100 resultados para 3898
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Mode of access: Internet.
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There has been concern in the literature about the adequacy of the traditional model of marketing planning, which focuses on what decisions should be made and not on how to make them. The aim of this article is a new conceptualisation that proposes key management processes about how marketing planning decisions are made in a dynamic context. The motives for this conceptualisation are to contribute to understanding by advancing the traditional model of marketing planning, to stimulate academic and practitioner debate about how marketing planning decisions are made, and to initiate new directions in marketing planning research. Two new competing models of marketing planning are developed, which address key management processes about how marketing planning decisions are made in a dynamic context, and research directions are proposed.
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On the basis of a long term research of the authors a database model of grain size composition of unlithified marine and ocean bottom sediments has been created. An improved method of water-mechanical analysis has been offered. Grain size parameters of main types of bottom sediments have been measured and calculated. The genetic interpretation of results and regularities of sandy, aleuritic and pelitic material in basins of sedimentation are under discussion.
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In this article I explore how the figure of debt illuminates the racial politics of welfare in neoliberal Britain. I begin by giving a reading of the simultaneous unfolding of post-war race politics and the Beveridgean welfare state, and then turn to consider the interpellative appeal of neoliberal debt to minoritiSed subjects who have, in certain respects, been de facto excluded from prevailing models of welfare citizenship. In particular, this article considers the ways in which household debt might, even as it increases social inequality, simultaneously produce ideas about equality and futurity, as well as gesture towards the possibility of post-national forms of identity and belonging. If we are to challenge the lowest-common-denominator logics of ‘capitalist realism’ it is necessary to develop orientations to the economic that are as convincing as the popular stories that circulate about the operations of the neoliberal marketplace, and which are as meaningful as the social relations they play a part in constituting. Rather than reproduce the racialized model of welfare citizenship that is implicit to the ‘defence’ of the postwar welfare state, I suggest that there are elements of prevailing neoliberal market relations that might themselves serve as a more substantial basis for expressions of racial equality. There is, in other words, something that we can learn from neoliberal debt regimes in order to develop a more egalitarian future-oriented politics of social welfare and economic redistribution.
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The devolution of powers from Westminster to the Northern Ireland Assembly, the Scottish Parliament and the National Assembly for Wales led to much speculation about the creation of a new political era that would herald new ways of 'doing politics'. It was thought that the new institutions would provide a more inclusive, less combative culture that aimed to include a greater proportion of women members. With the 'new' institutions now over ten years old, linguistic research into the participation of men and women on the debate floor shows that they participate more equally and that improvements have been made in relation to the extent that women feel included. However, the devolved institutions retain some of the adversarial features associated with Westminster, and women are still subject to the burden of gendered stereotypical judgements and expectations that may affect their performance and inclusion within them.
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Tesis (Maestría en Docencia). -- Universidad de la Salle. Facultad de Ciencias de la Educación. Maestría en Docencia, 2015
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Recentemente tem-se assistido a um acumular de evidência sugerindo a implicação de uma desregulação do metabolismo do ferro (Fe) na fisiopatologia da doença de Alzheimer (DA). Neste trabalho, pretendemos esclarecer melhor os mecanismos moleculares subjacentes à homeostasia deste metal na DA, particularmente ao nível do efluxo celular. Assim, mediu-se em células mononucleares do sangue periférico de 73 doentes com DA e 74 controlos a expressão de genes diretamente envolvidos na regulação e exportação celular de Fe, utilizando a técnica de PCR quantitativo. Os resultados mostraram uma diminuição significativa na expressão dos genes aconitase (ACO1; P=0,007); ceruloplasmina (CP; P<0,001) e proteína precursora de beta amilóide (APP; P=0,006) em doentes com DA comparativamente com os voluntários saudáveis. Estas observações apontam para uma diminuição significativa da expressão dos genes associados com a exportação de Fe celular mediada pela ferroportina na DA. Assim, o presente estudo reforça resultados anteriores que mostram alterações no metabolismo do Fe e podem estar na origem da retenção intracelular deste metal e aumento de stress oxidativo caraterísticos desta patologia.
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International audience
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El estudio parte de que todo ser humano accede a la semiosis de la reproducción social, de su entorno existencial. Utilizando la noción de semiosfera (Lotman), y derivaciones conceptuales como la de texto, en un sentido amplificado, se analizan tres aspectos de la experiencia social de un individuo: el fenómeno de la otredad, geográfica y cultural; la ciudad como marca situacional e ideológica, incluido su tratamiento literario; y la conciencia de los contrastes en el devenir histórico de un país.The basis of this study is that all human beings are part of the semiosis of social reproduction, of their existential environment. Using the notion of semiosphere (Lotman), and conceptual derivations such as that of text, in a simplified sense, three aspects are analyzed regarding the social experience of an individual: the phenomenon of geographical and cultural othemess; the city as a situational and ideological sign, including its literary treatment; and the awareness of contrasts in a country's historical future.