, with MTX use more associated with peripheral involvement and the use of SSZ more associated with axial involvement.

Characterization Of Microsatellite Markers Developed From Prosopis Rubriflora And Prosopis Ruscifolia (leguminosae - Mimosoideae), Legume Species That Are Used As Models For Genetic Diversity Studies In Chaquenian Areas Under Anthropization In South America.

Prosopis rubriflora and Prosopis ruscifolia are important species in the Chaquenian regions of Brazil. Because of the restriction and frequency of their physiognomy, they are excellent models for conservation genetics studies. The use of microsatellite markers (Simple Sequence Repeats, SSRs) has become increasingly important in recent years and has proven to be a powerful tool for both ecological and molecular studies. In this study, we present the development and characterization of 10 new markers for P. rubriflora and 13 new markers for P. ruscifolia. The genotyping was performed using 40 P. rubriflora samples and 48 P. ruscifolia samples from the Chaquenian remnants in Brazil. The polymorphism information content (PIC) of the P. rubriflora markers ranged from 0.073 to 0.791, and no null alleles or deviation from Hardy-Weinberg equilibrium (HW) were detected. The PIC values for the P. ruscifolia markers ranged from 0.289 to 0.883, but a departure from HW and null alleles were detected for certain loci; however, this departure may have resulted from anthropic activities, such as the presence of livestock, which is very common in the remnant areas. In this study, we describe novel SSR polymorphic markers that may be helpful in future genetic studies of P. rubriflora and P. ruscifolia.

Effect Of Exercise Test On Pulmonary Function Of Obese Adolescents.

to investigate the pulmonary response to exercise of non-morbidly obese adolescents, considering the gender. a prospective cross-sectional study was conducted with 92 adolescents (47 obese and 45 eutrophic), divided in four groups according to obesity and gender. Anthropometric parameters, pulmonary function (spirometry and oxygen saturation [SatO2]), heart rate (HR), blood pressure (BP), respiratory rate (RR), and respiratory muscle strength were measured. Pulmonary function parameters were measured before, during, and after the exercise test. BP and HR were higher in obese individuals during the exercise test (p = 0.0001). SatO2 values decreased during exercise in obese adolescents (p = 0.0001). Obese males had higher levels of maximum inspiratory and expiratory pressures (p = 0.0002) when compared to obese and eutrophic females. Obese males showed lower values of maximum voluntary ventilation, forced vital capacity, and forced expiratory volume in the first second when compared to eutrophic males, before and after exercise (p = 0.0005). Obese females had greater inspiratory capacity compared to eutrophic females (p = 0.0001). Expiratory reserve volume was lower in obese subjects when compared to controls (p ≤ 0,05). obese adolescents presented changes in pulmonary function at rest and these changes remained present during exercise. The spirometric and cardiorespiratory values were different in the four study groups. The present data demonstrated that, in spite of differences in lung growth, the model of fat distribution alters pulmonary function differently in obese female and male adolescents.

Control Of The Properties Of Porous Chitosan-alginate Membranes Through The Addition Of Different Proportions Of Pluronic F68.

This work addresses the development and characterization of porous chitosan-alginate based polyelectrolyte complexes, obtained by using two different proportions of the biocompatible surfactant Pluronic F68. These biomaterials are proposed for applications as biodegradable and biocompatible wound dressing and/or scaffolds. The results indicate that thickness, roughness, porosity and liquid uptake of the membranes increase with the amount of surfactant used, while their mechanical properties and stability in aqueous media decrease. Other important properties such as color and surface hydrophilicity (water contact angle) are not significantly altered or did not present a clear tendency of variation with the increase of the amount of surfactant added to the polyelectrolyte complexes, such as real density, average pore diameter, total pore volume and surface area. The prepared biomaterials were not cytotoxic to L929 cells. In conclusion, it is possible to tune the physicochemical properties of chitosan-alginate polyelectrolyte complexes, through the variation of the proportion of surfactant (Pluronic F68) added to the mixture, so as to enable the desired application of these biomaterials.

Nasal Potential Difference In Cystic Fibrosis Considering Severe Cftr Mutations.

The gold standard for diagnosing cystic fibrosis (CF) is a sweat chloride value above 60 mEq/L. However, this historical and important tool has limitations; other techniques should be studied, including the nasal potential difference (NPD) test. CFTR gene sequencing can identify CFTR mutations, but this method is time-consuming and too expensive to be used in all CF centers. The present study compared CF patients with two classes I-III CFTR mutations (10 patients) (G1), CF patients with classes IV-VI CFTR mutations (five patients) (G2), and 21 healthy subjects (G3). The CF patients and healthy subjects also underwent the NPD test. A statistical analysis was performed using the Mann-Whitney, Kruskal-Wallis, χ(2), and Fisher's exact tests, α = 0.05. No differences were observed between the CF patients and healthy controls for the PDMax, Δamiloride, and Δchloride + free + amiloride markers from the NPD test. For the finger value, a difference between G2 and G3 was described. The Wilschanski index values were different between G1 and G3. In conclusion, our data showed that NPD is useful for CF diagnosis when classes I-III CFTR mutations are screened. However, if classes IV-VI are considered, the NPD test showed an overlap in values with healthy subjects.

Diretrizes curriculares nacionais para o ensino médio: avaliação de documento

This text offers some contributions to the debate on the changes proposed to the National Curricular Directives to reform secondary education in Brazil. In the first part, the political and economic scene is evaluated as the context which generated the last stage of reforms in the educational field in the 90s. It questions the option for a model of structural reform (in the Brazilian case more restricted to the Program for Reform of Professional Education - PROEP) and of the curriculum, whose themes find their justification in the contemporary economic, social cultural and political context. It discusses the use of a model that bases itself on experiences developed in other countries and takes the international orientation of the multilateral organizations as its theoretical methodological reference, leaving out the peculiarities and injunctions of the Brazilian political administrative system. Such a policy measure can increase the tension and distance normally existing between government programs and the possibility of their real implementation in the school network. In the second part, it discusses the Resolution of the National Education Council, the Congress on Basic Education, no.3, of 16.698 that instituted the National Curricular Directives for secondary education, as well as the Legal Bases - Part I - of the National Curricular Parameters for secondary education. The analysis of official discourse takes Bardin's (1977, p. 209) proposals as its methodological reference for the models of structural analysis, seeking to make the implicit values and the connotations of the legal texts explicit

Antimycobacterial and cytotoxicity activity of synthetic and natural compounds

Antimycobacterial and cytotoxicity activity of synthetic and natural compounds. Secondary metabolites from Curvularia eragrostidis and Drechslera dematioidea, Clusia sp. floral resin, alkaloids from Pilocarpus alatus, salicylideneanilines, piperidine amides, the amine 1-cinnamylpiperazine and chiral pyridinium salts were assayed on Mycobacterium tuberculosis H37Rv. N-(salicylidene)-2-hydroxyaniline was the most effective compound with a minimal inhibitory concentration (MIC) of 8 µmol/L. Dihydrocurvularin was moderately effective with a MIC of 40 µmol/L. Clusia sp. floral resin and a gallocatechin-epigallocatechin mixture showed MIC of 0.02 g/L and 38 µmol/L, respectively. The cytotoxicity was evaluated for N-(salicylidene)-2-hydroxyaniline, curvularin, dihydrocurvularin and Clusia sp. floral resin, and the selectivity indexes were > 125, 0.47, 0.75 and 5, respectively.

Endocrinologia pediátrica 2011

499

Interaction between staining and degradation of a composite resin in contact with colored foods

Composite resins might be susceptible to degradation and staining when in contact with some foods and drinks. This study evaluated color alteration and changes in microhardness of a microhybrid composite after immersion in different colored foods and determined whether there was a correlation between these two variables. Eighty composite disks were randomly divided into 8 experimental groups (n = 10): kept dry; deionized water; orange juice; passion fruit juice; grape juice; ketchup; mustard and soy sauce. The disks were individually immersed in their respective test substance at 37 ºC, for a period of 28 days. Superficial analysis of the disk specimens was performed by taking microhardness measurements (Vickers, 50 g load for 45 seconds) and color alterations were determined with a spectrophotometer (CINTRA 10- using a CIEL*a*b* system, 400-700 nm wavelength, illuminant d65 and standard observer of 2º) at the following times: baseline (before immersion), 1, 7, 14, 21 and 28 days. Results were analyzed by ANOVA and Tukey's test (p < 0.05). Both variables were also submitted to Pearson's correlation test (p < 0.05). The passion fruit group underwent the greatest microhardness change, while the mustard group suffered the greatest color alteration. Significant positive correlation was found between the two variables for the groups deionized water, grape juice, soy sauce and ketchup. Not all color alteration could be associated with surface degradation.

Psychological stress and recurrent aphthous stomatitis

INTRODUCTION AND OBJECTIVES: Recurrent aphthous stomatitis (RAS) is the most common type of ulcerative disease of the oral mucosa. Despite its worldwide occurrence and the extensive amount of research that has been devoted to the subject, the etiology of RAS remains unclear. Nevertheless, several hereditary, nutritional, infectious and psychological factors have been associated with RAS. The aim of this case-control study was to assess the influence of psychological stress on the manifestation of RAS. METHOD: Fifty patients were enrolled in the trial. Twenty-five RAS patients constituted the study group and another 25 non-RAS patients who were similarly matched for sex, age and socioeconomic status constituted the control group. Each patient was evaluated in terms of the four domains of stress (emotional, physical, social and cognitive) using an internationally validated questionnaire, which was comprised of 59 items and measured the frequency and intensity of stress symptoms. The RAS group was interviewed during an active RAS episode. Completed questionnaires were submitted to proper analytical software and interpreted by an expert psychologist. RESULTS: There was a higher level of psychological stress among RAS group patients when compared to the control group (P < 0.05). CONCLUSION: Psychological stress may play a role in the manifestation of RAS; it may serve as a trigger or a modifying factor rather than being a cause of the disease.