General support maintenance manual (card test and repair) : radar set AN/TPQ-36 (NSN 5840-01-043-4257) and radar set AN/TPQ-37(V) (NSN 5840-01-043-4258).

"24 August 1982."

DrsG from Streptococcus dysgalactiae subsp equisimilis inhibits the antimicrobial peptide LL- 37

SIC and DRS are related proteins present in only four of the more than 200 Streptococcus pyogenes emm-types. These proteins inhibit complement mediated lysis and/or the activity of certain antimicrobial peptides. A gene encoding a homologue of these proteins, herein called DrsG, has been identified in the related bacterium Streptococcus dysgalactiae subsp equisimilis (SDSE). Here we show that geographically dispersed isolates representing 14 of 50 emm-types examined possess variants of drsG. However not all isolates within the drsG-positive emm-types possess the gene. Sequence comparisons also reveal a high degree of conservation in different SDSE emm-types. To examine the biological activity of DrsG, recombinant versions of two major DrsG variants, DrsGS and DrsGL, were expressed and purified. Western blot analysis using antisera raised to these proteins demonstrated both variants to be expressed and secreted into culture supernatant. Unlike SIC, but similar to DRS, DrsG does not inhibit complement mediated lysis. However, like both SIC and DRS, DrsG is a ligand of the cathelcidin LL-37 and is inhibitory to its bactericidal activity in in vitro assays. The greatest similarity between DrsG and DRS/SIC is found in the signal sequence at the amino terminus and proline rich domains in the C-terminal half of the protein. Conservation of prolines in this latter region also suggests these residues are important in the biology of this family of proteins. This is the first report demonstrating the activity of an AMP inhibitory protein in SDSE. These results also suggest that inhibition of AMP activity is the primary function of this family of proteins. The acquisition of complement inhibitory activity of SIC may reflect its continuing evolution.

Formation of amorphous xenon nanoclusters and microstructure evolution in pulsed laser deposited Ti(62.5)Si(37.5) thin films during Xe ion irradiation

As deposited amorphous and crystallized thin films of Ti 37.5% Si alloy deposited by pulsed laser ablation technique were irradiated with 100 keV Xe(+) ion beam to an ion fluence of about 10(16) ions-cm(-2). Transmission electron microscopy revealed that the implanted Xe formed amorphous nanosized clusters in both cases. The Xe ion-irradiation favors nucleation of a fcc-Ti(Si) phase in amorphous films. However, in crystalline films, irradiation leads to dissolution of the Ti(5)Si(3) intermetallic phase. In both cases, Xe irradiation leads to the evolution of similar microstructures. Our results point to the pivotal role of nucleation in the evolution of the microstructure under the condition of ion implantation.

Memory effect in SrRu(1-x)O3 (0.01 < x < 0.07)

SrRuO3 is widely known to be an itinerant ferromagnet with a T-C similar to 160 K. It is well known that glassy materials exhibit time dependent phenomena such as memory effect due to their generic slow dynamics. However, for the first time, we have observed memory effect in SrRu(1-x)O3 (0.01

[Discurso do Deputado Antônio Bresolin : Sessão da Câmara dos Deputados de 01 de julho de 1964]

Ressalta a importância do projeto de lei n. 1042 de 1963, que dispõe sobre a elaboração de um Plano Diretor Regional, ao qual ficará subordinada a utilização das áreas que constituem o Distrito Federal. Assinala as vantagens que teria o Prefeito de Brasília se viesse a rescindir os contratos de mansões e terrenos não pagos e os revendesse em seguida. Cita as possibilidades turísticas do Parque do Gama.

[Discurso do Deputado Arruda Câmara : Sessão da Câmara dos Deputados de 01 de julho de 1964]

Assinala as deficiências da cidade de Brasília. Ressalta a necessidade de que o Presidente da República e seus Ministros se instalem definitivamente na nova capital.

Edital nº 01/86 : concurso público para Técnico em Material e Patrimônio

Torna pública a abertura de inscrição para concurso público destinado ao preenchimento de cargos de Técnico em Material e Patrimônio, do Grupo-Atividades de Apoio Legislativo da Câmara dos Deputados.

Edital nº 01/77 : concurso público para Assessor Legislativo

Torna público as inscrições para concurso público destinado ao preenchimento de cargos em comissão de Assessor Legislativo da Câmara dos Deputados.

Salivary antimicrobial peptides (LL-37 and alpha-defensins HNP1-3), antimicrobial and IgA responses to prolonged exercise

There are many factors in mucosal secretions that contribute to innate immunity and the 'first line of defence' at mucosal surfaces. Few studies, however, have investigated the effects of exercise on many of these 'defence' factors. The aim of the present study was to determine the acute effects of prolonged exercise on salivary levels of selected antimicrobial peptides (AMP) that have not yet been studied in response to exercise (HNP1-3 and LL-37) in addition to immunoglobulin A (IgA). A secondary objective was to assess the effects of exercise on saliva antibacterial capacity. Twelve active men exercised on a cycle ergometer for 2.5 h at approximately 60% of maximal oxygen uptake. Unstimulated whole saliva samples were obtained before and after exercise. There was a significant decrease (P < 0.05) in salivary IgA:osmolality ratio, following exercise, but IgA concentration and secretion rate were unaltered. Salivary HNP1-3 and LL-37 concentrations (P < 0.01 and P < 0.05, respectively), concentration:osmolality ratios (P < 0.01) and secretion rates (P < 0.01) all increased following exercise. Salivary antibacterial capacity (against E. coli) did not change. The increased concentration of AMPs in saliva may confer some benefit to the 'first line of defence' and could result from synergistic compensation within the mucosal immune system and/or airway inflammation and epithelial damage. Further study is required to determine the significance of such changes on the overall 'defence' capacity of saliva and how this influences the overall risk for infection.

Unesp Ciência, 2012, ano 4, número 37

Revista elaborada pela Assessoria de Comunicação e Imprensa da Reitoria da UNESP

Pay roll voucher #37 from the Engineer Department of the Welland Railway for the Southern Division for the month of October

Pay roll voucher #37 from the Engineer Department of the Welland Railway for the Southern Division for the month of October, Nov. 6, 1857.